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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HAPLN2 Gene

protein-coding   GIFtS: 46
GCID: GC01P156589

hyaluronan and proteoglycan link protein 2

 Explore 4 diseases affiliated with
HAPLN2 via our new
 Human Malady Compendium 
Biological research products
for HAPLN2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Hyaluronan And Proteoglycan Link Protein 21 2
BRAL11 2 3
Brain Link Protein 12 3
Brain Link Protein-12

External Ids:    HGNC: 174101   Entrez Gene: 604842   Ensembl: ENSG000001327027   UniProtKB: Q9GZV73   

Export aliases for HAPLN2 gene to outside databases

Previous GC identifers: GC01P153806 GC01P153402 GC01P154855 GC01P127946


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: HPLN2_HUMAN, Q9GZV7
Function: Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the
hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general
structural stabilization. Binds to hyaluronic acid (By similarity)

Gene Wiki entry for HAPLN2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HAPLN2 gene promoter:
         AML1a   p53   NRSF form 1   AP-4   NRSF form 2   Evi-1   YY1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHAPLN2 promoter sequence
   Search SABiosciences Chromatin IP Primers for HAPLN2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HAPLN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23.1   Ensembl cytogenetic band:  1q23.1   HGNC cytogenetic band: 1q23.1

HAPLN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HAPLN2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P156589:  view genomic region     (about GC identifiers)

Start:
156,589,086 bp from pter      End:
156,595,517 bp from pter
Size:
6,432 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: HPLN2_HUMAN, Q9GZV7 (See protein sequence)
Recommended Name: Hyaluronan and proteoglycan link protein 2 precursor  
Size: 340 amino acids; 37775 Da
Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)

Explore the universe of human proteins at neXtProt for HAPLN2: NX_Q9GZV7

HAPLN2 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_068589.1  
ENSEMBL proteins: 
 ENSP00000255039   ENSP00000388835  

Human Recombinant Protein Products: 
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OriGene Protein Over-expression Lysate: HAPLN2
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Novus Biologicals HAPLN2 Proteins
Novus Biologicals HAPLN2 Lysate
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins
Uscn Proteins for HAPLN2

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005578proteinaceous extracellular matrix IEA--


HAPLN2 for ontologies           About GeneDecksing



HAPLN2 Antibody Products: 
EMD Millipore Mono- and Polyclonal Antibodies for the study of HAPLN2
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Uscn Antibodies for HAPLN2
ThermoFisher Antibodies for HAPLN2

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Uscn ELISAs and CLIAs for HAPLN2


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HAPLN2 for domains           About GeneDecksing

5/7 InterPro domains/families (see all 7):
 IPR013783 Ig-like_fold
 IPR013106 Ig_V-set
 IPR000538 Link
 IPR007110 Ig-like_dom
 IPR016187 C-type_lectin_fold

Graphical View of Domain Structure for InterPro Entry Q9GZV7

ProtoNet protein and cluster: Q9GZV7

3 Blocks protein families:
IPB000538 Link domain
IPB003599 Immunoglobulin subtype
IPB013106 Immunoglobulin V-set


UniProtKB/Swiss-Prot: HPLN2_HUMAN, Q9GZV7
Similarity: Belongs to the HAPLN family
Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain
Similarity: Contains 2 Link domains


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

     UniProtKB/Swiss-Prot: HPLN2_HUMAN, Q9GZV7
Function: Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the
hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general
structural stabilization. Binds to hyaluronic acid (By similarity)

miRNA
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Browse MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HAPLN2
5 QIAGEN miScript miRNA Assays for microRNAs that regulate HAPLN2:
hsa-miR-569 hsa-miR-365 hsa-miR-935 hsa-miR-137 hsa-miR-155
SwitchGear 3'UTR luciferase reporter plasmidHAPLN2 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HAPLN2 (see all 7)
OriGene shRNA RFP: HAPLN2
OriGene siRNA: HAPLN2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HAPLN2

Gene Editing
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HAPLN2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: HAPLN2 (NM_021817)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAPLN2 

Cell Line
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Search LifeMap BioReagents cell lines for HAPLN2

In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAPLN2

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005540hyaluronic acid binding IEA--


HAPLN2 for ontologies           About GeneDecksing


Animal Models:
     2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Hapln2):
 nervous system  vision/eye 

