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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HAMP Gene

protein-coding   GIFtS: 53
GCID: GC19P035773

hepcidin antimicrobial peptide

 Explore 66 diseases affiliated with
HAMP via our new
 Human Malady Compendium 
Biological research products
for HAMP
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Hepcidin Antimicrobial Peptide1 2     Liver-Expressed Antimicrobial Peptide 12 3
HEPC1 2 3 5     Putative Liver Tumor Regressor2 3
LEAP11 2 3 5     PLTR2 3
HFE2B1 2 5     Hepcidin1
LEAP-11 3     

External Ids:    HGNC: 155981   Entrez Gene: 578172   Ensembl: ENSG000001056977   OMIM: 6064645   UniProtKB: P811723   

Export aliases for HAMP gene to outside databases

Previous GC identifers: GC19P036390 GC19P036222 GC19P040447 GC19P040465 GC19P032282


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HAMP:
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the
regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is
post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in
cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit
antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis,
a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. (provided
by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: HEPC_HUMAN, P81172
Function: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in
conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages (By similarity)
Function: Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus
and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa

Gene Wiki entry for HAMP


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HAMP gene promoter:
         COUP-TF1   COUP-TF   p300   COUP   STAT3   HNF-4alpha2   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHAMP promoter sequence
   Search SABiosciences Chromatin IP Primers for HAMP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HAMP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.1   Ensembl cytogenetic band:  19q13.12   HGNC cytogenetic band: 19q13.1

HAMP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HAMP gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P035773:  view genomic region     (about GC identifiers)

Start:
35,773,410 bp from pter      End:
35,776,046 bp from pter
Size:
2,637 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: HEPC_HUMAN, P81172 (See protein sequence)
Recommended Name: Hepcidin precursor  
Size: 84 amino acids; 9408 Da
Subcellular location: Secreted
Mass spectrometry: Mass=2789.8; Method=MALDI; Range=60-84; Source=PubMed:11034317;
4 PDB 3D structures from and Proteopedia for HAMP:
1M4E (3D)        1M4F (3D)        2KEF (3D)        3H0T (3D)    
Secondary accessions: Q1HE14 Q9BY68

Explore the universe of human proteins at neXtProt for HAMP: NX_P81172

HAMP Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_066998.1  
ENSEMBL proteins: 
 ENSP00000222304  

Human Recombinant Protein Products: 
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Novus Biologicals HAMP Protein
Novus Biologicals HAMP Lysate
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Browse ProSpec Recombinant Proteins
Browse Proteins at Uscn

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region NAS11034317
GO:0005737cytoplasm ----
GO:0045179apical cortex ----


HAMP for ontologies           About GeneDecksing



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ThermoFisher Antibodies for HAMP

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Browse ELISAs and CLIAs at Uscn


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HAMP for domains           About GeneDecksing

1 InterPro domain/family:
 IPR010500 Hepcidin

Graphical View of Domain Structure for InterPro Entry P81172

ProtoNet protein and cluster: P81172

1 Blocks protein family: IPB010500 Hepcidin

UniProtKB/Swiss-Prot: HEPC_HUMAN, P81172
Similarity: Belongs to the hepcidin family


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

     UniProtKB/Swiss-Prot: HEPC_HUMAN, P81172
Function: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in
conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages (By similarity)
Function: Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus
and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa

miRNA
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Search QIAGEN for miScript miRNA Assays for microRNAs that regulate HAMP
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
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OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HAMP (see all 4)
OriGene shRNA RFP: HAMP
OriGene siRNA: HAMP
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HAMP

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In Situ Assay
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Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for HAMP

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005179hormone activity IEA--


HAMP for ontologies           About GeneDecksing


1 GenomeRNAi human phenotype for HAMP:
 Decreased Hepatitis C virus re 

Animal Models:
     Mouse knock-outs for HAMP: Hamptm1Lex Hamptm1Svl
     4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Hamp):
 growth/size  hematopoietic system  homeostasis/metabolism  immune system 

HAMP for phenotypes           About GeneDecksing


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways  About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1iron metabolism in placenta
iron metabolism in placenta1.00


