Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneAnalytics
- GeneLoc
- GenesLikeMe
- VarElect
- PathCards
Terms of Use
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
GeneCards Plus
- Premium Tools
  
  Learn more

Set Analyses:

VarElect

Advanced Search

HBM Gene

protein-coding GIFtS: 42
GCID: GC16P000203

Hemoglobin, Mu

(Previous names: hemoglobin, alpha pseudogene 2)
(Previous symbol: HBAP2)

Try our

MalaCards

disease database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

TryGeneCards Plus

Aliases
Hemoglobin, Mu¹ ²		Alpha Globin Pseudogene 2²
HBAP2¹ ² ³		Hemoglobin Subunit Mu²
Hemoglobin, Alpha Pseudogene 2¹ ²		mu-globin²
Hemoglobin Mu Chain² ³		Mu-globin³

External Ids:	HGNC: 4826¹	Entrez Gene: 3042²	Ensembl: ENSG00000206177⁷	OMIM: 609639⁵	UniProtKB: Q6B0K9³

Export aliases for HBM gene to outside databases

Previous GC identifers: GC16U900495 GC16P000161 GC16P000163 GC16P000164 GC16P000165 GC16P000174 GC16P000175 GC16P000177 GC16P000179 GC16P000134

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for HBM Gene:

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta -

pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. This gene has an ORF encoding a 141 aa

polypeptide which is similar to the delta globins found in reptiles and birds. This locus was originally

described as a pseudogene; however, it is currently thought to be a protein-coding gene. (provided by RefSeq, Jul

2008)

GeneCards Summary for HBM Gene:

HBM (hemoglobin, mu) is a protein-coding gene. GO annotations related to this gene include iron ion binding and oxygen binding. An important paralog of this gene is HBE1.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus

RefSeq DNA sequence at NCBI GenBank:

NC_000016.9 NC_018927.2 NT_010393.17

Regulatory elements:

Regulatory transcription factor binding sites in the HBM gene promoter:
COUP-TF1 Sp1 AP-1 ATF-2 c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HBM promoter sequence

Search Chromatin IP Primers for HBM

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HBM

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3

HBM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HBM gene location

GeneLoc information about chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16P000203: view genomic region (about GC identifiers)

Start:	203,891 bp from pter	End:	216,767 bp from pter
Size:	12,877 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: HBM_HUMAN, Q6B0K9 (See protein sequence)

Recommended Name: Hemoglobin subunit mu

Size: 141 amino acids; 15618 Da

Developmental stage: Maximal expression during the erythroblast terminal differentiation

Explore the universe of human proteins at neXtProt for HBM: NX_Q6B0K9

Explore proteomics data for HBM at MOPED

See HBM Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_001003938.1

ENSEMBL proteins:

ENSP00000349270

HBM Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein for HBM OriGene Protein Over-expression Lysate for HBM OriGene MassSpec for HBM OriGene Custom Protein Services for HBM
	GenScript Custom Purified and Recombinant Proteins Services for HBM
	Novus Biologicals HBM Lysate
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Cloud-Clone Corp.
	Search eBioscience for Proteins for HBM
	antibodies-online proteins for HBM (2 products)
	Search antibodies-online for peptides for HBM

HBM Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for HBM
	Search for Antibodies for HBM at Abcam
	Browse Antibodies at Cloud-Clone Corp.
	ThermoFisher Antibodies for HBM
	antibodies-online antibodies for HBM (3 products)

HBM Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for HBM
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for HBM
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.
	Search eBioscience for ELISAs for HBM
	antibodies-online kits for HBM (19 products)

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus

4 InterPro protein domains:

IPR012292 Globin_dom

IPR002338 Haemoglobin_a

IPR009050 Globin-like

IPR000971 Globin

Graphical View of Domain Structure for InterPro Entry Q6B0K9

ProtoNet protein and cluster: Q6B0K9

UniProtKB/Swiss-Prot: HBM_HUMAN, Q6B0K9

Similarity: Belongs to the globin family

Find genes that share domains with HBM About GenesLikeMe

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Gene Ontology (GO): 4 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005344	oxygen transporter activity	IEA	--
GO:0005506	iron ion binding	IEA	--
GO:0019825	oxygen binding	IEA	--
GO:0020037	heme binding	IEA	--

Find genes that share ontologies with HBM About GenesLikeMe

Animal Models:

genOway: Develop your customized and physiologically relevant rodent model for HBM

miRNA Products:		Block miRNA regulation of human, mouse, rat HBM using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate HBM
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for HBM
		Predesigned siRNA for gene silencing in human, mouse, rat HBM

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for HBM

Clone Products:		OriGene clones in human, mouse for HBM (see all 6) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: HBM (NM_001003938)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for HBM
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HBM

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for HBM
		Browse ESI BIO Cell Lines and PureStem Progenitors for HBM

