HCCS Gene
protein-coding GIFtS: 61
GCID: GC0XP011039
|
|
holocytochrome c synthase(Previous name: holocytochrome c synthase (cytochrome c heme-lyase) )
| |
Aliases
for HCCS gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Holocytochrome C Synthase1 2 | | MCOPS72 5 | | CCHL1 2 3 | | Holocytochrome C Synthase (Cytochrome C Heme-Lyase)1 | | Holocytochrome C-Type Synthase2 3 | | Cytochrome C Heme-Lyase2 | | EC 4.4.1.173 8 | | Cytochrome C-Type Heme Lyase2 |
Export aliases for HCCS gene to outside databasesPrevious GC identifers: GC0XP010108 GC0XP009895 GC0XP010425 GC0XP010490 GC0XP010889 GC0XP008910 |
Summaries
for HCCS gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HCCS:
The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c.Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding thesame protein have been found for this gene. (provided by RefSeq, Jan 2010)
UniProtKB/Swiss-Prot: CCHL_HUMAN, P53701Function: Links covalently the heme group to the apoprotein of cytochrome c (By similarity)
Gene Wiki entry for HCCS
|
Genomic Views
for HCCS gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_167197.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HCCS gene promoter:
FOXD3 HNF-3beta MEF-2A AREB6 PPAR-gamma1 GATA-6 POU2F1 POU2F1a aMEF-2 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for HCCS
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HCCS |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp22.3 Ensembl cytogenetic band: Xp22.2 HGNC cytogenetic band: Xp22HCCS Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP011039: view genomic region
(about GC identifiers)
Start:
|
11,129,406 bp from pter |
End:
|
11,141,206 bp from pter |
Size:
|
11,801 bases |
Orientation:
|
plus strand |
|
Proteins
for HCCS gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CCHL_HUMAN, P53701 (See
protein sequence)Recommended Name: Cytochrome c-type heme lyase Size: 268 amino acids; 30602 Da
Subcellular location: Mitochondrion inner membrane (Potential)
Secondary accessions: B3KUS1 Q502X8Explore the universe of human proteins at neXtProt for HCCS: NX_P53701
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P53701
4 DME Specific Peptides for HCCS (P53701)
HCCS Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001116080.1 NP_001165462.1 NP_005324.3
ENSEMBL proteins: ENSP00000326579 ENSP00000370140 ENSP00000370139
Human Recombinant Protein Products for HCCS:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
IDA | -- | | GO:0005743 | mitochondrial inner membrane |
IEA | -- |
HCCS for ontologies About GeneDecksing
HCCS Antibody Products:
Assay Products for HCCS: |
Protein
Domains /
Families
for HCCS gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HCCS for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P53701ProtoNet protein and cluster: P53701 1 Blocks protein family: IPB000511 Cytochrome c and c1 heme-lyase
UniProtKB/Swiss-Prot: CCHL_HUMAN, P53701Similarity: Belongs to the cytochrome c-type heme lyase familySimilarity: Contains 2 HRM (heme regulatory motif) repeats |
Function
for HCCS gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: CCHL_HUMAN, P53701Function: Links covalently the heme group to the apoprotein of cytochrome c (By similarity)Catalytic activity: Holocytochrome c = apocytochrome c + heme Genatlas biochemistry entry for HCCS:holocytochrome C-type synthetase,putatively involved in electron transport pathway
Enzyme Number (IUBMB): EC 4.4.1.171 2
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004408 | holocytochrome-c synthase activity |
IEA | -- | | GO:0046872 | metal ion binding |
IEA | -- |
HCCS for ontologies About GeneDecksing
Phenotypes:
8 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Hccs):
HCCS for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HCCS (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HCCS (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): HCCS (NM_005333) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HCCS | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HCCS |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HCCS |
|
Pathways & Interactions
for HCCS gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Glucuronidation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for HCCS):
HCCS for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HCCS
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/42 Interacting proteins for HCCS (P537013 ENSP000003265794) via UniProtKB, MINT, STRING, and/or I2D (see all 42)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
HCCS for ontologies About GeneDecksing
|
Drugs & Compounds
