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HEATR6 Gene

protein-coding   GIFtS: 48
GCID: GC17M058120

HEAT Repeat Containing 6

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
HEAT Repeat Containing 61 2
Amplified In Breast Cancer 11 2
Amplified In Breast Cancer Protein 12 3
ABC12 3
HEAT Repeat-Containing Protein 62

External Ids:    HGNC: 240761   Entrez Gene: 638972   Ensembl: ENSG000000680977   UniProtKB: Q6AI083   

Export aliases for HEATR6 gene to outside databases

Previous GC identifers: GC17M055476 GC17M053492


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for HEATR6 Gene:
HEATR6 (HEAT repeat containing 6) is a protein-coding gene. Diseases associated with HEATR6 include breast cancer, and malaria.

UniProtKB/Swiss-Prot: HEAT6_HUMAN, Q6AI08
Function: Amplification-dependent oncogene




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HEATR6 gene promoter:
         HOXA9   HOXA9B   ISGF-3   Lmo2   STAT5A   HOXA5   IRF-7A   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHEATR6 promoter sequence
   Search Chromatin IP Primers for HEATR6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HEATR6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q23.1   Ensembl cytogenetic band:  17q23.1   HGNC cytogenetic band: 17q23.2

HEATR6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HEATR6 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M058120:  view genomic region     (about GC identifiers)

Start:
58,120,552 bp from pter      End:
58,156,292 bp from pter
Size:
35,741 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: HEAT6_HUMAN, Q6AI08 (See protein sequence)
Recommended Name: HEAT repeat-containing protein 6  
Size: 1181 amino acids; 128781 Da
Miscellaneous: 17q23 region is one of the most commonly amplified regions in breast cancer and therefore may
harbor genes important for breast cancer development and progression
Sequence caution: Sequence=AAL83912.1; Type=Erroneous initiation; Sequence=BAB15229.1; Type=Erroneous initiation;
Sequence=BAB15348.1; Type=Erroneous initiation;
Secondary accessions: B3KXP3 Q6MZX1 Q6MZY2 Q8TDM9 Q9H6B3 Q9H6M7

Explore the universe of human proteins at neXtProt for HEATR6: NX_Q6AI08

Explore proteomics data for HEATR6 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HEATR6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_071353.4  
    ENSEMBL proteins: 
     ENSP00000184956   ENSP00000464927   ENSP00000466192   ENSP00000465540   ENSP00000465986  
     ENSP00000465595   ENSP00000465429   ENSP00000468810   ENSP00000465817  

    HEATR6 Human Recombinant Protein Products:

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    Novus Biologicals HEATR6 Lysate
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    Browse Proteins at Cloud-Clone Corp.

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    HEATR6 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR011989 ARM-like
     IPR025283 DUF4042
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q6AI08

    ProtoNet protein and cluster: Q6AI08

    UniProtKB/Swiss-Prot: HEAT6_HUMAN, Q6AI08
    Similarity: Contains 4 HEAT repeats


    HEATR6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HEAT6_HUMAN, Q6AI08
    Function: Amplification-dependent oncogene

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    HEATR6 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for HEATR6:
     Increased G2M DNA content, inc 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HEATR6
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HEATR6

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HEATR6
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HEATR6

    miRNA
    Products:
        
    miRTarBase miRNAs that target HEATR6:
    hsa-mir-193b-3p (MIRT016557), hsa-mir-615-3p (MIRT039759), hsa-mir-92a-3p (MIRT049537)

    Block miRNA regulation of human, mouse, rat HEATR6 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate HEATR6:
    hsa-miR-1233 hsa-miR-3672
    SwitchGear 3'UTR luciferase reporter plasmidHEATR6 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HEATR6

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    GenScript: all cDNA clones in your preferred vector: HEATR6 (NM_022070)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HEATR6

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HEATR6


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    extracellular1
    golgi apparatus1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HEATR6
    Interactions:

        Search GeneGlobe Interaction Network for HEATR6

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5 Interacting proteins for HEATR6 (Q6AI082, 3 ENSP000001849564) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNFRSF1BP203332, 3MINT-49430 I2D: score=2 
    MYCP011063I2D: score=2 
    DDA1Q9BW613I2D: score=1 
    PTPN11Q061243I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HEATR6 (HEAT6)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HEATR6 gene: 
    NM_022070.4  

    Unigene Cluster for HEATR6:

    HEAT repeat containing 6
    Hs.591183  [show with all ESTs]
    Unigene Representative Sequence: BX640831
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000184956(uc010ddk.1 uc010wos.1 uc002iyk.1) ENST00000585976
    ENST00000587003 ENST00000587314 ENST00000591683 ENST00000590587 ENST00000593228
    ENST00000593097 ENST00000592664 ENST00000591074 ENST00000585712
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HEATR6 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate HEATR6:
    hsa-miR-1233 hsa-miR-3672
    SwitchGear 3'UTR luciferase reporter plasmidHEATR6 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for HEATR6
    Predesigned siRNA for gene silencing in human, mouse, rat HEATR6
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    OriGene clones in human, mouse for HEATR6 (see all 6)
    OriGene ORF clones in mouse, rat for HEATR6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HEATR6 (NM_022070)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HEATR6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HEATR6
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for HEATR6
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HEATR6
      QuantiTect SYBR Green Assays in human, mouse, rat HEATR6
      QuantiFast Probe-based Assays in human, mouse, rat HEATR6

    Additional mRNA sequence: 

