Aliases for HECTD1 Gene
Aliases for HECTD1 Gene
External Ids for HECTD1 Gene
- HGNC: 20157
- Entrez Gene: 25831
- Ensembl: ENSG00000092148
- UniProtKB: Q9ULT8
Previous GeneCards Identifiers for HECTD1 Gene
- GC14M025356
- GC14M029559
- GC14M030639
- GC14M031569
- GC14M011686
Summaries for HECTD1 Gene
GeneCards Summary for HECTD1 Gene
HECTD1 (HECT Domain E3 Ubiquitin Protein Ligase 1) is a Protein Coding gene. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. GO annotations related to this gene include binding and ubiquitin-protein transferase activity. An important paralog of this gene is TRIP12.
UniProtKB/Swiss-Prot for HECTD1 Gene
-
Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HECTD1 Gene
Genomics for HECTD1 Gene
Regulatory Elements for HECTD1 Gene
Enhancers for HECTD1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around HECTD1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the HECTD1 gene promoter:
Regulatory Element Products
Genomic Location for HECTD1 Gene
- Chromosome:
- 14
- Start:
- 31,100,112 bp from pter
- End:
- 31,208,060 bp from pter
- Size:
- 107,949 bases
- Orientation:
- Minus strand
Genomic View for HECTD1 Gene
Genes around HECTD1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q12 by Ensembl
- 14q12 by Entrez Gene
- 14q12 by HGNC
HECTD1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HECTD1 Gene
Proteins for HECTD1 Gene
-
Protein details for HECTD1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9ULT8-HECD1_HUMAN
- Recommended name:
- E3 ubiquitin-protein ligase HECTD1
- Protein Accession:
- Q9ULT8
- D3DS86
- Q6P445
- Q86VJ1
- Q96F34
- Q9UFZ7
Protein attributes for HECTD1 Gene
- Size:
- 2610 amino acids
- Molecular mass:
- 289384 Da
- Quaternary structure:
-
- Interacts with IGSF1.
Protein Expression for HECTD1 Gene
Post-translational modifications for HECTD1 Gene
Other Protein References for HECTD1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for HECTD1
- Invitrogen Antibodies for HECTD1
- antibodies-online Antibodies for HECTD1: See all 26
- Search GeneTex for Antibodies for HECTD1
-
Santa Cruz Biotechnology (SCBT) Antibodies for HECTD1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HECTD1
- Origene Custom Protein Services for HECTD1
- Novus Biologicals proteins for HECTD1
- Search GeneTex for Proteins for HECTD1
Assay Products
No data available for DME Specific Peptides for HECTD1 Gene
Domains & Families for HECTD1 Gene
Gene Families for HECTD1 Gene
Protein Domains for HECTD1 Gene
Suggested Antigen Peptide Sequences for HECTD1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9ULT8- Family:
-
- Belongs to the UPL family. K-HECT subfamily.
Function for HECTD1 Gene
Molecular function for HECTD1 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.
- UniProtKB/Swiss-Prot Function:
- Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure.
Enzyme Numbers (IUBMB) for HECTD1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 12421765 |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for HECTD1 Gene
- MGI mutant phenotypes for HECTD1:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for HECTD1:
Animal Models for HECTD1 Gene
- MGI Knock Outs for HECTD1:
-
- Hectd1 tm1b(EUCOMM)Hmgu
Animal Model Products
-
Taconic Biosciences Mouse Models for HECTD1
-
ViGene Biosciences lentiviral particle packaged cDNA for HECTD1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HECTD1 gene
- Search ViGene Biosciences for HECTD1
CRISPR Products
-
OriGene CRISPR knockouts for HECTD1
-
Santa Cruz Biotechnology (SCBT) CRISPR for HECTD1
- GenScript: Design CRISPR guide RNA sequences for HECTD1
miRNA for HECTD1 Gene
- miRTarBase miRNAs that target HECTD1
-
- hsa-mir-210-3p (MIRT003177)
- hsa-mir-335-5p (MIRT018159)
- hsa-mir-30a-5p (MIRT028576)
- hsa-mir-21-5p (MIRT030921)
- hsa-mir-221-3p (MIRT046899)
- hsa-mir-142-3p (MIRT437603)
- hsa-mir-374a-5p (MIRT440517)
- hsa-mir-6073 (MIRT493635)
- hsa-mir-20b-3p (MIRT493636)
- hsa-mir-6514-5p (MIRT493637)
- hsa-mir-4802-5p (MIRT493638)
- hsa-mir-4280 (MIRT493639)
- hsa-mir-1183 (MIRT493640)
- hsa-mir-203a-3p (MIRT493641)
- hsa-mir-4668-5p (MIRT617232)
- hsa-mir-3613-3p (MIRT617233)
- hsa-mir-5002-5p (MIRT617234)
- hsa-mir-32-5p (MIRT727509)
- hsa-mir-92a-3p (MIRT727510)
- hsa-mir-92b-3p (MIRT727511)
miRNA Products
- Search ViGene Biosciences for HECTD1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HECTD1
- Browse OriGene Inhibitory RNA Products For HECTD1
-
ViGene Biosciences ready-to-package AAV shRNAs for HECTD1 gene
Clone Products
-
OriGene ORF clones in human for HECTD1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for HECTD1
Cell Line Products
-
Horizon Cell Lines for HECTD1
-
ViGene Biosciences adenoviral particle packaged cDNA for HECTD1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for HECTD1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HECTD1 gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HECTD1 Gene
Localization for HECTD1 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for HECTD1 Gene
Pathways & Interactions for HECTD1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Class I MHC mediated antigen processing and presentation | ||
| 2 | Innate Immune System |
.61
|
|
Pathways by source for HECTD1 Gene
4 Reactome pathways for HECTD1 Gene
UniProtKB/Swiss-Prot Q9ULT8-HECD1_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for HECTD1 Gene
Selected Interacting proteins:
Q9ULT8-HECD1_HUMAN
ENSP00000382269
for HECTD1 Gene via
MINT
STRING
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016567 | protein ubiquitination | IEA | -- |
No data available for SIGNOR curated interactions for HECTD1 Gene
Transcripts for HECTD1 Gene
mRNA/cDNA for HECTD1 Gene
- (11) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (307) Selected AceView cDNA sequences:
- (19) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for HECTD1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HECTD1
-
Santa Cruz Biotechnology (SCBT) CRISPR for HECTD1
- GenScript: Design CRISPR guide RNA sequences for HECTD1
miRNA Products
- Search ViGene Biosciences for HECTD1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HECTD1
- Browse OriGene Inhibitory RNA Products For HECTD1
-
ViGene Biosciences ready-to-package AAV shRNAs for HECTD1 gene
Clone Products
-
OriGene ORF clones in human for HECTD1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for HECTD1
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: |
| ExUns: | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22 | ^ | 23a | · | 23b | ^ | 24 | ^ | 25 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||||
| SP10: |
Expression for HECTD1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for HECTD1 Gene
This gene is overexpressed in Muscle - Skeletal (x5.8).
