External Ids for HEBP1 Gene
Previous GeneCards Identifiers for HEBP1 Gene
The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008]
GeneCards Summary for HEBP1 Gene
HEBP1 (Heme Binding Protein 1) is a Protein Coding gene. Diseases associated with HEBP1 include teeth hard tissue disease. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. GO annotations related to this gene include heme binding. An important paralog of this gene is HEBP2.
UniProtKB/Swiss-Prot for HEBP1 Gene
May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities.