V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

HACL1 Gene

protein-coding GIFtS: 53

GC03M015579

2-hydroxyacyl-CoA lyase 1
(Previous name: 2-hydroxyphytanoyl-CoA lyase )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: HPCL)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
1600020H07Rik ^²
2-HPCL ^¹, ², ³
EC 4.1.-.- ^³
FLJ55041 ^²
HPCL ^², ³
HPCL2 ^², ³
PHYH2 ^¹, ², ³

Descriptions
2-hydroxyacyl-CoA lyase 1 ^²
2-hydroxyphytanol-CoA lyase ^²
2-hydroxyphytanoyl-CoA lyase ^¹, ², ³
Phytanoyl-CoA 2-hydroxylase 2 ^², ³
phytanoyl-CoA hydroxylase 2 ^²

External Ids
HGNC: 17856¹
Entrez Gene: 26061²
UniProtKB: Q9UJ83³
Ensembl: ENSG00000131373⁷

Search outside databases for aliases for HACL1 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: HACL1_HUMAN, Q9UJ83

Function: Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into

formyl-CoA and a 2-methyl-branched fatty aldehyde

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the HACL1 gene

Entrez Gene cytogenetic band: 3p24.3 Ensembl cytogenetic band: 3p24.3 HGNC cytogenetic band: 3p24.3

HACL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03M015579: (about GC identifiers)

Start:	15,577,243 bp from pter
End:	15,618,134 bp from pter
Size:	40,892 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000003.10 NT_022517.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: HACL1_HUMAN, Q9UJ83 (See protein sequence)

Recommended Name: 2-hydroxyacyl-CoA lyase 1

Size: 578 amino acids; 63729 Da

Cofactor: Binds 1 magnesium ion per subunit

Cofactor: Binds 1 thiamine pyrophosphate per subunit

Subunit: Homotetramer

Subcellular location: Peroxisome

Secondary accessions: Q9BV42 Q9P0A2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_036392.2

ENSEMBL proteins:

ENSP00000373289 ENSP00000323811

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (2 Hydroxy phytanoyl CoA lyase )
	Human Recombinant Proteins from Abnova (PHYH2)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005777	peroxisome	IDA	10468558 14561759

About this table

Antibodies for HACL1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for HACL1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (2 Hydroxy phytanoyl CoA lyase ), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (PHYH2)
	Novus Biologicals Antibody for HACL1

Assays for HACL1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9UJ83

ProtoNet protein and cluster: Q9UJ83

2 Blocks protein families:

IPB000399 Pyruvate decarboxylase

IPB011766 Thiamine pyrophosphate enzyme

UniProtKB/Swiss-Prot: HACL1_HUMAN, Q9UJ83

Similarity: Belongs to the TPP enzyme family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HACL1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (PHYH2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012260

Applied Biosystems Silencer® siRNAs for HACL1

Sigma-Aldrich siRNA for HACL1

Sigma-Aldrich shRNA for HACL1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for HACL1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_012260
Myc/DDK tagged cDNA clone in CMV expression vector: NM_012260
untagged cDNA clone in CMV expression vector: NM_012260

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_012260

UniProtKB/Swiss-Prot: HACL1_HUMAN, Q9UJ83

Function: Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into

formyl-CoA and a 2-methyl-branched fatty aldehyde

Catalytic activity: 2-hydroxyphytanoyl-CoA = pristanal + formyl-CoA

Enzyme Number (IUBMB): EC 4.1.-.-

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000287	magnesium ion binding	IEA	--
GO:0016830	carbon-carbon lyase activity	IDA	10468558
GO:0030976	thiamin pyrophosphate binding	IDA	10468558
GO:0042802	identical protein binding	IPI	16189514

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: HACL1_HUMAN, Q9UJ83

Pathway: Lipid metabolism; fatty acid metabolism

2 Interacting proteins for HACL1 (Q9UJ83^{1, 2}) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HACL1	Q9UJ83¹^,²	EBI-746580, EBI-746580 MINT-67228 EBI-746580, EBI-746580 MINT-67228
HACL1	Q9UJ83¹^,²	EBI-746580, EBI-746580 MINT-67228 EBI-746580, EBI-746580 MINT-67228
ZMYND19	Q96E35²	MINT-66872

About this table
2 Gene Ontology (GO) biological process terms (links to tree view):
GO ID Qualified GO term Evidence PubMed IDs
GO:0001561 fatty acid alpha-oxidation IDA 10468558
GO:0006629 lipid metabolic process IEA --
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for HACL1
3 Novoseek chemical compound relationships for HACL1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
2-hydroxyphytanoyl-coa	99.50	15	10521701 (3), 10468558 (2), 10754307 (1), 16796018 (1) (see all 9)
formyl-coa	97.18	2	16796018 (1)
phytanic acid	95.18	5	16786225 (1), 10521701 (1), 10896309 (1), 11948235 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HACL1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (PHYH2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012260