This gene is overexpressed in Cervix (25.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HECTD1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of HECTD1 Gene:
HECTD1SOURCE GeneReport for Unigene cluster for HECTD1 Gene:
Hs.708017Evidence on tissue expression from TISSUES for HECTD1 Gene
- Nervous system(4.8)
- Liver(4.4)
- Muscle(4.4)
- Kidney(2.2)
Primer Products
-
OriGene qPCR primer pairs for HECTD1
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HECTD1 Gene
Orthologs for HECTD1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HECTD1 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | HECTD1 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | HECTD1 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | HECTD1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | HECTD1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Hectd1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hectd1 34 |
|
||
| chicken (Gallus gallus) |
Aves | HECTD1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | HECTD1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hectd1 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.19091 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | hectd1 34 34 35 |
|
||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.1384 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG5604 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP009511 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | hecd-1 34 35 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | UFD4 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.1003 35 |
|
OneToOne |
- Species where no ortholog for HECTD1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for HECTD1 Gene
(11) SIMAP similar genes for HECTD1 Gene using alignment to 8 proteins:
Variants for HECTD1 Gene
| SNP ID | Clin | Chr 14 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000008287 | -- | 31,118,999(+) | TCTTT(C/T)TAGAG | intron-variant | |
| rs1000010869 | -- | 31,160,918(+) | TCCCA(C/T)CTCAG | intron-variant | |
| rs1000058581 | -- | 31,202,025(+) | CTCAC(A/G)CCTGT | intron-variant | |
| rs1000095089 | -- | 31,133,669(+) | GTTGC(A/T)GTTGA | nc-transcript-variant, reference, synonymous-codon | |
| rs1000110630 | -- | 31,126,395(+) | GATTA(C/T)AGCAT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv33189 | CNV | loss | 17666407 |
| esv3584215 | CNV | gain | 25503493 |
| esv3892495 | CNV | gain | 25118596 |
| nsv1043033 | CNV | gain | 25217958 |
| nsv1049063 | CNV | gain | 25217958 |
| nsv1050054 | CNV | gain | 25217958 |
| nsv1234 | CNV | insertion | 18451855 |
| nsv832763 | CNV | loss | 17160897 |
| nsv976325 | CNV | duplication | 23825009 |
| nsv983810 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
0.392% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.23;
70.02% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for HECTD1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HECTD1 Gene
Disorders for HECTD1 Gene
Relevant External Links for HECTD1
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- HECTD1
No disorders were found for HECTD1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HECTD1 Gene
Publications for HECTD1 Gene
- Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PMID: 10574461) Hirosawa M. … Ohara O. (DNA Res. 1999) 2 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. (PMID: 12421765) Nakayama M. … Ohara O. (Genome Res. 2002) 3 4 64
- HECTD1 controls the protein level of IQGAP1 to regulate the dynamics of adhesive structures. (PMID: 28073378) Shen X. … Zhang H. (Cell Commun. Signal 2017) 3 64
- System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. (PMID: 26949039) Zhang W. … Sidhu S.S. (Mol. Cell 2016) 3 64
Products for HECTD1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HECTD1
- Origene Custom Protein Services for HECTD1
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for HECTD1
- Browse OriGene Inhibitory RNA Products For HECTD1
- OriGene qPCR primer pairs for HECTD1
- OriGene CRISPR knockouts for HECTD1
- OriGene ORF clones in human for HECTD1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HECTD1
- GenScript: Next-day shipping cDNA ORF clone for HECTD1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for HECTD1
- GenScript Custom Assay Services for HECTD1
- GenScript Custom overexpressing Cell Line Services for HECTD1
- GenScript: Design CRISPR guide RNA sequences for HECTD1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for HECTD1
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for HECTD1
- Novus Biologicals proteins for HECTD1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for HECTD1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Addgene plasmids for HECTD1
- Search GeneTex for Antibodies for HECTD1
- Search GeneTex for Proteins for HECTD1
- ViGene Biosciences adenoviral particle packaged cDNA for HECTD1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for HECTD1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for HECTD1 gene
- Search ViGene Biosciences for HECTD1
- Santa Cruz Biotechnology (SCBT) Antibodies for HECTD1
- Search Santa Cruz Biotechnology (SCBT) for HECTD1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HECTD1
- Horizon Cell Lines for HECTD1
- Cyagen custom Knockout/knockin (KOKI) mouse models for HECTD1
- VectorBuilder custom plasmid, inducible vectors for HECTD1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HECTD1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for HECTD1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer