Aliases for HAVCR1 Gene
External Ids for HAVCR1 Gene
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]
GeneCards Summary for HAVCR1 Gene
HAVCR1 (Hepatitis A Virus Cellular Receptor 1) is a Protein Coding gene. Diseases associated with HAVCR1 include multicentric reticulohistiocytosis and cutaneous fibrous histiocytoma. GO annotations related to this gene include virus receptor activity. An important paralog of this gene is HAVCR2.
UniProtKB/Swiss-Prot for HAVCR1 Gene
May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair.