Aliases for HBP1 Gene
External Ids for HBP1 Gene
Previous GeneCards Identifiers for HBP1 Gene
GeneCards Summary for HBP1 Gene
HBP1 (HMG-Box Transcription Factor 1) is a Protein Coding gene. Diseases associated with HBP1 include ureter cancer. Among its related pathways are Regulation of Wnt-mediated beta catenin signaling and target gene transcription and E2F transcription factor network. GO annotations related to this gene include RNA binding.
UniProtKB/Swiss-Prot for HBP1 Gene
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5-TTCATTCATTCA-3. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.