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HAUS6 Gene

protein-coding   GIFtS: 53
GCID: GC09M019047

HAUS Augmin-Like Complex, Subunit 6

(Previous names: family with sequence similarity 29, member A)
(Previous symbol: FAM29A)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
HAUS Augmin-Like Complex, Subunit 61 2     Dgt62
FAM29A1 2 3 5     Dim Gamma-Tubulin Homolog2
Family With Sequence Similarity 29, Member A1 2     HAUS Augmin-Like Complex Subunit 62
DGT63 5     KIAA15743

External Ids:    HGNC: 259481   Entrez Gene: 548012   Ensembl: ENSG000001478747   OMIM: 6134335   UniProtKB: Q7Z4H73   

Export aliases for HAUS6 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HAUS6 Gene:
The protein encoded by this gene is a subunit of the augmin complex. The augmin complex plays a role in
microtubule attachment to the kinetochore and central spindle formation. This protein may have a role in
efficient chromosome congression and segregation by promoting microtubule-dependent microtubule amplification.
Pseudogenes of this gene are located on chromosomes 7 and 20. Alternative splicing results in multiple transcript
variants that encode different protein isoforms. (provided by RefSeq, Aug 2012)

GeneCards Summary for HAUS6 Gene:
HAUS6 (HAUS augmin-like complex, subunit 6) is a protein-coding gene. Diseases associated with HAUS6 include pulmonary tuberculosis, and tuberculosis.

UniProtKB/Swiss-Prot: HAUS6_HUMAN, Q7Z4H7
Function: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of
cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle
through recruitment of NEDD1 and gamma-tubulin

Gene Wiki entry for HAUS6 (FAM29A) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NC_018920.2  NT_008413.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the HAUS6 gene promoter:
         C/EBPbeta   AML1a   HNF-1A   SRY   FAC1   FOXC1   ARP-1   Pax-4a   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHAUS6 promoter sequence
   Search Chromatin IP Primers for HAUS6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HAUS6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p22.1   Ensembl cytogenetic band:  9p22.1   HGNC cytogenetic band: 9p22.1

HAUS6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HAUS6 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M019047:  view genomic region     (about GC identifiers)

Start:
19,053,141 bp from pter      End:
19,103,117 bp from pter
Size:
49,977 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HAUS6_HUMAN, Q7Z4H7 (See protein sequence)
Recommended Name: HAUS augmin-like complex subunit 6  
Size: 955 amino acids; 108621 Da
Subunit: Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and
this interaction is required for spindle assembly. Interacts with PLK1 and NEDD1
Sequence caution: Sequence=AAH26178.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence; Sequence=AAI11042.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAA90922.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB14334.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB14388.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=BAG63294.1; Type=Erroneous initiation;
Note=Translation N-terminally extended;
Secondary accessions: B3KPK4 B4DX82 Q05CG1 Q14CB6 Q14CD9 Q2TA91 Q6IQ10 Q6NZX5 Q8IZQ4 Q96FN0
Q9H950 Q9H998 Q9HCJ8 Q9NXT8
Alternative splicing: 3 isoforms:  Q7Z4H7-1   Q7Z4H7-2   Q7Z4H7-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for HAUS6: NX_Q7Z4H7

Explore proteomics data for HAUS6 at MOPED

Post-translational modifications: 

  • Phosphorylated during mitosis1
  • Ubiquitination2 at Lys199, Lys598, Lys694, Lys704, Lys847
  • Modification sites at PhosphoSitePlus

  • See HAUS6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001257819.1  NP_060115.3  

    ENSEMBL proteins: 
     ENSP00000369871   ENSP00000369865   ENSP00000409615  

    HAUS6 Human Recombinant Protein Products:

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    Novus Biologicals HAUS6 Protein
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    HAUS6 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for HAUS6
    Cloud-Clone Corp. CLIAs for HAUS6


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HAUS: HAUS augmin-like complex subunits

    2 InterPro protein domains:
     IPR026797 HAUS_6
     IPR028163 HAUS_6_N

    Graphical View of Domain Structure for InterPro Entry Q7Z4H7

    ProtoNet protein and cluster: Q7Z4H7

    UniProtKB/Swiss-Prot: HAUS6_HUMAN, Q7Z4H7
    Similarity: Belongs to the HAUS6 family


    HAUS6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HAUS6_HUMAN, Q7Z4H7
    Function: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of
    cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle
    through recruitment of NEDD1 and gamma-tubulin

