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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HCN3 Gene

protein-coding   GIFtS: 59
GCID: GC01P155247

hyperpolarization activated cyclic nucleotide-gated potassium...

 Explore 5 diseases affiliated with
HCN3 via our new
 Human Malady Compendium 
Biological research products
for HCN3
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 31 2
KIAA15351 3 5
Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 32

External Ids:    HGNC: 191831   Entrez Gene: 576572   Ensembl: ENSG000001436307   OMIM: 6099735   UniProtKB: Q9P1Z33   

Export aliases for HCN3 gene to outside databases

Previous GC identifers: GC01P153105 GC01P150988 GC01P152025 GC01P152464 GC01P152060 GC01P153513 GC01P126609


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HCN3:
This gene encodes a multi-pass membrane protein that functions as a voltage gated cation channel. The encoded protein
is a member of a family of closely related cyclic adenosine monophosphate-binding channel proteins. Alternative
splicing results in multiple transcript variants. (provided by RefSeq, Aug 2012)

UniProtKB/Swiss-Prot: HCN3_HUMAN, Q9P1Z3
Function: Putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions
(By similarity)

Gene Wiki entry for HCN3


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HCN3 gene promoter:
         MAZR   POU2F1   p53   POU2F1a   ITF-2   Tal-1beta   Arnt   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHCN3 promoter sequence
   Search SABiosciences Chromatin IP Primers for HCN3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HCN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q22   Ensembl cytogenetic band:  1q22   HGNC cytogenetic band: 1q21.2

HCN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HCN3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P155247:  view genomic region     (about GC identifiers)

Start:
155,247,374 bp from pter      End:
155,259,639 bp from pter
Size:
12,266 bases      Orientation:
plus strand

1 alternative location:
Chr1+,PATCHES 155,262,764-155,275,028     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: HCN3_HUMAN, Q9P1Z3 (See protein sequence)
Recommended Name: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3  
Size: 774 amino acids; 86032 Da
Subunit: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits
Subcellular location: Membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAH28024.2; Type=Erroneous initiation;
Secondary accessions: D3DV90 Q4VX12 Q8N6W6 Q9BWQ2

Explore the universe of human proteins at neXtProt for HCN3: NX_Q9P1Z3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9P1Z3

  • HCN3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_065948.1  
    ENSEMBL proteins: 
     ENSP00000357342  
    Reactome Protein details: Q9P1Z3
    Human Recombinant Protein Products: 
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    Uscn Proteins for HCN3

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--


    HCN3 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    HCN3 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR018490 cNMP-bd-like
     IPR005821 Ion_trans_dom
     IPR000595 cNMP-bd_dom
     IPR003938 K_chnl_volt-dep_EAG/ELK/ERG
     IPR013621 Ion_trans_N

    Graphical View of Domain Structure for InterPro Entry Q9P1Z3

    ProtoNet protein and cluster: Q9P1Z3

    2 Blocks protein families:
    IPB000595 Cyclic nucleotide-binding domain
    IPB013621 Ion transport N-terminal


    UniProtKB/Swiss-Prot: HCN3_HUMAN, Q9P1Z3
    Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino
    acids at every third position
    Similarity: Belongs to the potassium channel HCN family
    Similarity: Contains 1 cyclic nucleotide-binding domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: HCN3_HUMAN, Q9P1Z3
    Function: Putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions
    (By similarity)

    miRNA
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    hsa-miR-125a-5p hsa-miR-4251 hsa-miR-218 hsa-miR-449a hsa-miR-548m hsa-miR-890 hsa-miR-125b hsa-miR-1286
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    Inhib. RNA
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005249voltage-gated potassium channel activity IEA--
    GO:0005272sodium channel activity IEA--
    GO:0005515protein binding ----
    GO:0030552cAMP binding IEA--


    HCN3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for HCN3:
     Synthetic lethal with Ras 

    Animal Models:
         Mouse knock-out Hcn3tm1.1Biel for HCN3
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Hcn3):
     cardiovascular system  nervous system 

