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HECTD2 Gene

protein-coding   GIFtS: 50
GCID: GC10P093160

HECT Domain Containing E3 Ubiquitin Protein Ligase 2

(Previous name: HECT domain containing 2)
  Search for HECTD2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
HECT Domain Containing E3 Ubiquitin Protein Ligase 21 2
HECT Domain Containing 21 2
HECT Domain-Containing Protein 22 3
Probable E3 Ubiquitin-Protein Ligase HECTD22
EC 6.3.2.-3

External Ids:    HGNC: 267361   Entrez Gene: 1432792   Ensembl: ENSG000001653387   UniProtKB: Q5U5R93   

Export aliases for HECTD2 gene to outside databases

Previous GC identifers: GC10P092835 GC10P086798


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for HECTD2 Gene:
HECTD2 (HECT domain containing E3 ubiquitin protein ligase 2) is a protein-coding gene. GO annotations related to this gene include ubiquitin-protein ligase activity. An important paralog of this gene is HERC3.

UniProtKB/Swiss-Prot: HECD2_HUMAN, Q5U5R9
Function: Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in
the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HECTD2 gene promoter:
         HOXA9   HOXA9B   Gfi-1   Evi-1   POU2F1   POU2F1a   Meis-1a   Meis-1   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHECTD2 promoter sequence
   Search Chromatin IP Primers for HECTD2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HECTD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q23.32   Ensembl cytogenetic band:  10q23.32   HGNC cytogenetic band: 10q23.32

HECTD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HECTD2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P093160:  view genomic region     (about GC identifiers)

Start:
93,170,096 bp from pter      End:
93,274,586 bp from pter
Size:
104,491 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HECD2_HUMAN, Q5U5R9 (See protein sequence)
Recommended Name: Probable E3 ubiquitin-protein ligase HECTD2  
Size: 776 amino acids; 88122 Da
Secondary accessions: Q5VZ97 Q5VZ98 Q5VZ99 Q8N1X7 Q8TCP5
Alternative splicing: 2 isoforms:  Q5U5R9-1   Q5U5R9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for HECTD2: NX_Q5U5R9

Explore proteomics data for HECTD2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys53
  • Modification sites at PhosphoSitePlus

  • See HECTD2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001271203.1  NP_775768.3  NP_877497.3  

    ENSEMBL proteins: 
     ENSP00000360746   ENSP00000298068   ENSP00000360731   ENSP00000401023   ENSP00000439687  

    HECTD2 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for HECTD2

     
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    Search eBioscience for ELISAs for HECTD2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR000569 HECT

    Graphical View of Domain Structure for InterPro Entry Q5U5R9

    ProtoNet protein and cluster: Q5U5R9

    1 Blocks protein domain: IPB000569 HECT domain (Ubiquitin-protein ligase)

    UniProtKB/Swiss-Prot: HECD2_HUMAN, Q5U5R9
    Similarity: Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain


    Find genes that share domains with HECTD2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HECD2_HUMAN, Q5U5R9
    Function: Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in
    the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity)

         Enzyme Number (IUBMB): EC 6.3.2.-1

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004842ubiquitin-protein ligase activity IBA--
         
    Find genes that share ontologies with HECTD2           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for HECTD2:
     Increased cell death HMECs cel  Increased cilium length after  

         1 MGI phenotypic allele for Hectd2 (no phenotypes)

    Find genes that share phenotypes with HECTD2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HECTD2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HECTD2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HECTD2
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    miRNA
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    miRTarBase miRNAs that target HECTD2:
    hsa-mir-221-3p (MIRT024205), hsa-mir-340-5p (MIRT019625), hsa-mir-335-5p (MIRT018117), hsa-mir-218-5p (MIRT024252)

    Block miRNA regulation of human, mouse, rat HECTD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HECTD2 (see all 26):
    hsa-miR-448 hsa-miR-202 hsa-miR-106a hsa-miR-548v hsa-miR-218 hsa-miR-221 hsa-miR-548a-3p hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidHECTD2 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HECTD2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3
    extracellular1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IBA--
    GO:0005737cytoplasm IBA--

    Find genes that share ontologies with HECTD2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    UniProtKB/Swiss-Prot: HECD2_HUMAN, Q5U5R9
    Pathway: Protein modification; protein ubiquitination

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HECTD2
    Interactions:

        Search GeneGlobe Interaction Network for HECTD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for HECTD2 (Q5U5R93 ENSP000002980684) via UniProtKB, MINT, STRING, and/or I2D (see all 23)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    PAPD5Q8NDF83I2D: score=2 
    ABCG2Q9UNQ03I2D: score=1 
    CHIAQ9BZP63I2D: score=1 
    FA2HQ7L5A83I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic process IBA--

    Find genes that share ontologies with HECTD2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HECTD2 (HECD2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HECTD2 gene (3 alternative transcripts): 
    NM_001284274.1  NM_173497.3  NM_182765.4  

    Unigene Cluster for HECTD2:

