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Aliases for HAND2-AS1 Gene

Subcategory (RNA class) for HAND2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for HAND2-AS1 Gene

  • HAND2 Antisense RNA 1 (Head To Head) 2 3 5
  • Differentially Expressed In Neuroblastoma 2 3
  • Neuroblastoma Transcript 301 2 3
  • NBLA00301 3
  • DEIN 3
  • UPH 3

External Ids for HAND2-AS1 Gene

Previous GeneCards Identifiers for HAND2-AS1 Gene

  • GC04P174448

Summaries for HAND2-AS1 Gene

GeneCards Summary for HAND2-AS1 Gene

HAND2-AS1 (HAND2 Antisense RNA 1 (Head To Head)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with HAND2-AS1 include Neuroblastoma.

Additional gene information for HAND2-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HAND2-AS1 Gene

Genomics for HAND2-AS1 Gene

Regulatory Elements for HAND2-AS1 Gene

Enhancers for HAND2-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04H173520 1.8 FANTOM5 Ensembl ENCODE dbSUPER 9.9 -0.1 -83 12 TBP ATF1 TCF12 RCOR1 ATF7 CREM SP3 SMAD5 ZBTB2 ZEB2 HAND2-AS1 HAND2 LOC101928409
GH04H173414 1.6 FANTOM5 Ensembl ENCODE 10.2 -111.1 -111070 2 HDGF PKNOX1 ARNT YBX1 ZNF2 TCF12 ZNF207 ZNF143 ATF7 MCM3 CEP44 ENSG00000261646 HMGB2 HAND2-AS1 SAP30 RPL5P11 LOC101928383
GH04H174120 1.2 ENCODE dbSUPER 10.1 +593.4 593395 0 ATF1 ARNT ZSCAN4 ZNF2 RAD21 EGR1 ZNF366 ZNF143 RCOR1 CREM CEP44 HMGB2 ENSG00000261646 HAND2-AS1 GC04P174110 ENSG00000250957
GH04H173536 0.8 ENCODE dbSUPER 10.1 +9.8 9755 0 CTCF POLR2A IKZF1 EZH2 HAND2-AS1 HAND2 ENSG00000261672
GH04H173447 1 Ensembl ENCODE 6.7 -78.3 -78335 1 HDAC1 PKNOX1 TAL1 FEZF1 BATF POLR2A GATA2 NCOR1 ATF7 RCOR1 HAND2-AS1 RNU6-1096P ENSG00000261646
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HAND2-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Location for HAND2-AS1 Gene

Chromosome:
4
Start:
173,527,270 bp from pter
End:
173,591,324 bp from pter
Size:
64,055 bases
Orientation:
Plus strand

Genomic View for HAND2-AS1 Gene

Genes around HAND2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HAND2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HAND2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HAND2-AS1 Gene

Proteins for HAND2-AS1 Gene

Post-translational modifications for HAND2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HAND2-AS1 Gene

Domains & Families for HAND2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HAND2-AS1 Gene

Function for HAND2-AS1 Gene

Phenotypes From GWAS Catalog for HAND2-AS1 Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for HAND2-AS1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HAND2-AS1 Gene

Localization for HAND2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HAND2-AS1 Gene

Pathways & Interactions for HAND2-AS1 Gene

SuperPathways for HAND2-AS1 Gene

No Data Available

Interacting Proteins for HAND2-AS1 Gene

Gene Ontology (GO) - Biological Process for HAND2-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HAND2-AS1 Gene

Drugs & Compounds for HAND2-AS1 Gene

No Compound Related Data Available

Transcripts for HAND2-AS1 Gene

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for HAND2-AS1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for HAND2-AS1 Gene

No ASD Table

Relevant External Links for HAND2-AS1 Gene

GeneLoc Exon Structure for
HAND2-AS1
ECgene alternative splicing isoforms for
HAND2-AS1

Expression for HAND2-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HAND2-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for HAND2-AS1 Gene

This gene is overexpressed in Colon - Sigmoid (x9.3) and Uterus (x4.7).
genes like me logo Genes that share expression patterns with HAND2-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HAND2-AS1 Gene

Orthologs for HAND2-AS1 Gene

Evolution for HAND2-AS1 Gene

ENSEMBL:
Gene Tree for HAND2-AS1 (if available)
TreeFam:
Gene Tree for HAND2-AS1 (if available)

No data available for Orthologs for HAND2-AS1 Gene

Paralogs for HAND2-AS1 Gene

No data available for Paralogs for HAND2-AS1 Gene

Variants for HAND2-AS1 Gene

Sequence variations from dbSNP and Humsavar for HAND2-AS1 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs483353128 Likely pathogenic 173,528,900(-) GTACC(A/C)GCCGA intron-variant, upstream-variant-2KB, reference, synonymous-codon
rs1000057185 -- 173,527,051(+) GAATG(C/T)TTTTC upstream-variant-2KB, utr-variant-3-prime
rs1000104805 -- 173,530,455(+) CAGTC(A/G)GAGGA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1000156515 -- 173,569,089(+) AAGCG(A/G)TTCTC intron-variant
rs1000197403 -- 173,529,600(+) ACGGC(A/C)CGCGC intron-variant, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for HAND2-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv518998 CNV loss 19592680
nsv522261 CNV loss 19592680

Relevant External Links for HAND2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HAND2-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HAND2-AS1 Gene

Disorders for HAND2-AS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for HAND2-AS1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
neuroblastoma
  • neuroblastoma 1
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for HAND2-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HAND2-AS1
genes like me logo Genes that share disorders with HAND2-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HAND2-AS1 Gene

Publications for HAND2-AS1 Gene

  1. Recurrently deregulated lncRNAs in hepatocellular carcinoma. (PMID: 28194035) Yang Y … Lu ZJ (Nature communications 2017) 2 3 60
  2. Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma. (PMID: 19348682) Voth H … Fischer M (BMC molecular biology 2009) 2 3 60
  3. Identification of DEIN, a novel gene with high expression levels in stage IVS neuroblastoma. (PMID: 18171985) Voth H … Fischer M (Molecular cancer research : MCR 2007) 2 3 60
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 60

Products for HAND2-AS1 Gene

Sources for HAND2-AS1 Gene

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