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HBE1 Gene

protein-coding   GIFtS: 55
GCID: GC11M005289

Hemoglobin, Epsilon 1

  See HBE1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Hemoglobin, Epsilon 11 2     epsilon-globin2
Hemoglobin Epsilon Chain2 3     Hemoglobin Subunit Epsilon2
HBE2 3     Epsilon-globin3
Epsilon Globin2     

External Ids:    HGNC: 48301   Entrez Gene: 30462   Ensembl: ENSG000002139317   OMIM: 1421005   UniProtKB: P021003   

Export aliases for HBE1 gene to outside databases

Previous GC identifers: GC11M006037 GC11M005591 GC11M005249 GC11M005214 GC11M005233 GC11M005247 GC11M004949


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HBE1 Gene:
The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with
two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains
together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally
supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb
cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3' (provided by
RefSeq, Jul 2008)

GeneCards Summary for HBE1 Gene:
HBE1 (hemoglobin, epsilon 1) is a protein-coding gene. Diseases associated with HBE1 include ascariasis, and hepatitis d. GO annotations related to this gene include iron ion binding and oxygen binding. An important paralog of this gene is HBG2.

UniProtKB/Swiss-Prot: HBE_HUMAN, P02100
Function: The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin

Gene Wiki entry for HBE1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_009237.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the HBE1 gene promoter:
         TBP   FOXF2   MEF-2   Lmo2   MEF-2A   NF-AT2   TFIID   aMEF-2   NF-AT1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for HBE1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HBE1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.5

HBE1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HBE1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M005289:  view genomic region     (about GC identifiers)

Start:
5,289,580 bp from pter      End:
5,526,847 bp from pter
Size:
237,268 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HBE_HUMAN, P02100 (See protein sequence)
Recommended Name: Hemoglobin subunit epsilon  
Size: 147 amino acids; 16203 Da
Subunit: Heterotetramer of two alpha chains and two epsilon chains in early embryonic hemoglobin Gower-2; two zeta
chains and two epsilon chains in early embryonic hemoglobin Gower-1
1 PDB 3D structure from and Proteopedia for HBE1:
1A9W (3D)    
Secondary accessions: Q6FH44

Explore the universe of human proteins at neXtProt for HBE1: NX_P02100

Explore proteomics data for HBE1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HBE1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005321.1  
    ENSEMBL proteins: 
     ENSP00000369586   ENSP00000380104   ENSP00000292896  
    Reactome Protein details: P02100

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    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for HBE1 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR012292 Globin_dom
     IPR009050 Globin-like
     IPR000971 Globin
     IPR002337 Haemoglobin_b

    Graphical View of Domain Structure for InterPro Entry P02100

    ProtoNet protein and cluster: P02100

    1 Blocks protein domain: IPB002337 Beta haemoglobin signature

    UniProtKB/Swiss-Prot: HBE_HUMAN, P02100
    Similarity: Belongs to the globin family


    Find genes that share domains with HBE1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HBE_HUMAN, P02100
    Function: The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin

         Genatlas biochemistry entry for HBE1:
    hemoglobin,epsilon 1,embryonic

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005344oxygen transporter activity IEA--
    GO:0005506iron ion binding IEA--
    GO:0019825oxygen binding IEA--
    GO:0020037heme binding IEA--
    GO:0031721hemoglobin alpha binding IEA--
         
    Find genes that share ontologies with HBE1           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Hbb-y):
     no phenotypic analysis  normal 

    Find genes that share phenotypes with HBE1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for HBE1: Hbb-yHbb-tm2.2Fier Hbb-yHbb-tm1Fier Hbb-yHbb-tm2.1Fier

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HBE1
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    hsa-mir-335-5p (MIRT017542)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    nucleus3
    extracellular2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005833hemoglobin complex IEA--
    GO:0072562blood microparticle IDA--

    Find genes that share ontologies with HBE1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for HBE1 About    
    See pathways by source

    SuperPathContained pathways About
    1Hemostasis
    Hemostasis0.43
    2Factors involved in megakaryocyte development and platelet production
    Factors involved in megakaryocyte development and platelet production


    Find genes that share SuperPaths with HBE1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for HBE1
        Factors involved in megakaryocyte development and platelet production


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HBE1
    Interactions:

        GeneGlobe Interaction Network for HBE1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 20)

    Selected Interacting proteins for HBE1 (P021003 ENSP000002928964) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HBA1P699053, ENSP000003224214I2D: score=2 STRING: ENSP00000322421
    HBA2P699053, ENSP000002515954I2D: score=2 STRING: ENSP00000251595
    MAFGENSP000003503694STRING: ENSP00000350369
    MAFKENSP000003449034STRING: ENSP00000344903
    NFE2ENSP000003124364STRING: ENSP00000312436
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    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0007596blood coagulation TAS--
    GO:0051291protein heterooligomerization IEA--

    Find genes that share ontologies with HBE1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HBE1 (HBE)

    1 HMDB Compound for HBE1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Heme(protoporphyrinato)iron (see all 19)14875-96-8--

    1 Novoseek inferred chemical compound relationship for HBE1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    chloramphenicol 12.7 1 2236025 (1)



    Find genes that share compounds with HBE1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HBE1 gene: 
    NM_005330.3  

    Unigene Cluster for HBE1:

    Hemoglobin, epsilon 1
    Hs.655195  [show with all ESTs]
    Unigene Representative Sequence: BC015537
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000380237(uc001mal.1 uc001mam.1) ENST00000396895 ENST00000292896

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    Additional mRNA sequence: 

    BC015537.2 CR541912.1 

    19 DOTS entries:

    DT.95186195  DT.120723442  DT.95262173  DT.95262172  DT.91866943  DT.95180915  DT.100806001  DT.120723250 
    DT.95371917  DT.100774732  DT.75131589  DT.95345553  DT.120723406  DT.120723319  DT.309847  DT.95233683 
    DT.95323075  DT.92413533  DT.95092533 

    4 AceView cDNA sequences:

    CR541912 NM_005330 BC022184 BC015537 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HBE1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGACTGGGC
    HBE1 Expression
    About this image


    HBE1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 17) fully expand
     
     Heart (Cardiovascular System)    fully expand to see all 3 entries
             Cardiac Crescent Cells Cardiac Crescent
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Metanephros
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Mesenchymal Condensate Cells Zeugopod
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             Mesenchymal Condensate Cells Zeugopod
     
     Limb (Muscoskeletal System)    fully expand to see all 2 entries
             Mesenchymal Condensate Cells Zeugopod
    HBE1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HBE1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655195

    UniProtKB/Swiss-Prot: HBE_HUMAN, P02100
    Tissue specificity: Red blood cells

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HBE1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hbb-y5
    Hbb-bh11
    hemoglobin Y, beta-like embryonic chain5
    hemoglobin Z, beta-like embryonic chain1
    79.82(n)1
    77.55(a)1
      7 (54.85 cM)5
    151321  NM_008219.31  NP_032245.11 
     1038517455 
    chicken
    (Gallus gallus)
    Aves HBG21 hemoglobin, gamma G 75.96(n)
    74.83(a)
      396485  NM_205489.1  NP_990820.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    64(a)
    1 → many
    GL344018.1(38428-41710)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia CF781582.12   -- 71.96(n)    CF781582.1 
    zebrafish
    (Danio rerio)
    Actinopterygii NM_131021.12   -- 75.52(n)   30217  NM_131021.1 


    ENSEMBL Gene Tree for HBE1 (if available)
    TreeFam Gene Tree for HBE1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HBE1 gene
    HBG22  HBZ2  HBG12  HBD2  HBA22  HBB2  HBQ12  HBA12  
    HBM2  
    12 SIMAP similar genes for HBE1 using alignment to 3 protein entries:     HBE_HUMAN (see all proteins):
    HBG2    HBB    HBD    HBG1    G-gamma    HBZ
    HBM    HBA2    HBA1    CYGB    HBQ1    MB

    Find genes that share paralogs with HBE1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HBE1 (see all 145)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1112330941,2
    F--4948420(-) AAAAA-/CAAAAA
            
    CAAAA
    2 -- ds5001 cds11Minor allele frequency- CAAAAA:0.09NS 320
    rs30617501,2
    C--4949067(-) tgttt-/GTTT  
            
    tttCA
    1 -- int11Minor allele frequency- GTTT:0.50CSA 2
    rs341363341,2
    C--4949068(+) GAAAA-/AAAC  
            
