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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HEATR5B Gene

protein-coding   GIFtS: 47
GCID: GC02M037195

HEAT Repeat Containing 5B

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
HEAT Repeat Containing 5B1 2
HEAT Repeat-Containing Protein 5B2
KIAA14143

External Ids:    HGNC: 292731   Entrez Gene: 544972   Ensembl: ENSG000000088697   UniProtKB: Q9P2D33   

Export aliases for HEATR5B gene to outside databases

Previous GC identifers: GC02M037061 GC02M036949


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for HEATR5B Gene: 
HEATR5B (HEAT repeat containing 5B) is a protein-coding gene. Diseases associated with HEATR5B include myocardial infarction. An important paralog of this gene is HEATR5A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_022184.15  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HEATR5B gene promoter:
         HOXA9B   HOXA9   FOXO3   Ik-3   Egr-4   Meis-1b   GATA-2   HSF2   IRF-7A   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHEATR5B promoter sequence
   Search SABiosciences Chromatin IP Primers for HEATR5B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HEATR5B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p22.2   Ensembl cytogenetic band:  2p22.2   HGNC cytogenetic band: 2p22.2

HEATR5B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HEATR5B gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M037195:  view genomic region     (about GC identifiers)

Start:
37,195,526 bp from pter      End:
37,311,485 bp from pter
Size:
115,960 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HTR5B_HUMAN, Q9P2D3 (See protein sequence)
Recommended Name: HEAT repeat-containing protein 5B  
Size: 2071 amino acids; 224302 Da
Sequence caution: Sequence=BAA91733.1; Type=Erroneous initiation;
Secondary accessions: B5MDU8 Q7Z3B2 Q9NVL7
Alternative splicing: 3 isoforms:  Q9P2D3-1   Q9P2D3-2   Q9P2D3-3   

Explore the universe of human proteins at neXtProt for HEATR5B: NX_Q9P2D3

Explore proteomics data for HEATR5B at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9P2D3

  • HEATR5B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HEATR5B Protein Expression
    REFSEQ proteins: NP_061897.1  
    ENSEMBL proteins: 
     ENSP00000408222   ENSP00000233099   ENSP00000346531  

    Human Recombinant Protein Products for HEATR5B: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR011989 ARM-like
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q9P2D3

    ProtoNet protein and cluster: Q9P2D3

    1 Blocks protein domain: IPB000357 HEAT repeat

    UniProtKB/Swiss-Prot: HTR5B_HUMAN, Q9P2D3
    Similarity: Belongs to the HEATR5 family
    Similarity: Contains 3 HEAT repeats


    HEATR5B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
         
    HEATR5B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for HEATR5B:
     Decreased circadian period len 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for HEATR5B 
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate HEATR5B:
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    SwitchGear 3'UTR luciferase reporter plasmidHEATR5B 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HEATR5B


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HEATR5B

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for HEATR5B (ENSP000002330994) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HEATR5B (HTR5B)

    Search CenterWatch for drugs/clinical trials and news about HEATR5B / HTR5B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HEATR5B gene: 
    NM_019024.1  

    Unigene Cluster for HEATR5B:

    HEAT repeat containing 5B
    Hs.744084  [show with all ESTs]
    Unigene Representative Sequence: NM_019024
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000425467 ENST00000233099(uc002rpp.1) ENST00000471051(uc002rpq.4)
    ENST00000467978 ENST00000478810 ENST00000354531(uc010ezy.1)
    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate HEATR5B:
    hsa-miR-24
    SwitchGear 3'UTR luciferase reporter plasmidHEATR5B 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HEATR5B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HEATR5B

    Additional mRNA sequence: 

    AB037835.1 AK001513.1 AK022179.1 AK026928.1 AK093937.1 AK096637.1 AL832880.1 BC031035.1 
    BC085607.1 BC150605.1 BX538008.1 BX648805.1 

    12 DOTS entries:

    DT.95090339  DT.92427288  DT.445133  DT.99927813  DT.99934593  DT.100738250  DT.92005225  DT.91841263 
    DT.95325766  DT.75148173  DT.75163930  DT.99966318 

    24/134 AceView cDNA sequences (see all 134):

    AW338205 BX503920 Z41197 BX280418 AA236640 AK096637 CA432330 F09206 
    BM474864 BQ101046 AL832880 AI432311 F11546 CR618236 AW752588 AW847728 
    AB037835 AK026928 F11545 AA779076 C18350 Z45504 BQ086364 CD654038 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for HEATR5B (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^ 21 ^ 22 ^
    SP1:                                                                                            -                                         -                     
    SP2:                                                                                            -                                         -                     
    SP3:                                                                                                                                      -                     
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b ^ 29a · 29b ^ 30 ^ 31 ^ 32 ^ 33a · 33b ^ 34 ^ 35 ^ 36a · 36b ^ 37
    SP1:  -                                                                                                               
    SP2:  -                                                                                                               
    SP3:  -                                                                                                               
    SP4:                                                                          -     -                                 
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for HEATR5B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HEATR5B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    HEATR5B Expression
    About this image


