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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HAPLN4 Gene

protein-coding   GIFtS: 49
GCID: GC19M019366

Hyaluronan And Proteoglycan Link Protein 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Hyaluronan And Proteoglycan Link Protein 41 2
Brain Link Protein 21 2 3
BRAL22 3
KIAA19263

External Ids:    HGNC: 313571   Entrez Gene: 4040372   Ensembl: ENSG000001876647   UniProtKB: Q86UW83   

Export aliases for HAPLN4 gene to outside databases

Previous GC identifers: GC19M019227 GC19M019229 GC19M019230 GC19M018932


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for HAPLN4 Gene: 
HAPLN4 (hyaluronan and proteoglycan link protein 4) is a protein-coding gene. Diseases associated with HAPLN4 include malignant glioma, and schizophrenia, and among its related super-pathways are FAK1 Signaling and MAPK Signaling. GO annotations related to this gene include hyaluronic acid binding. An important paralog of this gene is HAPLN1.

UniProtKB/Swiss-Prot: HPLN4_HUMAN, Q86UW8
Function: Binds to hyaluronic acid and may be involved in formation of the extracellular matrix (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011295.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HAPLN4 gene promoter:
         Egr-3   GATA-3   RREB-1   Lmo2   HNF-4alpha1   GATA-2   GATA-1   CREB   FOXC1   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHAPLN4 promoter sequence
   Search SABiosciences Chromatin IP Primers for HAPLN4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HAPLN4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.1   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13.1

HAPLN4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HAPLN4 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M019366:  view genomic region     (about GC identifiers)

Start:
19,366,450 bp from pter      End:
19,373,605 bp from pter
Size:
7,156 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HPLN4_HUMAN, Q86UW8 (See protein sequence)
Recommended Name: Hyaluronan and proteoglycan link protein 4 precursor  
Size: 402 amino acids; 42801 Da
Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)
Sequence caution: Sequence=BAB67819.1; Type=Erroneous initiation;
Secondary accessions: A5PKW5 Q96PW2

Explore the universe of human proteins at neXtProt for HAPLN4: NX_Q86UW8

Explore proteomics data for HAPLN4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q86UW8

  • HAPLN4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HAPLN4 Protein Expression
    REFSEQ proteins: NP_075378.1  
    ENSEMBL proteins: 
     ENSP00000291481  

    Human Recombinant Protein Products for HAPLN4: 
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    Novus Biologicals HAPLN4 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HAPLN4 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix IEA--

    HAPLN4 for ontologies           About GeneDecksing



    HAPLN4 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for HAPLN4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    VSET: Immunoglobulin superfamily / V-set domain containing

    5/7 InterPro protein domains (see all 7):
     IPR003598 Ig_sub2
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR000538 Link
     IPR007110 Ig-like_dom

    Graphical View of Domain Structure for InterPro Entry Q86UW8

    ProtoNet protein and cluster: Q86UW8

    3 Blocks protein domains:
    IPB000538 Link domain
    IPB003598 Immunoglobulin C-2 type
    IPB013106 Immunoglobulin V-set


    UniProtKB/Swiss-Prot: HPLN4_HUMAN, Q86UW8
    Similarity: Belongs to the HAPLN family
    Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain
    Similarity: Contains 2 Link domains


    HAPLN4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HPLN4_HUMAN, Q86UW8
    Function: Binds to hyaluronic acid and may be involved in formation of the extracellular matrix (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0005540hyaluronic acid binding IEA--
         
    HAPLN4 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for HAPLN4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HAPLN4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HAPLN4 
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    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HAPLN4
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate HAPLN4 (see all 13):
    hsa-miR-4324 hsa-miR-3934 hsa-miR-615-5p hsa-miR-196a* hsa-miR-1914* hsa-miR-589* hsa-miR-587 hsa-miR-409-5p
    SwitchGear 3'UTR luciferase reporter plasmidHAPLN4 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAPLN4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for HAPLN4 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Integrin Pathway
    Integrin Pathway0.67
    UPA-UPAR Pathway0.56
    FAK1 Signaling0.67
    Inhibition of Angiogenesis by TSP10.50
    GnRH Signaling0.56
    Transendothelial Migration of Leukocytes0.38
    2Rho Family GTPases
    Rho Family GTPases0.61
    Molecular Mechanisms of Cancer0.51
    ERK Signaling0.61
    ILK Signaling0.49
    MAPK Signaling0.58
    3PTEN Pathway
    PTEN Pathway0.56
    Phospholipase-C Pathway0.56

    5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for HAPLN4 (see all 13)
        MAPK Signaling
    Molecular Mechanisms of Cancer
    PTEN Pathway
    Transendothelial Migration of Leukocytes
    UPA-UPAR Pathway


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HAPLN4

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion IEA--

    HAPLN4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HAPLN4 (HPLN4)

    1 HMDB Compound for HAPLN4    About this table
    CompoundSynonyms CAS #PubMed Ids
    Hyaluronic acidhyaluronic acid 9004-61-9--

    Search CenterWatch for drugs/clinical trials and news about HAPLN4 / HPLN4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HAPLN4 gene: 
    NM_023002.2  

    Unigene Cluster for HAPLN4:

    Hyaluronan and proteoglycan link protein 4
    Hs.367829  [show with all ESTs]
    Unigene Representative Sequence: BC142698
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000291481(uc002nmb.3 uc002nmc.3) ENST00000592862
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HAPLN4
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate HAPLN4 (see all 13):
    hsa-miR-4324 hsa-miR-3934 hsa-miR-615-5p hsa-miR-196a* hsa-miR-1914* hsa-miR-589* hsa-miR-587 hsa-miR-409-5p
    SwitchGear 3'UTR luciferase reporter plasmidHAPLN4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HAPLN4
    Clone
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    GenScript: all cDNA clones in your preferred vector: HAPLN4 (NM_023002)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HAPLN4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAPLN4
    Sirion Biotech Customized lentivirus for stable overexpression of HAPLN4 
                         Customized lentivirus expression plasmids for stable overexpression of HAPLN4 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for HAPLN4
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAPLN4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAPLN4

