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Aliases for HDAC3 Gene

Aliases for HDAC3 Gene

  • Histone Deacetylase 3 2 3
  • EC 3.5.1.98 4 63
  • RPD3-2 3 4
  • SMAP45 3 4
  • HD3 3 4
  • RPD3 3

External Ids for HDAC3 Gene

Previous GeneCards Identifiers for HDAC3 Gene

  • GC05U990082
  • GC05M140983
  • GC05M141028
  • GC05M140980
  • GC05M136145

Summaries for HDAC3 Gene

Entrez Gene Summary for HDAC3 Gene

  • Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for HDAC3 Gene

HDAC3 (Histone Deacetylase 3) is a Protein Coding gene. Among its related pathways are Signaling by FGFR and Signaling by GPCR. GO annotations related to this gene include transcription factor binding and transcription corepressor activity. An important paralog of this gene is HDAC8.

UniProtKB/Swiss-Prot for HDAC3 Gene

  • Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 Lys-27 (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation (PubMed:21444723, PubMed:23911289). Contributes, together with XBP1 isoform 1, to the activation of NFE2L2-mediated HMOX1 transcription factor gene expression in a PI(3)K/mTORC2/Akt-dependent signaling pathway leading to endothelial cell (EC) survival under disturbed flow/oxidative stress (PubMed:25190803).

Tocris Summary for HDAC3 Gene

  • Histone Deacetylases (HDACs) are a group of enzymes closely related to sirtuins. They catalyze the removal of acetyl groups from lysine residues in histones and non-histone proteins, resulting in transcriptional repression. In general, they do not act autonomously but as components of large multiprotein complexes, such as pRb-E2F and mSin3A, that mediate important transcription regulatory pathways. There are three classes of HDACs; classes 1, 2 and 4, which are closely related Zn2+-dependent enzymes. HDACs are ubiquitously expressed and they can exist in the nucleus or cytosol. Their subcellular localization is effected by protein-protein interactions (for example HDAC-14.3.3 complexes are retained in the cytosol) and by the class to which they belong (class 1 HDACs are predominantly nuclear whilst class 2 HDACs shuttle between the nucleus and cytosol). HDACs have a role in cell growth arrest, differentiation and death and this has led to substantial interest in HDAC inhibitors as possible antineoplastic agents.

Gene Wiki entry for HDAC3 Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HDAC3 Gene

Genomics for HDAC3 Gene

Regulatory Elements for HDAC3 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for HDAC3 Gene

Start:
141,620,876 bp from pter
End:
141,636,870 bp from pter
Size:
15,995 bases
Orientation:
Minus strand

Genomic View for HDAC3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HDAC3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HDAC3 Gene

Proteins for HDAC3 Gene

  • Protein details for HDAC3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O15379-HDAC3_HUMAN
    Recommended name:
    Histone deacetylase 3
    Protein Accession:
    O15379
    Secondary Accessions:
    • D3DQE1
    • O43268
    • Q9UEI5
    • Q9UEV0

    Protein attributes for HDAC3 Gene

    Size:
    428 amino acids
    Molecular mass:
    48848 Da
    Quaternary structure:
    • Interacts with HDAC7 and HDAC9. Forms a heterologous complex at least with YY1. Interacts with DAXX, HDAC10 and DACH1. Found in a complex with NCOR1 and NCOR2. Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2. Interacts with BCOR, MJD2A/JHDM3A, NRIP1, PRDM6 and SRY. Interacts with BTBD14B. Interacts with GLIS2. Interacts (via the DNA-binding domain) with NR2C1; the interaction recruits phosphorylated NR2C1 to PML bodies for sumoylation. Component of the Notch corepressor complex. Interacts with CBFA2T3 and NKAP. Interacts with APEX1; the interaction is not dependent on the acetylated status of APEX1. Interacts with and deacetylates MAPK14. Interacts with ZMYND15. Interact with SMRT/NCOR2 and BCL6 on DNA enhancer elements. Interacts with INSM1 (PubMed:10655483, PubMed:10669754, PubMed:10860984, PubMed:10898795, PubMed:11006275, PubMed:11466315, PubMed:11533236, PubMed:11861901, PubMed:14525983, PubMed:14633989, PubMed:15297880, PubMed:15927959, PubMed:16569215, PubMed:18417529, PubMed:19409814, PubMed:23911289). Interacts with XBP1 isoform 1; the interaction occurs in endothelial cell (EC) under disturbed flow (PubMed:25190803).