for HCCS gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HCCS
2 HMDB Compounds for HCCS About this table
Search CenterWatch for drugs/clinical trials and news about HCCS / CCHL
|
Transcripts
for HCCS gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HCCS gene (3 alternative transcripts): NM_001122608.2 NM_001171991.2 NM_005333.4 Unigene Cluster for HCCS: Holocytochrome c synthase Hs.211571 [show with all ESTs]Unigene Representative Sequence: NM_0053333 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000321143(uc004cul.2 uc004cuk.3 uc004cuj.3) ENST00000380763
ENST00000380762
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HCCS (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HCCS (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): HCCS (NM_005333) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HCCS | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HCCS |
Additional cDNA sequence: AF143324.1 AK097815.1 BC001691.2 BC095455.1 CR749578.1 U36787.1 7 DOTS entries: DT.100822164 DT.95162995 DT.100822162 DT.441375 DT.121283626 DT.100822160 DT.100822169 24/142 AceView cDNA sequences (see all 142): BP372370 AA310250 AI801013 AI767240 BQ014124 CK904880 BM459978 CD369170 BQ013047 BM980388 AL561481 AW444785 AI674435 BE504530 AK097815 CB306404 CB160415 CR594352 CR615500 BQ000137 BC001691 AI222717 C02260 BM055275
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for HCCS About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c |
|---|
|
| SP1: | | | | | - | | - | | - | | | | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | | | | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for HCCS
|
Expression
for HCCS gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HCCS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGCAGAGTG
About this image
See HCCS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HCCS
SOURCE GeneReport for Unigene cluster: Hs.211571
SABiosciences Custom PCR Arrays for HCCS
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HCCS
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HCCS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HCCS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HCCS | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HCCS |
Orthologs
for HCCS gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals and fungi.
Orthologs for HCCS gene from 8/33 species (see all 33) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Hccs1 , 5 |
holocytochrome c synthetase1, 5 |
85.2(n)1
85.45(a)1 |
|
X (78.98 cM)5
151591 NM_008222.41 NP_032248.31
1692501935 |
chicken
(Gallus gallus) |
Aves |
HCCS1 |
holocytochrome c synthase |
75.41(n)
77.15(a) |
|
424482 NM_001031275.1 NP_001026446.1 |
lizard
(Anolis carolinensis) |
Reptilia |
HCCS6 |
-- |
78(a) |
1 ↔ 1 |
4(89515906-89533461) |
African clawed frog
(Xenopus laevis) |
Amphibia |
hccs-prov2 |
holocytochrome c synthase (cytochrome c heme-lyase) |
81.78(n) |
|
BC045005.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.44232 |
Danio rerio mRNA similar to holocytochrome c synthetase more |
77.84(n) |
|
BC044486.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG60223 |
holocytochrome c synthase |
53(a) |
|
93F13 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
T06D8.63 |
cyctochrome c1 heme lyase |
58(a) |
|
II(11235241-11236278) -- |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
CYC3(YAL039C)4
CYT21 |
Cytochrome c heme lyase (holocytochrome c synthase), more4
Cyt2p1 |
51.39(n)1
43.45(a)1 |
|
1(69525-68716)4
8537751 NP_012836.11 8511924
NP_009361.14 |
ENSEMBL Gene Tree for HCCS (if available)
TreeFam Gene Tree for HCCS (if available) |
Paralogs
for HCCS gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for HCCS gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HCCS (11129406 - 11141206 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HCCS: --
Human Gene Mutation Database (HGMD): HCCS
Locus Specific Mutation Databases (LSDB): HCCS
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HCCS |
|
Disorders
/ Diseases
for HCCS gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HCCS for disorders About GeneDecksing
OMIM gene information: 300056
OMIM disorders: 309801
UniProtKB/Swiss-Prot: CCHL_HUMAN, P53701
