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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HBP1 Gene

protein-coding   GIFtS: 56
GCID: GC07P106809

HMG-Box Transcription Factor 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
HMG-Box Transcription Factor 11 2
High Mobility Group Box Transcription Factor 12 3
HMG Box Transcription Factor 12 3
HMG Box-Containing Protein 12
USMCC25

External Ids:    HGNC: 232001   Entrez Gene: 269592   Ensembl: ENSG000001058567   OMIM: 6118105   UniProtKB: O603813   

Export aliases for HBP1 gene to outside databases

Previous GC identifers: GC07P105293 GC07P106356 GC07P106369 GC07P106403 GC07P106596 GC07P101170


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for HBP1 Gene: 
HBP1 (HMG-box transcription factor 1) is a protein-coding gene. Diseases associated with HBP1 include retinoblastoma, and osteoarthritis. GO annotations related to this gene include RNA binding and DNA binding.

UniProtKB/Swiss-Prot: HBP1_HUMAN, O60381
Function: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the
regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'.
Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4

Gene Wiki entry for HBP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HBP1 gene promoter:
         AML1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 6): HBP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for HBP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HBP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22-q31   Ensembl cytogenetic band:  7q22.3   HGNC cytogenetic band: 7q22-q31

HBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HBP1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P106809:  view genomic region     (about GC identifiers)

Start:
106,809,406 bp from pter      End:
106,842,974 bp from pter
Size:
33,569 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 106,170,547-106,204,061     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HBP1_HUMAN, O60381 (See protein sequence)
Recommended Name: HMG box-containing protein 1  
Size: 514 amino acids; 57645 Da
Subunit: Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1
Subcellular location: Nucleus
Sequence caution: Sequence=BAB85059.1; Type=Erroneous initiation;
2 PDB 3D structures from and Proteopedia for HBP1:
2E6O (3D)        3QVE (3D)    
Secondary accessions: B3KVB7 Q8TBM1 Q8TE93 Q96AJ2
Alternative splicing: 3 isoforms:  O60381-1   O60381-2   O60381-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for HBP1: NX_O60381

Explore proteomics data for HBP1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O60381

  • HBP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HBP1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001231191.1  NP_036389.2  

    ENSEMBL proteins: 
     ENSP00000420500   ENSP00000418022   ENSP00000420137   ENSP00000222574   ENSP00000420281  
     ENSP00000417631   ENSP00000418738   ENSP00000417927   ENSP00000418017   ENSP00000475809  
     ENSP00000419143  

    Human Recombinant Protein Products for HBP1: 
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    Novus Biologicals HBP1 Protein
    Novus Biologicals HBP1 Lysate
    Sino Biological Recombinant Protein for HBP1
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HBP1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    HBP1 for ontologies           About GeneDecksing



    HBP1 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR013723 Ataxin-1_HBP1
     IPR003652 Ataxin_AXH_dom
     IPR009071 HMG_box_dom

    Graphical View of Domain Structure for InterPro Entry O60381

    ProtoNet protein and cluster: O60381

    UniProtKB/Swiss-Prot: HBP1_HUMAN, O60381
    Similarity: Contains 1 AXH domain
    Similarity: Contains 1 HMG box DNA-binding domain


    HBP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HBP1_HUMAN, O60381
    Function: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the
    regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'.
    Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4

         Genatlas biochemistry entry for HBP1:
    histone hairpin binding protein 1,31kDa,involved in replication-dependent histone gene expression

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003723RNA binding IEA--
    GO:0005515protein binding IPI--
         
    HBP1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for HBP1:
     Increased cell death in breast 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Hbp1):
     behavior/neurological  hematopoietic system  homeostasis/metabolism  immune system  no phenotypic analysis 

    HBP1 for phenotypes           About GeneDecksing

    Animal Models:
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HBP1 
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    SwitchGear 3'UTR luciferase reporter plasmidHBP1 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for HBP1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Signaling mediated by p38-alpha and p38-beta
    Signaling mediated by p38-alpha and p38-beta
    2E2F transcription factor network
    E2F transcription factor network
    3C-MYC pathway
    C-MYC pathway
    4Regulation of Wnt-mediated beta catenin signaling and target gene transcription
    Regulation of Wnt-mediated beta catenin signaling and target gene transcription


