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HBXIP Gene

protein-coding GIFtS: 54

GC01M110655

hepatitis B virus x interacting protein
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
MGC71071 ^¹, ²
XIP ^¹, ², ³

Descriptions
HBV X-interacting protein ^³
HBX-interacting protein ^², ³
hepatitis B virus x interacting protein ^²
hepatitis B virus x-interacting protein ^²
hepatitis B virus x-interacting protein (9.6kD) ^²

External Ids
HGNC: 17955¹
Entrez Gene: 10542²
UniProtKB: O43504³
Ensembl: ENSG00000134248⁷

Search outside databases for aliases for HBXIP gene

Previous GC identifers: GC01M111360 GC01M109810 GC01M110045 GC01M110242

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for HBXIP:

This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X

protein (HBx). The function of this protein is to negatively regulate HBx activity and thus to

alter the replication life cycle of the virus. [provided by RefSeq]

UniProtKB/Swiss-Prot: HBXIP_HUMAN, O43504

Function: When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of

pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the

mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication

Gene Wiki entry for HBXIP

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the HBXIP gene

Entrez Gene cytogenetic band: 1p13.3 Ensembl cytogenetic band: 1p13.3 HGNC cytogenetic band: 1p12

HBXIP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M110655: (about GC identifiers)

Start:	110,745,394 bp from pter
End:	110,752,083 bp from pter
Size:	6,690 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000001.9 NT_019273.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: HBXIP_HUMAN, O43504 (See protein sequence)

Recommended Name: Hepatitis B virus X-interacting protein

Size: 91 amino acids; 9614 Da

Subunit: Interacts with phosphorylated BIRC5; the resulting complex binds pro-caspase-9, as well as

active caspase-9, but much less efficiently. Interacts with SUPV3L1. Interacts with hepatitis B

virus (HBV) oncoprotein HBX C-terminus

Subcellular location: Cytoplasm

Miscellaneous: Suppression of caspase activation by the BIRC5/HBXIP complex is increased in the

presence of HBX

Secondary accessions: Q6IBD8

Post-translational modifications:

Phosphorylated upon DNA damage, probably by ATM or ATR¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_006393.2

ENSEMBL proteins:

ENSP00000256644 ENSP00000358790

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (HBXIP)
	Human Recombinant Proteins from Abnova (HBXIP)

OriGene Purified Recombinant Human Protein: HBXIP

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005829	cytosol	IDA	12773388

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Antibodies for HBXIP:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for HBXIP
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (HBXIP), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (HBXIP)
	Novus Biologicals Antibodies for HBXIP

Assays for HBXIP:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: O43504

UniProtKB/Swiss-Prot: HBXIP_HUMAN, O43504

Similarity: Belongs to the HBXIP family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HBXIP)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (HBXIP)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006402

Applied Biosystems Silencer® siRNAs for HBXIP

Sigma-Aldrich siRNA for HBXIP

Sigma-Aldrich shRNA for HBXIP

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for HBXIP
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_006402
Myc/DDK tagged cDNA clone in CMV expression vector: NM_006402
untagged cDNA clones in CMV expression vector (see all 2): NM_006402

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_006402

UniProtKB/Swiss-Prot: HBXIP_HUMAN, O43504

Function: When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of

pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the

mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	12773388

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for HBXIP

5/14 Interacting proteins for HBXIP (O43504² ENSP00000256644³) via UniProtKB, MINT, and/or STRING (see all 14 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GAPDH	P04406²	MINT-63149
GAPDHL6	P04406²	MINT-63149
GIT1	Q9Y2X7²	MINT-63157
GPRASP1	Q5JY77²	MINT-63151
KIAA1377	Q9P2H0²	MINT-63156

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006916	anti-apoptosis	IDA	12773388
GO:0009615	response to virus	TAS	9499022
GO:0019079	viral genome replication	TAS	9499022
GO:0043154	negative regulation of caspase activity	IDA	12773388

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for HBXIP
3 Novoseek chemical compound relationships for HBXIP gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
sulfosuccinimidyl acetate	93.69	5	9169015 (2), 8843702 (1)
calcium	35.07	39	7964733 (5), 15217911 (4), 11258952 (4), 8843702 (1) (see all 6)
lipid	0.00	1	16977318 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HBXIP)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (HBXIP)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006402

Sigma-Aldrich siRNA for HBXIP

Sigma-Aldrich shRNA for HBXIP

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_006402

REFSEQ mRNAs for HBXIP gene:

NM_006402.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_006402

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_006402
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_006402
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_006402

Additional cDNA sequence:

AF029890.1 AY623819.1 BC062619.1 CR456866.1 CR542130.1 CR602221.1

10 DOTS entries:

DT.219581 DT.100819655 DT.86853027 DT.121326297 DT.121326300 DT.121326308 DT.121326313 DT.455717

DT.92432900 DT.121419014

24/390 AceView cDNA sequences (see all 390 ):

