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HDX Gene

protein-coding   GIFtS: 47
GCID: GC0XM083572

Highly Divergent Homeobox

(Previous name: chromosome X open reading frame 43)
(Previous symbol: CXorf43)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Highly Divergent Homeobox1 2
CXorf431 2 3
Chromosome X Open Reading Frame 431
D030011N01Rik2

External Ids:    HGNC: 264111   Entrez Gene: 1393242   Ensembl: ENSG000001652597   UniProtKB: Q7Z3533   

Export aliases for HDX gene to outside databases

Previous GC identifers: GC0XM083459 GC0XM077147


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for HDX Gene:
HDX (highly divergent homeobox) is a protein-coding gene. Diseases associated with HDX include panhypopituitarism x-linked, and panhypopituitarism. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_011651.18  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HDX gene promoter:
         Pbx1a   AML1a   Egr-1   Pax-2   RelA   CUTL1   NF-kappaB   MEF-2A   aMEF-2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHDX promoter sequence
   Search Chromatin IP Primers for HDX

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HDX


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq21.1   Ensembl cytogenetic band:  Xq21.1   HGNC cytogenetic band: Xq21.1

HDX Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HDX gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM083572:  view genomic region     (about GC identifiers)

Start:
83,572,882 bp from pter      End:
83,757,487 bp from pter
Size:
184,606 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HDX_HUMAN, Q7Z353 (See protein sequence)
Recommended Name: Highly divergent homeobox  
Size: 690 amino acids; 77206 Da
Sequence caution: Sequence=CAI42095.1; Type=Erroneous gene model prediction;
1 PDB 3D structure from and Proteopedia for HDX:
2DA4 (3D)    
Secondary accessions: A8K1Y5 B7ZL18 Q5JZB4 Q96NK7
Alternative splicing: 2 isoforms:  Q7Z353-1   Q7Z353-2   

Explore the universe of human proteins at neXtProt for HDX: NX_Q7Z353

Explore proteomics data for HDX at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HDX Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001170949.1  NP_001170950.1  NP_653258.2  

    ENSEMBL proteins: 
     ENSP00000297977   ENSP00000423670   ENSP00000362272   ENSP00000387790  

    HDX Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for HDX
    OriGene Custom MassSpec
    OriGene Custom Protein Services for HDX
    GenScript Custom Purified and Recombinant Proteins Services for HDX
    Novus Biologicals HDX Protein
    Novus Biologicals HDX Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HDX

    HDX Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for HDX
    Novus Biologicals HDX Antibodies
    Abcam antibodies for HDX
    Cloud-Clone Corp. Antibodies for HDX
    Search ThermoFisher Antibodies for HDX
    LSBio Antibodies in human, mouse, rat for HDX

    HDX Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for HDX
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for HDX
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for HDX
    Cloud-Clone Corp. CLIAs for HDX


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    POU: Homeoboxes / POU class

    2 InterPro protein domains:
     IPR001356 Homeobox_dom
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q7Z353

    ProtoNet protein and cluster: Q7Z353

    UniProtKB/Swiss-Prot: HDX_HUMAN, Q7Z353
    Similarity: Contains 2 homeobox DNA-binding domains


    HDX for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0043565sequence-specific DNA binding IEA--
         
    HDX for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for HDX:
     Decreased POU5F1-GFP protein e 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Hdx):
     normal 

    HDX for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HDX
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HDX

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HDX
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HDX

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat HDX using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HDX (see all 59):
    hsa-miR-323-3p hsa-let-7d hsa-miR-513a-5p hsa-miR-134 hsa-miR-139-5p hsa-miR-632 hsa-miR-346 hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidHDX 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for HDX
    Predesigned siRNA for gene silencing in human, mouse, rat HDX

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for HDX

    Clone
    Products:
         
    OriGene clones in human, mouse for HDX (see all 14)
    OriGene ORF clones in mouse, rat for HDX
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): HDX (NM_144657)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HDX
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HDX

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for HDX
    Browse ESI BIO Cell Lines and PureStem Progenitors for HDX 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HDX


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HDX_HUMAN, Q7Z353: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    HDX for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HDX
    Interactions:

        Search GeneGlobe Interaction Network for HDX

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for HDX (Q7Z3533 ENSP000002979774) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    POLR1EQ9GZS13, ENSP000003670294I2D: score=1 STRING: ENSP00000367029
    SUFUQ9UMX13, ENSP000003589184I2D: score=1 STRING: ENSP00000358918
    ZBTB16Q055163, ENSP000003381574I2D: score=1 STRING: ENSP00000338157
    YWHAEP622583I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-templated ----

    HDX for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HDX



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HDX gene (3 alternative transcripts): 
    NM_001177478.1  NM_001177479.1  NM_144657.4  

    Unigene Cluster for HDX:

    Highly divergent homeobox
    Hs.559546  [show with all ESTs]
    Unigene Representative Sequence: NM_001177479
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297977(uc011mqv.2 uc004eel.2 uc004eek.2) ENST00000506585
    ENST00000373177 ENST00000472135 ENST00000449553
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HDX using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HDX (see all 59):
    hsa-miR-323-3p hsa-let-7d hsa-miR-513a-5p hsa-miR-134 hsa-miR-139-5p hsa-miR-632 hsa-miR-346 hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidHDX 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for HDX
    Predesigned siRNA for gene silencing in human, mouse, rat HDX
    Clone
    Products:
         
