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HAND1 Gene

protein-coding GIFtS: 56

GC05M153834

heart and neural crest derivatives expressed 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
EHAND ^³
Hxt ^¹, ²
Thing1 ^¹, ²
bHLHa27 ^¹, ²
eHAND ^³
eHand ^¹, ²

Descriptions
Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1 ^³
basic helix-loop-helix transcription factor HAND1 ^²
heart and neural crest derivatives expressed 1 ^²

External Ids
HGNC: 4807¹
Entrez Gene: 9421²
UniProtKB: O96004³
Ensembl: ENSG00000113196⁷

Search outside databases for aliases for HAND1 gene

Previous GC identifers: GC05M153925 GC05M154450 GC05M153883

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for HAND1:

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription

factors. This gene product is one of two closely related family members, the HAND proteins, which

are asymmetrically expressed in the developing ventricular chambers and play an essential role in

cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the

right ventricle and aortic arch arteries, implicating them as mediators of congenital heart

disease. In addition, it has been suggested that this transcription factor may be required for

early trophoblast differentiation. [provided by RefSeq]

UniProtKB/Swiss-Prot: HAND1_HUMAN, O96004

Function: Plays an essential role in early trophoblast differentiation and in cardiac

morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes.

Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity)

Gene Wiki entry for HAND1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the HAND1 gene

Entrez Gene cytogenetic band: 5q33 Ensembl cytogenetic band: 5q33.2 HGNC cytogenetic band: 5q33

HAND1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M153834: (about GC identifiers)

Start:	153,834,725 bp from pter
End:	153,838,017 bp from pter
Size:	3,293 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000005.8 NT_029289.10

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: HAND1_HUMAN, O96004 (See protein sequence)

Recommended Name: Heart- and neural crest derivatives-expressed protein 1

Size: 215 amino acids; 23627 Da

Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Forms homodimers

and heterodimers with TCF3 gene products E12 and E47, HAND2 and HEY1, HEY2 and HEYL (hairy-related

transcription factors) (By similarity)

Subcellular location: Nucleus (By similarity)

REFSEQ proteins: NP_004812.1

ENSEMBL proteins:

ENSP00000231121

Human Recombinant Proteins

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	Recombinant Proteins from Abcam (HAND1)
	Human Recombinant Proteins from Abnova (HAND1)

OriGene Purified Recombinant Human Protein: HAND1

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

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Antibodies for HAND1:

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	Sigma-Aldrich Antibodies for HAND1
	R&D Systems Antibodies for HAND1
	Antibodies from Abcam (HAND1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (HAND1)
	Search Novus for antibodies for HAND1

Assays for HAND1:

	Browse Invitrogen for biochemical assays
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	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry O96004

ProtoNet protein and cluster: O96004

1 Blocks protein family: IPB001092 Basic helix-loop-helix dimerization domain bHLH

UniProtKB/Swiss-Prot: HAND1_HUMAN, O96004

Similarity: Contains 1 basic helix-loop-helix (bHLH) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HAND1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (HAND1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004821

Applied Biosystems Silencer® siRNAs for HAND1

Sigma-Aldrich siRNA for HAND1

Sigma-Aldrich shRNA for HAND1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004821
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004821
untagged cDNA clone in CMV expression vector: NM_004821

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004821

UniProtKB/Swiss-Prot: HAND1_HUMAN, O96004

Function: Plays an essential role in early trophoblast differentiation and in cardiac

morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes.

Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity)

Genatlas biochemistry entry for HAND1:

heart and neural crest derivatives expressed 1,murine eHAND gene homolog,expressed in

cytotrophoblastic cells,in prenatal and adult heart,required for trophoblast giant cell

differentiation,involved in cardiac looping,ventricular maturation and conotruncal development

9 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Hand1):

	embryogenesis	growth/size	homeostasis/metabolism	lethality-postnatal
lethality-prenatal/perinatal	muscle	nervous system	normal

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	TAS	9931445
GO:0008134	transcription factor binding	IEA	--
GO:0016564	transcription repressor activity	IEA	--
GO:0042803	protein homodimerization activity	IEA	--
GO:0046982	protein heterodimerization activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for HAND1 (Your Favorite Gene powered by Ingenuity)

Cardiac Hypertrophy Signaling

GeneDecks HAND1 for the pathways selected above

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5/20 Interacting proteins for HAND1 (ENSP00000231121³) via UniProtKB, MINT, and/or STRING (see all 20 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HAND2	ENSP00000352565³	STRING (score=.964)
NKX2-5	ENSP00000327758³	STRING (score=.956)
FHL2	ENSP00000344266³	STRING (score=.953)
NFATC1	ENSP00000327850³	STRING (score=.922)
SOX15	ENSP00000355354³	STRING (score=.909)