AI188911 AA131708 CB529219 AA995522 CR542130 AA442400 BU951785 AA760790

AA860073 CB125188 AA336492 BQ636393 AA040361 BU734283 BQ271819 CB158516

BM673048 AI167843 AA488862 AA310122 AI185664 BM856576 AA723202 BU736893

highest scoring ESTs for HBXIP:

AF029890 AA029338 AA040360 AA131609 AA131613 AA186552 AA192745 AA299763 AA328469 AA359845

Unigene Cluster for HBXIP:

Hepatitis B virus x interacting protein

Hs.439815 [show with all ESTs]

Unigene Representative Sequence: BU957124

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for HBXIP

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3a	·	3b	^	4a	·	4b	^	5a	·	5b	·	5c
SP1:							-				-						-
SP2:							-		-		-						-
SP3:											-						-
SP4:							-		-		-
SP5:																	-

About this scheme

ECgene alternative splicing isoforms for HBXIP

2 Ensembl transcripts including schematic representations:

ENST00000256644 ENST00000369775

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

HBXIP expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for HBXIP

¹ / ² / ³

5 probe-sets matching HBXIP gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
38054_at²^{, 3}	U95-A	2	1.00	0.78	1.00	1.00	AF029890	1.00	1.00	1.00	1
202299_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_006402	0.60	1.00	0.82	1
202300_at²^{, 3}	U133-A	2	1.00	0.82	--	--	NM_006402	0.60	1.00	0.82	1
202299_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
202300_at²	U133Plus2	2	1.00	0.82	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TTTTGAAGCA

SOURCE GeneReport for Unigene cluster: Hs.439815
Expression variation in blood from EXPOLDB for HBXIP
UniProtKB/Swiss-Prot: HBXIP_HUMAN, O43504
Tissue specificity: Highly expressed in skeletal and cardiac muscle, followed by pancreas, kidney,
liver, brain, placenta and lung. Elevated levels in both cancerous and non-cancerous liver tissue
of patients with chronic HBV infection compared with hepatic tissue without HBV infection

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for HBXIP gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	HBXIP¹	--	hepatitis B virus x interacting protein	91.56(n) 100(a)	479907 XM_537033.2 XP_537033.2
chimpanzee (Pan troglodytes)	HBXIP¹	--	hepatitis B virus x interacting protein	99.23(n) 99.42(a)	457120 XM_513650.2 XP_513650.1
cow (Bos taurus)	HBXIP¹	--	hepatitis B virus x interacting protein	95.97(n) 100(a)	516090 NM_001034517.1 NP_001029689.1
rat (Rattus norvegicus)	Hbxip¹	--	hepatitis B virus x interacting protein	84.21(n) 81.2(a)	295357 XM_215674.4 XP_215674.4
mouse (Mus musculus)	Hbxip^{1, 5}	3⁵	hepatitis B virus x interacting protein^{1, 5}	84.4(n)¹ 80.14(a)¹	68576¹ XM_001480844.1¹ XP_001480894.1¹ AI552736⁵ AK003358⁵ (see all 8)

About this table Species with no ortholog for HBXIP

ENSEMBL Gene Tree for HBXIP

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/34 NCBI SNPs in HBXIP are shown (see all 34 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 31)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs6698159^1,2	A,C,F,H	110751800(+)	`CCAGCG/AGCACG`	1	L/P	mis¹ ese³		15	NA EU EA WA	1380
	rs6674775^1,2	A,C,F,H	110751962(+)	`GAAGGC/TTTGGG`	1	S/N	mis¹ ese³		15	NA EU EA WA	1394
	rs4839377^1,2	C,F,H	110753681(+)	`AACCAG/AAGTCC`	1	--	ng3¹		4	EU EA WA	416
	rs1161^1,2	C,F,H	110745610(-)	`TTAATT/CACCTT`	1	--	ut3¹		8	MN EU EA WA NA	734
--	rs2270686^1,2	H	110745645(-)	`CAGCAG/TCCTGT`	1	--	ut3¹ ese³		5	EA EU WA	1900
--	rs11541367^1,2	H	110748107(-)	`CCTCTG/TACCCC`	1	D/Y	mis¹ ese³		4	EU EA WA	406
	rs11102099^1,2	C,F,H	110751985(+)	`TGACCG/ATCGAG`	1	D/D	syn¹		15	EU EA WA NA	1398
	rs6684395^1,2	A,C,F,H	110751380(+)	`TCGACT/ACTGCA`	1	--	int¹		4	EU EA WA	408
	rs6671673^1,2	A,C,F,H	110751243(+)	`CTTTAT/CACTTT`	1	--	int¹		11	NA EU EA WA	914
	rs12135220^1,2	A,F,H	110747817(+)	`TATTTG/ATTACT`	1	--	int¹		4	EU EA WA	416