Defects in HCCS are a cause of microphthalmia syndromic type 7 (MCOPS7) [MIM:309801]; also known asmicrophthalmia with linear skin defects (MLS) or MIDAS syndrome. Microphthalmia is a clinically heterogeneous disorderof eye formation, ranging from small size of a single eye TO complete bilateral absence of ocular tissues(anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that includenon-ocular abnormalities. MCOPS7 is a disorder characterized by unilateral or bilateral microphthalmia, linear skindefects in affected females, and in utero lethality for males. Skin defects are limited to the face and neck,consisting of areas of aplastic skin that heal with age to form hyperpigmented areas. Additional features in femalepatients include agenesis of the corpus callosum, sclerocornea, chorioretinal abnormalities, infantile seizures,congenital heart defect, mental retardation, and diaphragmatic hernia
17  diseases for HCCS: About MalaCardsmicrophthalmia microphthalmia with linear skin defects focal dermal hypoplasia microphthalmia syndromic 7
congenital diaphragmatic hernia corpus callosum ocular albinism x inactivation
pyelonephritis barth syndrome chronic pyelonephritis albinism
chorioretinitis hernia rett syndrome anophthalmia
malaria
1 disease from the University of Copenhagen DISEASES database for HCCS:Microphthalmia 1 Novoseek disease relationship for HCCS gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| microphthalmia |
87.7 |
4 |
17893649 (1), 9674913 (1), 15576047 (1), 8661044 (1) |
GeneTests: HCCS
Microphthalmia with Linear Skin Defects Syndrome
Export disorders for HCCS gene to outside databases
|
Publications
for HCCS gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HCCS gene, integrated from 9 sources (see all 32):
(articles sorted by number of sources associating them with HCCS) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mutations of the mitochondrial holocytochrome c-type synthase in X- linked dominant microphthalmia with linear skin defects syndrome. (PubMed id 17033964)1, 2, 9 Wimplinger I.... Kutsche K. (2006)
- Cloning and characterization of a putative human holocytochrome c- type synthetase gene (HCCS) isolated from the critical region for microphthalmia with linear skin defects (MLS). (PubMed id 8661044)1, 2, 9 Schaefer L.... Zoghbi H.Y. (1996)
- Genomic structure of a human holocytochrome c-type synthetase gene in Xp22.3 and mutation analysis in patients with Rett syndrome. (PubMed id 9674913)1, 2, 9 van den Veyver I.B.... Zoghbi H.Y. (1998)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Complementation of a yeast CYC3 deficiency identifies an X-linked mammalian activator of apocytochrome c. (PubMed id 11827457)1, 9 Schwarz Q.P. and Cox T.C. (2002)
- HCCS loss-of-function missense mutation in a female with bilateral microphthalmia and sclerocornea: a novel gene for severe ocular malformations? (PubMed id 17893649)1, 9 Wimplinger I....Kutsche K. (2007)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- A genome-wide study of common SNPs and CNVs in cognit ive performance in the CANTAB. (PubMed id 19734545)1 Need A.C....Goldstein D.B. (2009)
|
External Searches for HCCS gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HCCS gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HCCS gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HCCS gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HCCS | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/HCCS |
|
| | |
About This Section
| Patent Information for HCCS gene:
Search GeneIP for patents involving HCCS
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HCCS gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for HCCS | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HCCS | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HCCS | | | OriGene Protein Over-expression Lysate for HCCS | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HCCS | | OriGene 3'-UTR Clone for HCCS | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HCCS | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HCCS | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for HCCS | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HCCS | | OriGene Custom Protein Services for HCCS | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HCCS | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HCCS | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HCCS | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HCCS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HCCS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HCCS |
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| | | | Search Tocris compounds for HCCS |
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 | | | HCCS Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HCCS |
|  |  |  |  | | | | ThermoFisher Antibody for HCCS |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HCCS |
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