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Aliases for HEATR9 Gene

Aliases for HEATR9 Gene

  • HEAT Repeat Containing 9 2 3 5
  • HEAT Repeat-Containing Protein 9 3 4
  • C17orf66 3 4
  • Chromosome 17 Open Reading Frame 66 2

External Ids for HEATR9 Gene

Previous HGNC Symbols for HEATR9 Gene

  • C17orf66

Previous GeneCards Identifiers for HEATR9 Gene

  • GC17M034182

Summaries for HEATR9 Gene

GeneCards Summary for HEATR9 Gene

HEATR9 (HEAT Repeat Containing 9) is a Protein Coding gene. GO annotations related to this gene include binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HEATR9 Gene

Genomics for HEATR9 Gene

Genomic Location for HEATR9 Gene

Chromosome:
17
Start:
35,854,946 bp from pter
End:
35,868,891 bp from pter
Size:
13,946 bases
Orientation:
Minus strand

Genomic View for HEATR9 Gene

Genes around HEATR9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HEATR9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HEATR9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HEATR9 Gene

No data available for Regulatory Elements for HEATR9 Gene

Proteins for HEATR9 Gene

  • Protein details for HEATR9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2RTY3-HEAT9_HUMAN
    Recommended name:
    Protein HEATR9
    Protein Accession:
    A2RTY3
    Secondary Accessions:
    • B4DX21
    • B4DXA4
    • B4DXF0
    • Q8N4R4
    • Q96M46

    Protein attributes for HEATR9 Gene

    Size:
    570 amino acids
    Molecular mass:
    65681 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for HEATR9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for HEATR9 Gene

Proteomics data for HEATR9 Gene at MOPED

Post-translational modifications for HEATR9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for HEATR9 Gene

No data available for DME Specific Peptides for HEATR9 Gene

Domains & Families for HEATR9 Gene

Protein Domains for HEATR9 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HEATR9: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HEATR9 Gene

Function for HEATR9 Gene

Phenotypes for HEATR9 Gene

genes like me logo Genes that share phenotypes with HEATR9: view

Animal Model Products

miRNA for HEATR9 Gene

miRTarBase miRNAs that target HEATR9

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HEATR9 Gene

Localization for HEATR9 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HEATR9 Gene

Pathways & Interactions for HEATR9 Gene

SuperPathways for HEATR9 Gene

No Data Available

Interacting Proteins for HEATR9 Gene

Gene Ontology (GO) - Biological Process for HEATR9 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HEATR9 Gene

Drugs & Compounds for HEATR9 Gene

No Compound Related Data Available

Transcripts for HEATR9 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for HEATR9 Gene

No ASD Table

Relevant External Links for HEATR9 Gene

GeneLoc Exon Structure for
HEATR9
ECgene alternative splicing isoforms for
HEATR9

Expression for HEATR9 Gene

mRNA expression in normal human tissues for HEATR9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for HEATR9 Gene

This gene is overexpressed in Testis (x35.4) and Whole Blood (x5.4).

Protein differential expression in normal tissues from HIPED for HEATR9 Gene

This gene is overexpressed in Bone marrow stromal cell (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for HEATR9 Gene



genes like me logo Genes that share expression patterns with HEATR9: view

Protein tissue co-expression partners for HEATR9 Gene

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for HEATR9 Gene

Orthologs for HEATR9 Gene

This gene was present in the common ancestor of mammals.

Orthologs for HEATR9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C19H17orf66 35
  • 79.51 (n)
  • 70.87 (a)
mouse
(Mus musculus)
Mammalia Gm11435 35
  • 75.7 (n)
  • 62.18 (a)
Heatr9 16
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf66 35
  • 98.07 (n)
  • 96.3 (a)
rat
(Rattus norvegicus)
Mammalia RGD1559875 35
  • 75.52 (n)
  • 63.1 (a)
Species with no ortholog for HEATR9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for HEATR9 Gene

ENSEMBL:
Gene Tree for HEATR9 (if available)
TreeFam:
Gene Tree for HEATR9 (if available)

Paralogs for HEATR9 Gene

No data available for Paralogs for HEATR9 Gene

Variants for HEATR9 Gene

Sequence variations from dbSNP and Humsavar for HEATR9 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs2306630 - 35,855,337(-) TCTCT(C/T)TGTAT nc-transcript-variant, reference, missense
VAR_035685 A breast cancer sample
rs2306629 -- 35,855,906(-) TGCAG(C/T)GGTTC intron-variant
rs2291299 -- 35,864,402(-) TGGGG(A/G)TGGTA intron-variant
rs4796118 -- 35,858,804(+) TCCAC(C/T)ACCAG intron-variant

Variation tolerance for HEATR9 Gene

Residual Variation Intolerance Score: 96.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.80; 66.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for HEATR9 Gene

HapMap Linkage Disequilibrium report
HEATR9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for HEATR9 Gene

Disorders for HEATR9 Gene

Relevant External Links for HEATR9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HEATR9

No disorders were found for HEATR9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HEATR9 Gene

Publications for HEATR9 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. New genetic associations detected in a host response study to hepatitis B vaccine. (PMID: 20237496) Davila S. … Seielstad M. (Genes Immun. 2010) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for HEATR9 Gene

Sources for HEATR9 Gene

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