Aliases for HAO2 Gene
External Ids for HAO2 Gene
Previous GeneCards Identifiers for HAO2 Gene
This gene is one of three related genes that have 2-hydroxyacid oxidase activity. The encoded protein localizes to the peroxisome has the highest activity toward the substrate 2-hydroxypalmitate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
GeneCards Summary for HAO2 Gene
HAO2 (Hydroxyacid Oxidase 2 (Long Chain)) is a Protein Coding gene. Diseases associated with HAO2 include primary hyperoxaluria. Among its related pathways are Metabolism and Peroxisome. GO annotations related to this gene include receptor binding and (S)-2-hydroxy-acid oxidase activity. An important paralog of this gene is HAO1.
UniProtKB/Swiss-Prot for HAO2 Gene
Catalyzes the oxidation of L-alpha-hydroxy acids as well as, more slowly, that of L-alpha-amino acids