Aliases for HCAR3 Gene
External Ids for HCAR3 Gene
Previous HGNC Symbols for HCAR3 Gene
Previous GeneCards Identifiers for HCAR3 Gene
GeneCards Summary for HCAR3 Gene
HCAR3 (Hydroxycarboxylic Acid Receptor 3) is a Protein Coding gene. Diseases associated with HCAR3 include distal hereditary motor neuropathy, type ii. Among its related pathways are cAMP signaling pathway and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is HCAR1.
UniProtKB/Swiss-Prot for HCAR3 Gene
Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.