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Aliases for HAS2-AS1 Gene

Subcategory (RNA class) for HAS2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for HAS2-AS1 Gene

  • HAS2 Antisense RNA 1 2 3 5
  • HAS2 Antisense RNA 1 (Non-Protein Coding) 2 3
  • Hyaluronan Synthase 2 Antisense 2 3
  • HAS2 Antisense RNA (Non-Protein Coding) 2
  • Non-Protein Coding RNA 77 2
  • NCRNA00077 3
  • HAS2-AS 3
  • HAS2AS 3
  • HASNT 3

External Ids for HAS2-AS1 Gene

Previous HGNC Symbols for HAS2-AS1 Gene

  • HAS2AS
  • HAS2-AS

Previous GeneCards Identifiers for HAS2-AS1 Gene

  • GC08P122651

Summaries for HAS2-AS1 Gene

GeneCards Summary for HAS2-AS1 Gene

HAS2-AS1 (HAS2 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HAS2-AS1 Gene

Genomics for HAS2-AS1 Gene

Regulatory Elements for HAS2-AS1 Gene

Enhancers for HAS2-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F121821 0.4 ENCODE 11.5 +183.6 183586 1.9 PKNOX1 JUNB NR2F2 RELA ZNF316 ZNF207 EMSY EGR2 HAS2 HAS2-AS1 PIR59127 GC08P121847
GH08F121784 0.6 ENCODE 11 +145.3 145323 0.2 BHLHE40 FOXP2 NR2F2 HAS2 HAS2-AS1 PIR59127 GC08M121742
GH08F120932 0.9 Ensembl ENCODE 6.9 -706.0 -705958 2.2 ELF3 ZNF792 SAP130 MLX CEBPG RAD21 ZNF644 ZNF7 TEAD3 HOMEZ MRPL13 MTBP SNTB1 HAS2-AS1 ENSG00000253619 LOC100133147
GH08F121637 0.8 ENCODE 0.8 +1.5 1496 6.2 ATF1 SIN3A YBX1 RAD21 GLIS2 ZNF366 SCRT2 ZNF143 CREM EGR2 LOC105375732 HAS2 HAS2-AS1
GH08F121636 0.2 Ensembl 0.8 -2.4 -2393 0.2 HAS2-AS1 GC08P121551
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around HAS2-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for HAS2-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001400290 1107 4801 ATF1 SIN3A FEZF1 RAD21 GLIS2 ZNF366 SCRT2 ZNF143 CREM EGR2

Genomic Location for HAS2-AS1 Gene

Chromosome:
8
Start:
121,639,293 bp from pter
End:
121,645,325 bp from pter
Size:
6,033 bases
Orientation:
Plus strand

Genomic View for HAS2-AS1 Gene

Genes around HAS2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HAS2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HAS2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HAS2-AS1 Gene

Proteins for HAS2-AS1 Gene

Post-translational modifications for HAS2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HAS2-AS1 Gene

Domains & Families for HAS2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HAS2-AS1 Gene

Function for HAS2-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HAS2-AS1 Gene

Localization for HAS2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HAS2-AS1 Gene

Pathways & Interactions for HAS2-AS1 Gene

SuperPathways for HAS2-AS1 Gene

No Data Available

Interacting Proteins for HAS2-AS1 Gene

Gene Ontology (GO) - Biological Process for HAS2-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HAS2-AS1 Gene

Transcripts for HAS2-AS1 Gene

mRNA/cDNA for HAS2-AS1 Gene

(2) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HAS2-AS1 Gene

HAS2 antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HAS2-AS1 Gene

No ASD Table

Relevant External Links for HAS2-AS1 Gene

GeneLoc Exon Structure for
HAS2-AS1
ECgene alternative splicing isoforms for
HAS2-AS1

Expression for HAS2-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HAS2-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for HAS2-AS1 Gene

This gene is overexpressed in Testis (x9.2).

SOURCE GeneReport for Unigene cluster for HAS2-AS1 Gene:

Hs.668686
genes like me logo Genes that share expression patterns with HAS2-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for HAS2-AS1 Gene

Orthologs for HAS2-AS1 Gene

Evolution for HAS2-AS1 Gene

ENSEMBL:
Gene Tree for HAS2-AS1 (if available)
TreeFam:
Gene Tree for HAS2-AS1 (if available)

No data available for Orthologs for HAS2-AS1 Gene

Paralogs for HAS2-AS1 Gene

No data available for Paralogs for HAS2-AS1 Gene

Variants for HAS2-AS1 Gene

Sequence variations from dbSNP and Humsavar for HAS2-AS1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs10086278 -- 121,638,498(+) TTCTA(A/T)TTACC intron-variant, upstream-variant-2KB
rs10089164 -- 121,638,674(+) TGTCA(A/T)TGAAA intron-variant, upstream-variant-2KB
rs10102290 -- 121,638,598(+) GAATT(A/G)TCTGT intron-variant, upstream-variant-2KB
rs10106294 -- 121,645,368(+) TAACC(A/G)TTTAT downstream-variant-500B
rs1057308 -- 121,641,007(+) TTTAA(A/G)AAGGA intron-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for HAS2-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv1077067 CNV deletion 25765185
nsv831446 CNV loss 17160897

Relevant External Links for HAS2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HAS2-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HAS2-AS1 Gene

Disorders for HAS2-AS1 Gene

Relevant External Links for HAS2-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HAS2-AS1

No disorders were found for HAS2-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HAS2-AS1 Gene

Publications for HAS2-AS1 Gene

  1. Makin' sense of the antisense: HA expression and synthesis requires HAS2-AS1 and O-GlcNAcylation. (PMID: 25645084) Neill T. … Zoeller J. (Matrix Biol. 2015) 3 64
  2. Natural antisense transcript for hyaluronan synthase 2 (HAS2-AS1) induces transcription of HAS2 via protein O-GlcNAcylation. (PMID: 25183006) Vigetti D. … Passi A. (J. Biol. Chem. 2014) 3 64
  3. The human hyaluronan synthase 2 (HAS2) gene and its natural antisense RNA exhibit coordinated expression in the renal proximal tubular epithelial cell. (PMID: 21357421) Michael D.R. … Bowen T. (J. Biol. Chem. 2011) 3 64
  4. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PMID: 17903294) Yang Q. … O'Donnell C.J. (BMC Med. Genet. 2007) 3 64
  5. Natural antisense mRNAs to hyaluronan synthase 2 inhibit hyaluronan biosynthesis and cell proliferation. (PMID: 15843373) Chao H. … Spicer A.P. (J. Biol. Chem. 2005) 3 64

Products for HAS2-AS1 Gene

Sources for HAS2-AS1 Gene

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