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HDGFRP3 Gene

protein-coding   GIFtS: 45
GCID: GC15M083784

Hepatoma-Derived Growth Factor, Related Protein 3


  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Hepatoma-Derived Growth Factor 22 3
HDGF-22 3
HDGF22 3
HRP-32 3
Hepatoma-Derived Growth Factor, Related Protein 32
Hepatoma-Derived Growth Factor-Related Protein 32

External Ids:    Entrez Gene: 508102   Ensembl: ENSG000001665037   UniProtKB: Q9Y3E13   

Export aliases for HDGFRP3 gene to outside databases

Previous GC identifers: GC15M079733 GC15M076838 GC15M081385 GC15M081526 GC15M081597 GC15M083806 GC15M060070


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for HDGFRP3 Gene:
HDGFRP3 is a protein-coding gene. Diseases associated with HDGFRP3 include congenital diaphragmatic hernia, and cryptorchidism. GO annotations related to this gene include growth factor activity. An important paralog of this gene is HDGF.

UniProtKB/Swiss-Prot: HDGR3_HUMAN, Q9Y3E1
Function: Enhances DNA synthesis and may play a role in cell proliferation

Gene Wiki entry for HDGFRP3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000015.10  NT_010194.18  NC_018926.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HDGFRP3 gene promoter:
         STAT5B   RFX1   POU3F1   STAT6   RelA   NF-kappaB   NF-kappaB1   Pax-4a   E47   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHDGFRP3 promoter sequence
   Search Chromatin IP Primers for HDGFRP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HDGFRP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q25.2   Ensembl cytogenetic band:  15q25.2   

HDGFRP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HDGFRP3 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M083784:  view genomic region     (about GC identifiers)

Start:
83,784,320 bp from pter      End:
83,876,770 bp from pter
Size:
92,451 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: HDGR3_HUMAN, Q9Y3E1 (See protein sequence)
Recommended Name: Hepatoma-derived growth factor-related protein 3  
Size: 203 amino acids; 22620 Da

Explore the universe of human proteins at neXtProt for HDGFRP3: NX_Q9Y3E1

Explore proteomics data for HDGFRP3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys66
  • Modification sites at PhosphoSitePlus

  • See HDGFRP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057157.1  
    ENSEMBL proteins: 
     ENSP00000455388   ENSP00000299633   ENSP00000455425   ENSP00000457346   ENSP00000456699  

    HDGFRP3 Human Recombinant Protein Products:

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    LSBio Antibodies in human, mouse, rat for HDGFRP3

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR000313 PWWP_dom

    Graphical View of Domain Structure for InterPro Entry Q9Y3E1

    ProtoNet protein and cluster: Q9Y3E1

    1 Blocks protein domain: IPB000313 PWWP domain

    UniProtKB/Swiss-Prot: HDGR3_HUMAN, Q9Y3E1
    Similarity: Belongs to the HDGF family
    Similarity: Contains 1 PWWP domain


    HDGFRP3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HDGR3_HUMAN, Q9Y3E1
    Function: Enhances DNA synthesis and may play a role in cell proliferation

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008083growth factor activity IEA--
         
    HDGFRP3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HDGFRP3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HDGFRP3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HDGFRP3

    miRNA
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    Block miRNA regulation of human, mouse, rat HDGFRP3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HDGFRP3 (see all 19):
    hsa-miR-3607-3p hsa-miR-875-5p hsa-miR-578 hsa-miR-144 hsa-miR-550b hsa-miR-548x hsa-miR-891b hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidHDGFRP3 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for HDGFRP3
    Predesigned siRNA for gene silencing in human, mouse, rat HDGFRP3

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: HDGFRP3 (NM_016073)
    Sino Biological Human cDNA Clone for HDGFRP3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HDGFRP3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HDGFRP3

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HDGFRP3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HDGR3_HUMAN, Q9Y3E1: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IEA--

    HDGFRP3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HDGFRP3
    Interactions:

        Search GeneGlobe Interaction Network for HDGFRP3

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for HDGFRP3 (Q9Y3E13 ENSP000002996334) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMURF1Q9HCE73, ENSP000003546214I2D: score=2 STRING: ENSP00000354621
    SMURF2Q9HAU43, ENSP000002624354I2D: score=2 STRING: ENSP00000262435
    SHC1P293533I2D: score=2 
    GRB2ENSP000003390074STRING: ENSP00000339007
    TERF2IPENSP000003000864STRING: ENSP00000300086
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008283cell proliferation NAS10581169

    HDGFRP3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HDGFRP3 (HDGR3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HDGFRP3 gene: 
    NM_016073.3  

    Unigene Cluster for HDGFRP3:

    Hepatoma-derived growth factor, related protein 3
    Hs.513954  [show with all ESTs]
    Unigene Representative Sequence: AL133102
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000568294 ENST00000299633(uc002bjs.1) ENST00000563790 ENST00000562702
    ENST00000568129 ENST00000563404
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HDGFRP3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HDGFRP3 (see all 19):
    hsa-miR-3607-3p hsa-miR-875-5p hsa-miR-578 hsa-miR-144 hsa-miR-550b hsa-miR-548x hsa-miR-891b hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidHDGFRP3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for HDGFRP3
    Predesigned siRNA for gene silencing in human, mouse, rat HDGFRP3
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    GenScript: all cDNA clones in your preferred vector: HDGFRP3 (NM_016073)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HDGFRP3
    Primer
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    OriGene qPCR primer pairs and template standards for HDGFRP3
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HDGFRP3
      QuantiTect SYBR Green Assays in human, mouse, rat HDGFRP3
      QuantiFast Probe-based Assays in human, mouse, rat HDGFRP3

    Additional mRNA sequence: 