    4 BioSystems Pathways for HBP1
        Signaling mediated by p38-alpha and p38-beta
    E2F transcription factor network
    C-MYC pathway
    Regulation of Wnt-mediated beta catenin signaling and target gene transcription



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HBP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/38 Interacting proteins for HBP1 (O603812, 3 ENSP000002225744) via UniProtKB, MINT, STRING, and/or I2D (see all 38)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADRM1Q161862, 3, ENSP000002530034MINT-2869185 I2D: score=1 STRING: ENSP00000253003
    EFEMP2O959672, 3, ENSP000003099534MINT-2872699 I2D: score=1 STRING: ENSP00000309953
    GKAP1Q5VSY02, 3, ENSP000003655504MINT-2876688 I2D: score=1 STRING: ENSP00000365550
    SERPINI2O758302, 3, ENSP000002646774MINT-2861759 I2D: score=1 STRING: ENSP00000264677
    ZG16O608442, 3, ENSP000003835634MINT-2878488 I2D: score=1 STRING: ENSP00000383563
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0007050cell cycle arrest NAS9030690
    GO:0016055Wnt receptor signaling pathway IEA--
    GO:0043268positive regulation of potassium ion transport IEA--

    HBP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HBP1

    Search CenterWatch for drugs/clinical trials and news about HBP1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HBP1 gene (2 alternative transcripts): 
    NM_001244262.1  NM_012257.3  

    Unigene Cluster for HBP1:

    HMG-box transcription factor 1
    Hs.162032  [show with all ESTs]
    Unigene Representative Sequence: NM_012257
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000468410(uc011klv.2) ENST00000478930 ENST00000464009 ENST00000222574(uc003vdy.3 uc003vdz.3)
    ENST00000468401 ENST00000468116 ENST00000497535 ENST00000485846 ENST00000479011
    ENST00000463202(uc003veb.1) ENST00000498408(uc003vea.3) ENST00000461963
    ENST00000483809 ENST00000607681 ENST00000463790
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidHBP1 3' UTR sequence
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    Additional mRNA sequence: 

    AF019214.1 AF182038.1 AK025284.1 AK074353.1 AK122785.1 AK295910.1 AK298504.1 BC017069.1 
    BC022329.2 

    24 DOTS entries:

    DT.95112747  DT.427564  DT.102836928  DT.95309090  DT.100877367  DT.121103104  DT.92465934  DT.92465940 
    DT.121102998  DT.92465944  DT.121102986  DT.121103107  DT.121103149  DT.100877357  DT.121102966  DT.121103102 
    DT.121103160  DT.70104055  DT.97805124  DT.100877361  DT.100877362  DT.100877364  DT.438484  DT.95304157 

    24/322 AceView cDNA sequences (see all 322):

    AI610724 BU162581 BU194447 AA766707 BF940134 N79083 H24763 BG696521 
    AL548310 R46438 AK074353 BQ002066 AU139761 BM472614 AI675962 AA411932 
    AI274188 BX492885 AI802677 AA761533 AA729310 BE139582 CR594009 BP342004 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for HBP1 (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11a · 11b · 11c ^
    SP1:                                      -                                                                                                     -               
    SP2:                    -     -     -     -     -     -                                                                                         -               
    SP3:                                                                                                                                            -               
    SP4:                                                                                                                                            -               
    SP5:              -     -     -     -     -     -     -                                                                                                         

    ExUns: 12a · 12b · 12c ^ 13a · 13b ^ 14a · 14b
    SP1:              -           -               
    SP2:              -           -               
    SP3:              -                           
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for HBP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HBP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGTTGCCCC
    HBP1 Expression
    About this image


    See HBP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HBP1

    SOURCE GeneReport for Unigene cluster: Hs.162032
        SABiosciences Custom PCR Arrays for HBP1
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for HBP1 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hbp11 , 5 high mobility group box transcription factor 11, 5 92.28(n)1
    95.14(a)1
      12 (13.73 cM)5
    733891  NM_153198.21  NP_694878.21 
     319262545 
    chicken
    (Gallus gallus)
    Aves HBP11 HMG-box transcription factor 1 82(n)
    84.74(a)
      417705  NM_001199454.1  NP_001186383.1 
    lizard
    (Anolis carolinensis)
    Reptilia HBP16
    Uncharacterized protein
    82(a)
    1 ↔ 1
    5(97271211-97286042)
    African clawed frog
    (Xenopus laevis)
    Amphibia hbp1-A2 HMG-box containing protein 1 81.36(n)    AF530514.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hbp11 HMG-box transcription factor 1 65.76(n)
    68.13(a)
      554137  NM_001024431.1  NP_001019602.1 


