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HAT1 Gene

protein-coding   GIFtS: 66

GC02P172487
histone acetyltransferase 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for HAT1

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
EC 2.3.1.48 3
KAT1 1, 2
Descriptions
histone acetyltransferase 1 2
External Ids
HGNC: 48211
Entrez Gene: 85202
UniProtKB: O149293
Ensembl: ENSG000001287087
Search outside databases for aliases for HAT1 gene

Previous GC identifers: GC02P170830 GC02P171320 GC02P172742 GC02P172981 GC02P172604

Summaries
for HAT1

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for HAT1:
Histone acetylation, particularly of histone H4, plays an important role in replication-dependent
chromatin assembly. This gene encodes a histone acetylase that contains A, B, and D motifs,
present in many N-acetyltransferases, including those that acetylate substrates other than
histones. Alternatively spliced transcript variants that encode different isoforms have been
identified for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: HAT1_HUMAN, O14929
Function: May play a role in telomeric silencing. Acetylates soluble but not nucleosomal H4 at
'Lys-5' and 'Lys-12' and acetylates histone H2A at 'Lys-5'. HAT1 has intrinsic substrate
specificity that modifies lysine in recognition sequence GXGKXG

Genomic Location
for HAT1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the HAT1 gene  

Entrez Gene cytogenetic band: 2q31.2-q33.1   Ensembl cytogenetic band:  2q31.1   HGNC cytogenetic band: 2q31.2-q33.1

HAT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P172487:     (about GC identifiers)

Start:
 172,487,204 bp from pter
End:
 172,556,846 bp from pter
Size:
 69,643 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000002.10  NT_005403.16  

Proteins
for HAT1

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: HAT1_HUMAN, O14929 (See protein sequence)
Recommended Name: Histone acetyltransferase type B catalytic subunit  
Size: 419 amino acids; 49513 Da
Subunit: Heteromer of HAT1 and p46/HAT2 subunits
Subcellular location: Nucleus. Cytoplasm. Note=Nuclear in S-phase cells and cytoplasmic
PDB structures from and Proteopedia :
2P0W (3D)    
Secondary accessions: Q49A44 Q53QF0 Q53SU4

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (2 alternative transcripts): 
    NP_001028257.1  NP_003633.1  


    ENSEMBL proteins: 
    ENSP00000264108 ENSP00000376363 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Millipore Purified and/or Recombinant HAT1 Protein
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Histone acetyltransferase, KAT1 / HAT1)
    Human Recombinant Proteins from Abnova (HAT1)
                  OriGene Purified Recombinant Human Protein: HAT1 

    2 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus TAS9427644
    GO:0005737 cytoplasm IEA--
    About this table

    Antibodies for HAT1: 
    Browse Antibodies Central at Invitrogen
    Millipore Mono- and Polyclonal Antibodies for the study of HAT1
    Sigma-Aldrich Antibody Arrays and Antibodies for HAT1
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (Histone acetyltransferase, KAT1 / HAT1), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (HAT1)
    Novus Biologicals Antibody for HAT1

    Assays for HAT1: 
    Browse Invitrogen for biochemical assays
    Millipore Kits and Assays for the Analysis of HAT1
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for HAT1

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro domains/families:
     IPR017380 Hist_AcTrfase_B-typ_cat-su
     IPR016181 Acyl_CoA_acyltransferase
     IPR019467 Hat1_N


       GeneDecks  HAT1 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry O14929

    ProtoNet protein and cluster: O14929

    UniProtKB/Swiss-Prot: HAT1_HUMAN, O14929
    Similarity: Belongs to the HAT1 family

    Gene Function
    for HAT1

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (HAT1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (HAT1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001033085

                  Applied Biosystems Silencer® siRNAs for HAT1

                  Sigma-Aldrich siRNA for HAT1  
                         Sigma-Aldrich shRNA for HAT1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for HAT1
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001033085
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001033085
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_001033085 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_003642

    UniProtKB/Swiss-Prot: HAT1_HUMAN, O14929
    Function: May play a role in telomeric silencing. Acetylates soluble but not nucleosomal H4 at
    'Lys-5' and 'Lys-12' and acetylates histone H2A at 'Lys-5'. HAT1 has intrinsic substrate
    specificity that modifies lysine in recognition sequence GXGKXG
    Catalytic activity: Acetyl-CoA + histone = CoA + acetylhistone
    Enzyme Number (IUBMB): EC 2.3.1.48 

    Genatlas biochemistry entry for HAT1:
    histone actyltransferase 1,catalytic subunit,acetylating soluble (not nucleosomal) newly
    synthesized histone H4 at Lys5 and Lys12,and H2A at Lys5,expressed in the nucleus of S-phase
    cells,likely involved in generating modified H4 required for replication-dependent chromatin
    remodeling