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    HAUS6 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for HAUS6:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HAUS6
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HAUS6

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HAUS6
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HAUS6

    miRNA
    Products:
        
    miRTarBase miRNAs that target HAUS6:
    hsa-mir-320a (MIRT044486), hsa-mir-196a-5p (MIRT048214), hsa-let-7b-5p (MIRT052232), hsa-mir-124-3p (MIRT022559)

    Block miRNA regulation of human, mouse, rat HAUS6 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HAUS6 (see all 30):
    hsa-miR-302d hsa-miR-520e hsa-miR-4328 hsa-miR-302e hsa-miR-519a hsa-miR-3916 hsa-miR-3125 hsa-miR-3167
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Predesigned siRNA for gene silencing in human, mouse, rat HAUS6

    Gene Editing
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HAUS6 (NM_017645)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HAUS6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAUS6

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAUS6


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HAUS6_HUMAN, Q7Z4H7: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton,
    microtubule organizing center, centrosome. Note=Localizes to interphase centrosomes and to mitotic spindle
    microtubules
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus4
    cytosol3
    extracellular1
    golgi apparatus1
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome IDA--
    GO:0005819spindle IEA--
    GO:0005874microtubule IEA--

    HAUS6 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HAUS6
    Interactions:

        Search GeneGlobe Interaction Network for HAUS6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for HAUS6 (Q7Z4H72, 3 ENSP000003698714) via UniProtKB, MINT, STRING, and/or I2D (see all 39)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PARP2Q9UGN52, 3, ENSP000002504164MINT-8201867 I2D: score=1 STRING: ENSP00000250416
    HAUS2Q9NVX03, ENSP000002603724I2D: score=1 STRING: ENSP00000260372
    HAUS1Q96CS23, ENSP000002820584I2D: score=1 STRING: ENSP00000282058
    HAUS3Q68CZ63, ENSP000002437064I2D: score=1 STRING: ENSP00000243706
    HAUS4Q9H6D73, ENSP000002064744I2D: score=1 STRING: ENSP00000206474
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis IEA--
    GO:0051225spindle assembly IMP19369198
    GO:0051297centrosome organization IMP19427217

    HAUS6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HAUS6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HAUS6 gene (2 alternative transcripts): 
    NM_001270890.1  NM_017645.4  

    Unigene Cluster for HAUS6:

    HAUS augmin-like complex, subunit 6
    Hs.533468  [show with all ESTs]
    Unigene Representative Sequence: NM_017645
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000380502(uc011lmz.2 uc003znl.1 uc022bdv.1 uc003znk.3)
    ENST00000380496(uc003znm.1) ENST00000415524
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HAUS6 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HAUS6 (see all 30):
    hsa-miR-302d hsa-miR-520e hsa-miR-4328 hsa-miR-302e hsa-miR-519a hsa-miR-3916 hsa-miR-3125 hsa-miR-3167
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
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    Predesigned siRNA for gene silencing in human, mouse, rat HAUS6
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    GenScript: all cDNA clones in your preferred vector: HAUS6 (NM_017645)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAUS6
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for HAUS6
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HAUS6
      QuantiTect SYBR Green Assays in human, mouse, rat HAUS6
      QuantiFast Probe-based Assays in human, mouse, rat HAUS6

    Additional mRNA sequence: 

    AB046794.1 AF533709.1 AF537091.1 AK000067.1 AK022964.1 AK023068.1 AK056458.1 AK225209.1 
    AK301852.1 AL832495.1 BC010632.1 BC026178.1 BC065935.1 BC071625.1 BC111041.1 BC113981.1 
    BC114492.1 

    9 DOTS entries:

    DT.309225  DT.100777674  DT.102828029  DT.99973924  DT.100722075  DT.100736214  DT.121051178  DT.100777675 
    DT.101974607 

    Selected AceView cDNA sequences (see all 141):

    AA287858 BQ921432 CF264976 BQ422992 AA830203 AF537091 BC065935 CB852613 
    AI917312 AI590947 BQ961552 AK023068 AI379102 AI743579 AB046794 BM821351 
    BI463635 BM790193 AU133040 BU183722 NM_017645 AK056458 CA944516 AA284001 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HAUS6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGATGATTAA
    HAUS6 Expression
    About this image


    HAUS6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Kidney (Urinary System)
             Metanephros
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
     