    Three dimensional structures from OCA and Proteopedia for HDAC3 Gene

    Alternative splice isoforms for HDAC3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for HDAC3 Gene

Proteomics data for HDAC3 Gene at MOPED

Post-translational modifications for HDAC3 Gene

Other Protein References for HDAC3 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for HDAC3 (HDAC3)

Assay Products

  • Enzo Life Sciences assays for HDAC3
  • antibodies-online kits for HDAC3

Domains for HDAC3 Gene

Suggested Antigen Peptide Sequences for HDAC3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O15379

UniProtKB/Swiss-Prot:

HDAC3_HUMAN :
  • O15379
Family:
  • Belongs to the histone deacetylase family. HD type 1 subfamily.
genes like me logo Genes that share domains with HDAC3: view

No data available for Gene Families for HDAC3 Gene

Function for HDAC3 Gene

Molecular function for HDAC3 Gene

GENATLAS Biochemistry: histone deacetyltransferase 3,49kDa,ubiquitously expressed,binding to YY1,involved in negative regulation of transcription,modulator of chromatine structure,putatively involved in the pathogenesis of myeloproliferative disorders (potential tumor suppressor)
UniProtKB/Swiss-Prot CatalyticActivity: Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone
UniProtKB/Swiss-Prot Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 Lys-27 (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation (PubMed:21444723, PubMed:23911289). Contributes, together with XBP1 isoform 1, to the activation of NFE2L2-mediated HMOX1 transcription factor gene expression in a PI(3)K/mTORC2/Akt-dependent signaling pathway leading to endothelial cell (EC) survival under disturbed flow/oxidative stress (PubMed:25190803).
UniProtKB/Swiss-Prot Induction: Up-regulated by disturbed flow in umbilical vein endothelial cells in vitro (PubMed:25190803)

Enzyme Numbers (IUBMB) for HDAC3 Gene

Gene Ontology (GO) - Molecular Function for HDAC3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding --
GO:0003682 chromatin binding IDA 16569215
GO:0003714 transcription corepressor activity IMP 12628926
GO:0004407 histone deacetylase activity TAS 12711221
GO:0005515 protein binding IPI 10898795
genes like me logo Genes that share ontologies with HDAC3: view
genes like me logo Genes that share phenotypes with HDAC3: view

Animal Models for HDAC3 Gene

MGI Knock Outs for HDAC3:

Animal Model Products

CRISPR Products

No data available for miRNA , Transcription Factor Targeting and HOMER Transcription for HDAC3 Gene

Localization for HDAC3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HDAC3 Gene

Nucleus. Cytoplasm. Note=Colocalizes with XBP1 and AKT1 in the cytoplasm (PubMed:25190803). {ECO:0000269 PubMed:25190803}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for HDAC3 Gene COMPARTMENTS Subcellular localization image for HDAC3 gene
Compartment Confidence
cytoskeleton 5
nucleus 5
cytosol 2
plasma membrane 2

Gene Ontology (GO) - Cellular Components for HDAC3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000118 histone deacetylase complex TAS 12711221
GO:0005634 nucleus TAS 12711221
GO:0005654 nucleoplasm TAS --
GO:0005737 cytoplasm TAS 12711221
GO:0005794 Golgi apparatus IDA --
genes like me logo Genes that share ontologies with HDAC3: view

Pathways for HDAC3 Gene

genes like me logo Genes that share pathways with HDAC3: view

PCR Array Products

Gene Ontology (GO) - Biological Process for HDAC3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP 12628926
GO:0001934 positive regulation of protein phosphorylation IDA 25190803
GO:0006325 chromatin organization TAS --
GO:0006351 transcription, DNA-templated IEA --
GO:0006476 protein deacetylation IDA 17172643
genes like me logo Genes that share ontologies with HDAC3: view

Compounds for HDAC3 Gene

Compound Products

(5) Tocris Compounds for HDAC3 Gene

Compound Action Cas Number
FK 228 Potent and selective class I histone deacetylase inhibitor; antitumor [128517-07-7]
LMK 235 Selective HDAC4/HDAC5 inhibitor [1418033-25-6]
PCI 34051 Potent and selective histone deacetylase 8 (HDAC8) inhibitor; induces apoptosis in T cell-derived cell lines [950762-95-5]
SAHA Class I and II HDAC inhibitor [149647-78-9]
Trichostatin A Potent histone deacetylase inhibitor [58880-19-6]

