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Aliases for HAND2-AS1 Gene

Subcategory (RNA class) for HAND2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for HAND2-AS1 Gene

  • HAND2 Antisense RNA 1 (Head To Head) 2 3 5
  • Differentially Expressed In Neuroblastoma 2 3
  • Neuroblastoma Transcript 301 2 3
  • NBLA00301 3
  • DEIN 3
  • UPH 3

External Ids for HAND2-AS1 Gene

Previous GeneCards Identifiers for HAND2-AS1 Gene

  • GC04P174448

Summaries for HAND2-AS1 Gene

GeneCards Summary for HAND2-AS1 Gene

HAND2-AS1 (HAND2 Antisense RNA 1 (Head To Head)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with HAND2-AS1 include Neuroblastoma.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HAND2-AS1 Gene

Genomics for HAND2-AS1 Gene

Regulatory Elements for HAND2-AS1 Gene

Enhancers for HAND2-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F173520 1.5 FANTOM5 Ensembl ENCODE 10 -0.1 -83 12.5 TBP ATF1 CBX3 SIN3A RAD21 SCRT2 CREM SP3 ZBTB2 REST HAND2-AS1 HAND2 LOC101928409
GH04F173369 1.1 ENCODE 12.3 -156.2 -156166 4.2 HDGF PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 FBXO8 CEP44 HMGB2 LOC105377538 HAND2 SCRG1 HAND2-AS1 LOC105377540 LOC101928383
GH04F173489 1 Ensembl ENCODE 11.1 -36.8 -36800 2.7 SAP130 JUN BHLHE40 CEBPB ZNF384 CEBPG ZNF644 JUND ATF3 SCRT2 RNU6-1096P HAND2 HAND2-AS1 SCRG1 LOC101928409
GH04F174382 0.9 Ensembl ENCODE 11.6 +856.3 856316 1.6 ZNF740 NR3C1 RELA MEF2D IRF9 ID3 ILK MGA HAND2 HAND2-AS1 ENSG00000251216 HPGD CEP44 ENSG00000249875 MIR4276
GH04F173547 0.7 Ensembl 12.4 +20.7 20731 0.8 CBX3 RNF2 MAFG DPF2 ZNF316 ATF3 HDAC2 TRIM24 NFE2 MAFK HAND2-AS1 RNU6-1096P HAND2 ENSG00000261672
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HAND2-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for HAND2-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001254532 930 5201 TBP ATF1 SUZ12 SIN3A POLR2A SCRT2 ZSCAN29 TCF7L2 ZBTB20 EZH2

Genomic Location for HAND2-AS1 Gene

Chromosome:
4
Start:
173,527,270 bp from pter
End:
173,591,324 bp from pter
Size:
64,055 bases
Orientation:
Plus strand

Genomic View for HAND2-AS1 Gene

Genes around HAND2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HAND2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HAND2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HAND2-AS1 Gene

Proteins for HAND2-AS1 Gene

Post-translational modifications for HAND2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HAND2-AS1 Gene

Domains & Families for HAND2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HAND2-AS1 Gene

Function for HAND2-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HAND2-AS1 Gene

Localization for HAND2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HAND2-AS1 Gene

Pathways & Interactions for HAND2-AS1 Gene

SuperPathways for HAND2-AS1 Gene

No Data Available

Interacting Proteins for HAND2-AS1 Gene

Gene Ontology (GO) - Biological Process for HAND2-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HAND2-AS1 Gene

Transcripts for HAND2-AS1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for HAND2-AS1 Gene

No ASD Table

Relevant External Links for HAND2-AS1 Gene

GeneLoc Exon Structure for
HAND2-AS1
ECgene alternative splicing isoforms for
HAND2-AS1

Expression for HAND2-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HAND2-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for HAND2-AS1 Gene

This gene is overexpressed in Colon - Sigmoid (x9.3) and Uterus (x4.7).
genes like me logo Genes that share expression patterns with HAND2-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for HAND2-AS1 Gene

Orthologs for HAND2-AS1 Gene

Evolution for HAND2-AS1 Gene

ENSEMBL:
Gene Tree for HAND2-AS1 (if available)
TreeFam:
Gene Tree for HAND2-AS1 (if available)

No data available for Orthologs for HAND2-AS1 Gene

Paralogs for HAND2-AS1 Gene

No data available for Paralogs for HAND2-AS1 Gene

Variants for HAND2-AS1 Gene

Sequence variations from dbSNP and Humsavar for HAND2-AS1 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs483353128 Likely pathogenic 173,528,900(-) GTACC(A/C)GCCGA intron-variant, upstream-variant-2KB, reference, synonymous-codon
rs10018007 -- 173,574,338(+) TATGG(A/C)GCAAC intron-variant
rs10019224 -- 173,534,758(+) CACCC(C/T)CCTCC intron-variant
rs10023096 -- 173,537,426(+) CCCCC(A/G)ACTCC intron-variant, nc-transcript-variant
rs10024568 -- 173,576,664(+) TGGGT(C/T)TGATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HAND2-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv518998 CNV loss 19592680
nsv522261 CNV loss 19592680

Relevant External Links for HAND2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HAND2-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HAND2-AS1 Gene

Disorders for HAND2-AS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for HAND2-AS1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
neuroblastoma
  • neuroblastoma 1
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for HAND2-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HAND2-AS1
genes like me logo Genes that share disorders with HAND2-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HAND2-AS1 Gene

Publications for HAND2-AS1 Gene

  1. Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma. (PMID: 19348682) Voth H. … Fischer M. (BMC Mol. Biol. 2009) 2 3 64
  2. Identification of DEIN, a novel gene with high expression levels in stage IVS neuroblastoma. (PMID: 18171985) Voth H. … Fischer M. (Mol. Cancer Res. 2007) 2 3 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  5. Expression profiling and characterization of 4200 genes cloned from primary neuroblastomas: identification of 305 genes differentially expressed between favorable and unfavorable subsets. (PMID: 12934113) Ohira M. … Nakagawara A. (Oncogene 2003) 3 64

Products for HAND2-AS1 Gene

Sources for HAND2-AS1 Gene

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