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HBE1 Gene

protein-coding GIFtS: 54

GC11M005247

hemoglobin, epsilon 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
Epsilon-globin ^³
HBE ^¹, ², ³
OTTHUMP00000069642 ^²

Descriptions
Hemoglobin epsilon chain ^³
epsilon globin ^²
hemoglobin, epsilon 1 ^²

External Ids
HGNC: 4830¹
Entrez Gene: 3046²
UniProtKB: P02100³
Ensembl: ENSG00000213931⁷

Search outside databases for aliases for HBE1 gene

Previous GC identifers: GC11M006037 GC11M005591 GC11M005249 GC11M005214 GC11M005233

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for HBE1:

The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains

together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower

I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these

embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five

beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order:

5'-epsilon - G-gamma - A-gamma - delta - beta-3' [provided by RefSeq]

UniProtKB/Swiss-Prot: HBE_HUMAN, P02100

Function: The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin

Gene Wiki entry for HBE1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the HBE1 gene

Entrez Gene cytogenetic band: 11p15.5 Ensembl cytogenetic band: 11p15.4 HGNC cytogenetic band: 11p15.5

HBE1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M005247: (about GC identifiers)

Start:	5,246,156 bp from pter
End:	5,483,423 bp from pter
Size:	237,268 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000011.8 NT_009237.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: HBE_HUMAN, P02100 (See protein sequence)

Recommended Name: Hemoglobin subunit epsilon

Size: 147 amino acids; 16203 Da

Subunit: Heterotetramer of two alpha chains and two epsilon chains in early embryonic hemoglobin

Gower-2; two zeta chains and two epsilon chains in early embryonic hemoglobin Gower-1

PDB structures from and Proteopedia :

1A9W (3D)

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_005321.1

ENSEMBL proteins:

ENSP00000292896 ENSP00000380104 ENSP00000369586

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich Proteins for HBE1
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse Abcam for Recombinant Proteins
	Human Recombinant Proteins from Abnova (HBE1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005833	hemoglobin complex	TAS	7555018

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Antibodies for HBE1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for HBE1

Assays for HBE1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P02100

ProtoNet protein and cluster: P02100

1 Blocks protein family: IPB002337 Beta haemoglobin signature

UniProtKB/Swiss-Prot: HBE_HUMAN, P02100

Similarity: Belongs to the globin family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HBE1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (HBE1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005330

Applied Biosystems Silencer® siRNAs for HBE1

Sigma-Aldrich siRNA for HBE1

Sigma-Aldrich shRNA for HBE1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for HBE1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_005330
Myc/DDK tagged cDNA clone in CMV expression vector: NM_005330
untagged cDNA clone in CMV expression vector: NM_005330

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_005330

UniProtKB/Swiss-Prot: HBE_HUMAN, P02100

Function: The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin

Genatlas biochemistry entry for HBE1:

hemoglobin,epsilon 1,embryonic

2 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Hbb-y):

no phenotypic analysis

normal

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005344	oxygen transporter activity	TAS	7555018
GO:0019825	oxygen binding	IEA	--
GO:0020037	heme binding	IEA	--
GO:0046872	metal ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for HBE1

2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006810	transport	IEA	--
GO:0015671	oxygen transport	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for HBE1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HBE1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (HBE1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005330

Sigma-Aldrich siRNA for HBE1

Sigma-Aldrich shRNA for HBE1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_005330

REFSEQ mRNAs for HBE1 gene:

NM_005330.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_005330

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_005330
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_005330
                                 untagged cDNA clone in CMV expression vector: NM_005330

Additional cDNA sequence:

BC015537.2 CR541912.1

7 DOTS entries:

DT.120723442 DT.95262173 DT.95262172 DT.120723319 DT.100806001 DT.309847 DT.95323075

4 AceView cDNA sequences:

NM_005330 CR541912 BC015537 BC022184

highest scoring ESTs for HBE1:

BP432922 BP428807 AA089473 AA092238 BE789678 BF211542 BG220871 BG496579 BP429018 BP430146

Unigene Cluster for HBE1:

