Aliases for HEBP1 Gene
External Ids for HEBP1 Gene
Previous GeneCards Identifiers for HEBP1 Gene
The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008]
GeneCards Summary for HEBP1 Gene
HEBP1 (Heme Binding Protein 1) is a Protein Coding gene. Diseases associated with HEBP1 include dental enamel hypoplasia and ankylosis. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include heme binding. An important paralog of this gene is HEBP2.
UniProtKB/Swiss-Prot for HEBP1 Gene
May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities.