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Aliases for HCG22 Gene

Aliases for HCG22 Gene

  • HLA Complex Group 22 2 3 4
  • HLA Complex Group 22 (Non-Protein Coding) 2 3
  • Panbronchiolitis Related Mucin-Like 2 2 3
  • PBMUCL2 3 4
  • Panbronchiolitis-Related Mucin-Like Protein 2 4
  • G2 4

External Ids for HCG22 Gene

Previous GeneCards Identifiers for HCG22 Gene

  • GC06U900708
  • GC06P031129
  • GC06Pf31157
  • GC06P031022

Summaries for HCG22 Gene

GeneCards Summary for HCG22 Gene

HCG22 (HLA Complex Group 22) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HCG22 Gene

Genomics for HCG22 Gene

Regulatory Elements for HCG22 Gene

Genomic Location for HCG22 Gene

Chromosome:
6
Start:
31,053,450 bp from pter
End:
31,059,890 bp from pter
Size:
6,441 bases
Orientation:
Plus strand

Genomic View for HCG22 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HCG22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for HCG22 Gene

  • Protein details for HCG22 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    E2RYF7-PBMU2_HUMAN
    Recommended name:
    Protein PBMUCL2
    Protein Accession:
    E2RYF7

    Protein attributes for HCG22 Gene

    Size:
    251 amino acids
    Molecular mass:
    26282 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HCG22 Gene

Proteomics data for HCG22 Gene at MOPED

Post-translational modifications for HCG22 Gene

No data available for DME Specific Peptides for HCG22 Gene

Domains & Families for HCG22 Gene

Protein Domains for HCG22 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for HCG22 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HCG22: view

No data available for Gene Families and UniProtKB/Swiss-Prot for HCG22 Gene

Function for HCG22 Gene

Phenotypes for HCG22 Gene

GenomeRNAi human phenotypes for HCG22:
genes like me logo Genes that share phenotypes with HCG22: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HCG22 Gene

Localization for HCG22 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HCG22 Gene

Secreted.

Gene Ontology (GO) - Cellular Components for HCG22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with HCG22: view

No data available for Subcellular locations from COMPARTMENTS for HCG22 Gene

Pathways & Interactions for HCG22 Gene

SuperPathways for HCG22 Gene

No Data Available

Interacting Proteins for HCG22 Gene

Gene Ontology (GO) - Biological Process for HCG22 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HCG22 Gene

Drugs & Compounds for HCG22 Gene

No Compound Related Data Available

Transcripts for HCG22 Gene

mRNA/cDNA for HCG22 Gene

(4) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HCG22 Gene

HLA complex group 22 (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HCG22 Gene

No ASD Table

Relevant External Links for HCG22 Gene

GeneLoc Exon Structure for
HCG22
ECgene alternative splicing isoforms for
HCG22

Expression for HCG22 Gene

mRNA expression in normal human tissues for HCG22 Gene

mRNA differential expression in normal tissues according to GTEx for HCG22 Gene

This gene is overexpressed in Vagina (x20.5), Esophagus - Mucosa (x11.7), Cervix - Ectocervix (x8.2), and Minor Salivary Gland (x4.5).

SOURCE GeneReport for Unigene cluster for HCG22 Gene Hs.207528

mRNA Expression by UniProt/SwissProt for HCG22 Gene

E2RYF7-PBMU2_HUMAN
Tissue specificity: Detected in the brain, lung, spleen, thymus and prostate.
genes like me logo Genes that share expression patterns with HCG22: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for HCG22 Gene

Orthologs for HCG22 Gene

Evolution for HCG22 Gene

ENSEMBL:
Gene Tree for HCG22 (if available)
TreeFam:
Gene Tree for HCG22 (if available)

No data available for Orthologs for HCG22 Gene

Paralogs for HCG22 Gene

No data available for Paralogs for HCG22 Gene

Variants for HCG22 Gene

Sequence variations from dbSNP and Humsavar for HCG22 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs207466849 Uncertain significance, Uncertain significance 31,052,226(+) CTATG(C/T)AAGAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for HCG22 Gene

Variant ID Type Subtype PubMed ID
esv2731791 CNV Deletion 23290073
esv2670269 CNV Deletion 23128226
dgv6536n71 CNV Loss 21882294
nsv884132 CNV Loss 21882294
esv27565 CNV Loss 19812545
nsv511865 CNV Loss 21212237
esv4161 CNV Deletion 18987735
esv2731805 CNV Deletion 23290073
nsv524716 CNV Loss 19592680
esv2731808 CNV Deletion 23290073
esv2731809 CNV Deletion 23290073
nsv884133 CNV Loss 21882294

Relevant External Links for HCG22 Gene

HapMap Linkage Disequilibrium report
HCG22

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HCG22 Gene

Disorders for HCG22 Gene

Relevant External Links for HCG22

Genetic Association Database (GAD)
HCG22
Human Genome Epidemiology (HuGE) Navigator
HCG22
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HCG22
genes like me logo Genes that share disorders with HCG22: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HCG22 Gene

Publications for HCG22 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 67
  2. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. (PMID: 25429064) He M. … Qi L. (Hum. Mol. Genet. 2015) 67
  3. GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. (PMID: 23263863) Li J. … Sleiman P.M. (Hum. Mol. Genet. 2013) 67
  4. Novel associations for hypothyroidism include known autoimmune risk loci. (PMID: 22493691) Eriksson N. … Do C.B. (PLoS ONE 2012) 67
  5. Identification of a susceptibility locus in STAT4 for BehAset's disease in Han Chinese in a genome-wide association study. (PMID: 23001997) Hou S. … Yang P. (Arthritis Rheum. 2012) 67

Products for HCG22 Gene

Sources for HCG22 Gene

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