    ENSEMBL Gene Tree for HBP1 (if available)
    TreeFam Gene Tree for HBP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HBP1 gene
    18/19 SIMAP similar genes for HBP1 using alignment to 8 protein entries:     HBP1_HUMAN (see all proteins) (see all similar genes):
    SUMO1    KIAA0101    LSM12    SEPSECS    NAE1    VPS33A
    COQ5    FLJ00047    NXPE2    SIPA1L3    TUBA1C    ARIH1
    TNNT1    TBCB    DPP9    EIF3G    CIC    IRF5

    HBP1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/498 SNPs in HBP1 are shown (see all 498)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs350626271,2
    C--106807411(+) AGCTC-/TTTTTT 1 -- us2k10--------
    rs2573851,2
    C,F--106807448(+) TTAGTT/CTTCTA 1 -- us2k11Minor allele frequency- C:0.21NA 120
    rs680645691,2
    C--106807653(+) TGAGTC/AACTAA 2 -- us2k13Minor allele frequency- A:0.06WA NA 240
    rs2573861,2
    C,F--106807783(+) GTGAAC/GATAGA 2 -- us2k15Minor allele frequency- G:0.16NA 250
    rs1416977781,2
    --106807785(+) GAACAC/TAGAAA 2 -- us2k10--------
    rs1129879471,2
    C,F--106807935(+) GTATAT/CTTAAA 2 -- us2k12Minor allele frequency- C:0.06CSA WA 120
    rs9576671,2
    C,H--106807968(-) TATTTC/TTTTAA 2 -- us2k1 tfbs37Minor allele frequency- T:0.00NA EA NS 666
    rs1505423531,2
    --106808029(+) CTTACA/TAATGT 2 -- us2k10--------
    rs1388749651,2
    --106808136(+) GGGGGA/GAAAAG 2 -- us2k10--------
    rs612636381,2
    C--106816202(+) TCGCC-/CAGGCT 2 -- int10--------

    HapMap Linkage Disequilibrium report for HBP1 (106809406 - 106842974 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for HBP1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv831087CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611810    OMIM disorders: --

    5 diseases for HBP1:    About MalaCards
    retinoblastoma    osteoarthritis    pancreatic cancer    pancreatitis
    breast cancer

    1 disease from the University of Copenhagen DISEASES database for HBP1:
    Ureter cancer

    HBP1 for disorders           About GeneDecksing

    2 Novoseek inferred disease relationships for HBP1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoblastoma 36.3 2 9030690 (1), 10030670 (1)
    tumors 5.38 8 19223422 (2), 15225871 (2), 20383199 (2), 16179914 (1)


    Export disorders for HBP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HBP1 gene, integrated from 9 sources (see all 44):
    (articles sorted by number of sources associating them with HBP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1. (PubMed id 11500377)1, 2, 3, 9 Sampson E.M....Yee A.S. (2001)
    2. HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family. (PubMed id 9030690)1, 3, 9 Tevosian S.G....Yee A.S. (1997)
    3. Human HMG box transcription factor HBP1: a role in hCD2 LCR function. (PubMed id 10562551)1, 2, 9 Zhuma T....Kioussis D. (1999)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    7. Involvement of retinoblastoma protein and HBP1 in histone H1(0) gene expression. (PubMed id 10958660)1, 2 Lemercier C.... Khochbin S. (2000)
    8. Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer. (PubMed id 17616670)1, 9 Paulson K.E....Yee A.S. (2007)
    9. Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells. (PubMed id 16179914)1, 9 Yao C.J.... Austin G.E. (2005)
    10. HBP1 repression of the p47phox gene: cell cycle regulation via the NADPH oxidase. (PubMed id 15024088)1, 9 Berasi S.P....Paulson K.E. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26959 HGNC: 23200 AceView: HBP1 Ensembl:ENSG00000105856 euGenes: HUgn26959
    ECgene: HBP1 H-InvDB: HBP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HBP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for HBP1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HBP1 gene:
    Search GeneIP for patents involving HBP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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