Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HAUS4 Gene

protein-coding   GIFtS: 45
GCID: GC14M023415

HAUS Augmin-Like Complex, Subunit 4

(Previous name: chromosome 14 open reading frame 94)
(Previous symbol: C14orf94)
  Search for HAUS4
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
HAUS Augmin-Like Complex, Subunit 41 2
C14orf941 2 3 5
Chromosome 14 Open Reading Frame 941
HAUS Augmin-Like Complex Subunit 42
Homologous To Augmin Subunits2

External Ids:    HGNC: 201631   Entrez Gene: 549302   Ensembl: ENSG000000920367   OMIM: 6134315   UniProtKB: Q9H6D73   

Export aliases for HAUS4 gene to outside databases

Previous GC identifers: GC14M022486 GC14M003533


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HAUS4 Gene:
This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein
localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of
centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A
pseudogene of this gene is found on chromosome 1. (provided by RefSeq, Oct 2009)

GeneCards Summary for HAUS4 Gene: 
HAUS4 (HAUS augmin-like complex, subunit 4) is a protein-coding gene. GO annotations related to this gene include molecular_function. An important paralog of this gene is ENSG00000259132.

UniProtKB/Swiss-Prot: HAUS4_HUMAN, Q9H6D7
Function: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of
cytokinesis as part of the HAUS augmin-like complex




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  NC_018925.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HAUS4 gene promoter:
         GR   AML1a   Tal-1   Pax-2   POU6F1 (c2)   FOXL1   E47   AREB6   Pax-2b   GR-alpha   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for HAUS4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HAUS4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q11.2   HGNC cytogenetic band: 14q11.1

HAUS4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HAUS4 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M023415:  view genomic region     (about GC identifiers)

Start:
23,415,437 bp from pter      End:
23,426,370 bp from pter
Size:
10,934 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HAUS4_HUMAN, Q9H6D7 (See protein sequence)
Recommended Name: HAUS augmin-like complex subunit 4  
Size: 363 amino acids; 42400 Da
Subunit: Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and
this interaction is required for spindle assembly
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton,
spindle. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules
Sequence caution: Sequence=CAD62584.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B7WP17 D3DS34 Q86T15 Q86T16 Q86U43 Q9NX59
Alternative splicing: 4 isoforms:  Q9H6D7-1   Q9H6D7-2   Q9H6D7-3   Q9H6D7-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for HAUS4: NX_Q9H6D7

Explore proteomics data for HAUS4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H6D7

  • HAUS4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HAUS4 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001159741.1  NP_001159742.1  NP_060285.2  

    ENSEMBL proteins: 
     ENSP00000452260   ENSP00000206474   ENSP00000342776   ENSP00000343473   ENSP00000452239  
     ENSP00000451018   ENSP00000450542   ENSP00000452165   ENSP00000452595   ENSP00000452261  
     ENSP00000452058   ENSP00000450612   ENSP00000450680   ENSP00000441026   ENSP00000380556  

    Human Recombinant Protein Products for HAUS4: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for HAUS4
    OriGene Protein Over-expression Lysate for HAUS4
    OriGene MassSpec for HAUS4 
    OriGene Custom Protein Services for HAUS4
    GenScript Custom Purified and Recombinant Proteins Services for HAUS4
    Novus Biologicals HAUS4 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HAUS4 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome IDA--
    GO:0005819spindle IEA--
    GO:0005874microtubule IEA--
    GO:0070652HAUS complex IDA19369198

    HAUS4 for ontologies           About GeneDecksing



    HAUS4 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for HAUS4
    GenScript Custom Superior Antibodies Services for HAUS4
    Novus Biologicals HAUS4 Antibodies
    Abcam antibodies for HAUS4
    Cloud-Clone Corp. Antibodies for HAUS4 
    ThermoFisher Antibodies for HAUS4
    LSBio Antibodies in human, mouse, rat for HAUS4 

    Assay Products for HAUS4: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for HAUS4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for HAUS4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for HAUS4 
    Cloud-Clone Corp. CLIAs for HAUS4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    HAUS: HAUS augmin-like complex subunits

    1 InterPro protein domain:
     IPR026214 HAUS4

    Graphical View of Domain Structure for InterPro Entry Q9H6D7

    ProtoNet protein and cluster: Q9H6D7

    UniProtKB/Swiss-Prot: HAUS4_HUMAN, Q9H6D7
    Similarity: Belongs to the HAUS4 family


    HAUS4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HAUS4_HUMAN, Q9H6D7
    Function: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of
    cytokinesis as part of the HAUS augmin-like complex

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    HAUS4 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for HAUS4:
     Increased cell number in G2M,   Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for HAUS4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HAUS4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HAUS4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HAUS4 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HAUS4
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate HAUS4
    SwitchGear 3'UTR luciferase reporter plasmidHAUS4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for HAUS4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HAUS4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for HAUS4
    Sirion Biotech Customized adenovirus for overexpression of HAUS4