1 BioSystems Pathway for HAMP 
    iron metabolism in placenta


Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HAMP

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for HAMP (P811723 ENSP000002223044) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
SLC40A1Q9NP593, ENSP000002610244I2D: score=2 STRING: ENSP00000261024
CKAP4ENSP000003672654STRING: ENSP00000367265
About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006879cellular iron ion homeostasis IEA--
GO:0006955immune response TAS11113131
GO:0031640killing of cells of other organism IEA--
GO:0042742defense response to bacterium IEA--
GO:0050832defense response to fungus IEA--


HAMP for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

HAMP for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for HAMP

1 HMDB Compound for HAMP    About this table
CompoundSynonyms CAS #PubMed Ids
IronArmco iron (see all 19)7439-89-6--
5 Novoseek chemical compound relationships for HAMP gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
iron 84.2 142 16103673 (6), 16629180 (4), 12606179 (4), 15725899 (4) (see all 66)
anti-fungal 4.44 3 16629180 (1), 12138110 (1)
ethanol 0 1 16737972 (1)
oxygen 0 1 16460831 (1)
creatinine 0 2 19857675 (1)

Search CenterWatch for drugs/clinical trials and news about HAMP / HEPC 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for HAMP gene: 
NM_021175.2  

Unigene Cluster for HAMP:

Hepcidin antimicrobial peptide
Hs.743276  [show with all ESTs]
Unigene Representative Sequence: DR004094
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000222304(uc002nyw.3)

miRNA
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Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HAMP (see all 4)
OriGene shRNA RFP: HAMP
OriGene siRNA: HAMP
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HAMP
Clone
Products:
     
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HAMP
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
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OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HAMP
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAMP
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAMP

Additional cDNA sequence: 

AF131292.1 AF147355.1 AF309489.1 AJ277280.1 AY358669.1 BC020612.1 

3 DOTS entries:

DT.104663  DT.100018766  DT.100018767 

20 AceView cDNA sequences:

AF309489 AF147355 BX089371 AJ277280 BC020612 BM719679 AY358669 AI797446 
NM_021175 BM684049 CB116625 AK096110 T48278 AF131292 T48277 BG562482 
AI829866 AI937227 BU587812 BP346863 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

HAMP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTCCAGAGGC

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)

About this image
See HAMP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HAMP

SOURCE GeneReport for Unigene cluster: Hs.743276

UniProtKB/Swiss-Prot: HEPC_HUMAN, P81172
Tissue specificity: Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils,
salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine

    SABiosciences Expression via Pathway-Focused PCR Array including HAMP: 
          Cardiotoxicity in human mouse rat

Primer
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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAMP
In Situ
Assay Products:
 

 
Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for HAMP

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and mouse.

Orthologs for HAMP gene from 1/5 species (see all 5)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Hamp5 hepcidin antimicrobial peptide   --   7 (19.27 cM) 30942371 


ENSEMBL Gene Tree for HAMP (if available)
TreeFam Gene Tree for HAMP (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/88 NCBI SNPs in HAMP are shown (see all 88    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 19 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1048946951,2
Cpathogenic35775856(+) AGAGGC/TGAAGG 2 R * stg10--------
rs1048946961,2
C,F,pathogenic35775902(+) CTGCGG/ACTGCT 2 /D /G mis12Minor allele frequency- A:0.00NA EU 5875
rs18826951,2
C,F,A,H,--35771517(+) ACACAA/GTCACG 1 -- us2k1 tfbs38Minor allele frequency- G:0.22WA NA CSA EA 368
rs1478168321,2
--35771566(+) CACAGC/GCAAGT 1 -- us2k10--------
rs754481481,2
F,--35771623(+) GGAGCC/TTCCCA 1 -- us2k12Minor allele frequency- T:0.07WA EA 238
rs757145551,2
--35771728(+) TTCCTC/TGACAA 1 -- us2k12Minor allele frequency- T:0.07CSA WA 120
rs1413119901,2
--35771732(+) TCGACA/GACAAC 1 -- us2k10--------
rs1452640851,2
--35771799(+) AAGAGG/TCAAAA 1 -- us2k10--------
rs668688581,2
C,F,--35771850(+) TGGGCC/TGTGTG 1 -- us2k17Minor allele frequency- T:0.26WA NA CSA EA 366
rs1813056561,2
--35771948(+) GGAACC/TGGCTC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for HAMP (35773410 - 35776046 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for HAMP
     1 CNV: 4078
Human Gene Mutation Database (HGMD): HAMP

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HAMP
DNA2.0 Custom Variant and Variant Library Synthesis for HAMP

