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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HDDC2 Gene

protein-coding   GIFtS: 50
GCID: GC06M125596

HD Domain Containing 2

(Previous name: chromosome 6 open reading frame 74)
(Previous symbol: C6orf74)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
HD Domain Containing 21 2     HCV NS5A-Transactivated Protein 22 3
C6orf741 2 3     Chromosome 6 Open Reading Frame 741
Hepatitis C Virus NS5A-Transactivated Protein 22 3     dJ167O5.22
NS5ATP22 3     HD Domain-Containing Protein 22

External Ids:    HGNC: 210781   Entrez Gene: 510202   Ensembl: ENSG000001119067   UniProtKB: Q7Z4H33   

Export aliases for HDDC2 gene to outside databases

Previous GC identifers: GC06M125639 GC06M123173


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for HDDC2 Gene: 
HDDC2 (HD domain containing 2) is a protein-coding gene. Diseases associated with HDDC2 include hepatitis c, and hepatitis. GO annotations related to this gene include phosphoric diester hydrolase activity and metal ion binding.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_025741.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HDDC2 gene promoter:
         SRF   SRF (504 AA)   FOXD1   Cdc5   Meis-1b   RORalpha2   Meis-1a   LyF-1   Meis-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for HDDC2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HDDC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q13-q24.3   Ensembl cytogenetic band:  6q22.31   HGNC cytogenetic band: 6q13-q24.3

HDDC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HDDC2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M125596:  view genomic region     (about GC identifiers)

Start:
125,596,496 bp from pter      End:
125,623,282 bp from pter
Size:
26,787 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HDDC2_HUMAN, Q7Z4H3 (See protein sequence)
Recommended Name: HD domain-containing protein 2  
Size: 204 amino acids; 23390 Da
Sequence caution: Sequence=AAH03357.2; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for HDDC2:
4DMB (3D)    
Secondary accessions: Q5TDQ4 Q6NZ49 Q9BTT2 Q9BV31 Q9Y3D1
Alternative splicing: 3 isoforms:  Q7Z4H3-1   Q7Z4H3-2   Q7Z4H3-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for HDDC2: NX_Q7Z4H3

Explore proteomics data for HDDC2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7Z4H3

  • HDDC2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HDDC2 Protein Expression
    REFSEQ proteins: NP_057147.2  
    ENSEMBL proteins: 
     ENSP00000316242   ENSP00000381220   ENSP00000357361  

    Human Recombinant Protein Products for HDDC2: 
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    Novus Biologicals HDDC2 Protein
    Novus Biologicals HDDC2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HDDC2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--

    HDDC2 for ontologies           About GeneDecksing



    HDDC2 Antibody Products: 
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    Cloud-Clone Corp. ELISAs for HDDC2 
    Cloud-Clone Corp. CLIAs for HDDC2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR006674 HD_domain
     IPR003607 HD/PDEase_dom

    Graphical View of Domain Structure for InterPro Entry Q7Z4H3

    ProtoNet protein and cluster: Q7Z4H3

    1 Blocks protein domain: IPB006674 Metal-dependent phosphohydrolase

    UniProtKB/Swiss-Prot: HDDC2_HUMAN, Q7Z4H3
    Similarity: Belongs to the HDDC2 family
    Similarity: Contains 1 HD domain


    HDDC2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0005515protein binding IPI--
    GO:0008081phosphoric diester hydrolase activity IEA--
    GO:0046872metal ion binding IEA--
         
    HDDC2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for HDDC2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HDDC2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HDDC2 
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    miRNA
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate HDDC2:
    hsa-miR-149 hsa-miR-185 hsa-miR-1324 hsa-miR-4306 hsa-miR-551b* hsa-miR-103a-2* hsa-miR-421
    SwitchGear 3'UTR luciferase reporter plasmidHDDC2 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HDDC2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HDDC2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5/14 Interacting proteins for HDDC2 (Q7Z4H31, 3 ENSP000003812204) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    WDR12Q9GZL73, ENSP000002610154I2D: score=3 STRING: ENSP00000261015
    CHMP2AO436333I2D: score=5 
    BOP1Q141373I2D: score=1 
    C12orf44Q9BSB43I2D: score=1 
    DDA1Q9BW613I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HDDC2

    Search CenterWatch for drugs/clinical trials and news about HDDC2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HDDC2 gene: 
    NM_016063.2  

    Unigene Cluster for HDDC2:

    HD domain containing 2
    Hs.32826  [show with all ESTs]
    Unigene Representative Sequence: AK128067
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000318787 ENST00000398153(uc003qaa.1) ENST00000368377(uc003qab.1)

    miRNA
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate HDDC2:
    hsa-miR-149 hsa-miR-185 hsa-miR-1324 hsa-miR-4306 hsa-miR-551b* hsa-miR-103a-2* hsa-miR-421
    SwitchGear 3'UTR luciferase reporter plasmidHDDC2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for HDDC2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HDDC2
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HDDC2
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HDDC2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HDDC2

    Additional mRNA sequence: 

    AF151888.1 AF529363.1 AK128067.1 BC001671.2 BC003357.1 BC061520.1 BC066332.1 

    12 DOTS entries:

    DT.92439299  DT.101984240  DT.86853114  DT.100818402  DT.100818399  DT.92439291  DT.95183747  DT.421178 
    DT.121377160  DT.97820709  DT.92439290  DT.97859897 

