HAO1 Gene
protein-coding GIFtS: 60
GCID: GC20M007863
|
|
hydroxyacid oxidase (glycolate oxidase) 1
(Previous symbol: GOX1)
| |
Aliases
for HAO1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Hydroxyacid Oxidase (Glycolate Oxidase) 11 2 | | HAOX12 3 | | GOX11 2 3 5 | | (S)-2-Hydroxy-Acid Oxidase2 | | GOX1 2 3 | | Hydroxyacid Oxidase 12 | | Glycolate Oxidase2 3 | | EC 1.1.3.153 |
Export aliases for HAO1 gene to outside databasesPrevious GC identifers: GC20M007851 GC20M007858 GC20M007811 |
Summaries
for HAO1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HAO1:
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein aminoacid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is theperoxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is mostactive on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcriptdetected at high levels in pancreas may represent an alternatively spliced form or the use of a multiplenear-consensus upstream polyadenylation site. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: HAOX1_HUMAN, Q9UJM8Function: Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate
|
Genomic Views
for HAO1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HAO1 gene promoter:
GR SRF (504 AA) GR-beta C/EBPalpha PPAR-alpha POU2F1 POU2F1b POU2F1a POU2F1c GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for HAO1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HAO1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p12 Ensembl cytogenetic band: 20p12.3 HGNC cytogenetic band: 20p12HAO1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M007863: view genomic region
(about GC identifiers)
Start:
|
7,863,628 bp from pter |
End:
|
7,921,121 bp from pter |
Size:
|
57,494 bases |
Orientation:
|
minus strand |
|
Proteins
for HAO1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HAOX1_HUMAN, Q9UJM8 (See
protein sequence)Recommended Name: Hydroxyacid oxidase 1 Size: 370 amino acids; 40924 Da
Cofactor: FMN
Subcellular location: Peroxisome
5 PDB 3D structures from  and Proteopedia  for HAO1:2NZL (3D)
2RDT (3D)
2RDU (3D)
2RDW (3D)
2W0U (3D)
Secondary accessions: Q14CQ0 Q9UPZ0 Q9Y3I7Explore the universe of human proteins at neXtProt for HAO1: NX_Q9UJM8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UJM8
HAO1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060015.1
ENSEMBL proteins: ENSP00000368066 Reactome Protein details: Q9UJM8
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
HAO1 for ontologies About GeneDecksing
HAO1 Antibody Products:
Assay Products for HAO1: |
Protein
Domains /
Families
for HAO1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HAO1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UJM8ProtoNet protein and cluster: Q9UJM8 1 Blocks protein family: IPB000262 FMN-dependent alpha-hydroxy acid dehydrogenase
UniProtKB/Swiss-Prot: HAOX1_HUMAN, Q9UJM8Similarity: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase familySimilarity: Contains 1 FMN hydroxy acid dehydrogenase domain |
Function
for HAO1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: HAOX1_HUMAN, Q9UJM8Function: Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoateCatalytic activity: (S)-2-hydroxy acid + O(2) = 2-oxo acid + H(2)O(2)Biophysicochemical properties: Kinetic parameters: KM=141 uM for glycolate; KM=40 uM for 2-hydroxy octanoate; KM=2200uM for glyoxylate; Genatlas biochemistry entry for HAO1:hydroxyacid oxidase 1,glycolate oxidase
Enzyme Number (IUBMB): EC 1.1.3.151
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HAO1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HAO1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HAO1 (NM_017545) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HAO1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAO1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAO1 |
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
HAO1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for HAO1:
|
Pathways & Interactions
for HAO1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Metabolism | | | 2 | Metabolism of amino acids and derivatives | | | 3 | Peroxisome | | | 4 | Glyoxylate and dicarboxylate metabolism | | | 5 | glycine biosynthesis III | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for HAO1
3 
Kegg Pathways (Kegg details for HAO1):
UniProtKB/Swiss-Prot: HAOX1_HUMAN, Q9UJM8Pathway: Organic acid metabolism; glycolate degradation; 3-phospho-D-glycerate from glycolate: step 1/4