    Additional mRNA sequence: 

    AB107883.1 AL389941.1 AY262756.1 BC142644.1 BC142698.1 

    3 DOTS entries:

    DT.91691895  DT.121493075  DT.407752 

    24/43 AceView cDNA sequences (see all 43):

    NM_203510 AF255923 AA907902 BE047138 AK026307 CK300169 AB107883 BM683825 
    AK097070 AB067513 NM_023002 AY262756 BX096239 AW450803 NM_001001524 AI826108 
    BI757362 N99350 BQ189795 BQ188688 BM930363 AL389941 AL389940 BM682566 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HAPLN4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACAACCAGAC
    HAPLN4 Expression
    About this image


    See HAPLN4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HAPLN4

    SOURCE GeneReport for Unigene cluster: Hs.367829

    UniProtKB/Swiss-Prot: HPLN4_HUMAN, Q86UW8
    Tissue specificity: Expressed predominantly in brain

        SABiosciences Custom PCR Arrays for HAPLN4
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAPLN4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for HAPLN4 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hapln41 , 5 hyaluronan and proteoglycan link protein 41, 5 83.96(n)1
    91.48(a)1
      8 (34.15 cM)5
    3307901  NM_177900.41  NP_808568.11 
     700835295 
    chicken
    (Gallus gallus)
    Aves LOC1008583651 hyaluronan and proteoglycan link protein 4-like 70.35(n)
    71.39(a)
      100858365  XM_003642888.1  XP_003642936.1 
    lizard
    (Anolis carolinensis)
    Reptilia HAPLN46
    Uncharacterized protein
    55(a)
    1 ↔ 1
    GL344241.1(609-14241)
    zebrafish
    (Danio rerio)
    Actinopterygii hapln41 hyaluronan and proteoglycan link protein 4 63.9(n)
    65.81(a)
      559818  NM_001044907.1  NP_001038372.1 


    ENSEMBL Gene Tree for HAPLN4 (if available)
    TreeFam Gene Tree for HAPLN4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HAPLN4 gene
    HAPLN12  HAPLN32  ACAN2  BCAN2  NCAN2  VCAN2  HAPLN22  
    9 SIMAP similar genes for HAPLN4 using alignment to 2 protein entries:     HPLN4_HUMAN (see all proteins):
    TM6SF2    HAPLN1    HAPLN3    TM6SF1    HAPLN2    BCAN
    ACAN    CSPG3 variant protein    VCAN

    HAPLN4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/167 SNPs in HAPLN4 are shown (see all 167)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1169957321,2
    C,F--19365965(+) TGGCTA/GAAGGG 1 -- int11Minor allele frequency- G:0.03EA 120
    rs1505268621,2
    --19366119(+) GAGGCA/CGAGGT 1 -- int10--------
    rs1395200031,2
    --19366174(+) CATGGA/TGAAAC 1 -- int10--------
    rs1492326411,2
    C--19366182(+) AACCCC/TGTCTC 1 -- int10--------
    rs1444400301,2
    C--19366226(+) GCAGGC/TACCTG 1 -- int10--------
    rs1908557281,2
    --19366367(+) AAAACA/CAAAAA 1 -- int10--------
    rs9883391,2
    C,F,O,A,H--19366407(+) TTATCT/AACCAA 1 -- int18Minor allele frequency- A:0.03NA NS EA WA 680
    rs1394950201,2
    --19366434(+) AATTAA/CCCACT 1 -- int10--------
    rs729990331,2
    C,F--19366632(+) CAAAAC/TTCAGA 1 -- ut311Minor allele frequency- T:0.07NA 120
    rs172160411,2
    C,F,H--19366643(+) GATAGG/ATTTCC 1 -- ut3121Minor allele frequency- A:0.18NA NS EA CSA WA 2039

    HapMap Linkage Disequilibrium report for HAPLN4 (19366450 - 19373605 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for HAPLN4:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv911304CNV Loss21882294
    nsv911306CNV Loss21882294
    nsv911305CNV Loss21882294
    nsv911303CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for HAPLN4:    About MalaCards
    malignant glioma    schizophrenia


    HAPLN4 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: HAPLN4 (1 document)

    Export disorders for HAPLN4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HAPLN4 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with HAPLN4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A hyaluronan binding link protein gene family whose members are physically linked adjacent to chondroitin sulfate proteoglycan core protein genes: the missing links. (PubMed id 12663660)1, 2, 3, 9 Spicer A.P.... Bowling R.A. Jr. (2003)
    2. Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets. (PubMed id 14550776)1, 2 Bekku Y.... Oohashi T. (2003)
    3. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)1, 2 Nagase T....Ohara O. (2001)
    4. Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associa ted with disease risk and cortical surface area. (PubMed id 20950796)1 KAohler A.K....Andreassen O.A. (2011)
    5. Reduced expression of the hyaluronan and proteoglycan link proteins in malignant gliomas. (PubMed id 19633295)1 Sim H....Viapiano M.S. (2009)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 404037 HGNC: 31357 AceView: HAPLN4andTM6SF2 Ensembl:ENSG00000187664 euGenes: HUgn404037
    ECgene: HAPLN4 H-InvDB: HAPLN4

    (According to HUGE)
    About This Section
    HUGE: KIAA1926

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HAPLN4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HAPLN4 gene:
    Search GeneIP for patents involving HAPLN4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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