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HBM

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
cytosol	2
nucleus	2
extracellular	1

About this image

Gene Ontology (GO): 1 cellular component term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005833	hemoglobin complex	IEA	--

Find genes that share ontologies with HBM About GenesLikeMe

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for HBM
Interactions:

Search GeneGlobe Interaction Network for HBM

STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

Selected Interacting proteins for HBM (ENSP00000349270⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 15)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
COLGALT2	ENSP00000354960⁴	STRING: ENSP00000354960
COMMD3	ENSP00000366032⁴	STRING: ENSP00000366032
VPS72	ENSP00000357887⁴	STRING: ENSP00000357887
HBE1	ENSP00000292896⁴	STRING: ENSP00000292896
HBG1	ENSP00000327431⁴	STRING: ENSP00000327431

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for HBM

1 HMDB Compound for HBM About this table

Compound	Synonyms	CAS #	PubMed Ids
Heme	(protoporphyrinato)iron (see all 19)	14875-96-8	--

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for HBM gene:

NM_001003938.3

Unigene Cluster for HBM:

Hemoglobin, mu

Hs.647389 [show with all ESTs]

Unigene Representative Sequence: BM920011

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000472539 ENST00000496585 ENST00000356815(uc002cfu.1)

miRNA Products:		Block miRNA regulation of human, mouse, rat HBM using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate HBM
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for HBM
		Predesigned siRNA for gene silencing in human, mouse, rat HBM

Clone Products:		OriGene clones in human, mouse for HBM (see all 6) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: HBM (NM_001003938)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for HBM
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HBM

Primer Products:		OriGene qPCR primer pairs and template standards for HBM OriGene qSTAR qPCR primer pairs in human, mouse for HBM
		Pre-validated RT² qPCR Primer Assay in human, mouse / rat HBM
		QuantiTect SYBR Green Assays in human, mouse, rat HBM
		QuantiFast Probe-based Assays in human, mouse, rat HBM

Additional mRNA sequence:

AY698022.2 BC035682.1 BC067870.1

3 DOTS entries:

DT.435305 DT.92418458 DT.97797418

Selected AceView cDNA sequences (see all 2898):

CR595536 AW161306 AA300328 BQ477883 AA359389 R22107 CR618898 N23732

CR601289 AA340470 H00404 AJ706144 BU070898 CR610186 BX424381 H47987

R71733 CR612274 AA321332 AA359582 AA295036 AA333751 BU947789 CR606457

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

HBM expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: CTGGCGGCTG

About this image

HBM expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 2) fully expand


Adipose (Muscoskeletal System)
Mesenchymal Stem Cells Subcutaneous White Adipose

Mesenchymal Stem Cells
Mesenchymal Stem Cells Subcutaneous White Adipose

HBM Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

HBM Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.647389

UniProtKB/Swiss-Prot: HBM_HUMAN, Q6B0K9

Tissue specificity: Expressed in erythroid tissues

Custom PCR Arrays for HBM

Primer Products:		OriGene qPCR primer pairs and template standards for HBM OriGene qSTAR qPCR primer pairs in human, mouse for HBM
		Pre-validated RT² qPCR Primer Assay in human, mouse / rat HBM
		QuantiTect SYBR Green Assays in human, mouse, rat HBM
		QuantiFast Probe-based Assays in human, mouse, rat HBM

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HBM

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of chordates.

Orthologs for HBM gene from Selected species (see all 6) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
dog (Canis familiaris)	Mammalia	HBM¹	hemoglobin, mu	89.36(n) 87.94(a)		100855616 XM_003639129.2 XP_003639177.1
chicken (Gallus gallus)	Aves	HBAD⁶	Gallus gallus alpha-D-globin (HBAD), mRNA.	50(a)	1 ↔ 1	AADN03010595.1(8017-9433)
lizard (Anolis carolinensis)	Reptilia	HBM⁶	hemoglobin, mu	46(a)	1 ↔ 1	AAWZ02037681(2920-4064)
zebrafish (Danio rerio)	Actinopterygii	HBQ1⁶	hemoglobin, theta 1	40(a)	1 → many	12(21688563-21689767) ENSDARG00000045144

ENSEMBL Gene Tree for HBM (if available)
TreeFam Gene Tree for HBM (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