Sigma-Aldrich siRNA for HACL1

Sigma-Aldrich shRNA for HACL1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_012260

REFSEQ mRNAs for HACL1 gene:

NM_012260.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_012260

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_012260
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_012260
                                 untagged cDNA clone in CMV expression vector: NM_012260

Additional cDNA sequence:

AF161397.1 AJ131753.1 AK056977.1 AK301546.1 AK301990.1 AK302086.1 BC001627.1 BC007440.2

CR608246.1 CR609501.1

21 DOTS entries:

DT.416311 DT.100804747 DT.92442759 DT.101974633 DT.120886761 DT.315966 DT.120886740 DT.416313

DT.100804752 DT.120886833 DT.40193790 DT.120886839 DT.100737498 DT.101962225 DT.100762559 DT.120886731

DT.120886743 DT.75192882 DT.91684326 DT.95130837 DT.97846094

24/264 AceView cDNA sequences (see all 264 ):

CN479599 BM694820 AA039835 CA441883 BM017121 AA564217 CF243126 BU527364

BF434073 AF161397 AA298294 BM670044 BU182873 AL043205 BM759883 CB145879

BM675556 BM126759 CR608246 AI636915 AV647242 BI820732 H10428 AI741764

highest scoring ESTs for HACL1:

AA071233 AF161397 AJ131753 AK056977 AL043205 AL600281 AL601151 BC001627 BC007440 BE249896

Unigene Cluster for HACL1:

2-hydroxyacyl-CoA lyase 1

Hs.63290 [show with all ESTs]

Unigene Representative Sequence: NM_012260

GeneLoc Exon Structure

5/20 Alternative Splicing Database (ASD) splice patterns (SP) for HACL1 (see all 20 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	·	2c	·	2d	^	3a	·	3b	^	4	^	5	^	6	^	7	^	8a	·	8b	^	9a	·	9b	^	10	^	11a	·	11b	^	12	^	13a	·	13b	^	14a	·	14b	^
SP1:									-		-				-				-																										-				-
SP2:									-		-				-				-				-														-								-				-
SP3:									-		-				-		-		-		-		-		-		-		-		-		-		-		-								-				-
SP4:									-		-				-				-						-		-
SP5:									-		-				-				-						-

ExUns:	15a	·	15b	^	16a	·	16b	^	17	^	18a	·	18b	·	18c
SP1:									-
SP2:									-
SP3:									-
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for HACL1

2 Ensembl transcripts including schematic representations:

ENST00000383779 ENST00000321169

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

HACL1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for HACL1

¹ / ² / ³

3 probe-sets matching HACL1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
53979_at²^{, 3}	U95-B	1	1.00	1.00	1.00	1.00	AL043205	0.80	1.00	0.91	1
223211_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BC001627	0.80	1.00	0.91	1
223211_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ATTGAGCCAC

SOURCE GeneReport for Unigene cluster: Hs.63290
UniProtKB/Swiss-Prot: HACL1_HUMAN, Q9UJ83
Tissue specificity: Expressed in high levels in liver, also expressed in kidney, heart and skeletal
muscle

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for HACL1 gene from 5/18 species (see all 18 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	HACL1¹	--	2-hydroxyacyl-CoA lyase 1	89.68(n) 88.93(a)	477060 XM_534256.2 XP_534256.2
chimpanzee (Pan troglodytes)	HACL1¹	--	2-hydroxyacyl-CoA lyase 1	99.65(n) 99.48(a)	743738 XM_001160528.1 XP_001160528.1
cow (Bos taurus)	HACL1¹	--	2-hydroxyacyl-CoA lyase 1	89.39(n) 89.1(a)	512676 XM_590233.3 XP_590233.3
rat (Rattus norvegicus)	Hacl1¹	--	2-hydroxyacyl-CoA lyase 1	85.58(n) 85.99(a)	85255 NM_053493.1 NP_445945.1
mouse (Mus musculus)	Hacl1^{1, 5}	14⁵	2-hydroxyacyl-CoA lyase 1^{1, 5}	85.7(n)¹ 87.89(a)¹	56794¹ NM_019975.2¹ NP_064359.2¹ AA734474⁵ AJ132139⁵ (see all 10)

About this table Species with no ortholog for HACL1

ENSEMBL Gene Tree for HACL1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for HACL1 gene

ILVBL²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/174 NCBI SNPs in HACL1 are shown (see all 174 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 51)