HAPLN2 for phenotypes           About GeneDecksing


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways  About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1Integrin Pathway
Integrin Pathway1.00
UPA-UPAR Pathway0.51
FAK1 Signaling0.67
Transendothelial Migration of Leukocytes0.38
GnRH Signaling0.56
Inhibition of Angiogenesis by TSP10.37
2Rho Family GTPases
Rho Family GTPases1.00
MAPK Signaling0.51
ERK Signaling0.61
ILK Signaling0.45
Molecular Mechanisms of Cancer0.51
3PTEN Pathway
PTEN Pathway1.00
Phospholipase-C Pathway0.56

5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for HAPLN2 (see all 13)
    MAPK Signaling
Molecular Mechanisms of Cancer
PTEN Pathway
Transendothelial Migration of Leukocytes
UPA-UPAR Pathway


Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HAPLN2

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007155cell adhesion IEA--


HAPLN2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for HAPLN2

1 HMDB Compound for HAPLN2    About this table
CompoundSynonyms CAS #PubMed Ids
Hyaluronic acidhyaluronic acid 9004-61-9--
Search CenterWatch for drugs/clinical trials and news about HAPLN2 / HPLN2 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for HAPLN2 gene: 
NM_021817.2  

Unigene Cluster for HAPLN2:

Hyaluronan and proteoglycan link protein 2
Hs.410719  [show with all ESTs]
Unigene Representative Sequence: AK094121
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000255039(uc001fpn.1) ENST00000487988 ENST00000456112(uc010phq.1)
ENST00000477201 ENST00000482204 ENST00000494218

miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HAPLN2
5 QIAGEN miScript miRNA Assays for microRNAs that regulate HAPLN2:
hsa-miR-569 hsa-miR-365 hsa-miR-935 hsa-miR-137 hsa-miR-155
SwitchGear 3'UTR luciferase reporter plasmidHAPLN2 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HAPLN2 (see all 7)
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OriGene siRNA: HAPLN2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HAPLN2
Clone
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OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HAPLN2
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SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HAPLN2
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAPLN2
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAPLN2

Additional cDNA sequence: 

AB049054.1 AK090712.1 AK094121.1 AK293797.1 AK294131.1 AK308805.1 AK308980.1 AK310758.1 
BC029864.1 

12 DOTS entries:

DT.40250642  DT.427521  DT.97817261  DT.121348924  DT.99998042  DT.121348922  DT.75148902  DT.95162717 
DT.100020273  DT.121348907  DT.121348908  DT.121348914 

24/47 AceView cDNA sequences (see all 47):

NM_021817 BM548424 AI459802 CF457207 BI489912 BC029864 AK090712 BM921096 
H43809 BI821339 AI460086 BI756421 CB153631 BI824586 BV206517 BM709346 
BI821582 AI973128 AW015789 BF594173 R88039 BM543514 CB054443 BU732720 

GeneLoc Exon Structure

5/15 Alternative Splicing Database (ASD) splice patterns (SP) for HAPLN2 (see all 15)    About this scheme

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h · 1i ^ 2a · 2b · 2c · 2d · 2e · 2f · 2g · 2h ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c · 4d ^ 5a ·
SP1:                                                        -     -                                               -     -     -                                 
SP2:                                                        -     -                                               -     -     -                                 
SP3:                                                                                                              -     -     -                                 
SP4:                                                        -     -     -     -     -     -     -                 -     -     -                                 
SP5:                                                        -     -                                               -     -     -     -     -     -     -         

ExUns: 5b · 5c · 5d · 5e · 5f ^ 6a · 6b ^ 7 ^ 8
SP1:                                                      
SP2:                                -                     
SP3:                                                      
SP4:                                                      
SP5:                                                      


ECgene alternative splicing isoforms for HAPLN2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

HAPLN2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)

About this image
See HAPLN2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HAPLN2

SOURCE GeneReport for Unigene cluster: Hs.410719

UniProtKB/Swiss-Prot: HPLN2_HUMAN, Q9GZV7
Tissue specificity: Expressed only in adult brain

    SABiosciences Custom PCR Arrays for HAPLN2
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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAPLN2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAPLN2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for HAPLN2 gene from 2/8 species (see all 8)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
chicken
(Gallus gallus)
Aves HAPLN21 hyaluronan and proteoglycan link protein 2 68.96(n)
66.87(a)
  425975  XM_423654.3  XP_423654.3 
zebrafish
(Danio rerio)
Actinopterygii hapln21 hyaluronan and proteoglycan link protein 2 59.6(n)
58.61(a)
  558291  NM_001082816.2  NP_001076285.2 