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5/11 Gene Ontology (GO) biological process terms (links to tree view) (see all 11 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0001525	angiogenesis	IEA	--
GO:0001707	mesoderm formation	IEA	--
GO:0001829	trophectodermal cell differentiation	IEA	--
GO:0001892	embryonic placenta development	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for HAND1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HAND1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (HAND1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004821

Sigma-Aldrich siRNA for HAND1

Sigma-Aldrich shRNA for HAND1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004821

REFSEQ mRNAs for HAND1 gene:

NM_004821.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004821

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004821
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004821
                                 untagged cDNA clone in CMV expression vector: NM_004821

Additional cDNA sequence:

AF061756.1 BC021190.2 CR591821.1 CR594436.1 CR623464.1

1 DOTS entry:

DT.40300767

24/44 AceView cDNA sequences (see all 44 ):

AF061756 CR623464 AA570506 AW072675 BC021190 NM_004821 CR591821 BX375669

AI990698 AA552943 CR594436 BI194869 AI638877 BM684910 BQ072228 BM012688

BE260728 BE314849 AA936953 AW615154 BM684815 BE463740 BI200151 AL524188

highest scoring ESTs for HAND1:

AA570506 AA936953 AF061756 AI638877 AI990698 AW615154 BC021190 BE260728 BE312853 BE312914

Unigene Cluster for HAND1:

Heart and neural crest derivatives expressed 1

Hs.152531 [show with all ESTs]

Unigene Representative Sequence: AF061756

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for HAND1

ExUns:	1a	·	1b	^	2
SP1:
SP2:

About this scheme

ECgene alternative splicing isoforms for HAND1

1 Ensembl transcript including schematic representation:

ENST00000231121

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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HAND1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for HAND1

¹ / ² / ³

4 probe-sets matching HAND1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
72359_at²^{, 3}	U95-E	1	1.00	1.00	0.52	0.88	AI638877	0.80	1.00	0.91	1
80907_at²^{, 3}	U95-D	1	1.00	1.00	0.98	1.13	AA570506	0.80	1.00	0.91	1
220138_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_004821	0.60	1.00	0.82	1
220138_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks HAND1 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CCTGTTGTGC

SOURCE GeneReport for Unigene cluster: Hs.152531
UniProtKB/Swiss-Prot: HAND1_HUMAN, O96004
Tissue specificity: Heart

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for HAND1 gene from 5/7 species (see all 7 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	HAND1¹	--	heart and neural crest derivatives expressed 1	92.4(n) 97.21(a)	489164 XM_546282.2 XP_546282.2
chimpanzee (Pan troglodytes)	HAND1¹	--	heart and neural crest derivatives expressed 1	99.22(n) 99.53(a)	462209 XM_518050.2 XP_518050.2
cow (Bos taurus)	HAND1¹	--	heart and neural crest derivatives expressed 1	93.33(n) 98.14(a)	517952 NM_001075761.1 NP_001069229.1
rat (Rattus norvegicus)	Hand1¹	--	heart and neural crest derivatives expressed 1	87.91(n) 93.95(a)	59112 NM_021592.2 NP_067603.1
mouse (Mus musculus)	Hand1^{1, 5}	11 (32.00 cM)⁵	heart and neural crest derivatives expressed transcript more^{1, 5}	86.98(n)¹ 92.56(a)¹	15110¹ NM_008213.2¹ NP_032239.1¹ AK146084⁵ AL732587⁵ (see all 10)

About this table Species with no ortholog for HAND1

ENSEMBL Gene Tree for HAND1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for HAND1 gene

TWIST1² TCF15² SCXB² HAND2² SCXA²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/17 NCBI SNPs in HAND1 are shown (see all 17 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 35)

AB	SNP ID	Valid	Chr 5 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs2351484^1,2	C,F	153838362(+)	`CttttG/Catttt`	1	--	ng3¹		3		NA	116
	rs993098^1,2	A,C	153837889(+)	`GGGCAA/CGGCTG`	1	--	ut5¹ ese³		1		MN	184
	rs12516110^1,2	C	153838171(+)	`ACTCAG/TCTCCC`	1	--	ng3¹		0	--	--	--	--
	rs1846966^1,2	A,C,F,H	153837167(+)	`TGAGGC/GTGCTC`	1	--	int¹		12		NA EA EU WA	1032
	rs924581^1,2	C,F,H	153836082(+)	`TGCAGG/ACTTGG`	1	--	int¹		10		EA NA EU WA	596
	rs11748765^1,2	A,C	153837189(+)	`ACCCTA/TGGCTG`	1	--	int¹		0	--	--	--	--
--	rs60105264^1,2	--	153838638(+)	`TACCAC/GCCCGC`	1	--	ng3¹		0	--	--	--	--
	rs35542711^1,2	--	153834907(+)	`AGGGAA/TAGCTT`	1	--	ut3¹		0	--	--	--	--
--	rs13171812^1,2	--	153837788(+)	`CGCCGC/TCAGCC`	1	--	ut5¹ ese³		0	--	--	--	--
--	rs7708931^1,2	--	153839229(+)	`GGGCTC/TTCCCC`	1	--	ng3¹ tfbs³		0	--	--	--	--

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HapMap Linkage Disequilibrium images for HAND1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602406

Human Gene Mutation Database: HAND1

(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/44 PubMed articles for HAND1 gene (see all 44 ):

Molecular cloning of the human Hand1 gene/cDNA and its tissue-restricted expression in cytotrophoblastic cells and heart. (PubMed id 9931445)^{1, 2, 3, 4} Knofler M....Egarter C. (1998)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Cloning, chromosomal mapping, and expression of the human eHAND gene. (PubMed id 9337404)^{2, 3} Russell M.W....Izumo S. (1997)
Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains. (PubMed id 11802795)^{1, 3} Knofler M....Husslein P. (2002)
Negative regulation of selected bHLH proteins by eHAND. (PubMed id 10837146)^{1, 3} Bounpheng M.A....Christy B.A. (2000)
Differential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2. (PubMed id 15509787)^{1, 3} Hill A.A. and Riley P.R. (2004)
A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts. (PubMed id 18276607)^{1, 3} Reamon-Buettner S.M....Borlak J. (2008)
HAND1 gene expression is negatively regulated by the High Mobility Group A1 proteins and is drastically reduced in human thyroid carcinomas. (PubMed id 19060921)³ Martinez Hoyos J....Fusco A. (2009)
MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters. (PubMed id 16043483)³ Morin S....Nemer M. (2005)
PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation. (PubMed id 14636580)³ Firulli B.A....Firulli A.B. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 9421	HGNC: 4807	AceView: HAND1	Ensembl:ENSG00000113196	euGenes: HUgn9421
ECgene: HAND1	H-InvDB: HAND1

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for HAND1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for HAND1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for HAND1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for HAND1		Antibodies for HAND1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for HAND1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	shRNA in GFP-retroviral vector

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HAND1 Gene

protein-coding GIFtS: 56

Aliases &
Descriptions
for HAND1

Summaries
for HAND1

Genomic Location
for HAND1

Proteins
for HAND1

Protein Domains/
Families
for HAND1

Gene Function
for HAND1

Pathways & Interactions
for HAND1

Drugs & Compounds
for HAND1

Transcripts
for HAND1

Expression
for HAND1

Orthologs
for HAND1

Paralogs
for HAND1

SNPs/Variants
for HAND1

Disorders & Mutations
for HAND1

Medical News
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Publications
for HAND1

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Genome Databases showing HAND1

Other Databases showing HAND1

Specialized Databases showing HAND1

Licensable Technologies
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Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

HAND1 Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor HAND1

Summariesfor HAND1

Genomic Locationfor HAND1

Proteinsfor HAND1

Protein Domains/Familiesfor HAND1

Gene Functionfor HAND1

Pathways & Interactionsfor HAND1

Drugs & Compoundsfor HAND1

Transcriptsfor HAND1

Expression for HAND1

Orthologsfor HAND1

Paralogsfor HAND1

SNPs/Variantsfor HAND1

Disorders & Mutationsfor HAND1

Medical Newsfor HAND1

Publicationsfor HAND1

Search for HAND1

Genome Databases showing HAND1

Other Databases showing HAND1

Specialized Databases showing HAND1

Licensable Technologiesfor HAND1

Servicesfor HAND1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for HAND1

Summaries
for HAND1

Genomic Location
for HAND1

Proteins
for HAND1

Protein Domains/
Families
for HAND1

Gene Function
for HAND1

Pathways & Interactions
for HAND1

Drugs & Compounds
for HAND1

Transcripts
for HAND1

Expression
for HAND1

Orthologs
for HAND1

Paralogs
for HAND1

SNPs/Variants
for HAND1

Disorders & Mutations
for HAND1

Medical News
for HAND1

Publications
for HAND1

Licensable Technologies
for HAND1

Services
for HAND1