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

HAMP for disorders           About GeneDecksing

OMIM gene information: 606464   
OMIM disorders: 613313  
UniProtKB/Swiss-Prot: HEPC_HUMAN, P81172
  • Defects in HAMP are the cause of hemochromatosis type 2B (HFE2B) [MIM:613313]; also known as juvenile
  • hemochromatosis (JH). HFE2B is a disorder of iron metabolism with excess deposition of iron in the tissues, bronze
    skin pigmentation, hepatic cirrhosis, arthropathy and diabetes. The most common symptoms of hemochromatosis type 2 at
    presentation are hypogonadism and cardiomyopathy

    20/66 diseases for HAMP (see all 66):    About MalaCards
    hemochromatosis, type 2b    hemochromatosis type 2    iron overload    hemochromatosis
    open-angle glaucoma    porphyria cutanea tarda    congenital dyserythropoietic anemia type i    cardiomyopathy
    congenital dyserythropoietic anemia    primary open angle glaucoma    dyserythropoietic anemia    iron deficiency anemia
    polycythemia vera    beta thalassemia    mycobacterial infection    polycystic ovary syndrome
    biliary atresia    fatty liver disease    porphyria    systemic lupus erythematosus

    8 diseases from the University of Copenhagen DISEASES database for HAMP:
    Hemochromatosis     Anemia     Nutrition disease     Thalassemia
    Aceruloplasminemia     Liver disease     Kidney disease     Hepatitis C

    7 Novoseek disease relationships for HAMP gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hemochromatosis, juvenile 93.8 15 15099344 (1), 16234038 (1), 16493621 (1), 18762941 (1) (see all 14)
    iron overload 90.9 23 12915468 (2), 12183449 (2), 16103673 (2), 18809758 (2) (see all 16)
    hemochromatosis 87.4 27 16103673 (4), 16234038 (1), 19625109 (1), 15198949 (1) (see all 12)
    hereditary hemochromatosis 86.8 6 15024747 (2), 14670915 (1), 16103673 (1), 19342478 (1) (see all 5)
    anemia 54.1 6 16838333 (2), 18544472 (1), 19541813 (1), 20019408 (1) (see all 5)
    inflammation 39.9 7 18775801 (1), 19478464 (1), 15315977 (1), 17218383 (1) (see all 5)
    response acute phase 29.8 2 15725899 (1), 15973703 (1)

    GeneTests: HAMP
    Juvenile Hemochromatosis

    Genetic Association Database (GAD): HAMP
    Human Genome Epidemiology (HuGE) Navigator: HAMP (17 documents)

    Export disorders for HAMP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HAMP gene, integrated from 9 sources (see all 310):
    (articles sorted by number of sources associating them with HAMP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype. (PubMed id 14670915)1, 2, 4, 9 Jacolot S.... Ferec C. (2004)
    2. LEAP-1, a novel highly disulfide-bonded human peptide exhibits antimicrobial activity. (PubMed id 11034317)1, 2, 3 Krause A.... Adermann K. (2000)
    3. Digenic inheritance of mutations in HAMP and HFE results in different types of haemochromatosis. (PubMed id 12915468)1, 2, 9 Merryweather-Clarke A.T....Robson K.J. (2003)
    4. The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis. (PubMed id 12138110)1, 2, 9 Hunter H.N.... Vogel H.J. (2002)
    5. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. (PubMed id 11113132)1, 3, 9 Pigeon C....Loreal O. (2001)
    6. Hepcidin: a urinary antimicrobial peptide synthesized in the liver. (PubMed id 11113131)1, 2, 9 Park C.H.... Ganz T. (2001)
    7. Hepcidin revisited, disulfide connectivity, dynamics, and structure. (PubMed id 19553669)1, 2 Jordan J.B....Sasu B.J. (2009)
    8. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
    9. Screening hepcidin for mutations in juvenile hemochromatosis: identification of a new mutation (C70R). (PubMed id 14630809)1, 2 Roetto A.... Camaschella C. (2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57817 HGNC: 15598 AceView: HAMP Ensembl:ENSG00000105697 euGenes: HUgn57817
    ECgene: HAMP H-InvDB: HAMP

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HAMP Pharmacogenomics, SNPs, Pathways
    GeneReviewshttp://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/HAMP
    Wikipedia http://en.wikipedia.org/wiki/Hepcidin

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HAMP gene:
    Search GeneIP for patents involving HAMP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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