(29) ApexBio Compounds for HDAC3 Gene

Compound Action Cas Number
AR-42 (OSU-HDAC42) Pan-HDAC inhibitor [935881-37-1]
Belinostat (PXD101) Novel and potent hydroxamate-type HDAC inhibitor [414864-00-9]
CI994 (Tacedinaline) HDAC1 and 3 inhibitor [112522-64-2]
CUDC-101 Multitargeted HDAC inhibitor [1012054-59-9]
CUDC-907 dual PI3K and HDAC inhibitor [1339928-25-4]
Droxinostat Selective HDAC inhibitor [99873-43-5]
Entinostat (MS-275,SNDX-275) Entinostat inhibits HDAC1 and HDAC3 but not HDAC8 [209783-80-2]
ITF2357 (Givinostat) HDAC inhibitor, inhibits class I and class II HDACs [732302-99-7]
JNJ-26481585 Potent pan-HDAC inhibitor [875320-29-9]
LAQ824 (NVP-LAQ824,Dacinostat) Novel and potent HDAC inhibitor [404951-53-7]
M344 Cell-permeable HDAC inhibitor [251456-60-7]
MC1568 Selective class IIa HDAC inhibitor [852475-26-4]
Mocetinostat (MGCD0103, MG0103) Class I selective HDAC inhibitor [726169-73-9]
Panobinostat (LBH589) Broad spectrum HDAC inhibitor, inhibits HDAC1-11 [404950-80-7]
PCI-24781 (CRA-024781) Novel pan-HDAC inhibitor [783355-60-2]
PCI-34051 Potent, specific HDAC8 inhibitor [950762-95-5]
Pracinostat (SB939) Pan-HDAC inhibitor, inhibits all HDAC isozymes except HDAC6 and HDAC7 [929016-96-6]
Resminostat (RAS2410) Potent inhibitor of HDAC classes I and II [864814-88-0]
RG2833 Brain-penetrant HDAC inhibitor [1215493-56-3]
RGFP966 Specific HDAC3 inhibitor [1396841-57-8]
Rocilinostat (ACY-1215) Selective HDAC6 inhibitor [1316214-52-4]
Romidepsin (FK228, depsipeptide) Potent HDAC1 and HDAC2 inhibitor [128517-07-7]
Scriptaid Cell-permeable HDAC inhibitor [287383-59-9]
Trichostatin A (TSA) Cell-permeable, non-competitive, and reversible HDAC inhibitor [58880-19-6]
Tubacin Selective HDAC6 inhibitor [1350555-93-9]
Tubastatin A Potent and selective HDAC6 inhibitor [1252003-15-8]
Tubastatin A HCl Potent and selective HDAC6 inhibitor [1310693-92-5]
Valproic acid sodium salt HDAC inhibitor [1069-66-5]
Vorinostat (SAHA, MK0683) Class I and II HDAC inhibitor [149647-78-9]

(1) HMDB Compounds for HDAC3 Gene

Compound Synonyms Cas Number PubMed IDs
Butyric acid
  • 1-Butyrate
107-92-6

(1) Drugbank Compounds for HDAC3 Gene

Compound Synonyms Cas Number Type Actions PubMed IDs
Vorinostat
  • MK0683
149647-78-9 target inhibitor

(14) Novoseek inferred chemical compound relationships for HDAC3 Gene

Compound -log(P) Hits PubMed IDs
suberoylanilide hydroxamic acid 74.5 3
trapoxin 67.4 1
butyrate 43.9 4
lysine 35.8 2
retinoic acid 34.8 8
genes like me logo Genes that share compounds with HDAC3: view

Transcripts for HDAC3 Gene

Unigene Clusters for HDAC3 Gene

Histone deacetylase 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for HDAC3

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HDAC3 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c · 12d ^ 13a · 13b ^ 14 ^
SP1: - - - - -
SP2: - - - -
SP3: - - - - - - - -
SP4: - - - - - - - - -
SP5: - - -
SP6: - -
SP7: - - - - - -
SP8:
SP9: -
SP10:
SP11:
SP12:

ExUns: 15 ^ 16
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:

Relevant External Links for HDAC3 Gene

GeneLoc Exon Structure for
HDAC3
ECgene alternative splicing isoforms for
HDAC3

Expression for HDAC3 Gene

mRNA expression in normal human tissues for HDAC3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for HDAC3 Gene

SOURCE GeneReport for Unigene cluster for HDAC3 Gene Hs.519632

mRNA Expression by UniProt/SwissProt for HDAC3 Gene

O15379-HDAC3_HUMAN
Tissue specificity: Widely expressed
genes like me logo Genes that share expressions with HDAC3: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for HDAC3 Gene

