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HAUS5 Gene

protein-coding   GIFtS: 44
GCID: GC19P036103

HAUS Augmin-Like Complex, Subunit 5

(Previous name: KIAA0841)
(Previous symbol: KIAA0841)
  Search for HAUS5
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
HAUS Augmin-Like Complex, Subunit 51 2
KIAA08411 2 3 5
dgt52
HAUS Augmin-Like Complex Subunit 52
DGT55

External Ids:    HGNC: 291301   Entrez Gene: 233542   Ensembl: ENSG000002491157   OMIM: 6134325   UniProtKB: O949273   

Export aliases for HAUS5 gene to outside databases

Previous GC identifers: GC19P040797 GC19P032608


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HAUS5 Gene:
HAUS5 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first
identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin
complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is
vital to mitotic spindle assembly (Goshima et al., 2008 (PubMed 18443220); Uehara et al., 2009 (PubMed
19369198)).(supplied by OMIM, Jun 2010)

GeneCards Summary for HAUS5 Gene:
HAUS5 (HAUS augmin-like complex, subunit 5) is a protein-coding gene.

UniProtKB/Swiss-Prot: HAUS5_HUMAN, O94927
Function: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of
cytokinesis as part of the HAUS augmin-like complex




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HAUS5 gene promoter:
         E2F-4   E2F-3a   AML1a   E2F-2   PPAR-gamma1   E2F   E2F-1   ZID   PPAR-gamma2   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for HAUS5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HAUS5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.12   Ensembl cytogenetic band:  19q13.12   HGNC cytogenetic band: 19q13.12

HAUS5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HAUS5 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P036103:  view genomic region     (about GC identifiers)

Start:
36,103,646 bp from pter      End:
36,116,251 bp from pter
Size:
12,606 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HAUS5_HUMAN, O94927 (See protein sequence)
Recommended Name: HAUS augmin-like complex subunit 5  
Size: 633 amino acids; 71682 Da
Subunit: Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and
this interaction is required for spindle assembly
Sequence caution: Sequence=AAH13947.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAA74864.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B2RXK1 Q6P2P7 Q7L3D5 Q96CT8
Alternative splicing: 2 isoforms:  O94927-1   O94927-2   

Explore the universe of human proteins at neXtProt for HAUS5: NX_O94927

Explore proteomics data for HAUS5 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys77, Lys208, Lys405, Lys428, Lys471, Lys540, Lys630
  • Modification sites at PhosphoSitePlus

  • See HAUS5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056117.1  
    ENSEMBL proteins: 
     ENSP00000466661   ENSP00000475856   ENSP00000439056   ENSP00000475934   ENSP00000467688  
     ENSP00000444373  

    HAUS5 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for HAUS5
    OriGene Custom MassSpec
    OriGene Custom Protein Services for HAUS5
    GenScript Custom Purified and Recombinant Proteins Services for HAUS5
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HAUS5

    HAUS5 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
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    Abcam antibodies for HAUS5
    Cloud-Clone Corp. Antibodies for HAUS5
    ThermoFisher Antibodies for HAUS5
    LSBio Antibodies in human, mouse, rat for HAUS5

    HAUS5 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for HAUS5
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for HAUS5
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for HAUS5
    Cloud-Clone Corp. CLIAs for HAUS5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HAUS: HAUS augmin-like complex subunits

    1 InterPro protein domain:
     IPR026215 HAUS5

    Graphical View of Domain Structure for InterPro Entry O94927

    ProtoNet protein and cluster: O94927

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: HAUS5_HUMAN, O94927
    Similarity: Belongs to the HAUS5 family


    HAUS5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HAUS5_HUMAN, O94927
    Function: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of
    cytokinesis as part of the HAUS augmin-like complex

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    HAUS5 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for HAUS5:
     Increased G2M DNA content  Increased number of mitotic ce 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HAUS5
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HAUS5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HAUS5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HAUS5

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat HAUS5 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate HAUS5:
    hsa-miR-185 hsa-miR-4306 hsa-miR-708* hsa-miR-4276 hsa-miR-488 hsa-miR-3907 hsa-miR-628-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for HAUS5
    Predesigned siRNA for gene silencing in human, mouse, rat HAUS5

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for HAUS5

    Clone
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    OriGene ORF clones in mouse, rat for HAUS5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HAUS5 (NM_015302)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HAUS5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAUS5

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for HAUS5 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAUS5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HAUS5_HUMAN, O94927: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton,
    spindle. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol2
    nucleus2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome IDA--
    GO:0005819spindle IEA--
    GO:0005874microtubule IEA--
    GO:0070652HAUS complex IDA19369198

    HAUS5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HAUS5
    Interactions:

        Search GeneGlobe Interaction Network for HAUS5

    Selected Interacting proteins for HAUS5 (O949272, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RGS2P412202, 3MINT-8268812 I2D: score=2 
    YAE1D1Q9NRH12, 3MINT-8250187 I2D: score=2 
    BECN1Q144573I2D: score=1 
    HAUS1Q96CS23I2D: score=1 
    HAUS2Q9NVX03I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis IEA--
    GO:0051225spindle assembly IMP19369198
    GO:0051297centrosome organization IMP19427217

    HAUS5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HAUS5



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HAUS5 gene: 
    NM_015302.1  

    Unigene Cluster for HAUS5:

    HAUS augmin-like complex, subunit 5
    Hs.7426  [show with all ESTs]
    Unigene Representative Sequence: NM_015302
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000587439 ENST00000588570 ENST00000585968 ENST00000424522 ENST00000203166(uc002oam.1)
    ENST00000592291 ENST00000428854 ENST00000430749 ENST00000590994 ENST00000379045

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HAUS5 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate HAUS5:
    hsa-miR-185 hsa-miR-4306 hsa-miR-708* hsa-miR-4276 hsa-miR-488 hsa-miR-3907 hsa-miR-628-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for HAUS5
    Predesigned siRNA for gene silencing in human, mouse, rat HAUS5
    Clone
    Products:
         
    OriGene clones in human, mouse for HAUS5 (see all 7)
    OriGene ORF clones in mouse, rat for HAUS5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HAUS5 (NM_015302)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HAUS5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAUS5
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for HAUS5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HAUS5
      QuantiTect SYBR Green Assays in human, mouse, rat HAUS5
      QuantiFast Probe-based Assays in human, mouse, rat HAUS5

    Additional mRNA sequence: 

    AB020648.1 AK307703.1 BC013947.2 BC064390.1 BC157882.1 BC171905.1 

    11 DOTS entries:

    DT.111899  DT.99969713  DT.95275970  DT.91733501  DT.40247937  DT.91661025  DT.91722573  DT.91733502 
    DT.95298496  DT.95275969  DT.97840591 

    Selected AceView cDNA sequences (see all 89):

    AA845355 BM978029 BM713814 BP873088 AI435198 AB020648 BC013947 BM561877 
    BC064390 BE302363 AA831485 F08287 BQ721933 BQ052963 BX342106 BF724721 
    AI886619 BU931401 BG252866 BI334258 CD656170 BU553241 BU149621 BE292864 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HAUS5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAAAGGCCCT
    HAUS5 Expression
    About this image

    HAUS5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HAUS5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.7426
        Custom PCR Arrays for HAUS5
    Primer
    Products:
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    QuantiFast Probe-based Assays in human, mouse, rat HAUS5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAUS5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HAUS5 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Haus51 , 5 HAUS augmin-like complex, subunit 51, 5 78.51(n)1
    73.02(a)1
      7 (18.95 cM)5
    719091  NM_027999.11  NP_082275.11 
     306537115 
    lizard
    (Anolis carolinensis)
    Reptilia HAUS56
    HAUS augmin-like complex, subunit 5
    33(a)
    1 ↔ 1
    GL343514.1(390268-411970)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1001457141 uncharacterized LOC100145714 46.96(n)
    34.85(a)
      100145714  NM_001127088.1  NP_001120560.1 
    zebrafish
    (Danio rerio)
    Actinopterygii haus51 HAUS augmin-like complex, subunit 5 43.09(n)
    29.26(a)
      492797  NM_001007438.1  NP_001007439.1 


    ENSEMBL Gene Tree for HAUS5 (if available)
    TreeFam Gene Tree for HAUS5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HAUS5 (see all 409)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs777863231,2
    C,F--36101667(+) GGTTTT/GGTTTT 1 -- us2k13Minor allele frequency- G:0.05WA NA EA 358
    rs1865906561,2
    --36101754(+) CAACTG/TATCCT 1 -- us2k10--------
    rs1149016151,2
    F--36101791(+) GACTAC/AAAGCG 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs93048731,2
    C,F,A--36101795(+) ACAAGC/TGTGCA 1 -- us2k19Minor allele frequency- T:0.44NA WA CSA EA 369
    rs1910046241,2
    --36101845(+) ACAAGA/GTTTTG 1 -- us2k10--------
    rs1809502631,2
    --36102153(+) GCAGGG/TGTCTC 1 -- us2k10--------
    rs1857622281,2
    --36102222(+) GCAGGA/CGGTGA 1 -- us2k10--------
    rs126087641,2
    H--36102339(+) aggatC/Ttagat 1 -- us2k14Minor allele frequency- T:0.00NS EA 420
    rs1915059311,2
    --36102347(+) GATTGC/TGCACT 1 -- us2k10--------
    rs126087661,2
    C,F,H--36102365(+) agaatC/Ttaatg 1 -- us2k15Minor allele frequency- T:0.00NS EA NA 422

    HapMap Linkage Disequilibrium report for HAUS5 (36103646 - 36116251 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for HAUS5: --
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing HAUS5
    DNA2.0 Custom Variant and Variant Library Synthesis for HAUS5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613432    OMIM disorders: --


    HAUS5 for disorders           About GeneDecksing


    Export disorders for HAUS5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HAUS5 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with HAUS5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity. (PubMed id 19427217)1, 2, 3 Lawo S....Pelletier L. (Curr. Biol. 2009)
    2. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1998)
    3. The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. (PubMed id 19369198)1, 2 Uehara R....Goshima G. (Proc. Natl. Acad. Sci. U.S.A. 2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    6. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (J. Cell. Sci. 2012)
    7. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    8. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23354 HGNC: 29130 AceView: KIAA0841 Ensembl:ENSG00000249115 euGenes: HUgn23354
    ECgene: HAUS5 H-InvDB: HAUS5

    (According to HUGE)
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    HUGE: KIAA0841

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HAUS5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for HAUS5 gene:
    Search GeneIP for patents involving HAUS5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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