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Aliases for HAR1A Gene

Subcategory (RNA class) for HAR1A Gene

lncRNA

Quality Score for this RNA gene is

3

Aliases for HAR1A Gene

  • Highly Accelerated Region 1A (Non-Protein Coding) 2 3
  • Highly Accelerated Region 1A (Non-Protein-Coding RNA) 2 3
  • Long Intergenic Non-Protein Coding RNA 64 2 3
  • HAR1F 3 6
  • Human Accelerated Region 1, Forward 3
  • Human Accelerated Region 1 2
  • Non-Protein Coding RNA 64 2
  • NCRNA00064 3
  • LINC00064 3
  • Forward 2

External Ids for HAR1A Gene

Summaries for HAR1A Gene

GeneCards Summary for HAR1A Gene

HAR1A (Highly Accelerated Region 1A (Non-Protein Coding)) is a RNA Gene, and belongs to lncRNA RNA class.

fRNAdb sequence ontologies for HAR1A Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • ncRNA: An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

  • antisense_RNA: Antisense RNA is RNA that is transcribed from the coding, rather than the template, strand of DNA. It is therefore complementary to mRNA.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for HAR1A Gene

Genomics for HAR1A Gene

Genomic Location for HAR1A Gene

Start:
63,101,292 bp from pter
End:
63,104,386 bp from pter
Size:
3,095 bases
Orientation:
Plus strand

Genomic View for HAR1A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HAR1A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HAR1A Gene

Regulatory Elements for HAR1A Gene

Proteins for HAR1A Gene

Post-translational modifications for HAR1A Gene

No Post-translational modifications

No data available for DME Specific Peptides for HAR1A Gene

Domains for HAR1A Gene

Gene Families for HAR1A Gene

HGNC:
  • LNCRNA :Long non-coding RNAs
genes like me logo Genes that share domains with HAR1A: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for HAR1A Gene

Function for HAR1A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for HAR1A Gene

Localization for HAR1A Gene

No data available for Gene Ontology (GO) - Cellular Components for HAR1A Gene

Pathways for HAR1A Gene

SuperPathways for HAR1A Gene

No Data Available

Interacting Proteins for HAR1A Gene

Gene Ontology (GO) - Biological Process for HAR1A Gene

None

No data available for Pathways by source for HAR1A Gene

Transcripts for HAR1A Gene

mRNA/cDNA for HAR1A Gene

(4) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HAR1A Gene

Highly accelerated region 1A (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HAR1A Gene

No ASD Table

Relevant External Links for HAR1A Gene

GeneLoc Exon Structure for
HAR1A
ECgene alternative splicing isoforms for
HAR1A

Expression for HAR1A Gene

mRNA expression in normal human tissues for HAR1A Gene

mRNA differential expression in normal tissues according to GTEx for HAR1A Gene

This gene is overexpressed in Brain - Cortex (5.8), Brain - Frontal Cortex (BA9) (4.7), and Brain - Nucleus accumbens (basal ganglia) (4.1).

SOURCE GeneReport for Unigene cluster for HAR1A Gene Hs.549606

genes like me logo Genes that share expressions with HAR1A: view

Orthologs for HAR1A Gene

This gene was present in the common ancestor of chordates.

Orthologs for HAR1A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia HAR1A 37
  • 86 (a)
OneToOne
cow
(Bos Taurus)
Mammalia HAR1A 37
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia HAR1A 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm22842 37
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia HAR1A 37
  • 84 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia HAR1A 37
  • 81 (a)
OneToOne
chicken
(Gallus gallus)
Aves HAR1A 37
  • 83 (a)
OneToOne
Species with no ortholog for HAR1A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for HAR1A Gene

ENSEMBL:
Gene Tree for HAR1A (if available)
TreeFam:
Gene Tree for HAR1A (if available)

Paralogs for HAR1A Gene

No data available for Paralogs for HAR1A Gene

Variants for HAR1A Gene

Sequence variations from dbSNP and Humsavar for HAR1A Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs76803877 -- 63,104,474(+) CTTTC(C/T)GGCCC downstream-variant-500B
rs77772229 -- 63,104,653(+) CCCAC(A/G)CAATC downstream-variant-500B
rs140183532 -- 63,104,457(+) ACAGA(C/T)GGAGC downstream-variant-500B
rs142505213 -- 63,104,503(+) GACCC(C/G)TGCTC downstream-variant-500B
rs200892645 -- 63,104,613(+) CCCTG(-/C)CCCCC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for HAR1A Gene

Variant ID Type Subtype PubMed ID
nsv913073 CNV Loss 21882294
nsv9825 CNV Gain 18304495
dgv4618n71 CNV Loss 21882294
dgv4623n71 CNV Loss 21882294
nsv834028 CNV Loss 17160897
dgv4625n71 CNV Loss 21882294
nsv913160 CNV Loss 21882294
nsv913161 CNV Loss 21882294
nsv913162 CNV Loss 21882294
dgv68n68 CNV Loss 17160897
nsv913163 CNV Loss 21882294
nsv3444 CNV Insertion 18451855
esv1000562 CNV Insertion 20482838
nsv513560 CNV Insertion 21212237
esv2537683 CNV Loss 19546169

Relevant External Links for HAR1A Gene

HapMap Linkage Disequilibrium report
HAR1A

Disorders for HAR1A Gene

No disorders were found for HAR1A Gene.

No data available for UniProtKB/Swiss-Prot for HAR1A Gene

Publications for HAR1A Gene

  1. An RNA gene expressed during cortical development evolved rapidly in humans. (PMID: 16915236) Pollard K.S. … Haussler D. (Nature 2006) 2 3
  2. Rapid evolving RNA gene HAR1A and schizophrenia. (PMID: 18054202) Tolosa A. … de Frutos R. (Schizophr. Res. 2008) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for HAR1A Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate HAR1A
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for HAR1A
    • Block miRNA regulation of HAR1A using miScript Target Protectors

    Sources for HAR1A Gene

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