    HCN3 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Potassium Channels
    Potassium Channels1.00
    2HCN channels
    HCN channels1.00
    3Potassium transporters: inward current
    Potassium transporters: inward current1.00
    4Sodium channels and transporters: inward current
    Sodium channels and transporters: inward current1.00
    5Transmission across Chemical Synapses
    Neuronal System0.67

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    2 EMD Millipore Pathways for HCN3
        Potassium transporters- inward current
    Sodium channels and transporters- inward current

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for HCN3
        Sperm Motility

    3        Reactome Pathways for HCN3
        Potassium Channels
    HCN channels
    Neuronal System



    HCN3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HCN3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for HCN3 (Q9P1Z33 ENSP000003573424) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HCN1O607413, ENSP000003073424I2D: score=1 STRING: ENSP00000307342
    HCN4Q9Y3Q43, ENSP000002619174I2D: score=1 STRING: ENSP00000261917
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007268synaptic transmission TAS--


    HCN3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HCN3

    2 HMDB Compounds for HCN3    About this table
    CompoundSynonyms CAS #PubMed Ids
    Cyclic AMPCyclic AMP (see all 19)60-92-4--
    SodiumSodium (see all 2)7440-23-5--
    Search CenterWatch for drugs/clinical trials and news about HCN3 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HCN3 gene: 
    NM_020897.2  

    Unigene Cluster for HCN3:

    Hyperpolarization activated cyclic nucleotide-gated potassium channel 3
    Hs.706960  [show with all ESTs]
    Unigene Representative Sequence: NM_020897
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368358(uc010pfz.1 uc001fjz.1) ENST00000496230 ENST00000467204
    ENST00000492035

    miRNA
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    hsa-miR-125a-5p hsa-miR-4251 hsa-miR-218 hsa-miR-449a hsa-miR-548m hsa-miR-890 hsa-miR-125b hsa-miR-1286
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    Additional cDNA sequence: 

    AB040968.2 AF488550.1 AK055840.1 AK299333.1 BC000066.1 BC028024.1 NR_073074.1 

    6 DOTS entries:

    DT.453928  DT.121427749  DT.102842511  DT.91841171  DT.100718953  DT.121427760 

    24/47 AceView cDNA sequences (see all 47):

    BQ070889 AL559044 AK055840 BM713434 NM_020897 BI063704 CR625647 AB040968 
    AA384187 BM693435 AW243139 CA428857 AA665929 BC028024 BU167626 AI457329 
    BE260963 BE793179 AA569834 BI918260 BQ448299 AW001103 BC000066 AF488550 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for HCN3    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11
    SP1:                                      -                                                               
    SP2:                                            -                       -                                 
    SP3:        -                                                                                             
    SP4:                                                                    -                                 
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for HCN3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HCN3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGAGAGGGAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See HCN3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HCN3

    SOURCE GeneReport for Unigene cluster: Hs.706960
        SABiosciences Custom PCR Arrays for HCN3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HCN3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for HCN3 gene from 4/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    zebrafish
    (Danio rerio)
    Actinopterygii CABZ01100328.16
    hcn36
    (see all 3)
    --
    hyperpolarization activated cyclic nucleotide-gate...
    (see all 3)
    84(a)
    60(a)
    (see all 3)
    1 ↔ many
    1 ↔ many
    (see all 3)
    16(58083121-58086192)
    19(9808711-9832437)
    fruit fly
    (Drosophila melanogaster)
    Insecta Ih1 I[[h]] channel 62.15(n)
    60.88(a)
      36589  NM_001144196.2  NP_001137668.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SPIK6
    ATCNGC146
    (see all 29)
    cyclic nucleotide gated channel
    (see all 29)
    9(a)
    15(a)
    (see all 29)
    possible ortholog
    possible ortholog
    (see all 29)
    2(10894486-10898642)
    2(10457045-10460508)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 28)
    potassium channel AKT1, putative, expressed
    cyclic nucleotide-gated ion channel 1, putative, e...
    (see all 28)
    9(a)
    19(a)
    (see all 28)
    possible ortholog
    possible ortholog
    (see all 28)
    1(26118664-26125121)
    6(19563212-19568252)