Hemoglobin, epsilon 1

Hs.655195 [show with all ESTs]

Unigene Representative Sequence: BC015537

GeneLoc Exon Structure

3 Ensembl transcripts including schematic representations:

ENST00000292896 ENST00000396895 ENST00000380237

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

HBE1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for HBE1

¹ / ² / ³

3 probe-sets matching HBE1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
41617_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AI349593	0.20	0.50	0.38	1
205919_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_005330	0.40	0.67	0.55	1
205919_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GGGACTGGGC

SOURCE GeneReport for Unigene cluster: Hs.655195
Expression variation in blood from EXPOLDB for HBE1
UniProtKB/Swiss-Prot: HBE_HUMAN, P02100
Tissue specificity: Red blood cells

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for HBE1 gene from 5/7 species (see all 7 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	HBE1¹	--	hemoglobin, epsilon 1	87.3(n) 87.76(a)	485256 XM_542374.2 XP_542374.2
cow (Bos taurus)	HBE1¹	--	hemoglobin, epsilon 1	88.89(n) 89.8(a)	539994 XM_590745.3 XP_590745.1
rat (Rattus norvegicus)	Hbe1¹	--	hemoglobin, epsilon 1	83.67(n) 82.31(a)	293267 NM_001008890.1 NP_001008890.1
mouse (Mus musculus)	Hbb-y^{1, 5}	7 (49.95 cM)⁵	hemoglobin Y, beta-like embryonic chain^{1, 5}	83.9(n)¹ 80.95(a)¹	15135¹ NM_008221.3¹ NP_032247.1¹ AK011619⁵ AK012501⁵ (see all 19)
chicken (Gallus gallus)	HBG2¹	--	hemoglobin, gamma G	75.96(n) 74.83(a)	396485 NM_205489.1 NP_990820.1

About this table Species with no ortholog for HBE1

ENSEMBL Gene Tree for HBE1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for HBE1 gene

HBB² HBG2² CYGB² HBG1² HBD²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/44 NCBI SNPs in HBE1 are shown (see all 44 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 22)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs7479652^1,2	A,C,F,H	5249689(+)	`TCTTTT/CAGCTA`	1	--	ng3¹		3		EU EA	300
	rs3759071^1,2	A,C,F,H	5248108(-)	`AAATGT/CGCTTT`	1	--	ng3¹		4		EU EA WA	418
	rs3759070^1,2	A,C,F,H	5248204(-)	`AGAGAG/CCTAGA`	1	--	ng3¹		5		EA EU WA	1860
	rs3759067^1,2	A,C,F	5248768(-)	`AGCATA/GAGCAA`	1	--	ng3¹		2		NA	182
	rs11822578^1,2	A,C,F	5245882(+)	`TAACAC/GCTCCT`	1	--	ng5¹		2		NA	182
	rs3759069^1,2	A,C	5248406(-)	`GATTCC/TCTGGA`	1	--	ng3¹		0	--	--	--	--
	rs2213165^1,2	F,H	5246253(-)	`CAGGTG/CTTCCT`	1	--	ut3¹		7		EA NA EU WA	478
--	rs10768737^1,2	A	5248448(+)	`GGACAC/TTGGCT`	1	--	ng3¹		0	--	--	--	--
--	rs34195803^1,2	--	5245779(+)	`ATTCT-/CAGCCT`	1	--	ng5¹		0	--	--	--	--
--	rs36009050^1,2	--	5249042(+)	`CTTTC-/TTTTTTT`	1	--	ng3¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for HBE1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 142100

1 Novoseek disease relationship for HBE1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
erythroleukemia	58.99	2	1431310 (2)

About this table

Human Gene Mutation Database: HBE1
Genetic Association Database: HBE1
Human Genome Epidemiology Navigator: HBE1 (4 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/133 PubMed articles for HBE1 gene (see all 133 ):