TryGeneCards Plus

Paralogs for HBM gene

HBE1² HBG2² HBZ² HBG1² HBD² HBA2² HBB² HBQ1²

HBA1²

9 SIMAP similar genes for HBM using alignment to 1 protein entry: HBM_HUMAN:

HBZ HBA2 HBA1 HBE1 HBG1 HBG2

HBQ1 HBB HBD

Find genes that share paralogs with HBM About GenesLikeMe

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

SNP ID	Valid	Clinical significance	Chr 16 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs181146037^1,2		--	214770(+)	`CGGGGC/TGGGGT`	1	--	us2k¹		0	--	--	--	--
rs185588149^1,2		--	214964(+)	`CGGGGC/TGGGGT`	1	--	us2k¹		0	--	--	--	--
rs191824200^1,2		--	215096(+)	`CCCACG/TCCGCC`	1	--	us2k¹		0	--	--	--	--
rs183595817^1,2		--	215097(+)	`CCACGC/TCGCCT`	1	--	us2k¹		0	--	--	--	--
rs7194649^1,2	C,F,A	--	215106(+)	`CTGGGC/ACAAGT`	1	--	us2k¹		4		WA NA	242
rs187006147^1,2	C	--	215144(+)	`CCGAGA/TAGTAC`	1	--	us2k¹		0	--	--	--	--
rs114579464^1,2	C,F	--	215219(+)	`CACAGT/GTCCTG`	1	--	us2k¹		1		WA	118
rs113635258^1,2	C,F	--	215340(+)	`TCGGTA/CGTCCC`	1	--	us2k¹		1		CSA	1
rs147659542^1,2		--	215344(+)	`TCGTCC/TCCACT`	1	--	us2k¹		0	--	--	--	--
rs2541677^1,2	C,F,A,H	--	215379(-)	`AGGCGC/TCCCCC`	1	--	us2k¹		18		NS EA WA CSA NA	2328

HapMap Linkage Disequilibrium report for HBM (203891 - 216767 bp)

Structural Variations
Database of Genomic Variants (DGV) Selected variations for HBM (see all 14): About this table

Variant ID	Type	Subtype	PubMed ID
esv2662940	CNV	Deletion	23128226
esv2422427	CNV	Duplication	17116639
dgv2462n71	CNV	Loss	21882294
dgv2461n71	CNV	Loss	21882294
dgv2459n71	CNV	Loss	21882294
dgv2458n71	CNV	Loss	21882294
dgv2460n71	CNV	Loss	21882294
nsv518291	CNV	Loss	19592680
nsv904652	CNV	Loss	21882294
dgv2455n71	CNV	Loss	21882294

Human Gene Mutation Database (HGMD): HBM

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing HBM

DNA2.0 Custom Variant and Variant Library Synthesis for HBM

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus

OMIM gene information: 609639 OMIM disorders: --

Find genes that share disorders with HBM About GenesLikeMe

Export disorders for HBM gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for HBM gene integrated from 10 sources:
(articles sorted by number of sources associating them with HBM)

Utopia: connect your pdf to the dynamic
world of online information

A newly discovered human alpha-globin gene. (PubMed id 15855277)^{1, 2, 3} Goh S.-H.... Miller J.L. (Blood 2005)
A review of the molecular genetics of the human alpha-globin gene cluster. (PubMed id 2649166)^{1, 3} Higgs D.R....Weatherall D.J. (Blood 1989)
Unusual features of CpG-rich (HTF) islands in the human alpha globin complex: association with non-functional pseudogenes and presence within the 3' portion of the zeta gene. (PubMed id 2825132)^{1, 3} Fischel-Ghodsian N....Higgs D.R. (Nucleic Acids Res. 1987)
Persistent cyanosis in a 4 month old infant with severe pneumonia and haemoglobin M. (PubMed id 19199228)¹ HA1tten M....Heimann K. (Klin Padiatr 2009)
A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter. (PubMed id 16728641)² De Gobbi M.... Higgs D.R. (Science 2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S.... Malek J. (Genome Res. 2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
A previously undetected pseudogene in the human alpha globin gene cluster. (PubMed id 3952001)¹ Hardison R.C....Schmid C.W. (Nucleic Acids Res. 1986)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus

Entrez Gene: 3042	HGNC: 4826	AceView: HB_	Ensembl:ENSG00000206177	euGenes: HUgn3042
ECgene: HBM	H-InvDB: HBM

(According to HUGE)
About This Section

TryGeneCards Plus

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus

Name	Description
PharmGKB entry for HBM	Pharmacogenomics, SNPs, Pathways

Intellectual Property for HBM gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

TryGeneCards Plus

Patent Information for HBM gene:
Search GeneIP for patents involving HBM

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
About This Section

TryGeneCards Plus


	EMD Millipore genomic analysis products

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Enzyme Activity Assays/Reagents
	Browse ELISpot/FluoroSpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Luminex Assays
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Recombinant/Natural Proteins		Browse Stem Cell Products
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for HBM
	OriGene qPCR primer pairs and template standards for HBM		OriGene Protein Over-expression Lysate for HBM
	OriGene MassSpec for HBM		OriGene clones in human, mouse for HBM
	OriGene qSTAR qPCR primer pairs in human, mouse for HBM		OriGene Purified Protein for HBM
	Browse OriGene ORF clones		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for HBM		OriGene Custom Protein Services for HBM

