Free for academic non-profit institutions. Other users need a Commercial license

Aliases for HCG18 Gene

Subcategory (RNA class) for HCG18 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for HCG18 Gene

  • HLA Complex Group 18 (Non-Protein Coding) 2 3 5
  • HLA Complex Group 18 2

External Ids for HCG18 Gene

Previous GeneCards Identifiers for HCG18 Gene

  • GC00U915705
  • GC06U900759
  • GC06M030259
  • GC06M030053

Summaries for HCG18 Gene

GeneCards Summary for HCG18 Gene

HCG18 (HLA Complex Group 18 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HCG18 Gene

Genomics for HCG18 Gene

Regulatory Elements for HCG18 Gene

Enhancers for HCG18 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F030907 1.2 ENCODE 86.3 -581.3 -581302 2.2 CREB3L1 YBX1 DMAP1 YY1 ZNF416 ZNF143 ZNF548 ZNF263 SP3 NFYC HCG18 GTF2H4 DDX39B LY6G5B DHX16 ABCF1 VARS2 LSM2 PPP1R10 NFKBIL1
GH06F030162 1.1 ENCODE 87.4 +163.4 163391 2.8 HDGF PKNOX1 ARNT ZFP64 SIN3A ARID4B FEZF1 DMAP1 ZNF2 YY1 HCG18 GTF2H4 PPP1R10 ETF1P1 DHX16 PAIP1P1 HLA-U ZNRD1ASP HCG4P7 TCF19
GH06F030194 1.1 ENCODE 85.8 +131.8 131829 1.6 ZFP64 ARID4B DMAP1 YY1 SLC30A9 ZNF302 SP3 SP5 MXD4 ZHX2 HCG18 GTF2H4 PPP1R10 ETF1P1 DHX16 PAIP1P1 ZNRD1ASP HCG4P7 TRIM31 GNL1
GH06F030939 1.2 ENCODE 51.8 -613.5 -613473 1.5 CREB3L1 ZFP64 FEZF1 DMAP1 YBX1 YY1 SLC30A9 ZNF143 ZNF416 ZNF548 GTF2H4 HCG18 LSM2 NFKBIL1 PPP1R10 DDX39B LY6G5B MICA PAIP1P1 ZNRD1ASP
GH06F030816 1.8 FANTOM5 Ensembl ENCODE 25 -492.8 -492845 6.8 HDGF PKNOX1 ARNT MLX ARID4B SLC30A9 ZNF143 FOS KLF13 SP5 IER3 DDR1 HCG18 PRR3 RPP21 PPP1R10 HLA-E PPP1R18 FLOT1 LINC00243
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HCG18 on UCSC Golden Path with GeneCards custom track

Promoters for HCG18 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000487631 656 3001 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 SLC30A9

Genomic Location for HCG18 Gene

Chromosome:
6
Start:
30,287,397 bp from pter
End:
30,327,156 bp from pter
Size:
39,760 bases
Orientation:
Minus strand

Genomic View for HCG18 Gene

Genes around HCG18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HCG18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HCG18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for HCG18 Gene

Post-translational modifications for HCG18 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HCG18 Gene

Domains & Families for HCG18 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HCG18 Gene

Function for HCG18 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HCG18 Gene

Localization for HCG18 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HCG18 Gene

Pathways & Interactions for HCG18 Gene

SuperPathways for HCG18 Gene

No Data Available

Interacting Proteins for HCG18 Gene

Gene Ontology (GO) - Biological Process for HCG18 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HCG18 Gene

Transcripts for HCG18 Gene

mRNA/cDNA for HCG18 Gene

(9) Additional mRNA sequences :
(16) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HCG18 Gene

HLA complex group 18 (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HCG18 Gene

No ASD Table

Relevant External Links for HCG18 Gene

GeneLoc Exon Structure for
HCG18
ECgene alternative splicing isoforms for
HCG18

Expression for HCG18 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HCG18 Gene

NURSA nuclear receptor signaling pathways regulating expression of HCG18 Gene:

HCG18

SOURCE GeneReport for Unigene cluster for HCG18 Gene:

Hs.485041
genes like me logo Genes that share expression patterns with HCG18: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for HCG18 Gene

Orthologs for HCG18 Gene

Evolution for HCG18 Gene

ENSEMBL:
Gene Tree for HCG18 (if available)
TreeFam:
Gene Tree for HCG18 (if available)

No data available for Orthologs for HCG18 Gene

Paralogs for HCG18 Gene

No data available for Paralogs for HCG18 Gene

Variants for HCG18 Gene

Sequence variations from dbSNP and Humsavar for HCG18 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs10428749 -- 30,323,433(+) gcaaa(A/G)gctgt intron-variant
rs1045251 -- 30,291,880(-) CTGAG(A/C)CTCCC intron-variant, nc-transcript-variant
rs10484551 -- 30,289,061(+) GTAAC(A/G)GTAGT intron-variant, nc-transcript-variant
rs1048664 -- 30,294,735(-) TGGGC(C/T)TGAGA intron-variant, nc-transcript-variant
rs10713273 -- 30,292,318(+) GTGGG(-/T)TTTTT intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for HCG18 Gene

Variant ID Type Subtype PubMed ID
esv3411275 CNV duplication 20981092
nsv1074389 CNV deletion 25765185
nsv1122126 CNV deletion 24896259
nsv1144137 CNV deletion 24896259
nsv601264 CNV loss 21841781

Relevant External Links for HCG18 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HCG18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HCG18 Gene

Disorders for HCG18 Gene

Relevant External Links for HCG18

Genetic Association Database (GAD)
HCG18
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HCG18

No disorders were found for HCG18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HCG18 Gene

Publications for HCG18 Gene

  1. Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with BehAset's disease. (PMID: 20622878) Remmers E.F. … GA1l A. (Nat. Genet. 2010) 46 64
  2. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PMID: 19010793) Baranzini S.E. … Oksenberg J.R. (Hum. Mol. Genet. 2009) 46 64
  3. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. (PMID: 18204098) Hom G. … Behrens T.W. (N. Engl. J. Med. 2008) 46 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for HCG18 Gene

Sources for HCG18 Gene

Content
Loading form....