    AF349752.1 AK025740.1 AK026070.1 AK127708.1 AK314655.1 BC119771.1 BC119813.1 BX640819.1 
    BX640831.1 CR627418.1 

    5 DOTS entries:

    DT.412773  DT.95357181  DT.100647616  DT.120923685  DT.205482 

    Selected AceView cDNA sequences (see all 117):

    AA910077 Z38816 CA843555 CB305526 AI290042 BF223187 BM547348 AI041856 
    BI091646 BU187337 BM713511 AI672470 AI127144 BM709661 CA843310 BU624591 
    AI497780 BU957457 AI146670 AI342465 AA670100 BU739541 AA133790 AI561172 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for HEATR6 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a ·
    SP1:                                -     -     -                                                                                                               
    SP2:                                      -     -                                                                                                               
    SP3:                                -     -                                                                                                                     
    SP4:                                -     -     -     -     -                                                                                                   
    SP5:                                                                                                                                                            

    ExUns: 19b ^ 20 ^ 21a · 21b ^ 22a · 22b
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:              -                     


    ECgene alternative splicing isoforms for HEATR6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HEATR6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCAGGGTTG
    HEATR6 Expression
    About this image

    HEATR6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HEATR6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591183

    UniProtKB/Swiss-Prot: HEAT6_HUMAN, Q6AI08
    Tissue specificity: Amplified in breast cancer cell lines MCF-7 and BT-474

        Custom PCR Arrays for HEATR6
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HEATR6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for HEATR6 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Heatr61 , 5 HEAT repeat containing 61, 5 82.73(n)1
    83.57(a)1
      11 (51.23 cM)5
    2170261  NM_145432.31  NP_663407.21 
     837536965 
    chicken
    (Gallus gallus)
    Aves HEATR61 HEAT repeat containing 6 73.11(n)
    73.85(a)
      417661  XM_415906.4  XP_415906.3 
    lizard
    (Anolis carolinensis)
    Reptilia HEATR66
    HEAT repeat containing 6
    62(a)
    1 ↔ 1
    GL344172.1(50683-67404)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC539882 hypothetical protein MGC53988 74.84(n)    BC043967.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1723591 zgc:172359 59.34(n)
    56.85(a)
      567838  NM_001114313.1  NP_001107785.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG169891 CG16989 43.96(n)
    34.98(a)
      31026  NM_130504.2  NP_569860.2 


    ENSEMBL Gene Tree for HEATR6 (if available)
    TreeFam Gene Tree for HEATR6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HEATR6 gene
    10 SIMAP similar genes for HEATR6 using alignment to 10 protein entries:     HEAT6_HUMAN (see all proteins):
    FRG1    ZNF114    DYNC2LI1    SEPSECS    TUBA1C    SH2B3
    C14orf105    EEF1E1    ZNF799    CALCOCO2

    HEATR6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HEATR6 (see all 647)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1116913351,2
    C,F--58120405(+) GGCACC/TGTCAG 1 -- ds50011Minor allele frequency- T:0.50WA 2
    rs1471453001,2
    --58120427(+) CTGTGC/TGGCTG 1 -- ds50010--------
    rs1857165031,2
    --58122515(+) AAGGCA/GGATAA 1 -- int10--------
    rs746647821,2
    F--58122548(+) AAAAGG/CTCACC 1 -- int11Minor allele frequency- C:0.02WA 118
    rs80679091,2
    C,F,A,H--58122627(+) TGGACG/ACTCTG 1 -- int118Minor allele frequency- A:0.11NS EA NA CSA WA 2342
    rs1145386761,2
    F--58122667(+) CCTCAC/TTTGAT 1 -- int11Minor allele frequency- T:0.02WA 118
    rs1410619111,2
    --58122673(+) TTGATA/GTGTGC 1 -- int10--------
    rs1149812371,2
    C--58122737(+) ATAAAC/GCGAAC 1 -- int10--------
    rs1388759351,2
    --58122738(+) TAAAGC/TGAACG 1 -- int10--------
    rs65039421,2
    C,F,A,H--58122739(+) AAAGCG/AAACGC 1 -- int118Minor allele frequency- A:0.10NS EA NA CSA WA 2338

    HapMap Linkage Disequilibrium report for HEATR6 (58120552 - 58156292 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for HEATR6:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2653138CNV Deletion19546169
    nsv833504CNV Gain17160897
    nsv428348CNV Gain18775914
    nsv471702CNV Gain15918152
    nsv833502CNV Gain17160897
    dgv996e1CNV Complex17122850
    nsv7295OTHER Inversion18451855
    nsv499622OTHER Inversion21111241

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HEATR6
    DNA2.0 Custom Variant and Variant Library Synthesis for HEATR6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for HEATR6:    
    About MalaCards
    breast cancer    malaria

    1 disease from the University of Copenhagen DISEASES database for HEATR6:
    Breast cancer

    HEATR6 for disorders           About GeneDecksing


    Export disorders for HEATR6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HEATR6 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with HEATR6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The 17q23 amplicon and breast cancer. (PubMed id 12755490)1, 3 Sinclair C.S....Couch F.J. (Breast Cancer Res. Treat. 2003)
    2. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    3. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    6. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    7. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    8. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. Large-scale proteomics analysis of the human kinome. (PubMed id 19369195)2 Oppermann F.S.... Daub H. (Mol. Cell. Proteomics 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 63897 HGNC: 24076 AceView: ABC1 Ensembl:ENSG00000068097 euGenes: HUgn63897
    ECgene: HEATR6 H-InvDB: HEATR6

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HEATR6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    Patent Information for HEATR6 gene:
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    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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