    4 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004402 histone acetyltransferase activity TAS9427644
    GO:0005515 protein binding TAS9427644
    GO:0008415 acyltransferase activity IEA--
    GO:0016740 transferase activity IEA--
    About this table

    Pathways & Interactions
    for HAT1

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Millipore Pathway for HAT1
     Histone modification

       GeneDecks  HAT1 for the pathways selected above  
    About GeneDecksing

    2 Sigma-Aldrich "Your Favorite Gene" Pathways for  HAT1  (Your Favorite Gene powered by Ingenuity) 
     HMGB1 Signaling
     Molecular Mechanisms of Cancer

       GeneDecks  HAT1 for the pathways selected above  
    About GeneDecksing


    5/18 Interacting proteins for HAT1 (O149292 ENSP000002641083) via UniProtKB, MINT, and/or STRING (see all 18 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAZP631042MINT-3296639
    HDAC1ENSP000003626493STRING (score=.895)
    HDAC3ENSP000003029673STRING (score=.89)
    AASDHPPTENSP000002786183STRING (score=.877)
    HDAC9ENSP000002620693STRING (score=.864)
    About this table

    5 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006323 DNA packaging TAS9427644
    GO:0006348 chromatin silencing at telomere IEA--
    GO:0006475 internal protein amino acid acetylation TAS9427644
    GO:0016568 chromatin modification IEA--
    GO:0016573 histone acetylation IEA--
    About this table

    Drugs & Compounds
    for HAT1

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Enzo Life Sciences drugs & compounds for HAT1
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for HAT1
    1 Novoseek chemical compound relationship for HAT1 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    lysine 45.05 1 12417736 (1)
    About this table

    2 PharmGKB drug compound relationships for HAT1 gene
    Drug compound PharmGKB Relations PubMed IDs for articles supporting these relationships
    mercaptopurinePD  FA  GN  12704389
    methotrexatePD  FA  GN  12704389
    About this table


    Transcripts
    for HAT1

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (HAT1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (HAT1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001033085

                  Sigma-Aldrich siRNA for HAT1  
                         Sigma-Aldrich shRNA for HAT1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001033085  NM_003642  

    REFSEQ mRNAs for HAT1 gene (2 alternative transcripts): 

    NM_001033085.1   NM_003642.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001033085  NM_003642  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001033085
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001033085
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_001033085 

    Additional cDNA sequence: 

    AF030424.1 AK127840.1 AK309001.1 AK313699.1 BC018682.1 BC063003.1 CR592532.1 CR600659.1 
    CR608151.1 

    16 DOTS entries:

    DT.100649430  DT.455459  DT.100804890  DT.95244592  DT.97843891  DT.95171897  DT.101980132  DT.120943144 
    DT.101982935  DT.120943137  DT.75169363  DT.92435260  DT.91895216  DT.92435254  DT.95171900  DT.99935544 

    24/182 AceView cDNA sequences (see all 182 ):

    BP378277 AF030424 BI060057 CB114285 BX342229 CB160511 BM785196 AA022845 
    CB159313 AA342424 BC018682 AI220803 BM728899 AI810998 AA022969 AI784614 
    NM_003642 AI273170 CB136713 BM983029 AA580942 BM757795 CB119323 BQ030312 

    highest scoring ESTs for HAT1:

    AF030424 AA022969 AA044238 AA279643 AI801775 AI823664 AL562428 AL562662 AV719063 AV719181 

    Unigene Cluster for HAT1:

    Histone acetyltransferase 1
    Hs.632532  [show with all ESTs]
    Unigene Representative Sequence: AK127840


    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for HAT1 (see all 6 )

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b
    SP1:                          -     -                                                                                 
    SP2:                                                                                                                  
    SP3:                          -     -           -                                                                     
    SP4:                          -     -           -     -                                                               
    SP5:                                -                                                                                 

    About this scheme

    ECgene alternative splicing isoforms for HAT1

    2 Ensembl transcripts including schematic representations:
    ENST00000264108  ENST00000392584  

    Expression
    for HAT1

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    HAT1 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for HAT1

    1 / 2 / 3

    3 probe-sets matching HAT1 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    41855_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 AF030424 1.00 1.00 1.00 1

    		203138_at2, 3 U133-A 1 1.00 1.00 -- -- NM_003642 0.60 1.00 0.82 1

    		203138_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  HAT1 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: AACAGCTGGA