    AB029156.1 AF110642.1 AF151900.1 AK001280.1 AL109689.1 AL109779.1 AL133102.1 BC015483.1 
    BC040554.1 HQ234314.1 

    13 DOTS entries:

    DT.99972920  DT.312973  DT.100886600  DT.92442881  DT.121066699  DT.92442891  DT.100886581  DT.100886586 
    DT.100886588  DT.97783410  DT.92012097  DT.92442883  DT.95278051 

    Selected AceView cDNA sequences (see all 185):

    BE886684 CK299643 AI027718 AW872906 BM979057 AI654815 BG201738 CR611705 
    CA395457 AL109779 AI784055 BQ723640 AW664393 H97413 AA742695 AL533005 
    CR604509 BX283676 BU179069 CA312509 CR596986 AI478857 BX394454 BE042914 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for HDGFRP3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7
    SP1:              -                                             
    SP2:                                                            
    SP3:                                                            



    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HDGFRP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    HDGFRP3 Expression
    About this image


    HDGFRP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Testis (Reproductive System)
    HDGFRP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HDGFRP3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.513954

    UniProtKB/Swiss-Prot: HDGR3_HUMAN, Q9Y3E1
    Tissue specificity: Detected in testis, heart, spinal cord and brain

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HDGFRP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for HDGFRP3 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hdgfrp31 , 5 hepatoma-derived growth factor, related protein 31, 5 94.39(n)1
    97.52(a)1
      7 (45.71 cM)5
    298771  NM_013886.41  NP_038914.21 
     818812515 
    chicken
    (Gallus gallus)
    Aves HDGFRP31 hepatoma-derived growth factor, related protein 3 87.5(n)
    97.16(a)
      415463  XM_413841.3  XP_413841.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    97(a)
    1 ↔ 1
    GL343836.1(93335-122248)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia hdgfrp31 hepatoma-derived growth factor, related protein 3 81.02(n)
    87.62(a)
      100125195  NM_001103080.1  NP_001096550.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CF549712.12   -- 74.79(n)    CF549712.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG79466
    --
    11(a)
    1 → many
    3R(25878236-25880419)
    worm
    (Caenorhabditis elegans)
    Secernentea C06A5.36
    Protein C06A5.3, isoform b (C06A5.3) mRNA, complet...
    6(a)
    1 → many
    I(5986492-5990581) WBGene00015501


    ENSEMBL Gene Tree for HDGFRP3 (if available)
    TreeFam Gene Tree for HDGFRP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HDGFRP3 gene
    HDGF2  PSIP12  HDGFL12  HDGFRP22  
    4 SIMAP similar genes for HDGFRP3 using alignment to 4 protein entries:     HDGR3_HUMAN (see all proteins):
    PSIP1    HDGFRP2    HDGF    HDGFL1

    HDGFRP3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for HDGFRP3
    PGOHUM00000262826


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HDGFRP3 (see all 1169)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1437082561,2
    --83806634(+) TAATAC/TCAAAT 1 -- int10--------
    rs1866201111,2
    --83806670(+) GGTAAA/GTATGT 1 -- int10--------
    rs19031,2
    C--83806973(+) TTTNTG/TTTTTT 1 -- ut311Minor allele frequency- T:0.00NA 2
    rs1918257411,2
    --83807020(+) GAATAC/TGCGAA 1 -- ut310--------
    rs740282411,2
    C,F--83807295(+) AATGTT/AAAGTA 1 -- ut311Minor allele frequency- A:0.50WA 2
    rs754692421,2
    C,F--83807619(+) TTCTTA/CAGCAT 1 -- ut311Minor allele frequency- C:0.11EA 120
    rs1480945571,2
    C--83807643(+) CATCTA/GAAAAA 1 -- ut310--------
    rs1887236861,2
    --83807713(+) ATCATA/TACTGC 1 -- ut310--------
    rs1928241361,2
    --83807763(+) AAATCC/TTGATA 1 -- ut310--------
    rs2014867111,2
    F--83808046(+) AAAAAG/AAAAGA 1 -- int11Minor allele frequency- A:0.01EU 887

    HapMap Linkage Disequilibrium report for HDGFRP3 (83784320 - 83876770 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for HDGFRP3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2478815CNV Deletion19546169
    nsv94888CNV Insertion16902084

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HDGFRP3
    DNA2.0 Custom Variant and Variant Library Synthesis for HDGFRP3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    5 diseases for HDGFRP3:    
    About MalaCards
    congenital diaphragmatic hernia    cryptorchidism    mantle cell lymphoma    hiv-1
    neuronitis

    1 disease from the University of Copenhagen DISEASES database for HDGFRP3:
    Congenital diaphragmatic hernia

    HDGFRP3 for disorders           About GeneDecksing


    Export disorders for HDGFRP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HDGFRP3 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with HDGFRP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    4. A new member of a hepatoma-derived growth factor gene family can translocate to the nucleus. (PubMed id 10581169)1, 2 Ikegame K.... Nakamura H. (Biochem. Biophys. Res. Commun. 1999)
    5. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). (PubMed id 23503679)1 Zhu J....Elledge S.J. (Nat. Biotechnol. 2013)
    6. Depletion of hepatoma-derived growth factor-related protein-3 induces apoptotic sensitization of radioresistant A549 cells via reactive oxygen species-dependent p53 activation. (PubMed id 24012673)1 Yun H.S....Hwang S.G. (Biochem. Biophys. Res. Commun. 2013)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor. (PubMed id 21706016)1 Bisson N....Pawson T. (Nat. Biotechnol. 2011)
    10. Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 50810 AceView: HDGFRP3 Ensembl:ENSG00000166503 euGenes: HUgn50810

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    (Patent information from GeneIP,
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    Patent Information for HDGFRP3 gene:
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