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HAUS4 Gene

protein-coding   GIFtS: 47
GCID: GC14M023415

HAUS Augmin-Like Complex, Subunit 4

(Previous name: chromosome 14 open reading frame 94)
(Previous symbol: C14orf94)
  Search for HAUS4
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
HAUS Augmin-Like Complex, Subunit 41 2
C14orf941 2 3 5
Chromosome 14 Open Reading Frame 941
HAUS Augmin-Like Complex Subunit 42
Homologous To Augmin Subunits2

External Ids:    HGNC: 201631   Entrez Gene: 549302   Ensembl: ENSG000000920367   OMIM: 6134315   UniProtKB: Q9H6D73   

Export aliases for HAUS4 gene to outside databases

Previous GC identifers: GC14M022486 GC14M003533


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HAUS4 Gene:
This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein
localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of
centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A
pseudogene of this gene is found on chromosome 1. (provided by RefSeq, Oct 2009)

GeneCards Summary for HAUS4 Gene:
HAUS4 (HAUS augmin-like complex, subunit 4) is a protein-coding gene. An important paralog of this gene is ENSG00000259132.

UniProtKB/Swiss-Prot: HAUS4_HUMAN, Q9H6D7
Function: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of
cytokinesis as part of the HAUS augmin-like complex




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the HAUS4 gene promoter:
         GR   AML1a   Tal-1   Pax-2   POU6F1 (c2)   FOXL1   E47   AREB6   Pax-2b   GR-alpha   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for HAUS4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HAUS4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q11.2   HGNC cytogenetic band: 14q11.1

HAUS4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HAUS4 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M023415:  view genomic region     (about GC identifiers)

Start:
23,415,437 bp from pter      End:
23,426,370 bp from pter
Size:
10,934 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HAUS4_HUMAN, Q9H6D7 (See protein sequence)
Recommended Name: HAUS augmin-like complex subunit 4  
Size: 363 amino acids; 42400 Da
Subunit: Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and
this interaction is required for spindle assembly
Sequence caution: Sequence=CAD62584.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B7WP17 D3DS34 Q86T15 Q86T16 Q86U43 Q9NX59
Alternative splicing: 4 isoforms:  Q9H6D7-1   Q9H6D7-2   Q9H6D7-3   Q9H6D7-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for HAUS4: NX_Q9H6D7

Explore proteomics data for HAUS4 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys201, Lys360
  • Modification sites at PhosphoSitePlus

  • See HAUS4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001159741.1  NP_001159742.1  NP_060285.2  

    ENSEMBL proteins: 
     ENSP00000452260   ENSP00000206474   ENSP00000342776   ENSP00000343473   ENSP00000452239  
     ENSP00000451018   ENSP00000450542   ENSP00000452165   ENSP00000452595   ENSP00000452261  
     ENSP00000452058   ENSP00000450612   ENSP00000450680   ENSP00000441026   ENSP00000380556  

    HAUS4 Human Recombinant Protein Products:

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    Novus Biologicals HAUS4 Lysates
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    Cloud-Clone Corp. Proteins for HAUS4

     
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    Search eBioscience for ELISAs for HAUS4 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    HAUS: HAUS augmin-like complex subunits

    1 InterPro protein domain:
     IPR026214 HAUS4

    Graphical View of Domain Structure for InterPro Entry Q9H6D7

    ProtoNet protein and cluster: Q9H6D7

    UniProtKB/Swiss-Prot: HAUS4_HUMAN, Q9H6D7
    Similarity: Belongs to the HAUS4 family


    Find genes that share domains with HAUS4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HAUS4_HUMAN, Q9H6D7
    Function: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of
    cytokinesis as part of the HAUS augmin-like complex

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    Find genes that share ontologies with HAUS4           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for HAUS4:
     Increased cell number in G2M,   Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HAUS4
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HAUS4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HAUS4

    miRNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HAUS4

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    GenScript: all cDNA clones in your preferred vector (see all 3): HAUS4 (NM_017815)
    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAUS4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HAUS4_HUMAN, Q9H6D7: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton,
    spindle. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol3
    nucleus2
    mitochondrion1
    plasma membrane1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome IDA--
    GO:0005819spindle IEA--
    GO:0005874microtubule IEA--
    GO:0070652HAUS complex IDA19369198

    Find genes that share ontologies with HAUS4           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HAUS4
    Interactions:

        Search GeneGlobe Interaction Network for HAUS4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for HAUS4 (Q9H6D73 ENSP000002064744) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HAUS1Q96CS23, ENSP000002820584I2D: score=1 STRING: ENSP00000282058
    HAUS2Q9NVX03, ENSP000002603724I2D: score=1 STRING: ENSP00000260372
    HAUS3Q68CZ63, ENSP000002437064I2D: score=1 STRING: ENSP00000243706
    HAUS6Q7Z4H73, ENSP000003698714I2D: score=1 STRING: ENSP00000369871
    HAUS8Q9BT253, ENSP000002536694I2D: score=1 STRING: ENSP00000253669
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis IEA--
    GO:0051225spindle assembly IMP19369198
    GO:0051297centrosome organization IMP19427217

    Find genes that share ontologies with HAUS4           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HAUS4



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HAUS4 gene (3 alternative transcripts): 
    NM_001166269.1  NM_001166270.1  NM_017815.2  

    Unigene Cluster for HAUS4:

    HAUS augmin-like complex, subunit 4
    Hs.442782  [show with all ESTs]
    Unigene Representative Sequence: NM_001166269
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22):
    ENST00000490506 ENST00000206474(uc001who.3 uc001wht.3 uc001whu.3)
    ENST00000554446 ENST00000342454 ENST00000347758(uc001whq.3) ENST00000555367
    ENST00000555986 ENST00000556421 ENST00000553859 ENST00000554063 ENST00000555040
    ENST00000556915 ENST00000554349 ENST00000553794 ENST00000554373 ENST00000554651
    ENST00000554516 ENST00000557591
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HAUS4 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate HAUS4
    SwitchGear 3'UTR luciferase reporter plasmidHAUS4 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HAUS4
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 3): HAUS4 (NM_017815)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HAUS4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAUS4
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HAUS4
      QuantiTect SYBR Green Assays in human, mouse, rat HAUS4
      QuantiFast Probe-based Assays in human, mouse, rat HAUS4

    Additional mRNA sequence: 

    AK000431.1 AK026016.1 AK057779.1 AY927599.1 BC001916.1 BC002554.2 BX247981.1 BX247995.1 
    BX248256.1 

    20 DOTS entries:

    DT.100768911  DT.100709232  DT.97785708  DT.100756937  DT.100770457  DT.114478  DT.92443409  DT.100886815 
    DT.211351  DT.100886817  DT.101987978  DT.100805473  DT.100886811  DT.100886820  DT.95230280  DT.100886823 
    DT.91929390  DT.92443403  DT.95142964  DT.211349 

    Selected AceView cDNA sequences (see all 384):

    BX247995 BP340581 AA262271 BX429871 BE256561 AI675271 CR620038 BX247981 
    AI192277 BM809071 AW028524 BQ929093 BQ921790 AA483303 CR607287 BQ881488 
    BQ881901 BQ894359 BX326192 BQ710698 CA308858 BQ925530 BC001916 AW675481 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for HAUS4 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b
    SP1:                                -                                         -                                                   
    SP2:                          -     -                                         -                                                   
    SP3:                          -     -                                   -     -                                                   
    SP4:                                -           -                             -                                                   
    SP5:                                                                    -     -                 -     -                           


    ECgene alternative splicing isoforms for HAUS4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HAUS4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTTCTGCAT
    HAUS4 Expression
    About this image


    HAUS4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 7 entries
             Zeugopod Long Bone
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             Meckel's Cartilage
     
     Limb (Muscoskeletal System)
             Pelvic Girdle
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
    HAUS4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HAUS4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.442782
        Custom PCR Arrays for HAUS4
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    QuantiFast Probe-based Assays in human, mouse, rat HAUS4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAUS4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for HAUS4 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Haus41 , 5 HAUS augmin-like complex, subunit 41, 5 81.63(n)1
    78.24(a)1
      14 (27.83 cM)5
    2190721  NM_145462.21  NP_663437.21 
     545417855 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    27(a)
    1 → many
    JH375696.1(3433-8527)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    47(a)
    1 → many
    GL343879.1(85706-98396)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia haus41 HAUS augmin-like complex, subunit 4 55.2(n)
    45.59(a)
      100488910  XM_002941512.2  XP_002941558.1 
    zebrafish
    (Danio rerio)
    Actinopterygii haus41 HAUS augmin-like complex, subunit 4 49.14(n)
    35.14(a)
      436698  NM_001002425.1  NP_001002425.1 


    ENSEMBL Gene Tree for HAUS4 (if available)
    TreeFam Gene Tree for HAUS4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HAUS4 gene
    ENSG000002591322  

    Find genes that share paralogs with HAUS4           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for HAUS4
    PGOHUM00000244329


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HAUS4 (see all 241)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1832842581,2
    --3546077(+) CATCTG/TTTACA 3 -- us2k10--------
    rs1446205021,2
    --23415047(+) CTGGTC/GTCGAA 3 -- ds50010--------
    rs1176779161,2
    C,F--23415178(+) AAAATA/GGTTCC 3 -- ds50011Minor allele frequency- G:0.03NA 120
    rs1385210301,2
    --23415258(+) ACTGTA/CCTCTT 3 -- ds50010--------
    rs1116200321,2
    C--23415529(+) TAAAT-/CTCCTTGC 3 -- cds11Minor allele frequency- CTC:0.00CSA 2
    rs30796941,2
    C--23415531(+) AATCT-/CCTTGCTA 3 -- cds10--------
    rs1808572931,2
    --23415610(+) GTGTTC/TCAAGC 3 -- ut310--------
    rs1400604101,2
    C--23415654(+) AGCCCC/GAGGTG 3 -- ut310--------
    rs1995343111,2
    C--23415729(+) CTGCCA/GGAGCT 3 -- ut310--------
    rs751881451,2
    C,F--23415733(+) CAGAGC/TTCAAC 3 -- ut313Minor allele frequency- T:0.02WA NA EU 5985

    HapMap Linkage Disequilibrium report for HAUS4 (23415437 - 23426370 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for HAUS4: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HAUS4
    DNA2.0 Custom Variant and Variant Library Synthesis for HAUS4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613431    OMIM disorders: --


    Find genes that share disorders with HAUS4           About GenesLikeMe


    Export disorders for HAUS4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HAUS4 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with HAUS4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity. (PubMed id 19427217)1, 2, 3 Lawo S....Pelletier L. (Curr. Biol. 2009)
    2. The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. (PubMed id 19369198)1, 2 Uehara R....Goshima G. (Proc. Natl. Acad. Sci. U.S.A. 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase. (PubMed id 23277564)1 Delker R.K....Papavasiliou F.N. (Proc. Natl. Acad. Sci. U.S.A. 2013)
    6. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54930 HGNC: 20163 AceView: C14orf94 Ensembl:ENSG00000092036 euGenes: HUgn54930
    ECgene: HAUS4 H-InvDB: HAUS4

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HAUS4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HAUS4 gene:
    Search GeneIP for patents involving HAUS4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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