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Should we screen for globin gene mutations in blood samples with mean corpuscular volume (MCV) greater than 80 fL in areas with a high prevalence of thalassaemia? (PubMed id 11304851)^{3, 6} Chan L.C....Chui D.H. (2001)
Few reports of hemoglobin E/beta-thalassemia in Northeast India: underdiagnosis or complete exclusion of beta-thalassemia by hemoglobin E. (PubMed id 11132230)^{3, 6} Krishnamurti L. (2000)
Crystal structure of a human embryonic haemoglobin: the carbonmonoxy form of Gower II (alpha2 epsilon2) haemoglobin at 2.9-A resolution. (PubMed id 9665850)^{3, 4} Sutherland-Smith A.J....Baker E.N. (1998)
A review of the molecular genetics of the human alpha-globin gene cluster. (PubMed id 2649166)^{2, 3} Higgs D.R....Weatherall D.J. (1989)
Embryonic hemoglobin: sequence of the epsilon and zeta chains. (PubMed id 6172865)^{3, 4} Clegg J.B. (1981)
The primary structure of the human epsilon-globin gene. (PubMed id 6254663)^{3, 4} Baralle F.E.... Proudfoot N.J. (1980)
Genomic and phylogenetic footprinting at the epsilon-globin silencer region in intact human cells. (PubMed id 15157738)^{1, 3} Temple M.D....Murray V. (2004)
Linear distance from the locus control region determines epsilon-globin transcriptional activity. (PubMed id 17548470)^{1, 3} Shimotsuma M....Tanimoto K. (2007)
Embryonic hemoglobins are expressed in definitive cells. (PubMed id 10381533)^{1, 3} Luo H.Y....Alter B.P. (1999)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 3046	HGNC: 4830	AceView: HBE1	Ensembl:ENSG00000213931	euGenes: HUgn3046
ECgene: HBE1	H-InvDB: HBE1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for HBE1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for HBE1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for HBE1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for HBE1		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Proteins for HBE1
	Lentivirus-delivered shRNAs for HBE1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Search Novus for antibodies for HBE1

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HBE1 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for HBE1

Summaries
for HBE1

Genomic Location
for HBE1

Proteins
for HBE1

Protein Domains/
Families
for HBE1

Gene Function
for HBE1

Pathways & Interactions
for HBE1

Drugs & Compounds
for HBE1

Transcripts
for HBE1

Expression
for HBE1

Orthologs
for HBE1

Paralogs
for HBE1

SNPs/Variants
for HBE1

Disorders & Mutations
for HBE1

Medical News
for HBE1

Publications
for HBE1

Search for HBE1

Genome Databases showing HBE1

Other Databases showing HBE1

Specialized Databases showing HBE1

Licensable Technologies
for HBE1

Services
for HBE1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

HBE1 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor HBE1

Summariesfor HBE1

Genomic Locationfor HBE1

Proteinsfor HBE1

Protein Domains/Familiesfor HBE1

Gene Functionfor HBE1

Pathways & Interactionsfor HBE1

Drugs & Compoundsfor HBE1

Transcriptsfor HBE1

Expression for HBE1

Orthologsfor HBE1

Paralogsfor HBE1

SNPs/Variantsfor HBE1

Disorders & Mutationsfor HBE1

Medical Newsfor HBE1

Publicationsfor HBE1

Search for HBE1

Genome Databases showing HBE1

Other Databases showing HBE1

Specialized Databases showing HBE1

Licensable Technologiesfor HBE1

Servicesfor HBE1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for HBE1

Summaries
for HBE1

Genomic Location
for HBE1

Proteins
for HBE1

Protein Domains/
Families
for HBE1

Gene Function
for HBE1

Pathways & Interactions
for HBE1

Drugs & Compounds
for HBE1

Transcripts
for HBE1

Expression
for HBE1

Orthologs
for HBE1

Paralogs
for HBE1

SNPs/Variants
for HBE1

Disorders & Mutations
for HBE1

Medical News
for HBE1

Publications
for HBE1

Licensable Technologies
for HBE1

Services
for HBE1