Orthologs for HDAC3 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for HDAC3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia HDAC3 35
  • 99.77 (n)
  • 100 (a)
HDAC3 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia HDAC3 35
  • 94.47 (n)
  • 100 (a)
HDAC3 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia HDAC3 35
  • 94.31 (n)
  • 100 (a)
HDAC3 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Hdac3 35
  • 92.37 (n)
  • 99.77 (a)
Hdac3 16
Hdac3 36
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia HDAC3 36
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 49 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Hdac3 35
  • 92.76 (n)
  • 99.77 (a)
chicken
(Gallus gallus)
Aves HDAC3 35
  • 81.78 (n)
  • 97.43 (a)
HDAC3 36
  • 98 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia HDAC3 36
  • 97 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia hdac3 35
  • 79.67 (n)
  • 95.56 (a)
Str.20485 35
zebrafish
(Danio rerio)
Actinopterygii hdac3 35
  • 77.8 (n)
  • 92.06 (a)
hdac3 36
  • 93 (a)
OneToOne
zgc55927 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001143 35
  • 67.45 (n)
  • 70.52 (a)
fruit fly
(Drosophila melanogaster)
Insecta Hdac3 35
  • 66.59 (n)
  • 67.06 (a)
Hdac3 36
  • 65 (a)
OneToOne
HDAC3 37
  • 65 (a)
worm
(Caenorhabditis elegans)
Secernentea hda-1 37
  • 54 (a)
hda-2 37
  • 51 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes HOS2 38
RPD3 36
  • 55 (a)
OneToMany
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.2985 35
soybean
(Glycine max)
eudicotyledons Gma.12683 35
thale cress
(Arabidopsis thaliana)
eudicotyledons HDA9 35
  • 57.77 (n)
  • 58.17 (a)
barley
(Hordeum vulgare)
Liliopsida Hv.1657 35
rice
(Oryza sativa)
Liliopsida Os04g0409600 35
  • 58.85 (n)
  • 56.54 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.837 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 70 (a)
OneToOne
Species with no ortholog for HDAC3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for HDAC3 Gene

ENSEMBL:
Gene Tree for HDAC3 (if available)
TreeFam:
Gene Tree for HDAC3 (if available)

Paralogs for HDAC3 Gene

Paralogs for HDAC3 Gene

Selected SIMAP similar genes for HDAC3 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with HDAC3: view

Variants for HDAC3 Gene

Sequence variations from dbSNP and Humsavar for HDAC3 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs250793 -- 141,631,620(+) acaga(C/T)gaaga intron-variant
rs467744 -- 141,627,929(+) CCAAT(C/G)GATCA missense, reference, utr-variant-3-prime
rs1005666 -- 141,629,627(-) GGTCT(C/T)TCAGT intron-variant
rs1882768 -- 141,633,633(-) ggtca(A/G)gctgg intron-variant
rs1882769 -- 141,633,616(-) actcc(C/T)gacct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HDAC3 Gene

Variant ID Type Subtype PubMed ID
nsv516495 CNV Gain+Loss 19592680
nsv5033 CNV Insertion 18451855

Relevant External Links for HDAC3 Gene

HapMap Linkage Disequilibrium report
HDAC3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HDAC3 Gene

Disorders for HDAC3 Gene

(1) University of Copenhagen DISEASES for HDAC3 Gene

(11) Novoseek inferred disease relationships for HDAC3 Gene

Disease -log(P) Hits PubMed IDs
colon cancer 38.1 14
cancer 31.1 12
tumors 29.3 14
colon tumor 11 1
leukemia 10.9 2

Relevant External Links for HDAC3

Genetic Association Database (GAD)
HDAC3
Human Genome Epidemiology (HuGE) Navigator
HDAC3
genes like me logo Genes that share disorders with HDAC3: view

No data available for UniProtKB/Swiss-Prot for HDAC3 Gene

Publications for HDAC3 Gene

  1. Differential display cloning of a novel human histone deacetylase (HDAC3) cDNA from PHA-activated immune cells. (PMID: 9464271) Dangond F. … Gullans S.R. (Biochem. Biophys. Res. Commun. 1998) 2 3 4 23
  2. Characterization of a human RPD3 ortholog, HDAC3. (PMID: 9501169) Emiliani S. … Verdin E. (Proc. Natl. Acad. Sci. U.S.A. 1998) 2 3 4 23
  3. Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family. (PMID: 9346952) Yang W.-M. … Seto E. (J. Biol. Chem. 1997) 3 4 23
  4. A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40- repeat protein linked to deafness. (PMID: 10809664) Guenther M.G. … Shiekhattar R. (Genes Dev. 2000) 3 4 23
  5. The histone deacetylase-3 complex contains nuclear receptor corepressors. (PMID: 10860984) Wen Y.-D. … Seto E. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 4 23

Products for HDAC3 Gene

  • Addgene plasmids for HDAC3

Sources for HDAC3 Gene

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