HAO1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HAO1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/33 Interacting proteins for HAO1 (Q9UJM83 ENSP000003680664) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
HAO1 for ontologies About GeneDecksing
|
Drugs & Compounds
for HAO1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
HAO1 for compounds About GeneDecksing
 Browse Tocris compounds for HAO1
5 HMDB Compounds for HAO1 About this table
10 DrugBank Compounds for HAO1 About this table
10/52 Novoseek chemical compound relationships for HAO1 gene (see all 52) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| glucose |
82.3 |
475 |
17365439 (5), 16870421 (3), 19505077 (3), 19269439 (3) (see all 99) |
| nafion |
82.2 |
9 |
16275055 (1), 15967398 (1), 19071561 (1), 16219381 (1) (see all 7) |
| agcl |
78.1 |
1 |
15649080 (1) |
| fadh2 |
77.4 |
8 |
15461503 (2), 12622383 (1), 15970532 (1), 15649080 (1) |
| poly(dimethyl diallyl ammonium chloride) |
77.1 |
7 |
18180205 (2), 16430853 (1), 16207046 (1), 17314038 (1) |
| poly(1-vinylimidazole) |
75.5 |
2 |
14516076 (1), 15794489 (1) |
| ferrocenemethanol |
73.6 |
1 |
16471810 (1) |
| platinum |
71.1 |
20 |
9491756 (1), 19112013 (1), 20388977 (1), 15284922 (1) (see all 13) |
| ethylene glycol diglycidyl ether |
70.9 |
2 |
7733469 (1) |
| ferrocene |
70 |
19 |
19505077 (2), 8797376 (2), 12298004 (2), 11411531 (2) (see all 10) |
Search CenterWatch for drugs/clinical trials and news about HAO1 / HAOX1
|
Transcripts
for HAO1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HAO1 gene: NM_017545.2 Unigene Cluster for HAO1: Hydroxyacid oxidase (glycolate oxidase) 1 Hs.193640 [show with all ESTs]Unigene Representative Sequence: AL1217391 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000378789(uc002wmw.1 uc010gbu.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HAO1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HAO1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HAO1 (NM_017545) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HAO1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAO1 |
Additional cDNA sequence: AB024079.1 AF231916.1 AF244134.1 AK289423.1 AK308963.1 AK313839.1 AL121739.1 BC113665.1 BC113667.1 2 DOTS entries: DT.105299 DT.99965022 24/28 AceView cDNA sequences (see all 28): BG656034 AB024079 C20914 CB161531 AL121739 NM_017545 AI913732 AF244134 H69642 AW772047 AV647445 AV682372 BG568066 AL449681 H70488 AF231916 CB163751 AV646933 BX094967 BG656337 T72614 T97637 T97636 T74667
GeneLoc Exon Structure
|
Expression
for HAO1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HAO1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTTTAAAAC
About this image
See HAO1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HAO1
SOURCE GeneReport for Unigene cluster: Hs.193640
UniProtKB/Swiss-Prot: HAOX1_HUMAN, Q9UJM8Tissue specificity: Liver
SABiosciences Custom PCR Arrays for HAO1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HAO1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HAO1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAO1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAO1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAO1 |
Orthologs
for HAO1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for HAO1 gene from 10/32 species (see all 32) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Hao11 , 5 |
hydroxyacid oxidase 1, liver1, 5 |
87.12(n)1
89.46(a)1 |
|
2 (65.65 cM)5
151121 NM_010403.21 NP_034533.11
1344973615 |
chicken
(Gallus gallus) |
Aves |
HAO11 |
hydroxyacid oxidase (glycolate oxidase) 1 |
72.16(n)
74.73(a) |
|
416728 NM_001199442.1 NP_001186371.1 |
lizard
(Anolis carolinensis) |
Reptilia |
HAO16 |
-- |
76(a) |
1 ↔ 1 |
1(135884049-135909556) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.35342 |
Xenopus laevis transcribed sequence with weak similarity more |
73.14(n) |
|
BJ036588.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.21322 |
Danio rerio cDNA clone IMAGE5914839, partial cds |
72.95(n) |
|
BC055638.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG180033 |
glycolate oxidase |
48(a) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
F41E6.51 , 3 |
glycolate oxidase3
Protein F41E6.51 |
46(a)3
51.81(n)1
46.86(a)1 |
|
V(8606190-8607675)3
1792411 NM_001129469.11 NP_001122941.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT4G183601 |
(S)-2-hydroxy-acid oxidase |
56(n)
58(a) |
|
827563 NM_117946.2 NP_193570.1 |
rice
(Oryza sativa) |
Liliopsida |
Os04g06235001 |
hypothetical protein |
54.82(n)
55.87(a) |
|
