Aliases for HAUS5 Gene
External Ids for HAUS5 Gene
Previous HGNC Symbols for HAUS5 Gene
Previous GeneCards Identifiers for HAUS5 Gene
HAUS5 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
GeneCards Summary for HAUS5 Gene
HAUS5 (HAUS Augmin Like Complex Subunit 5) is a Protein Coding gene. Diseases associated with HAUS5 include Joubert Syndrome 1. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Organelle biogenesis and maintenance.
UniProtKB/Swiss-Prot for HAUS5 Gene
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.