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Aliases for HCG18 Gene

Subcategory (RNA class) for HCG18 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for HCG18 Gene

  • HLA Complex Group 18 (Non-Protein Coding) 2 3 5
  • HLA Complex Group 18 2

External Ids for HCG18 Gene

Previous GeneCards Identifiers for HCG18 Gene

  • GC00U915705
  • GC06U900759
  • GC06M030259
  • GC06M030053

Summaries for HCG18 Gene

GeneCards Summary for HCG18 Gene

HCG18 (HLA Complex Group 18 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HCG18 Gene

Genomics for HCG18 Gene

Regulatory Elements for HCG18 Gene

Enhancers for HCG18 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G030324 1.4 ENCODE dbSUPER 41.2 +0.7 729 3.5 HDGF PKNOX1 CREB3L1 ARNT ARID4B SIN3A YBX1 FEZF1 DMAP1 ZNF2 HCG18 HCG17 RPL23AP1 MICD GABBR1 HLA-E GTF2H4 ZNRD1ASP GNL1 ZFP57
GH06G031137 1.3 Ensembl ENCODE 44 -810.5 -810546 0.6 HDGF PKNOX1 ATF1 ARNT ZNF493 ARID4B DMAP1 ZNF2 ZNF48 ZNF121 HCG18 LSM2 LY6G5B NFKBIL1 GTF2H4 PSORS1C2 DDX39B ATF6B PSORS1C1 RPL3P2
GH06G030907 1.2 ENCODE 44.3 -581.3 -581302 2.2 CREB3L1 DMAP1 YBX1 YY1 ZNF416 ZNF143 ZNF548 ZNF263 SP3 NFYC VARS2 GTF2H4 DHX16 HCG18 LY6G5B DDX39B LSM2 ABCF1 ETF1P1 PAIP1P1
GH06G030162 1.1 ENCODE 45.9 +163.4 163391 2.8 HDGF PKNOX1 ARNT ZFP64 SIN3A ARID4B DMAP1 FEZF1 ZNF2 YY1 HCG18 HLA-U GTF2H4 HCG4P7 ZNRD1ASP CCHCR1 PPP1R10 ETF1P1 TCF19 TRIM26
GH06G030194 1.1 ENCODE 44.1 +131.8 131829 1.6 ZFP64 ARID4B DMAP1 YY1 SLC30A9 ZNF302 SP3 SP5 MXD4 ZHX2 HCG18 GTF2H4 TRIM31 HCG4P7 GNL1 ZNRD1ASP CCHCR1 PPP1R10 ETF1P1 TCF19
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HCG18 on UCSC Golden Path with GeneCards custom track

Promoters for HCG18 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000195385 656 2201 HDGF PKNOX1 CREB3L1 ARNT ARID4B SIN3A YBX1 FEZF1 DMAP1 ZNF2

Genomic Location for HCG18 Gene

Chromosome:
6
Start:
30,287,397 bp from pter
End:
30,327,156 bp from pter
Size:
39,760 bases
Orientation:
Minus strand

Genomic View for HCG18 Gene

Genes around HCG18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HCG18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HCG18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for HCG18 Gene

Post-translational modifications for HCG18 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HCG18 Gene

Domains & Families for HCG18 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HCG18 Gene

Function for HCG18 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HCG18 Gene

Localization for HCG18 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HCG18 Gene

Pathways & Interactions for HCG18 Gene

SuperPathways for HCG18 Gene

No Data Available

Interacting Proteins for HCG18 Gene

Gene Ontology (GO) - Biological Process for HCG18 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HCG18 Gene

Drugs & Compounds for HCG18 Gene

No Compound Related Data Available

Transcripts for HCG18 Gene

mRNA/cDNA for HCG18 Gene

(9) Additional mRNA sequences :
(16) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HCG18 Gene

HLA complex group 18 (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HCG18 Gene

No ASD Table

Relevant External Links for HCG18 Gene

GeneLoc Exon Structure for
HCG18
ECgene alternative splicing isoforms for
HCG18

Expression for HCG18 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HCG18 Gene

NURSA nuclear receptor signaling pathways regulating expression of HCG18 Gene:

HCG18

SOURCE GeneReport for Unigene cluster for HCG18 Gene:

Hs.485041
genes like me logo Genes that share expression patterns with HCG18: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HCG18 Gene

Orthologs for HCG18 Gene

Evolution for HCG18 Gene

ENSEMBL:
Gene Tree for HCG18 (if available)
TreeFam:
Gene Tree for HCG18 (if available)

No data available for Orthologs for HCG18 Gene

Paralogs for HCG18 Gene

No data available for Paralogs for HCG18 Gene

Variants for HCG18 Gene

Sequence variations from dbSNP and Humsavar for HCG18 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000078658 -- 30,298,192(+) AGGGA(C/T)TGCTG intron-variant
rs1000187876 -- 30,310,481(+) GAGAC(A/C)ATCCT intron-variant
rs1000247515 -- 30,327,440(+) CTCTC(A/G)GGAGA intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1000317461 -- 30,299,731(+) TATGT(C/T)GGCTT intron-variant
rs1000348443 -- 30,299,524(+) GAGTT(C/T)TCTAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HCG18 Gene

Variant ID Type Subtype PubMed ID
esv3411275 CNV duplication 20981092
nsv1074389 CNV deletion 25765185
nsv1122126 CNV deletion 24896259
nsv1144137 CNV deletion 24896259
nsv601264 CNV loss 21841781

Relevant External Links for HCG18 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HCG18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HCG18 Gene

Disorders for HCG18 Gene

Relevant External Links for HCG18

Genetic Association Database (GAD)
HCG18
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HCG18

No disorders were found for HCG18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HCG18 Gene

Publications for HCG18 Gene

  1. Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with BehAset's disease. (PMID: 20622878) Remmers E.F. … GA1l A. (Nat. Genet. 2010) 46 64
  2. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PMID: 19010793) Baranzini S.E. … Oksenberg J.R. (Hum. Mol. Genet. 2009) 46 64
  3. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. (PMID: 18204098) Hom G. … Behrens T.W. (N. Engl. J. Med. 2008) 46 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for HCG18 Gene

Sources for HCG18 Gene

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