HDAC11 Gene
protein-coding GIFtS: 61
GCID: GC03P013496
|
|
histone deacetylase 11
| |
Aliases
for HDAC11 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Histone Deacetylase 111 2 | | HD112 3 | | EC 3.5.1.983 8 |
Export aliases for HDAC11 gene to outside databasesPrevious GC identifer: GC03P013451 |
Summaries
for HDAC11 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HDAC11:
This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involvedin regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.(providedby RefSeq, Apr 2009)
UniProtKB/Swiss-Prot: HDA11_HUMAN, Q96DB2Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B,H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptionalregulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of largemultiprotein complexes
 summary
for HDAC11: Histone Deacetylases (HDACs) are a group of enzymes closely related to sirtuins. They catalyze the removal
of acetyl groups from lysine residues in histones and non-histone proteins, resulting in transcriptional
repression. In general, they do not act autonomously but as components of large multiprotein complexes, such
as pRb-E2F and mSin3A, that mediate important transcription regulatory pathways. There are three classes of
HDACs; classes 1, 2 and 4, which are closely related Zn2+-dependent enzymes. HDACs are ubiquitously
expressed and they can exist in the nucleus or cytosol. Their subcellular localization is effected by
protein-protein interactions (for example HDAC-14.3.3 complexes are retained in the cytosol) and by the
class to which they belong (class 1 HDACs are predominantly nuclear whilst class 2 HDACs shuttle between the
nucleus and cytosol). HDACs have a role in cell growth arrest, differentiation and death and this has led to
substantial interest in HDAC inhibitors as possible antineoplastic agents.
Gene Wiki entry for HDAC11
|
Genomic Views
for HDAC11 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HDAC11 gene promoter:
SREBP-1a SREBP-1c Lmo2 CUTL1 SREBP-1b
Other transcription factors
Search SABiosciences Chromatin IP Primers for HDAC11
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HDAC11 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p25.1 Ensembl cytogenetic band: 3p25.1 HGNC cytogenetic band: 3p25.1HDAC11 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P013496: view genomic region
(about GC identifiers)
Start:
|
13,521,224 bp from pter |
End:
|
13,547,924 bp from pter |
Size:
|
26,701 bases |
Orientation:
|
plus strand |
|
Proteins
for HDAC11 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HDA11_HUMAN, Q96DB2 (See
protein sequence)Recommended Name: Histone deacetylase 11 Size: 347 amino acids; 39183 Da
Subunit: Interacts with HDAC6
Subcellular location: Nucleus. Note=Predominantly nuclear
Miscellaneous: Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor
Sequence caution: Sequence=BAB15127.1; Type=Erroneous termination; Positions=107; Note=Translated as Gln;Sequence=CAB70712.1; Type=Frameshift; Positions=177, 198, 200;
Secondary accessions: B4DDK1 Q9H6I7 Q9H6X3 Q9NTC9Alternative splicing: 2 isoforms: Q96DB2-1 Q96DB2-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for HDAC11: NX_Q96DB2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96DB2
3 DME Specific Peptides for HDAC11 (Q96DB2)
HDAC11 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001129513.1 NP_079103.2
ENSEMBL proteins: ENSP00000412514 ENSP00000295757 ENSP00000384706 ENSP00000384123 ENSP00000399792 ENSP00000385528 ENSP00000385475 ENSP00000405403 ENSP00000385252 ENSP00000384019 ENSP00000429794 ENSP00000411792 ENSP00000398651 ENSP00000402298 ENSP00000396122 ENSP00000395188 ENSP00000401487 Reactome Protein details: Q96DB2
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
HDAC11 for ontologies About GeneDecksing
HDAC11 Antibody Products:
Assay Products for HDAC11: |
Protein
Domains /
Families
for HDAC11 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HDAC11 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96DB2ProtoNet protein and cluster: Q96DB2 1 Blocks protein family: IPB000286 Histone deacetylase superfamily signature
UniProtKB/Swiss-Prot: HDA11_HUMAN, Q96DB2Similarity: Belongs to the histone deacetylase family |
Function
for HDAC11 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: HDA11_HUMAN, Q96DB2Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B,H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptionalregulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of largemultiprotein complexesCatalytic activity: Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histoneEnzyme Number (IUBMB): EC 3.5.1.981 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HDAC11 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HDAC11 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): HDAC11 (NM_001136041) | |  | Sino Biological Human cDNA Clone for HDAC11 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HDAC11 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HDAC11 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HDAC11 |
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
HDAC11 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for HDAC11:
|
Pathways & Interactions
for HDAC11 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/20 super-pathways (see all 20) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling by NOTCH1 t(7 9)(NOTCH1:M1580_K2555) Translocation Mutant | | | 2 | DNA Methylation and Transcriptional Repression | | | 3 | Cyclins and Cell Cycle Regulation | | | 4 | Disease | | | 5 | Valproic Acid Pathway, Pharmacodynamics | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for HDAC11
5/15 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for HDAC11 (see all 15)
3  BioSystems Pathways for HDAC11
5/13 
Reactome Pathways for HDAC11 (see all 13)
1  PharmGKB Pathway for HDAC11
HDAC11 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HDAC11
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/52 Interacting proteins for HDAC11 (Q96DB22, 3 ENSP000002957574) via UniProtKB, MINT, STRING, and/or I2D (see all 52)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
HDAC11 for ontologies About GeneDecksing
|
Drugs & Compounds
for HDAC11 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for HDAC11 available from Tocris Bioscience About this table
Search CenterWatch for drugs/clinical trials and news about HDAC11 / HDA11
|
Transcripts