    AACAA
    1 -- int10--------
    rs2019853591,2
    C--4949087(-) GCCGTG/TTTTGT 1 -- int10--------
    rs38344661,2
    C--4950734(-) GTCAC-/ACTGTC 1 -- us2k10--------
    rs721286091,2
    C--4951637(+) CTTTC-/TTTTTTT 1 -- us2k10--------
    rs728725481,2
    C,F--5203392(+) AATTTC/AATAAA 1 -- ds50016Minor allele frequency- A:0.27NA CSA NS WA EA 708
    rs2000462021,2
    C--5203400(+) AAAAC-/ATGTGAC 1 -- ds50010--------
    rs118225781,2
    C,F,A,H--5203564(+) TAACAC/GCTCCT 1 -- ds500115Minor allele frequency- G:0.13NA WA CSA NS EA 893
    rs1475508451,2
    --5203638(+) CCCCGA/GTAAAG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for HBE1 (5289580 - 5526847 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for HBE1: --
    Human Gene Mutation Database (HGMD): HBE1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HBE1
    DNA2.0 Custom Variant and Variant Library Synthesis for HBE1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 142100    OMIM disorders: --

    7 diseases for HBE1:    
    About MalaCards
    ascariasis    hepatitis d    trichuriasis    hepatitis e
    cerebral malaria    hereditary persistence of fetal hemoglobin    malaria

    9 diseases from the University of Copenhagen DISEASES database for HBE1:
    Hepatitis B     Hepatitis     Thalassemia     Liver cirrhosis
    Anemia     Hepatitis A     Hepatitis D     Hepatocellular carcinoma
    Hepatitis E

    Find genes that share disorders with HBE1           About GenesLikeMe

    1 Novoseek inferred disease relationship for HBE1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    erythroleukemia 58.2 2 1431310 (2)

    Genetic Association Database (GAD): HBE1
    Human Genome Epidemiology (HuGE) Navigator: HBE1 (5 documents)

    Export disorders for HBE1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HBE1 gene, integrated from 10 sources (see all 157):
    (articles sorted by number of sources associating them with HBE1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1, 4 He C....Hunter D.J. (Hum. Genet. 2010)
    2. Lack of association of the HbE variant with protection from cerebral malaria in Thailand. (PubMed id 18787944)1, 4 Naka I....Patarapotikul J. (Biochem. Genet. 2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Should we screen for globin gene mutations in blood samples with mean corpuscular volume (MCV) greater than 80 fL in areas with a high prevalence of thalassaemia? (PubMed id 11304851)1, 4 Chan L.C....Chui D.H. (J. Clin. Pathol. 2001)
    5. Few reports of hemoglobin E/beta-thalassemia in Northeast India: underdiagnosis or complete exclusion of beta-thalassemia by hemoglobin E. (PubMed id 11132230)1, 4 Krishnamurti L. (J. Pediatr. Hematol. Oncol. 2000)
    6. Crystal structure of a human embryonic haemoglobin: the carbonmonoxy form of Gower II (alpha2 epsilon2) haemoglobin at 2.9-A resolution. (PubMed id 9665850)1, 2 Sutherland-Smith A.J....Baker E.N. (J. Mol. Biol. 1998)
    7. A review of the molecular genetics of the human alpha-globin gene cluster. (PubMed id 2649166)1, 3 Higgs D.R....Weatherall D.J. (Blood 1989)
    8. The primary structure of the human epsilon-globin gene. (PubMed id 6254663)1, 2 Baralle F.E.... Proudfoot N.J. (Cell 1980)
    9. Embryonic hemoglobin: sequence of the epsilon and zeta chains. (PubMed id 6172865)1, 2 Clegg J.B. (Tex. Rep. Biol. Med. 1980)
    10. Genomic and phylogenetic footprinting at the epsilon-globin silencer region in intact human cells. (PubMed id 15157738)1, 9 Temple M.D....Murray V. (Biochim. Biophys. Acta 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3046 HGNC: 4830 AceView: HBE1 Ensembl:ENSG00000213931 euGenes: HUgn3046
    ECgene: HBE1 H-InvDB: HBE1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HBE1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HBE1 gene:
    Search GeneIP for patents involving HBE1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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