    OriGene clones in human, mouse for HDX (see all 14)
    OriGene ORF clones in mouse, rat for HDX
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): HDX (NM_144657)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HDX
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HDX
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for HDX
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HDX
      QuantiTect SYBR Green Assays in human, mouse, rat HDX
      QuantiFast Probe-based Assays in human, mouse, rat HDX

    Additional mRNA sequence: 

    AK055240.1 AK290050.1 BC101720.1 BC101722.1 BC143522.1 BX538112.1 BX649166.1 

    6 DOTS entries:

    DT.40299958  DT.121312066  DT.101963862  DT.40282730  DT.121312067  DT.40127193 

    23 AceView cDNA sequences:

    CB160004 BX538112 CN482942 NM_144657 AL707138 AK055240 BX649166 BX102212 
    BU686266 CA844238 BG460132 AI263178 CA866462 BI497112 AI564135 AA927183 
    BE157560 BX489268 W25547 AA625538 AA969889 W19337 BE157489 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for HDX (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
    SP1:                    -     -           -                             -                                             
    SP2:                    -     -     -                                   -                                             
    SP3:                    -     -                                                                                       
    SP4:                                                                                                                  
    SP5:                    -     -     -     -                                                                           


    ECgene alternative splicing isoforms for HDX

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HDX expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCTTCACCA
    HDX Expression
    About this image

    HDX Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HDX Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.559546
        Custom PCR Arrays for HDX
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for HDX
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HDX
    QuantiTect SYBR Green Assays in human, mouse, rat HDX
    QuantiFast Probe-based Assays in human, mouse, rat HDX
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HDX

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HDX gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hdx1 , 5 highly divergent homeobox1, 5 90.97(n)1
    90.87(a)1
      X (48.29 cM)5
    2455961  NM_001080549.21  NP_001074018.11 
     1115699315 
    chicken
    (Gallus gallus)
    Aves HDX1 highly divergent homeobox 79.7(n)
    77.03(a)
      422272  NM_001031120.3  NP_001026291.1 
    lizard
    (Anolis carolinensis)
    Reptilia HDX6
    highly divergent homeobox
    69(a)
    1 ↔ 1
    GL343202.1(710727-743670)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia hdx1 highly divergent homeobox 64.7(n)
    58.2(a)
      100144657  XM_004916891.1  XP_004916948.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7979481 highly divergent homeobox 52.48(n)
    45.67(a)
      797948  NM_001202494.1  NP_001189423.1 


    ENSEMBL Gene Tree for HDX (if available)
    TreeFam Gene Tree for HDX (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HDX (see all 2947)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1916991391,2
    --83546961(+) AAACAA/GAAAAA 3 -- ds50010--------
    rs1380908191,2
    C--83547229(+) GAACCA/GTATTT 3 -- ds50010--------
    rs1839601651,2
    --83547346(+) TTATTA/GCCTCT 3 -- ut310--------
    rs735051771,2
    C,F--83547528(+) AGTATG/ATATTT 3 -- ut311Minor allele frequency- A:0.50WA 2
    rs1932641741,2
    --83547531(+) ATATAC/TTTTAA 3 -- ut310--------
    rs1853788571,2
    --83547542(+) TGAAAC/TAATTT 3 -- ut310--------
    rs1903272181,2
    --83547676(+) ATTATA/TGCATT 3 -- ut310--------
    rs1814297061,2
    --83547788(+) TGGTAC/TTGATA 3 -- ut310--------
    rs1842894551,2
    --83547937(+) AATGTC/TTTTTA 3 -- ut310--------
    rs1886627031,2
    --83548157(+) AATGGC/TTTCTT 3 -- ut310--------

    HapMap Linkage Disequilibrium report for HDX (83572882 - 83757487 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for HDX:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2740264CNV Deletion23290073
    nsv519860CNV Gain19592680

    Human Gene Mutation Database (HGMD): HDX
    Locus Specific Mutation Databases (LSDB): HDX

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HDX
    DNA2.0 Custom Variant and Variant Library Synthesis for HDX

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for HDX:    
    About MalaCards
    panhypopituitarism x-linked    panhypopituitarism


    HDX for disorders           About GeneDecksing

    Genetic Association Database (GAD): HDX

    Export disorders for HDX gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HDX gene integrated from 10 sources:
    (articles sorted by number of sources associating them with HDX)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. 14-3-3 epsilon dynamically interacts with key components of mitogen-activated protein kinase signal module for selective modulation of the TNF-alpha-induced time course-dependent NF-kappaB activity. (PubMed id 20462248)1 Zuo S....Chen X. (J. Proteome Res. 2010)
    3. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (Cell 2010)
    4. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PubMed id 17903294)4 Yang Q....O'Donnell C.J. (BMC Med. Genet. 2007)
    5. Genome-wide association of sleep and circadian phenotypes. (PubMed id 17903308)4 Gottlieb D.J....Wilk J.B. (BMC Med. Genet. 2007)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (Nature 2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 139324 HGNC: 26411 AceView: CXorf43 Ensembl:ENSG00000165259 euGenes: HUgn139324
    ECgene: HDX H-InvDB: HDX

    (According to HUGE)
    About This Section

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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HDX Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HDX gene:
    Search GeneIP for patents involving HDX

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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