About this table

HapMap Linkage Disequilibrium images for HBXIP (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 608521

1 Novoseek disease relationship for HBXIP gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
hepatitis b	45.41	17	17303008 (2), 16982752 (2), 18158869 (1), 12773388 (1) (see all 6)

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/38 PubMed articles for HBXIP gene (see all 38 ):

Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication. (PubMed id 9499022)^{2, 3, 4} Melegari M.... Wands J.R. (1998)
HBXIP functions as a cofactor of survivin in apoptosis suppression. (PubMed id 12773388)^{1, 3, 4} Marusawa H....Reed J.C. (2003)
Human ATP-dependent RNA/DNA helicase hSuv3p interacts with the cofactor of survivin HBXIP. (PubMed id 16176273)^{3, 4} Minczuk M....Stepien P.P. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Involvement of hepatitis B X-interacting protein (HBXIP) in proliferation regulation of cells. (PubMed id 17303008)^{1, 3} Wang F.Z....Ye L.H. (2007)
Promotion of cell proliferation by HBXIP via upregulation of human telomerase reverse transcriptase in human mesenchymal stem cells. (PubMed id 18158869)^{1, 3} Wang F.Z....Zhang X.D. (2008)
Applying a highly specific and reproducible cDNA RDA method to clone garlic up-regulated genes in human gastric cancer cells. (PubMed id 11925594)^{1, 3} Li Y. and Lu Y.Y. (2002)
Interaction of hepatitis B viral oncoprotein with cellular target HBXIP dysregulates centrosome dynamics and mitotic spindle formation. (PubMed id 18032378)³ Wen Y....Reed J.C. (2008)
Hepatitis B virus X protein stimulates the mitochondrial translocation of Raf-1 via oxidative stress. (PubMed id 17428866)³ Chen J. and Siddiqui A. (2007)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PubMed id 17525332)⁴ Matsuoka S.... Elledge S.J. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 10542	HGNC: 17955	AceView: HBXIP	Ensembl:ENSG00000134248	euGenes: HUgn10542
ECgene: HBXIP	H-InvDB: HBXIP

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for HBXIP
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for HBXIP:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for HBXIP-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for HBXIP		Antibodies for HBXIP
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for HBXIP		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (HBXIP)
	Antibodies (HBXIP)
	Chimera RNAi (HBXIP)
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	Custom Service for Rabbit Pab from Full-length Protein

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	Antibodies (HBXIP)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for HBXIP

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for HBXIP

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HBXIP Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for HBXIP

Summaries
for HBXIP

Genomic Location
for HBXIP

Proteins
for HBXIP

Protein Domains/
Families
for HBXIP

Gene Function
for HBXIP

Pathways & Interactions
for HBXIP

Drugs & Compounds
for HBXIP

Transcripts
for HBXIP

Expression
for HBXIP

Orthologs
for HBXIP

Paralogs
for HBXIP

SNPs/Variants
for HBXIP

Disorders & Mutations
for HBXIP

Medical News
for HBXIP

Publications
for HBXIP

Search for HBXIP

Genome Databases showing HBXIP

Other Databases showing HBXIP

Specialized Databases showing HBXIP

Licensable Technologies
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Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

HBXIP Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor HBXIP

Summariesfor HBXIP

Genomic Locationfor HBXIP

Proteinsfor HBXIP

Protein Domains/Familiesfor HBXIP

Gene Functionfor HBXIP

Pathways & Interactionsfor HBXIP

Drugs & Compoundsfor HBXIP

Transcriptsfor HBXIP

Expression for HBXIP

Orthologsfor HBXIP

Paralogsfor HBXIP

SNPs/Variantsfor HBXIP

Disorders & Mutationsfor HBXIP

Medical Newsfor HBXIP

Publicationsfor HBXIP

Search for HBXIP

Genome Databases showing HBXIP

Other Databases showing HBXIP

Specialized Databases showing HBXIP

Licensable Technologiesfor HBXIP

Servicesfor HBXIP

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for HBXIP

Summaries
for HBXIP

Genomic Location
for HBXIP

Proteins
for HBXIP

Protein Domains/
Families
for HBXIP

Gene Function
for HBXIP

Pathways & Interactions
for HBXIP

Drugs & Compounds
for HBXIP

Transcripts
for HBXIP

Expression
for HBXIP

Orthologs
for HBXIP

Paralogs
for HBXIP

SNPs/Variants
for HBXIP

Disorders & Mutations
for HBXIP

Medical News
for HBXIP

Publications
for HBXIP

Licensable Technologies
for HBXIP

Services
for HBXIP