Aliases for HAUS4 Gene
External Ids for HAUS4 Gene
Previous HGNC Symbols for HAUS4 Gene
Previous GeneCards Identifiers for HAUS4 Gene
This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
GeneCards Summary for HAUS4 Gene
HAUS4 (HAUS Augmin Like Complex Subunit 4) is a Protein Coding gene. Diseases associated with HAUS4 include Joubert Syndrome 1. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Organelle biogenesis and maintenance. An important paralog of this gene is ENSG00000259132.
UniProtKB/Swiss-Prot for HAUS4 Gene
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.