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for HAUS4 (see all 16)
    OriGene ORF clones in mouse, rat for HAUS4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): HAUS4 (NM_017815)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HAUS4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAUS4
    Sirion Biotech Customized lentivirus for stable overexpression of HAUS4 
                         Customized lentivirus expression plasmids for stable overexpression of HAUS4 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for HAUS4
    Search LifeMap BioReagents cell lines for HAUS4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAUS4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HAUS4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/9 Interacting proteins for HAUS4 (Q9H6D73 ENSP000002064744) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HAUS1Q96CS23, ENSP000002820584I2D: score=1 STRING: ENSP00000282058
    HAUS2Q9NVX03, ENSP000002603724I2D: score=1 STRING: ENSP00000260372
    HAUS3Q68CZ63, ENSP000002437064I2D: score=1 STRING: ENSP00000243706
    HAUS6Q7Z4H73, ENSP000003698714I2D: score=1 STRING: ENSP00000369871
    HAUS7Q998713, ENSP000003592394I2D: score=1 STRING: ENSP00000359239
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis IEA--
    GO:0051225spindle assembly IMP19369198
    GO:0051297centrosome organization IMP19427217
    GO:0051301cell division IEA--

    HAUS4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HAUS4

    Search CenterWatch for drugs/clinical trials and news about HAUS4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HAUS4 gene (3 alternative transcripts): 
    NM_001166269.1  NM_001166270.1  NM_017815.2  

    Unigene Clusters for HAUS4:

    HAUS augmin-like complex, subunit 4
    Hs.442782  [show with all ESTs], Hs.727321  [show with all ESTs]
    Unigene Representative Sequences: NM_001166269, AK097980
    18/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22):
    ENST00000490506 ENST00000206474(uc001who.3 uc001wht.3 uc001whu.3)
    ENST00000554446 ENST00000342454 ENST00000347758(uc001whq.3) ENST00000555367
    ENST00000555986 ENST00000556421 ENST00000553859 ENST00000554063 ENST00000555040
    ENST00000556915 ENST00000554349 ENST00000553794 ENST00000554373 ENST00000554651
    ENST00000554516 ENST00000557591
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HAUS4
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate HAUS4
    SwitchGear 3'UTR luciferase reporter plasmidHAUS4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for HAUS4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HAUS4
    Clone
    Products:
         
    OriGene clones in human, mouse for HAUS4 (see all 16)
    OriGene ORF clones in mouse, rat for HAUS4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): HAUS4 (NM_017815)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HAUS4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAUS4
    Sirion Biotech Customized lentivirus for stable overexpression of HAUS4 
                         Customized lentivirus expression plasmids for stable overexpression of HAUS4 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for HAUS4
    OriGene qSTAR qPCR primer pairs in human, mouse for HAUS4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HAUS4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAUS4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAUS4

    Additional mRNA sequence: AK097980.1 

    21 DOTS entries:

    DT.100768911  DT.100709232  DT.97785708  DT.100756937  DT.100770457  DT.114478  DT.92443409  DT.100886815 
    DT.211351  DT.100886817  DT.101987978  DT.100805473  DT.100886811  DT.100886820  DT.95230280  DT.211349 
    DT.100886823  DT.91929390  DT.92443403  DT.95142964  DT.120777857 

    24/384 AceView cDNA sequences (see all 384):

    AW439431 CR616246 CR621122 BX421885 BU855272 AA662066 BC002554 AI420789 
    BU618909 BQ877257 BQ921409 BM474645 BE256644 CR592027 AA809465 CB121611 
    AW439855 BF439697 BQ276336 BX347205 BM927574 BM670794 BQ877343 BQ939729 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for HAUS4 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b
    SP1:                                -                                         -                                                   
    SP2:                          -     -                                         -                                                   
    SP3:                          -     -                                   -     -                                                   
    SP4:                                -           -                             -                                                   
    SP5:                                                                    -     -                 -     -                           


    ECgene alternative splicing isoforms for HAUS4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HAUS4 expression in normal human tissues (normalized intensities)      HAUS4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTTCTGCAT
    HAUS4 Expression
    About this image


    HAUS4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/11 selected tissues (see all 11) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 12 entries
             Zeugopod Long Bone
             skeleton/pectoral girdle and thoracic body wall/sternum   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 5 entries
             Meckel's Cartilage
             sensory organ/ear/inner ear   
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 3 entries
             skeleton/cranium/chondrocranium   
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Nose (Sensory Organs)
             sensory organ/nose/naris   

    See HAUS4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HAUS4

    SOURCE GeneReport for Unigene clusters: Hs.442782 Hs.727321
        SABiosciences Custom PCR Arrays for HAUS4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for HAUS4
    OriGene qSTAR qPCR primer pairs in human, mouse for HAUS4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HAUS4
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAUS4
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAUS4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAUS4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for HAUS4 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Haus41 , 5 HAUS augmin-like complex, subunit 41, 5 81.63(n)1
    78.24(a)1
      14 (27.83 cM)5
    2190721  NM_145462.21  NP_663437.21 
     545417855 
    chicken
    (Gallus gallus)
    Aves --
    --
    27(a)
    1 → many
    JH375696.1(3433-8527)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    47(a)
    1 → many
    GL343879.1(85706-98396)
    zebrafish
    (Danio rerio)
    Actinopterygii haus41 HAUS augmin-like complex, subunit 4 49.24(n)
    35.14(a)
      436698  NM_001002425.1  NP_001002425.1 