     Eye (Sensory Organs)
             nGnG Amacrine Cells Inner Nuclear Layer
    HAUS6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HAUS6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.533468
        Custom PCR Arrays for HAUS6
    Primer
    Products:
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAUS6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HAUS6 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Haus61 , 5 HAUS augmin-like complex, subunit 61, 5 78.39(n)1
    65.8(a)1
      4 (40.69 cM)5
    2303761  NM_173400.21  NP_775576.21 
     865788555 
    chicken
    (Gallus gallus)
    Aves HAUS61 HAUS augmin-like complex, subunit 6 54.06(n)
    36.84(a)
      427238  NM_001031421.1  NP_001026592.1 
    lizard
    (Anolis carolinensis)
    Reptilia HAUS66
    HAUS augmin-like complex, subunit 6
    43(a)
    1 ↔ 1
    2(64605388-64623839)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.93932 Xenopus laevis transcribed sequences 80.2(n)    BJ096031.1 
    zebrafish
    (Danio rerio)
    Actinopterygii haus61 HAUS augmin-like complex, subunit 6 46.84(n)
    32.98(a)
      558814  NM_001079974.1  NP_001073443.1 


    ENSEMBL Gene Tree for HAUS6 (if available)
    TreeFam Gene Tree for HAUS6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HAUS6 gene

    HAUS6 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for HAUS6
    PGOHUM00000259635 PGOHUM00000233230 PGOHUM00000233234


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HAUS6 (see all 1470)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1154749771,2
    F--19052669(+) AGAGCG/AAAGAG 2 -- ds50011Minor allele frequency- A:0.01WA 118
    rs1902575601,2
    --19052794(+) GTTCAC/TTAAAC 2 -- ds50010--------
    rs22915031,2
    C,F,O,A,H--19052923(-) AGTTTT/ACACAT 2 -- ds5001113Minor allele frequency- A:0.46EA NS NA PA EU CA WA CSA 8328
    rs1828368991,2
    --19052930(+) AACTGA/TCAGTA 2 -- ds50010--------
    rs726964471,2
    C,F--19052986(+) ATCTAG/CTAATT 2 -- ds50011Minor allele frequency- C:0.05NA 120
    rs70458441,2
    C,F,A,H--19053114(+) TTTGAG/TATTAT 2 -- ds500125Minor allele frequency- T:0.42NS EA NA WA CSA 2532
    rs134404141,2
    C,H--19053141(+) CCAGAT/GAGTAT 2 -- ut314Minor allele frequency- G:0.00NS EA 390
    rs1882133501,2
    --19053242(+) CTATTA/CACAAT 2 -- ut310--------
    rs70313921,2
    C,F,A,H--19053247(+) CACAAT/CGCATA 2 -- ut31 ese319Minor allele frequency- C:0.10NA NS EA 2362
    rs1512547871,2
    C--19053279(+) GCAACC/TATGTA 2 -- ut310--------

    HapMap Linkage Disequilibrium report for HAUS6 (19053141 - 19103117 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for HAUS6:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv892700CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HAUS6
    DNA2.0 Custom Variant and Variant Library Synthesis for HAUS6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613433    OMIM disorders: --

    2 diseases for HAUS6:    
    About MalaCards
    pulmonary tuberculosis    tuberculosis


    HAUS6 for disorders           About GeneDecksing

    Genetic Association Database (GAD): HAUS6
    Human Genome Epidemiology (HuGE) Navigator: HAUS6 (1 document)

    Export disorders for HAUS6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HAUS6 gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with HAUS6)
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    1. HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity. (PubMed id 19427217)1, 2, 3 Lawo S....Pelletier L. (Curr. Biol. 2009)
    2. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. (PubMed id 19369198)1, 2 Uehara R....Goshima G. (Proc. Natl. Acad. Sci. U.S.A. 2009)
    5. FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle. (PubMed id 19029337)1, 2 Zhu H.... Fang G. (J. Cell Biol. 2008)
    6. Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle. (PubMed id 18443220)1, 2 Goshima G.... Vale R.D. (J. Cell Biol. 2008)
    7. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54801 HGNC: 25948 AceView: FAM29A Ensembl:ENSG00000147874 euGenes: HUgn54801
    ECgene: HAUS6 H-InvDB: HAUS6

    (According to HUGE)
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    HUGE: KIAA1574

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HAUS6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HAUS6 gene:
    Search GeneIP for patents involving HAUS6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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