ENSEMBL Gene Tree for HAPLN2 (if available)
TreeFam Gene Tree for HAPLN2 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for HAPLN2 gene
HAPLN12  HAPLN42  HAPLN32  ACAN2  BCAN2  NCAN2  VCAN2  
8 SIMAP similar genes for HAPLN2 using alignment to 3 protein entries:     HPLN2_HUMAN (see all proteins):
HAPLN3    HAPLN4    BCAN    CSPG3 variant protein    NCAN    HAPLN1
VCAN    ACAN

HAPLN2 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/159 NCBI SNPs in HAPLN2 are shown (see all 159    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs751656391,2
C--156587143(+) TGGTTC/TTTTTT 1 -- us2k10--------
rs46381221,2
C,A,--156587232(+) CCTCCC/TGGGTT 1 -- us2k16Minor allele frequency- T:0.00NA WA CSA 10
rs1453374781,2
--156587404(+) CCAAAA/GTGTTG 1 -- us2k10--------
rs567713131,2
C--156587443(+) TTTTTT/-AACTC 1 -- us2k11Minor allele frequency- -:0.00NA 2
rs1885776111,2
--156587635(+) AACAAC/TTGGGC 1 -- us2k10--------
rs1492275621,2
--156587696(+) CCTGTA/GTACAA 1 -- us2k10--------
rs1811449891,2
--156587864(+) TGGGCA/GGATTG 1 -- us2k10--------
rs120779551,2
C,--156587951(+) ttggcG/Atggtg 1 -- us2k14Minor allele frequency- A:0.06NA WA 124
rs75270801,2
C,F,A,--156588015(+) TTGAAC/GCCGGG 1 -- us2k16Minor allele frequency- G:0.30NA WA CSA EA 364
rs572192641,2
C--156588098(+) AAAAA-/AAAAAA
        
GTTAA
1 -- us2k11Minor allele frequency- AAAAAA:0.00NA 2

HapMap Linkage Disequilibrium report for HAPLN2 (156589086 - 156595517 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for HAPLN2: --

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HAPLN2
DNA2.0 Custom Variant and Variant Library Synthesis for HAPLN2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

HAPLN2 for disorders           About GeneDecksing

4 diseases for HAPLN2:    About MalaCards
malignant glioma    rabies    schizophrenia    neuronitis

Human Genome Epidemiology (HuGE) Navigator: HAPLN2 (1 document)

Export disorders for HAPLN2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for HAPLN2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with HAPLN2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The brain link protein-1 (BRAL1): cDNA cloning, genomic structure, and characterization as a novel link protein expressed in adult brain. (PubMed id 11027579)1, 2, 3, 9 Hirakawa S....Ninomiya Y. (2000)
  2. Human BRAL1 and BCAN genes that belong to the link-mo dule superfamily are tandemly arranged on chromosome 1q21-23. (PubMed id 11873941)1, 3, 9 Nomoto H....Ninomiya Y. (2002)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. A hyaluronan binding link protein gene family whose members are physically linked adjacent to chondroitin sulfate proteoglycan core protein genes: the missing links. (PubMed id 12663660)1, 9 Spicer A.P.... Bowling R.A. Jr. (2003)
  5. Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associa ted with disease risk and cortical surface area. (PubMed id 20950796)1 KAohler A.K....Andreassen O.A. (2011)
  6. Reduced expression of the hyaluronan and proteoglycan link proteins in malignant gliomas. (PubMed id 19633295)1 Sim H....Viapiano M.S. (2009)
  7. Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis. (PubMed id 19034380)1 Martins-de-Souza D....Dias-Neto E. (2008)
  8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  10. Bral1, a brain-specific link protein, colocalizing with the versican V2 isoform at the nodes of Ranvier in developing and adult mouse central nervous systems. (PubMed id 11817897)1 Oohashi T....Ninomiya Y. (2002)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 60484 HGNC: 17410 AceView: HAPLN2 Ensembl:ENSG00000132702 euGenes: HUgn60484
ECgene: HAPLN2 H-InvDB: HAPLN2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for HAPLN2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
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IP news from LifeMap Sciences, Inc.)
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Patent Information for HAPLN2 gene:
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