    SOURCE GeneReport for Unigene cluster: Hs.632532

    Expression variation in blood from EXPOLDB for HAT1

    Orthologs
    for HAT1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for HAT1 gene from 5/20 species (see all 20 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 LOC4787991   -- similar to histone aminotransferase 1 (predicted) 95.31(n)
    98.57(a)    		 478799  XM_844987.1  XP_850080.1 
    chimpanzee
    (Pan troglodytes)    		 LOC4597371   -- similar to histone acetyltransferase 1 99.84(n)
    100(a)    		 459737  XM_515904.2  XP_515904.1 
    cow
    (Bos taurus)    		 HAT11   -- histone acetyltransferase 1 95.64(n)
    98.31(a)    		 509329  NM_001034347.1  NP_001029519.1 
    rat
    (Rattus norvegicus)    		 Hat11   -- histone acetyltransferase 1 92.28(n)
    96.66(a)    		 296501  NM_001009657.1  NP_001009657.1 
    mouse
    (Mus musculus)    		 Hat11, 5 25
    		 histone aminotransferase 11, 5 91.47(n)1
    93.96(a)1    		 1074351  NM_026115.31  NP_080391.21 
     AA5369335  AI4145755  (see all 18)
    About this table        Species with no ortholog for HAT1

    ENSEMBL Gene Tree for HAT1

    Paralogs
    for HAT1

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    		  --

    SNPs/Variants
    for HAT1

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/274 NCBI SNPs in HAT1 are shown (see all 274 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 53)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 2 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    --
    rs42804271,2
    		A,C,F,H172521464(+) aacttG/Agatgt 2 -- int14Minor allele frequency- A:0.28EU EA WA 418
    rs101651261,2
    		A,C,F,H172528561(+) CTTCAT/CGTTAG 2 -- int116Minor allele frequency- C:0.49EA NA EU WA 1466
    rs104392961,2
    		A,C,F,H172536576(+) TGAAAT/CGCTCG 2 -- int112Minor allele frequency- C:0.20EU EA WA NA 1198
    rs67407051,2
    		A,C,F,H172505527(+) atacaC/Aagagg 2 -- int17Minor allele frequency- A:0.21EU EA WA NA 560
    --
    rs102028231,2
    		A,C,F,H172488378(+) CTCTCT/CACATT 2 -- int14Minor allele frequency- C:0.26EU EA WA 412
    rs14437001,2
    		A,C,F,H172554503(+) CATAAG/ATGACC 2 -- int19Minor allele frequency- A:0.19MN EU EA WA NA 964
    rs73405161,2
    		A,C,F,H172493960(+) ttgtcT/Ctttcc 2 -- int1 trp34Minor allele frequency- C:0.21EU EA WA 418
    rs67576801,2
    		A,C,F,H172523756(+) ATTTGG/TTTTTT 2 -- int14Minor allele frequency- T:0.21EU EA WA 416
    rs43242921,2
    		A,C,F,H172521491(+) ttatgG/Caaagt 2 -- int13Minor allele frequency- C:0.25EA WA 298
    --
    rs67500581,2
    		A,C,F,H172495155(+) ttctgG/Tgttcg 2 -- int14Minor allele frequency- T:0.23EU EA WA 396
    About this table

    HapMap Linkage Disequilibrium images for HAT1 (up to first 250kb)

    Disorders & Mutations
    for HAT1

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 603053

    1 PharmGKB disease relationship for HAT1 gene
    Disease PharmGKB Relations PubMed IDs for articles supporting these relationships
    Leukemia, Lymphocytic, Acute, L1PD  FA  GN  12704389
    About this table

    Human Genome Epidemiology Navigator: HAT1 (1 document)

    Medical News
    for HAT1

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for HAT1

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/24 PubMed articles for HAT1 gene (see all 24 ):

    Search for HAT1

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing HAT1

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 8520 HGNC: 4821 AceView: HAT1 Ensembl:ENSG00000128708 euGenes: HUgn8520
    ECgene: HAT1 H-InvDB: HAT1

    Other Databases showing HAT1

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing HAT1

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for HAT1 Genetics and Cytogenetics in Oncology and Haematology
    Wikipedia http://en.wikipedia.org/wiki/Histone_acetyltransferase

    Licensable Technologies
    for HAT1

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for HAT1

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for HAT1:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for HAT1-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for HAT1 Antibodies for HAT1
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for HAT1 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
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     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
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     Recombinant & Natural Proteins  

     Recombinant Proteins (HAT1)
     Antibodies (HAT1)
     Chimera RNAi (HAT1)
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (Histone acetyltransferase, KAT1 / HAT1)
     Antibodies (Histone acetyltransferase, KAT1 / HAT1)
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     Search Tocris compounds for HAT1




     Drugs for HAT1
     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for HAT1

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