Aliases for HAUS1 Gene
External Ids for HAUS1 Gene
Previous HGNC Symbols for HAUS1 Gene
Previous GeneCards Identifiers for HAUS1 Gene
HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
GeneCards Summary for HAUS1 Gene
HAUS1 (HAUS Augmin Like Complex Subunit 1) is a Protein Coding gene. Diseases associated with HAUS1 include Miller-Dieker Lissencephaly Syndrome. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Organelle biogenesis and maintenance.
UniProtKB/Swiss-Prot for HAUS1 Gene
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.