highly accelerated region 1A (non-protein coding) (Previous name: highly accelerated region 1A (non-protein-coding RNA) )
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Aliasesfor HAR1A gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Subcategory (RNA class): lncRNAQuality score for this RNA gene is 11 Aliases Highly Accelerated Region 1A (Non-Protein Coding) 1 2 HAR1F1 2 5 LINC000641 2 NCRNA000641 2 Highly Accelerated Region 1A (Non-Protein-Coding RNA)1
External Ids: HGNC: 33117 1 Entrez Gene: 768096 2 Ensembl: ENSG00000225978 7 OMIM: 610556 5 Export aliases for HAR1A gene to outside databases Previous GC identifers: GC20U900285 GC20P061203 GC20P058450
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Summariesfor HAR1A gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section fRNAdb sequence ontologies for HAR1A - the ORGUL cluster for this gene includes several descriptions: Human accelerated region 1F - ncRNA - An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.antisense_RNA - Antisense RNA is RNA that is transcribed from the coding, rather than the template, strand of DNA. It is therefore complementary to mRNA.
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Genomic Viewsfor HAR1A gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000020.10 NC_018931.1 NT_011333.6 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the HAR1A gene promoter: STAT5B USF1 GATA-1 SRY USF-1 FOXO1a Zic3 FOXO1 En-1 Other transcription factors Search SABiosciences Chromatin IP Primers for HAR1A Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HAR1A
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 20q13.33 Ensembl cytogenetic band: 20q13.33 HGNC cytogenetic band: 20q13.33 HAR1A Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 20 GeneLoc Exon Structure
GeneLoc location for GC20P061732: view genomic region
(about GC identifiers )
Start:
61,732,644 bp from pter
End:
61,735,738 bp from pter
Size:
3,095 bases
Orientation:
plus strand
ORGUL member locations:Legend (see complete legend)
FR0326184
n343069
RF00635
FR0407510
n339752
n376771
61732643 61734190 61735737 chr20
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Proteinsfor HAR1A gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB: --
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Protein
Domains / Familiesfor HAR1A gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section --
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Functionfor HAR1A gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAR1A
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Pathways & Interactionsfor HAR1A gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HAR1A
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Drugs & Compoundsfor HAR1A gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for HAR1A Search CenterWatch for drugs/clinical trials and news about HAR1A
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Transcriptsfor HAR1A gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section Unigene Cluster for HAR1A:
Highly accelerated region 1A (non-protein coding) Hs.549606 [show with all ESTs ] Unigene Representative Sequence: DQ860409 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000433161(lincRNA) (uc002yef.1 ) Additional cDNA sequence: BC035016.1 BC047717.1 DQ860409.1 NR_003244.1
1 DOTS entry : DT.97766495 GeneLoc Exon Structure
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Expression for HAR1A gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section Expression evidence for HAR1A:RNAdb
HAR1A expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GGTGTTTGGA
About this image Genevestigator expression for HAR1A SOURCE GeneReport for Unigene cluster: Hs.549606 SABiosciences Custom PCR Arrays for HAR1A Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for HAR1ABrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse / rat HAR1A Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAR1A QIAGEN QuantiFast Probe-based Assays in human , mouse , rat HAR1A In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAR1A
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Orthologsfor HAR1A gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
--
ENSEMBL Gene Tree for HAR1A (if available)TreeFam Gene Tree for HAR1A (if available)
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Paralogsfor HAR1A gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor HAR1A gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 20 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for HAR1A (61732644 - 61735738 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 3 variations for HAR1A 3 CNVs : 5146 31044 103028
SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor HAR1A gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
HAR1A for disorders About GeneDecksing OMIM gene information: 610556 610557 1 disease for HAR1A : About MalaCards schizophrenia Export disorders for HAR1A gene to outside databases
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Publicationsfor HAR1A gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for HAR1A gene integrated from 9 sources : (articles sorted by number of sources associating them with HAR1A) Utopia : connect your pdf to the dynamic world of online information
An RNA gene expressed during cortical development evolved rapidly in humans. (PubMed id 16915236) 1 , 3 Pollard K.S....Haussler D. (2006) Rapid evolving RNA gene HAR1A and schizophrenia. (PubMed id 18054202) 1 Tolosa A....de Frutos R. (2008) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) (PubMed id 15103394) 10 (PubMed id 18089548) 10 (PubMed id 15608161) 10
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External Searches for HAR1A gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing HAR1A gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing HAR1A gene
(According to HUGE )
About This Section --
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Specialized Databases showing HAR1A gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for HAR1A Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for HAR1A gene: Search GeneIP for patents involving HAR1A GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor HAR1A gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HAR1A Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HAR1A QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HAR1A QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat HAR1A QIAGEN QuantiFast Probe-based Assays in human , mouse , rat HAR1A Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAR1A
Search Tocris compounds for HAR1A
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAR1A
Search ThermoFisher Antibodies for HAR1A
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat HAR1A
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Aliases for HAR1A
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