    HECT domain containing E3 ubiquitin protein ligase 2
    Hs.596096  [show with all ESTs]
    Unigene Representative Sequence: NM_182765
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371681(uc001khk.2) ENST00000298068(uc009xty.1) ENST00000498446
    ENST00000371667(uc001khn.1) ENST00000446394(uc001khl.2 uc010qnm.1 uc001khm.2)
    ENST00000536715
    miRNA
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    Block miRNA regulation of human, mouse, rat HECTD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HECTD2 (see all 26):
    hsa-miR-448 hsa-miR-202 hsa-miR-106a hsa-miR-548v hsa-miR-218 hsa-miR-221 hsa-miR-548a-3p hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidHECTD2 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector (see all 2): HECTD2 (NM_182765)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HECTD2
    Primer
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    OriGene qPCR primer pairs and template standards for HECTD2
    OriGene qSTAR qPCR primer pairs in human, mouse for HECTD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HECTD2
      QuantiTect SYBR Green Assays in human, mouse, rat HECTD2
      QuantiFast Probe-based Assays in human, mouse, rat HECTD2

    Additional mRNA sequence: 

    AF131793.1 AK094625.1 AK122629.1 AK295723.1 AL713675.1 BC040187.1 BX537856.1 

    8 DOTS entries:

    DT.95159826  DT.75100678  DT.40306043  DT.99955649  DT.410693  DT.100671974  DT.91948400  DT.92035613 

    Selected AceView cDNA sequences (see all 80):

    Z45654 BX097208 BC036487 Z42993 AI217197 AW771211 AI973069 AA405558 
    AI635346 AI682502 AA633619 AL713675 AA405548 AK122629 Z41325 AA447223 
    AI640842 AA744571 AL832073 AF131793 AI968210 NM_173497 BI544583 AI370615 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HECTD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    HECTD2 Expression
    About this image


    HECTD2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Spinal Cord (Nervous System)
             Oligodendrocyte progenitor cells
     
     Brain (Nervous System)
             Oligodendrocyte progenitor cells
     
     Oligodendrocytes (Nervous System)
             Oligodendrocyte progenitor cells
    HECTD2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HECTD2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.596096
        Custom PCR Arrays for HECTD2
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for HECTD2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hectd21 , 5 HECT domain containing 21, 5 89.15(n)1
    89.66(a)1
      19 (31.77 cM)5
    2260981  NM_001163471.11  NP_001156943.11 
     365546395 
    chicken
    (Gallus gallus)
    Aves HECTD21 HECT domain containing E3 ubiquitin protein ligase more 81.24(n)
    83.97(a)
      427031  XM_004942150.1  XP_004942207.1 
    lizard
    (Anolis carolinensis)
    Reptilia HECTD26
    HECT domain containing E3 ubiquitin protein ligase...
    74(a)
    1 ↔ 1
    GL343219.1(906792-960595)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia hectd21 HECT domain containing E3 ubiquitin protein ligase more 76.89(n)
    82.4(a)
      100127570  NM_001112937.1  NP_001106408.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hectd21 HECT domain containing 2 70.66(n)
    75.74(a)
      562999  XM_686363.5  XP_691455.5 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes HUL4(YJR036C)4 Protein with similarity to hect domain E3 ubiquitin-protein more   --   10(503391-500713) 853494  NP_012570.1 


    ENSEMBL Gene Tree for HECTD2 (if available)
    TreeFam Gene Tree for HECTD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HECTD2 gene
    HERC32  HERC62  RCCD12  HERC42  UBE3A2  HERC52  
    13 SIMAP similar genes for HECTD2 using alignment to 4 protein entries:     HECD2_HUMAN (see all proteins):
    DKFZp313O1018    UBE3A    DKFZp564G092    HERC3    HERC5    HUWE1
    NEDD4    HERC4    NEDD4L    DKFZp564H223    HECW1    SMURF2
    HECTD1

    Find genes that share paralogs with HECTD2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    1 SNPs for HECTD2    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs70815691,2,4
    ----see VAR_0268362 mis40--------

    HapMap Linkage Disequilibrium report for HECTD2 (93170096 - 93274586 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for HECTD2 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2189509CNV Deletion18987734
    esv2421381CNV Duplication20811451
    nsv7488CNV Insertion18451855
    nsv895891CNV Loss21882294
    dgv801n71CNV Loss21882294
    esv33149CNV Loss17666407
    nsv433413CNV Gain18776910
    esv1767604OTHER Inversion17803354
    nsv436654OTHER Inversion17901297
    esv1003018OTHER Inversion20482838

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HECTD2
    DNA2.0 Custom Variant and Variant Library Synthesis for HECTD2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease from the University of Copenhagen DISEASES database for HECTD2:
    Prion disease

    Find genes that share disorders with HECTD2           About GenesLikeMe

    Genetic Association Database (GAD): HECTD2
    Human Genome Epidemiology (HuGE) Navigator: HECTD2 (2 documents)

    Export disorders for HECTD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HECTD2 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with HECTD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    5. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 3 Yu W.... Gibbs R.A. (Genome Res. 1997)
    6. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (Anal. Biochem. 1996)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Absence of association between two HECTD2 polymorphisms and sporadic Creutzfeldt-Jakob disease. (PubMed id 21335971)1 Jeong B.H....Kim Y.S. (Dement Geriatr Cogn Disord 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 143279 HGNC: 26736 AceView: HECTD2 Ensembl:ENSG00000165338 euGenes: HUgn143279
    ECgene: HECTD2 H-InvDB: HECTD2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HECTD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HECTD2 gene:
    Search GeneIP for patents involving HECTD2

    GeneCards and IP:
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