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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HEATR1 Gene

protein-coding   GIFtS: 54
GCID: GC01M236712

HEAT Repeat Containing 1

  Search for HEATR1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
HEAT Repeat Containing 11 2     Small Subunit (SSU) Processome Component1
UTP101 2     HEAT Repeat-Containing Protein 12
Protein BAP282 3     UTP10, Small Subunit (SSU) Processome Component, Homolog2
BAP282 3     EC 4.1.1.318
Homolog (Yeast)1     EC 6.3.4.48

External Ids:    HGNC: 255171   Entrez Gene: 551272   Ensembl: ENSG000001192857   UniProtKB: Q9H5833   

Export aliases for HEATR1 gene to outside databases

Previous GC identifers: GC01M233039 GC01M234778 GC01M207169


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for HEATR1 Gene: 
HEATR1 (HEAT repeat containing 1) is a protein-coding gene. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: HEAT1_HUMAN, Q9H583
Function: Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By
similarity)

Gene Wiki entry for HEATR1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_167186.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HEATR1 gene promoter:
         Nkx3-1   GATA-3   ATF-2   STAT5A   Tal-1beta   Evi-1   E47   Nkx6-1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHEATR1 promoter sequence
   Search SABiosciences Chromatin IP Primers for HEATR1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HEATR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q43   Ensembl cytogenetic band:  1q43   HGNC cytogenetic band: 1q43

HEATR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HEATR1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M236712:  view genomic region     (about GC identifiers)

Start:
236,712,305 bp from pter      End:
236,767,841 bp from pter
Size:
55,537 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HEAT1_HUMAN, Q9H583 (See protein sequence)
Recommended Name: HEAT repeat-containing protein 1  
Size: 2144 amino acids; 242370 Da
Subcellular location: Nucleus, nucleolus
Sequence caution: Sequence=BAA91564.1; Type=Erroneous initiation;
Secondary accessions: Q5T3Q8 Q6P197 Q9NW23

Explore the universe of human proteins at neXtProt for HEATR1: NX_Q9H583

Explore proteomics data for HEATR1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H583

  • 2 DME Specific Peptides for HEATR1 (Q9H583)
     FLAELME  ALQKVVE 

    HEATR1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HEATR1 Protein Expression
    REFSEQ proteins: NP_060542.4  
    ENSEMBL proteins: 
     ENSP00000355541   ENSP00000355540   ENSP00000355538  

    Human Recombinant Protein Products for HEATR1: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HEATR1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005739mitochondrion IDA--
    GO:0030529ribonucleoprotein complex IEA--

    HEATR1 for ontologies           About GeneDecksing



    HEATR1 Antibody Products: 
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    Cloud-Clone Corp. ELISAs for HEATR1 
    Cloud-Clone Corp. CLIAs for HEATR1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR022125 U3snoRNP10
     IPR011989 ARM-like
     IPR012954 BP28_C_dom
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q9H583

    ProtoNet protein and cluster: Q9H583

    2 Blocks protein domains:
    IPB000357 HEAT repeat
    IPB012954 BP28


    UniProtKB/Swiss-Prot: HEAT1_HUMAN, Q9H583
    Similarity: Belongs to the HEATR1/UTP10 family
    Similarity: Contains 1 HEAT repeat


    HEATR1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HEAT1_HUMAN, Q9H583
    Function: Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By
    similarity)

         Enzyme Numbers (IUBMB): EC 6.3.4.42 EC 4.1.1.312

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding IPI--
         
    HEATR1 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for HEATR1:
     Decreased p24 protein expressi  Decreased viability of wild-ty  Nuclear 40S maturation defects  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for HEATR1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HEATR1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HEATR1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HEATR1 

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    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate HEATR1 (see all 25):
    hsa-miR-3910 hsa-miR-548j hsa-miR-4254 hsa-miR-548i hsa-miR-649 hsa-miR-124 hsa-miR-506 hsa-miR-548d-5p
    SwitchGear 3'UTR luciferase reporter plasmidHEATR1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HEATR1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for HEATR1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for HEATR1):
        Ribosome biogenesis in eukaryotes