for HDAC11 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HDAC11 gene (2 alternative transcripts): NM_001136041.2 NM_024827.3 Unigene Cluster for HDAC11: Histone deacetylase 11 Hs.744132 [show with all ESTs]Unigene Representative Sequence: NM_02482718/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21): ENST00000433119 ENST00000295757(uc010heb.3 uc003bxy.3 uc011aux.2 uc011auy.2)
ENST00000402259 ENST00000402271 ENST00000425430 ENST00000404548 ENST00000404040
ENST00000458642 ENST00000405478 ENST00000405025 ENST00000475818 ENST00000522202
ENST00000418189 ENST00000434848 ENST00000416248 ENST00000455904 ENST00000437379
ENST00000487585
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HDAC11 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HDAC11 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): HDAC11 (NM_001136041) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HDAC11 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HDAC11 |
Additional cDNA sequence: AK025426.1 AK025890.1 AK293223.1 AK299021.1 AL137362.1 AL834223.1 BC009676.1 CR457341.1 13 DOTS entries: DT.91669209 DT.120886461 DT.409141 DT.95177429 DT.91974866 DT.99979461 DT.102828195 DT.120886446 DT.95095163 DT.97778414 DT.99970847 DT.100779660 DT.120886452 24/135 AceView cDNA sequences (see all 135): BF195399 NM_024827 AK025426 BC009676 AL134619 BE856419 AA864367 BF739861 AL551256 CD515668 BM671310 AI889025 BQ928115 BF194759 AL834223 BF365978 BI520504 CR603019 CR612266 AI360857 AI672275 AW293412 BP375242 BG249632
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for HDAC11 (see all 13) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ | 15a | · | 15b | · | 15c | · | 15d |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | - | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | | | - | | | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for HDAC11
|
Expression
for HDAC11 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HDAC11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGATTTGCTG
About this image
See HDAC11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HDAC11
SOURCE GeneReport for Unigene cluster: Hs.744132
UniProtKB/Swiss-Prot: HDA11_HUMAN, Q96DB2Tissue specificity: Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney andtestis
SABiosciences Expression via Pathway-Focused PCR Arrays including HDAC11:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HDAC11
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HDAC11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HDAC11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HDAC11 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HDAC11 |
Orthologs
for HDAC11 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for HDAC11 gene from 7/22 species (see all 22) About this table
ENSEMBL Gene Tree for HDAC11 (if available)
TreeFam Gene Tree for HDAC11 (if available) |
Paralogs
for HDAC11 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for HDAC11 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HDAC11 (13521224 - 13547924 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HDAC11: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HDAC11 |
|
Disorders
/ Diseases
for HDAC11 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HDAC11 for disorders About GeneDecksing
OMIM gene information: 607226
OMIM disorders: --
10  diseases for HDAC11: About MalaCardsmeckel's diverticulum paratyphoid fever amyotrophic lateral sclerosis lateral sclerosis
inflammatory diarrhea hodgkin's lymphoma diarrhea breast cancer
pancreatitis huntington's disease
1 disease from the University of Copenhagen DISEASES database for HDAC11:Hodgkin's lymphoma Export disorders for HDAC11 gene to outside databases
|
Publications
for HDAC11 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HDAC11 gene, integrated from 9 sources (see all 29):
(articles sorted by number of sources associating them with HDAC11) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family. (PubMed id 11948178)1, 2, 3 Gao L.... Atadja P. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Mutational analyses of WNT7A and HDAC11 as candidate tumour suppressor genes in sporadic malignant pancreatic endocrine tumours. (PubMed id 17201809)1, 9 Lindberg D....Westin G. (2007)
- Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
- Increased gene expression of histone deacetylases in p atients with Philadelphia-negative chronic myeloproliferative neoplasms. (PubMed id 21806350)1 Skov V....Hasselbalch H.C. (2012)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- HDAC11 plays an essential role in regulating OX40 lig and expression in Hodgkin lymphoma. (PubMed id 21239696)1 Buglio D....Younes A. (2011)
- Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin. (PubMed id 20980834)1 Wong P.G....Alexandrow M. (2010)
|
External Searches for HDAC11 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HDAC11 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HDAC11 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HDAC11 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HDAC11 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HDAC11 gene:
Search GeneIP for patents involving HDAC11
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HDAC11 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for HDAC11 | | OriGene shRNA RFP for HDAC11 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HDAC11 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HDAC11 | | | OriGene Protein Over-expression Lysate for HDAC11 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HDAC11 | | OriGene 3'-UTR Clone for HDAC11 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HDAC11 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HDAC11 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for HDAC11 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HDAC11 | | OriGene Custom Protein Services for HDAC11 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HDAC11 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HDAC11 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HDAC11 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HDAC11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HDAC11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HDAC11 |
| |
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 |
 | | | HDAC11 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HDAC11 |
|  |  |  | | | | ThermoFisher Antibody for HDAC11 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HDAC11 |
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