    See HEATR5B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HEATR5B

    SOURCE GeneReport for Unigene cluster: Hs.744084
        SABiosciences Custom PCR Arrays for HEATR5B
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for HEATR5B gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Heatr5b1 , 5 HEAT repeat containing 5B1, 5 86.97(n)1
    95.89(a)1
      17 (49.54 cM)5
    3204731  NM_001081179.11  NP_001074648.11 
     787529065 
    chicken
    (Gallus gallus)
    Aves HEATR5B1 HEAT repeat containing 5B 81.26(n)
    93.14(a)
      421469  XM_419518.3  XP_419518.2 
    lizard
    (Anolis carolinensis)
    Reptilia HEATR5B6
    Uncharacterized protein
    90(a)
    1 ↔ 1
    1(232599124-232656645)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.197542 Xenopus laevis transcribed sequence with weak similarity more 79.7(n)    BG486892.1 
    zebrafish
    (Danio rerio)
    Actinopterygii heatr5b1 HEAT repeat containing 5B 71.08(n)
    85.78(a)
      571772  XM_001920861.2  XP_001920896.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG27471 CG2747 53.62(n)
    52.74(a)
      40950  NM_141504.2  NP_649761.2 
    worm
    (Caenorhabditis elegans)
    Secernentea C13F10.41 Protein C13F10.4 48.25(n)
    39.85(a)
      179109  NM_072427.3  NP_504828.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes LAA16
    AP-1 accessory protein; colocalizes with clathrin ...
    15(a)
    1 → many
    X(41389-47433)


    ENSEMBL Gene Tree for HEATR5B (if available)
    TreeFam Gene Tree for HEATR5B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HEATR5B gene
    HEATR5A2  
    1 SIMAP similar gene for HEATR5B using alignment to 3 protein entries:     HTR5B_HUMAN (see all proteins):
    HEATR5A

    HEATR5B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2293 SNPs in HEATR5B are shown (see all 2293)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs30807951,2
    C--37104424(+) CAAAC-/TCAACAT 1 -- int10--------
    rs751932671,2
    F--37207692(+) GACTTG/ACTTTT 1 -- ds50011Minor allele frequency- A:0.10WA 118
    rs1855315251,2
    --37207796(+) TATTTC/TGTACG 1 -- ds50010--------
    rs1453612611,2
    --37207800(+) TCGTAC/TGGTAA 1 -- ds50010--------
    rs1904567111,2
    --37207801(+) CGTACA/GGTAAA 1 -- ds50010--------
    rs1814490401,2
    --37207815(+) CCCACC/TACATG 1 -- ds50010--------
    rs1154434481,2
    F--37207910(+) TTCAAT/CAAATA 1 -- ds50011Minor allele frequency- C:0.01NA 120
    rs793261091,2
    F--37208293(+) CCCATT/ATTTTT 1 -- ut311Minor allele frequency- A:0.01EA 120
    rs1859858151,2
    --37208324(+) CTGCCC/TGACTA 1 -- ut310--------
    rs1900561861,2
    --37208404(+) CAAAAC/GAGAAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for HEATR5B (37195526 - 37311485 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for HEATR5B:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2719928CNV Deletion23290073
    esv2719926CNV Deletion23290073
    esv2719930CNV Deletion23290073
    esv2719927CNV Deletion23290073
    nsv873879CNV Loss21882294
    nsv456363CNV Gain19166990
    nsv428395CNV Gain18775914

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing HEATR5B
    DNA2.0 Custom Variant and Variant Library Synthesis for HEATR5B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for HEATR5B:    About MalaCards
    myocardial infarction    


    HEATR5B for disorders           About GeneDecksing

    Genetic Association Database (GAD): HEATR5B
    Human Genome Epidemiology (HuGE) Navigator: HEATR5B (3 documents)

    Export disorders for HEATR5B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HEATR5B gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with HEATR5B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2, 3 Nagase T.... Ohara O. (2000)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Common variants in 22 loci are associated with QRS du ration and cardiac ventricular conduction. (PubMed id 21076409)1, 4 Sotoodehnia N....Arking D.E. (2010)
    4. Gene variants associated with ischemic stroke: the cardiovascular health study. (PubMed id 19023099)1, 4 Luke M.M....Psaty B.M. (2009)
    5. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. (PubMed id 17975119)1, 4 Shiffman D....Psaty B.M. (2008)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    10. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54497 HGNC: 29273 AceView: KIAA1414 Ensembl:ENSG00000008869 euGenes: HUgn54497
    ECgene: HEATR5B H-InvDB: HEATR5B

    (According to HUGE)
    About This Section
    HUGE: KIAA1414

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HEATR5B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HEATR5B gene:
    Search GeneIP for patents involving HEATR5B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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