    ENSEMBL Gene Tree for HAUS4 (if available)
    TreeFam Gene Tree for HAUS4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HAUS4 gene
    ENSG000002591322  

    HAUS4 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for HAUS4
    PGOHUM00000244329


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/241 SNPs in HAUS4 are shown (see all 241)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1832842581,2
    --3546077(+) CATCTG/TTTACA 3 -- us2k10--------
    rs1446205021,2
    --23415047(+) CTGGTC/GTCGAA 3 -- ds50010--------
    rs1176779161,2
    C,F--23415178(+) AAAATA/GGTTCC 3 -- ds50011Minor allele frequency- G:0.03NA 120
    rs1385210301,2
    --23415258(+) ACTGTA/CCTCTT 3 -- ds50010--------
    rs1116200321,2
    C--23415529(+) TAAAT-/CTCCTTGC 3 -- cds11Minor allele frequency- CTC:0.00CSA 2
    rs30796941,2
    C--23415531(+) AATCT-/CCTTGCTA 3 -- cds10--------
    rs1808572931,2
    --23415610(+) GTGTTC/TCAAGC 3 -- ut310--------
    rs1400604101,2
    C--23415654(+) AGCCCC/GAGGTG 3 -- ut310--------
    rs1995343111,2
    C--23415729(+) CTGCCA/GGAGCT 3 -- ut310--------
    rs751881451,2
    C,F--23415733(+) CAGAGC/TTCAAC 3 -- ut313Minor allele frequency- T:0.02WA NA EU 5985

    HapMap Linkage Disequilibrium report for HAUS4 (23415437 - 23426370 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for HAUS4: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing HAUS4
    DNA2.0 Custom Variant and Variant Library Synthesis for HAUS4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    HAUS4 for disorders           About MalaCards
    OMIM gene information: 613431    OMIM disorders: --


    HAUS4 for disorders           About GeneDecksing


    Export disorders for HAUS4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HAUS4 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with HAUS4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity. (PubMed id 19427217)1, 2, 3 Lawo S....Pelletier L. (2009)
    2. The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. (PubMed id 19369198)1, 2 Uehara R....Goshima G. (2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase. (PubMed id 23277564)1 Delker R.K....Papavasiliou F.N. (2013)
    6. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54930 HGNC: 20163 AceView: C14orf94 Ensembl:ENSG00000092036 euGenes: HUgn54930
    ECgene: HAUS4 H-InvDB: HAUS4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HAUS4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HAUS4 gene:
    Search GeneIP for patents involving HAUS4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for HAUS4  
     OriGene qPCR primer pairs and template standards for HAUS4   OriGene Protein Over-expression Lysate for HAUS4  
     OriGene MassSpec something-or-other for HAUS4   OriGene clones in human, mouse for HAUS4  
     OriGene qSTAR qPCR primer pairs in human, mouse for HAUS4   OriGene Purified Protein for HAUS4  
     OriGene ORF clones in mouse, rat for HAUS4   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for HAUS4   OriGene Custom Protein Services for HAUS4  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HAUS4
     QIAGEN SeqTarget long-range PCR primers for resequencing HAUS4
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HAUS4
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HAUS4
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAUS4
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAUS4
     GenScript Custom Purified and Recombinant Proteins Services for HAUS4 GenScript cDNA clones with any tag delivered in your preferred vector for HAUS4
     GenScript Custom Assay Services for HAUS4 GenScript Custom Superior Antibodies Services for HAUS4
     GenScript Custom overexpressing Cell Line Services for HAUS4 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in HAUS4 promoter
     Search Chromatin IP Primers for HAUS4
     RT2 qPCR Primer Assay in human, mouse, rat HAUS4
     Search GNC Networks for HAUS4
     SABiosciences Custom PCR Arrays for HAUS4
     Search Tocris compounds for HAUS4
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     HAUS4 antibodies
     HAUS4 lysates
     Antibodies for HAUS4
     See all of Abcam's Antibodies, Kits and Proteins for HAUS4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for HAUS4
     Antibodies for HAUS4
     ELISAs for HAUS4
     CLIAs for HAUS4
     Search LifeMap BioReagents cell lines for HAUS4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAUS4
     SwitchGear 3'UTR luciferase reporter plasmids for HAUS4
     Browse SwitchGear Promoter luciferase reporter plasmids for HAUS4
     ThermoFisher Antibodies for HAUS4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAUS4
     inGenious Targeting Laboratory - Custom generated mouse model solutions for HAUS4
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HAUS4
    Customized:
     lentivirus for stable overexpression of HAUS4
     lentivirus expression plasmids for stable overexpression of HAUS4
     adenovirus for overexpression of HAUS4
     LSBio Antibodies in human, mouse, rat for HAUS4
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      HAUS4 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4