    HEATR1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HEATR1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/171 Interacting proteins for HEATR1 (Q9H5831, 2, 3 ENSP000003555414) via UniProtKB, MINT, STRING, and/or I2D (see all 171)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=2 
    HIST1H4BP628053I2D: score=2 
    HIST1H4CP628053I2D: score=2 
    HIST1H4DP628053I2D: score=2 
    HIST1H4EP628053I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364rRNA processing IEA--

    HEATR1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HEATR1 (HEAT1)

    Search CenterWatch for drugs/clinical trials and news about HEATR1 / HEAT1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HEATR1 gene: 
    NM_018072.5  

    Unigene Cluster for HEATR1:

    HEAT repeat containing 1
    Hs.708114  [show with all ESTs]
    Unigene Representative Sequence: NM_018072
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000366582(uc009xgh.2 uc001hyd.2) ENST00000366581 ENST00000490339
    ENST00000483073 ENST00000366579(uc001hye.2)
    miRNA
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    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate HEATR1 (see all 25):
    hsa-miR-3910 hsa-miR-548j hsa-miR-4254 hsa-miR-548i hsa-miR-649 hsa-miR-124 hsa-miR-506 hsa-miR-548d-5p
    SwitchGear 3'UTR luciferase reporter plasmidHEATR1 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene RNAi products in human, mouse, rat for HEATR1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HEATR1
    Clone
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    GenScript: all cDNA clones in your preferred vector: HEATR1 (NM_018072)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HEATR1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HEATR1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HEATR1

    Additional mRNA sequence: 

    AK001221.1 AK095692.1 AK098212.1 AK125663.1 AK304129.1 AK316413.1 BC011983.1 BC035302.1 
    BC062442.1 BC065205.1 BC130000.1 BC150614.1 

    18 DOTS entries:

    DT.92447363  DT.100880001  DT.100843015  DT.100652904  DT.121380778  DT.40312083  DT.100676619  DT.100879997 
    DT.99998664  DT.121380791  DT.121380825  DT.121380870  DT.121380879  DT.40128822  DT.92447375  DT.95347185 
    DT.95371294  DT.449762 

    24/240 AceView cDNA sequences (see all 240):

    AA909823 CK825220 AA479792 AA836949 AI417974 AI114709 BE220019 CA413253 
    AL702001 BF476642 BM797705 AL599555 BM792741 BM789333 AK001221 AV651843 
    BP872835 AI886585 BG231504 AW613828 AI079533 AA827672 AA149823 AA436617 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for HEATR1 (see all 11)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18a · 18b ^ 19a · 19b ^ 20a ·
    SP1:                                                                                                                                                            
    SP2:                          -                                               -                                                                                 
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 20b ^ 21a · 21b ^ 22a · 22b · 22c ^ 23a · 23b · 23c ^ 24a · 24b ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38 ^ 39a ·
    SP1:                                -     -     -     -                                                                                                         
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                -                                                                                                                           
    SP5:                                -                                                                                                                           

    ExUns: 39b ^ 40 ^ 41a · 41b ^ 42 ^ 43 ^ 44 ^ 45
    SP1:                    -                           
    SP2:                                                
    SP3:                                                
    SP4:                                                
    SP5:                                                


    ECgene alternative splicing isoforms for HEATR1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HEATR1 expression in normal human tissues (normalized intensities)      HEATR1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTACTTTTGG
    HEATR1 Expression
    About this image


    HEATR1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Umbilical Cord (Extraembryonic Tissues)
             huvec   
     
     Endothelium (Extraembryonic Tissues)
             huvec   
     
     Testis (Reproductive System)