AB	SNP ID	Valid	Chr 3 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs905650^1,2	C,F,H,O	15585074(-)	`TCCCTG/ACCTAT`	1	L/L	syn¹ ese³		20	NA EA MN EU WA	3049
	rs2271020^1,2	C,F,H	15584423(-)	`GGGCAA/GTGGAT`	1	Q/Q	syn¹ ese³		9	EA EU WA	2304
	rs6784844^1,2	A,C,F,H	15614448(+)	`CAACAC/TGTAAC`	1	--	int¹		6	EU EA WA NA	600
	rs6797119^1,2	A,C,F,H	15598766(+)	`atataC/Tactaa`	1	--	int¹		4	EU EA WA	412
	rs7648958^1,2	A,C,F,H	15596147(+)	`tccagG/Acacat`	1	--	int¹		8	EU EA WA NA	780
	rs9827194^1,2	C,F,H	15582085(+)	`GAATGT/GAGGTT`	1	--	int¹		7	EU EA WA NA	560
	rs2134784^1,2	C,F,H	15613264(-)	`ATAAAC/TCCCTC`	1	--	int¹		11	NA EU EA WA	980
	rs10510440^1,2	C,F,H	15582006(+)	`AAAGGA/GGTATT`	1	--	int¹ trp³		20	NS EU EA WA NA	1500
	rs1979896^1,2	A,C,H	15602265(+)	`AGCTAA/CAATGT`	1	--	int¹		1	EU	120
	rs17485390^1,2	C,F,H	15587217(+)	`AGTAGT/CAGACA`	1	--	int¹		16	NA EU EA WA	1474

About this table

HapMap Linkage Disequilibrium images for HACL1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 604300

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/17 PubMed articles for HACL1 gene (see all 17 ):

Purification, molecular cloning, and expression of 2-hydroxphytanoyl- CoA lyase, a peroxisomal thiamine hydrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3- methyl-branched fatty acids. (PubMed id 10468558)^{1, 2, 3, 4} Foulon V.... Casteels M. (1999)
Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids. (PubMed id 15644336)^{2, 3} Foulon V....Casteels M. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{3, 4} Zhang Q.H....Chen Z. (2000)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)³ Kimura K.... Sugano S. (2006)
Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)³ Rual J.F....Vidal M. (2005)
Proteomic analysis of rat liver peroxisome: presence of peroxisome- specific isozyme of Lon protease. (PubMed id 14561759)³ Kikuchi M....Taniguchi H. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
Phytanic acid alpha-oxidation: identification of 2-hydroxyphytanoyl-CoA lyase in rat liver and its localisation in peroxisomes. (PubMed id 10521701)¹ Jansen G.A....Wanders R.J. (1999)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 26061	HGNC: 17856	AceView: HPCL2	Ensembl:ENSG00000131373	euGenes: HUgn26061
ECgene: HACL1	H-InvDB: HACL1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for HACL1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for HACL1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for HACL1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for HACL1		Antibodies for HACL1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for HACL1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (PHYH2)
	Antibodies (PHYH2)
	Chimera RNAi (PHYH2)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (2 Hydroxy phytanoyl CoA lyase )
	Antibodies (2 Hydroxy phytanoyl CoA lyase )

Search OriGene for HACL1

Search Tocris compounds for HACL1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for HACL1

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
HACL1 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

HACL1 Gene

protein-coding GIFtS: 53

Aliases &
Descriptions
for HACL1

Summaries
for HACL1

Genomic Location
for HACL1

Proteins
for HACL1

Protein Domains/
Families
for HACL1

Gene Function
for HACL1

Pathways & Interactions
for HACL1

Drugs & Compounds
for HACL1

Transcripts
for HACL1

Expression
for HACL1

Orthologs
for HACL1

Paralogs
for HACL1

SNPs/Variants
for HACL1

Disorders & Mutations
for HACL1

Medical News
for HACL1

Publications
for HACL1

Search for HACL1

Genome Databases showing HACL1

Other Databases showing HACL1

Specialized Databases showing HACL1

Licensable Technologies
for HACL1

Services
for HACL1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

HACL1 Gene

protein-coding GIFtS: 53

Aliases & Descriptionsfor HACL1

Summariesfor HACL1

Genomic Locationfor HACL1

Proteinsfor HACL1

Protein Domains/Familiesfor HACL1

Gene Functionfor HACL1

Pathways & Interactionsfor HACL1

Drugs & Compoundsfor HACL1

Transcriptsfor HACL1

Expression for HACL1

Orthologsfor HACL1

Paralogsfor HACL1

SNPs/Variantsfor HACL1

Disorders & Mutationsfor HACL1

Medical Newsfor HACL1

Publicationsfor HACL1

Search for HACL1

Genome Databases showing HACL1

Other Databases showing HACL1

Specialized Databases showing HACL1

Licensable Technologiesfor HACL1

Servicesfor HACL1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for HACL1

Summaries
for HACL1

Genomic Location
for HACL1

Proteins
for HACL1

Protein Domains/
Families
for HACL1

Gene Function
for HACL1

Pathways & Interactions
for HACL1

Drugs & Compounds
for HACL1

Transcripts
for HACL1

Expression
for HACL1

Orthologs
for HACL1

Paralogs
for HACL1

SNPs/Variants
for HACL1

Disorders & Mutations
for HACL1

Medical News
for HACL1

Publications
for HACL1

Licensable Technologies
for HACL1

Services
for HACL1