4337048 NM_001060460.1 NP_001053925.1 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
lldD6 |
L-lactate dehydrogenase, FMN-linked |
30(a) |
possible ortholog |
Chromosome(3777850-3779040) |
ENSEMBL Gene Tree for HAO1 (if available)
TreeFam Gene Tree for HAO1 (if available) |
Paralogs
for HAO1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HAO1 gene
- HAO22
1 SIMAP similar gene for HAO1 using alignment to 3 protein entries: HAOX1_HUMAN (see all proteins):HAO2
HAO1 for paralogs About GeneDecksing
|
Genomic Variants
for HAO1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HAO1 (7863628 - 7921121 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HAO1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HAO1 |
|
Disorders
/ Diseases
for HAO1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HAO1 for disorders About GeneDecksing
OMIM gene information: 605023
OMIM disorders: --
10  diseases for HAO1: About MalaCardsprimary hyperoxaluria nephrolithiasis adrenoleukodystrophy hepatitis c
thrombosis hepatitis pneumonia tuberculosis
leukemia mycobacterium tuberculosis
1 Novoseek disease relationship for HAO1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| hypoglycemia |
0 |
1 |
17365439 (1) |
Human Genome Epidemiology (HuGE) Navigator: HAO1 (1 document)
Export disorders for HAO1 gene to outside databases
|
Publications
for HAO1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HAO1 gene, integrated from 9 sources (see all 224):
(articles sorted by number of sources associating them with HAO1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases. (PubMed id 10777549)1, 2, 9 Jones J.M.... Gould S.J. (2000)
- Structure of human glycolate oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole. (PubMed id 20054120)1, 2 Bourhis J.M....Lindqvist Y. (2009)
- Active site and loop 4 movements within human glycolate oxidase: implications for substrate specificity and drug design. (PubMed id 18215067)1, 2 Murray M.S....Lowther W.T. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Identification and expression of a cDNA for human glycolate oxidase. (PubMed id 10978532)1, 2 Williams E.L.... Rumsby G. (2000)
- Molecular cloning of mouse glycolate oxidase. High evolutionary conservation and presence of an iron-responsive element-like sequence in the mRNA. (PubMed id 9891009)1, 3 Kohler S.A....Kuhn L.C. (1999)
- Stabilization of an intermediate in the oxidative half -reaction of human liver glycolate oxidase. (PubMed id 21141873)1 Pennati A. and Gadda G. (2011)
- Genome-wide association study of childhood acute lymp hoblastic leukemia in Korea. (PubMed id 20189245)1 Han S....Kang D. (2010)
- Purification and characterization of recombinant human liver glycolate oxidase. (PubMed id 17669354)1 Vignaud C....Lederer F. (2007)
|
External Searches for HAO1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HAO1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HAO1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HAO1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HAO1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HAO1 gene:
Search GeneIP for patents involving HAO1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HAO1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for HAO1 | | OriGene shRNA RFP for HAO1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HAO1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HAO1 | | | OriGene Protein Over-expression Lysate for HAO1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HAO1 | | OriGene 3'-UTR Clone for HAO1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HAO1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HAO1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for HAO1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HAO1 | | OriGene Custom Protein Services for HAO1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HAO1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HAO1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HAO1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HAO1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAO1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAO1 |
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| | | | Search Tocris compounds for HAO1 |
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 | | | HAO1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAO1 |
|  |  |  | | | | Search ThermoFisher Antibodies for HAO1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAO1 |
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