Aliases for HEBP2 Gene
External Ids for HEBP2 Gene
Previous HGNC Symbols for HEBP2 Gene
Previous GeneCards Identifiers for HEBP2 Gene
The protein encoded by this gene is found predominately in the cytoplasm, where it plays a role in the collapse of mitochondrial membrane potential (MMP) prior to necrotic cell death. The encoded protein enhances outer and inner mitochondrial membrane permeabilization, especially under conditions of oxidative stress. [provided by RefSeq, May 2016]
GeneCards Summary for HEBP2 Gene
HEBP2 (Heme Binding Protein 2) is a Protein Coding gene. An important paralog of this gene is HEBP1.
UniProtKB/Swiss-Prot for HEBP2 Gene
Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions. Does not bind hemin.