    24/255 AceView cDNA sequences (see all 255):

    BQ433877 BU621319 BQ671076 AA887294 AI167748 BC001671 BU146438 BM981139 
    BM675013 BQ010186 BU681507 BG032061 BE908758 AA364113 BU188882 CD674664 
    BC003357 CB159149 BM713430 BM973220 W42520 BQ083114 W73305 BM679232 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for HDDC2 (see all 12)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b · 9c · 9d · 9e · 9f
    SP1:        -     -     -     -                 -           -     -           -     -           -     -                                       
    SP2:                          -                 -           -     -           -     -           -     -                                       
    SP3:                                            -           -     -           -     -           -     -                                       
    SP4:        -     -     -     -                 -     -     -     -           -     -           -     -                                       
    SP5:                          -                 -     -     -     -           -     -           -     -                                       


    ECgene alternative splicing isoforms for HDDC2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HDDC2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATGAACACT
    HDDC2 Expression
    About this image


    See HDDC2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HDDC2

    SOURCE GeneReport for Unigene cluster: Hs.32826
        SABiosciences Custom PCR Arrays for HDDC2
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for HDDC2 gene from 10/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hddc21 , 5 HD domain containing 21, 5 85.4(n)1
    89.69(a)1
      10 (17.34 cM)5
    696921  NM_027168.21  NP_081444.11 
     313133825 
    chicken
    (Gallus gallus)
    Aves HDDC21 HD domain containing 2 74.91(n)
    78.35(a)
      421719  XM_419755.3  XP_419755.1 
    lizard
    (Anolis carolinensis)
    Reptilia HDDC26
    Uncharacterized protein
    80(a)
    1 ↔ 1
    1(180738607-180752671)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.239212 Xenopus laevis transcribed sequence with weak similarity more 77.21(n)    CB198244.2 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb71h082 wufb71h08 73.72(n)   322725  CK355860.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG110501 CG11050 49.83(n)
    44.5(a)
      33924  NM_135208.5  NP_609052.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F45F2.96
    Protein F45F2.9, isoform b
    37(a)
    1 ↔ 1
    V(8512671-8513461)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes (YBR242W)4
    YBR242W1
    Putative protein of unknown function; green fluorescent more4
    hypothetical protein1
    51.02(n)1
    44.13(a)1
      2(704670-705386)4
    8525441, 4  NP_009801.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G238201 Metal-dependent phosphohydrolase 59.3(n)
    52.33(a)
      816914  NM_201793.3  NP_973522.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g01791001 hypothetical protein 56.98(n)
    55.23(a)
      4328498  NM_001052616.1  NP_001046081.1 


    ENSEMBL Gene Tree for HDDC2 (if available)
    TreeFam Gene Tree for HDDC2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/639 SNPs in HDDC2 are shown (see all 639)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1416896691,2
    --125596189(+) TAACCA/GTATAT 1 -- ds50010--------
    rs1863604411,2
    C--125596367(+) GCCTCA/GAAGGC 1 -- ds50010--------
    rs779564101,2
    C,F--125596478(+) TTCAAT/AGTAAA 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs1921048021,2
    --125596570(+) AATGAC/TCCCAG 1 -- ut310--------
    rs1834752961,2
    --125596609(+) ACATGC/TTTTTA 1 -- ut310--------
    rs94913521,2
    C,F,A,H--125596750(+) GTAGGT/ATTACA 1 -- ut3124Minor allele frequency- A:0.23NA NS EA WA CSA 2650
    rs10408031,2
    C,F,A,H--125596957(+) ATGAAT/CCTAGC 1 -- ut31 ese326Minor allele frequency- C:0.27MN NA NS EA WA CSA 2664
    rs94913531,2
    C,A,H--125597023(+) TATTCT/CAATAT 1 -- ut316Minor allele frequency- C:0.27WA CSA NA EA 363
    rs737724171,2
    C,F--125597103(+) ACTTTC/TATGAC 1 -- ut313Minor allele frequency- T:0.13WA CSA 122
    rs1175226581,2
    C,F--125597150(+) TGTATC/TACATT 1 -- ut311Minor allele frequency- T:0.04EA 120

    HapMap Linkage Disequilibrium report for HDDC2 (125596496 - 125623282 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for HDDC2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv886635CNV Loss21882294
    nsv820070CNV Gain19587683
    nsv886626CNV Gain21882294
    nsv886625CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing HDDC2
    DNA2.0 Custom Variant and Variant Library Synthesis for HDDC2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for HDDC2:    About MalaCards
    hepatitis c    hepatitis


    HDDC2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): HDDC2
    Human Genome Epidemiology (HuGE) Navigator: HDDC2 (1 document)

    Export disorders for HDDC2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HDDC2 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with HDDC2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    5. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    6. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
    7. Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study. (PubMed id 17903306)4 Newton-Cheh C....Larson M.G. (2007)
    8. Cloning and identification of NS5ATP2 gene and its spliced variant transactivated by hepatitis C virus non-structural protein 5A. (PubMed id 15188496)2 Yang Q.... Zhang S.-L. (2004)
    9. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51020 HGNC: 21078 AceView: C6orf74 Ensembl:ENSG00000111906 euGenes: HUgn51020
    ECgene: HDDC2 H-InvDB: HDDC2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HDDC2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HDDC2 gene:
    Search GeneIP for patents involving HDDC2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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