    See HEATR1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HEATR1

    SOURCE GeneReport for Unigene cluster: Hs.708114
        SABiosciences Custom PCR Arrays for HEATR1
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HEATR1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HEATR1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for HEATR1 gene from 9/23 species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Heatr11 , 5 HEAT repeat containing 11, 5 83.17(n)1
    83.85(a)1
      13 (4.56 cM)5
    2179951  NM_144835.41  NP_659084.31 
     123953985 
    chicken
    (Gallus gallus)
    Aves HEATR11 HEAT repeat containing 1 69.2(n)
    65.89(a)
      425734  XM_422958.3  XP_422958.3 
    lizard
    (Anolis carolinensis)
    Reptilia HEATR16
    HEAT repeat containing 1
    52(a)
    1 ↔ 1
    1(218926082-218963453)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.35162 Xenopus laevis transcribed sequence with moderate similarity more 72.77(n)    BX850230.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi69e122 wufi69e12 72.37(n)   334446  BC055128.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(2)k090221 lethal (2) k09022 43.39(n)
    31.32(a)
      33960  NM_135235.2  NP_609079.2 
    worm
    (Caenorhabditis elegans)
    Secernentea toe-11 Protein TOE-1 40.55(n)
    25.02(a)
      173779  NM_062381.3  NP_494782.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes UTP10(YJL109C)4
    UTP101
    Nucleolar protein, component of the small subunit (SSU) more4
    Utp10p1
    42.79(n)1
    28.06(a)1
      10(217309-212000)4
    8533351, 4  NP_012426.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G065301 U3 small nucleolar RNA-associated protein 10 and NUC211 more 41.38(n)
    26.67(a)
      819831  NM_001202900.1  NP_001189829.1 


    ENSEMBL Gene Tree for HEATR1 (if available)
    TreeFam Gene Tree for HEATR1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1645 SNPs in HEATR1 are shown (see all 1645)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1152370981,2
    C,F--236716833(+) TAGGCT/CATGCA 1 -- int12Minor allele frequency- C:0.03NA EA 240
    rs2022009351,2
    --236716887(+) TTAGGC/TGAGGA 2 S syn10--------
    rs66647301,2,4
    C,F,H--236716888(+) TAGGCG/AAGGAG 2 /S /L mis1 ese311Minor allele frequency- A:0.04NS EA NA WA EU 6461
    rs2008541691,2
    C--236716900(+) CTCTCA/GTCTTT 2 T M mis10--------
    rs1491452081,2
    C,F--236716934(+) TTTCCA/GAAGAG 2 R W mis12Minor allele frequency- G:0.00NA EU 5873
    rs1875080751,2
    C--236716947(+) TCATCC/TGCCAT 2 A syn10--------
    rs22756851,2
    C,F,A,H--236716959(+) GCCACT/CGAAAA 2 /S syn127Minor allele frequency- C:0.44EA MN NS NA CSA WA EU 9973
    rs1413391611,2
    F--236716974(+) GCGATG/ACATGG 2 /C syn11Minor allele frequency- A:0.00NA 4550
    rs1390220591,2
    F--236716985(+) TATCAG/CGTGCT 2 /L /V mis11Minor allele frequency- C:0.00NA 4550
    rs2003550031,2
    --236717013(+) AATTTC/TTCTTC 2 E syn10--------

    HapMap Linkage Disequilibrium report for HEATR1 (236712305 - 236767841 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for HEATR1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2725451CNV Deletion23290073
    esv2002103CNV Deletion18987734
    dgv552n71CNV Loss21882294
    esv995705CNV Gain20482838
    dgv60n27CNV Gain19166990
    nsv516855CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    HEATR1 for disorders           About MalaCards

    HEATR1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): HEATR1
    Human Genome Epidemiology (HuGE) Navigator: HEATR1 (1 document)

    Export disorders for HEATR1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HEATR1 gene, integrated from 9 sources (see all 43):
    (articles sorted by number of sources associating them with HEATR1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells. (PubMed id 17699751)1, 3 Prieto J.L. and McStay B. (2007)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
    5. VCP phosphorylation-dependent interaction partners pre vent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (2013)
    6. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    7. The functional interactome landscape of the human hist one deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (2013)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. Proteomic analysis of a4b1 integrin adhesion complexes reveals a-subunit-dependent protein recruitment. (PubMed id 22623428)1 Byron A....Humphries M.J. (2012)
    10. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55127 HGNC: 25517 AceView: FLJ10359 Ensembl:ENSG00000119285 euGenes: HUgn55127
    ECgene: HEATR1 Kegg: 55127 H-InvDB: HEATR1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HEATR1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HEATR1 gene:
    Search GeneIP for patents involving HEATR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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