    ENSEMBL Gene Tree for HCN3 (if available)
    TreeFam Gene Tree for HCN3 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HCN3 gene
    KCNH62  KCNH32  KCNH52  HCN42  HCN22  KCNH42  CNGA22  CNGA12  
    HCN12  KCNH72  KCNH22  CNGB12  CNGA42  CNGA32  CNGB32  KCNH12  
    KCNH82  
    4 SIMAP similar genes for HCN3 using alignment to 3 protein entries:     HCN3_HUMAN (see all proteins):
    HCN4    HCN2    HCN1    KCNH2

    HCN3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/229 NCBI SNPs in HCN3 are shown (see all 229    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1834271221,2
    --155245303(+) AAAAAA/GAAAAA 2 -- us2k10--------
    rs101280851,2
    C,F,A,--155245318(+) AGAAAG/AGAAAA 2 -- us2k1 tfbs3 trp36Minor allele frequency- A:0.18NA WA CSA 11
    rs2002737771,2
    --155245340(+) GAAAG-/AGAA  
            
    AGAGT
    2 -- us2k10--------
    rs563704091,2
    C--155245404(+) GAGAAA/GTAATA 2 -- us2k10--------
    rs1879691821,2
    --155245524(+) GGGTCA/GTGATC 2 -- us2k10--------
    rs1428101511,2
    --155245621(+) AGCTGG/TATGAA 2 -- us2k10--------
    rs1412456931,2
    --155245748(+) TTCCA-/CCTCCTGG 2 -- us2k10--------
    rs1442858891,2
    --155245765(+) TTTTCC/TTAGAT 2 -- us2k10--------
    rs1910416631,2
    --155245926(+) AGCACA/TTTGGG 2 -- us2k10--------
    rs1483328131,2
    --155245936(+) GAAGCC/TAAGGC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for HCN3 (155247374 - 155259639 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 6 variations for HCN3
         6 CNVs: 0396 3315 65020 4257 34720 6789

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HCN3
    DNA2.0 Custom Variant and Variant Library Synthesis for HCN3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    HCN3 for disorders           About GeneDecksing

    OMIM gene information: 609973    OMIM disorders: --

    5 diseases for HCN3:    About MalaCards
    pallister-hall syndrome    diabetic autonomic neuropathy    autonomic neuropathy    neuropathy
    neuronitis

    3 diseases from the University of Copenhagen DISEASES database for HCN3:
    Pallister-Hall syndrome     Sick sinus syndrome     Diabetic autonomic neuropathy

    Export disorders for HCN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HCN3 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with HCN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    2. International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels. (PubMed id 16382102)1, 3 Hofmann F....Kaupp U.B. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2 Nagase T.... Ohara O. (2000)
    5. An interactive tool for extracting exons and SNP from genomic sequence: isolation of HCN1 and HCN3 ion channel genes. (PubMed id 15290763)1, 9 Liu Y....Blevins R. (2003)
    6. Endogenous channels in HEK cells and potential roles in HCN ionic current measurements. (PubMed id 15979128)1, 9 Varghese A....Sigg D.C. (2006)
    7. Genetic analysis of hyperpolarization-activated cycli c nucleotide-gated cation channels in sudden unexpected death in epilepsy cases . (PubMed id 21615589)1 Tu E....Semsarian C. (2011)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. Functional expression of the human HCN3 channel. (PubMed id 16043489)1 Stieber J....Hofmann F. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57657 HGNC: 19183 AceView: HCN3 Ensembl:ENSG00000143630 euGenes: HUgn57657
    ECgene: HCN3 H-InvDB: HCN3

    (According to HUGE)
    About This Section
    HUGE: KIAA1535

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HCN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HCN3 gene:
    Search GeneIP for patents involving HCN3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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