	Block miRNA regulation of human, mouse, rat HBM using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing HBM
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HBM		Predesigned siRNA for gene silencing in human, mouse, rat HBM
	QuantiFast Probe-based Assays in human, mouse, rat HBM		QuantiTect SYBR Green Assays in human, mouse, rat HBM
	Custom PCR Arrays for HBM		Search Chromatin IP Primers for HBM
	Pre-validated RT² qPCR Primer Assay in human, mouse / rat HBM		Search GeneGlobe Interaction Network for HBM
	Regulatory tfbs in HBM promoter

	GenScript Custom Purified and Recombinant Proteins Services for HBM		GenScript cDNA clones with any tag delivered in your preferred vector for HBM
	GenScript Custom Assay Services for HBM		GenScript Custom overexpressing Cell Line Services for HBM
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

Search for Antibodies & Assays

Search Tocris compounds for HBM

	Browse Sino Biological Proteins
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	HBM lysates

	Search for Antibodies for HBM at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for HBM
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Browse Proteins at Cloud-Clone Corp.
	Browse Antibodies at Cloud-Clone Corp.
	Browse ELISAs at Cloud-Clone Corp.
	Browse CLIAs at Cloud-Clone Corp.

Browse ESI BIO Cell Lines and PureStem Progenitors for HBM

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HBM

	Browse SwitchGear 3'UTR luciferase reporter plasmids for HBM
	SwitchGear Promoter luciferase reporter plasmids for HBM

ThermoFisher Antibodies for HBM

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HBM

Browse compounds at ApexBio

Search Addgene for plasmids for HBM

	Search eBioscience for proteins for HBM
	Search eBioscience for elisas for HBM
	eBioscience FlowRNA Probe Sets

genOway: Develop your customized and physiologically relevant rodent model for HBM

	antibodies-online antibodies for HBM (3 products)
	antibodies-online kits for HBM (19 products)
	Search antibodies-online for peptides for HBM
	antibodies-online proteins for HBM (2 products)

GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 2 Nov 2014 , 8 Jan 2015

View Random Gene

Category			(GIFtS: )
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes HBM gene at Home site.

Version: 3.12.300 21 Jan 2015
hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4

GeneCards Plus

Advanced Search

Export list of displayed genes

HBM Gene

Hemoglobin, Mu

Aliases
for HBM gene

Summaries
for HBM gene

Genomic Views
for HBM gene

Proteins
for HBM gene

HBM Human Recombinant Protein Products:

HBM Antibody Products:

HBM Assay Products:

Domains /
Families
for HBM gene

Function
for HBM gene

Localization
for HBM gene

Pathways & Interactions
for HBM gene

Drugs & Compounds
for HBM gene

Transcripts
for HBM gene

Expression
for HBM gene

Orthologs
for HBM gene

Paralogs
for HBM gene

Genomic Variants
for HBM gene

Disorders / Diseases
for HBM gene

Publications
for HBM gene

External Searches for HBM gene

Genome Databases showing HBM gene

Other Databases showing HBM gene

Specialized Databases showing HBM gene

Intellectual Property
for HBM gene

Products
for HBM gene

View Random Gene

GeneCards Plus

Advanced Search

Export list of displayed genes

HBM Gene

Hemoglobin, Mu

Aliasesfor HBM gene

Summariesfor HBM gene

Genomic Viewsfor HBM gene

Proteinsfor HBM gene

HBM Human Recombinant Protein Products:

HBM Antibody Products:

HBM Assay Products:

Domains /Familiesfor HBM gene

Functionfor HBM gene

Localizationfor HBM gene

Pathways & Interactionsfor HBM gene

Drugs & Compoundsfor HBM gene

Transcriptsfor HBM gene

Expression for HBM gene

Orthologsfor HBM gene

Paralogsfor HBM gene

Genomic Variantsfor HBM gene

Disorders / Diseasesfor HBM gene

Publicationsfor HBM gene

External Searches for HBM gene

Genome Databases showing HBM gene

Other Databases showing HBM gene

Specialized Databases showing HBM gene

Intellectual Propertyfor HBM gene

Productsfor HBM gene

View Random Gene

Aliases
for HBM gene

Summaries
for HBM gene

Genomic Views
for HBM gene

Proteins
for HBM gene

Domains /
Families
for HBM gene

Function
for HBM gene

Localization
for HBM gene

Pathways & Interactions
for HBM gene

Drugs & Compounds
for HBM gene

Transcripts
for HBM gene

Expression
for HBM gene

Orthologs
for HBM gene

Paralogs
for HBM gene

Genomic Variants
for HBM gene

Disorders / Diseases
for HBM gene

Publications
for HBM gene

Intellectual Property
for HBM gene

Products
for HBM gene