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HABP4 Gene

protein-coding   GIFtS: 54
GCID: GC09P099212

Hyaluronan Binding Protein 4

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Hyaluronan Binding Protein 41 2     SERBP1L2
Ki-1/57 Intracellular Antigen2 3     Chromodomain Helicase DNA Binding Protein 3 Interacting Protein2
IHABP-42 3     Intracellular Antigen Detected By Monoclonal Antibody Ki-12
IHABP42 3     Intracellular Hyaluronan-Binding Protein 42
Ki-1/572     

External Ids:    HGNC: 170621   Entrez Gene: 229272   Ensembl: ENSG000001309567   UniProtKB: Q5JVS03   

Export aliases for HABP4 gene to outside databases

Previous GC identifers: GC09P090026 GC09P090956 GC09P092669 GC09P094592 GC09P096292 GC09P098252 GC09P068823


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for HABP4 Gene:
HABP4 (hyaluronan binding protein 4) is a protein-coding gene. An important paralog of this gene is SERBP1.

UniProtKB/Swiss-Prot: HABP4_HUMAN, Q5JVS0
Function: May be involved in nuclear functions such as the remodeling of chromatin and the regulation of
transcription

Gene Wiki entry for HABP4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HABP4 gene promoter:
         p53   p300   LUN-1   E4BP4   AP-2gamma   FOXJ2 (long isoform)   FOXJ2   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHABP4 promoter sequence
   Search Chromatin IP Primers for HABP4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HABP4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.3-q31   Ensembl cytogenetic band:  9q22.32   HGNC cytogenetic band: 9q22.3-q31

HABP4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HABP4 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P099212:  view genomic region     (about GC identifiers)

Start:
99,212,414 bp from pter      End:
99,253,618 bp from pter
Size:
41,205 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: HABP4_HUMAN, Q5JVS0 (See protein sequence)
Recommended Name: Intracellular hyaluronan-binding protein 4  
Size: 413 amino acids; 45785 Da
Subunit: Interacts with the C-terminus of CHD3. Interacts via its C-terminal region with GNB2L1. Interacts with
p53/TP53
Miscellaneous: Able to bind hyaluronan. However, its intracellular localization suggests that this interaction may
not be relevant in vivo
Miscellaneous: The interaction with GNB2L1 is abolished upon activation of L540 tumor cells with PMA, which
results in phosphorylation and exit of HABP4 from the nucleus
Secondary accessions: O75804 Q8WV33 Q9NYJ2
Alternative splicing: 2 isoforms:  Q5JVS0-1   Q5JVS0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for HABP4: NX_Q5JVS0

Explore proteomics data for HABP4 at MOPED

Post-translational modifications: 

  • Phosphorylated by phorbol 12-myristate 13-acetate (PMA)-activated PKC isoforms at Thr-354 and Thr-375 (Probable)1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HABP4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055097.2  
    ENSEMBL proteins: 
     ENSP00000364400   ENSP00000364398  
    Reactome Protein details: Q5JVS0

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR006861 HABP4_PAIRBP1-bd

    Graphical View of Domain Structure for InterPro Entry Q5JVS0

    ProtoNet protein and cluster: Q5JVS0


    Find genes that share domains with HABP4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HABP4_HUMAN, Q5JVS0
    Function: May be involved in nuclear functions such as the remodeling of chromatin and the regulation of
    transcription

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI15862299
         
    Find genes that share ontologies with HABP4           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for HABP4

    miRNA
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    miRTarBase miRNAs that target HABP4:
    hsa-mir-19b-3p (MIRT031235), hsa-mir-130b-3p (MIRT020318)

    Block miRNA regulation of human, mouse, rat HABP4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HABP4 (see all 42):
    hsa-miR-579 hsa-miR-345 hsa-let-7d hsa-miR-106a hsa-miR-134 hsa-miR-301a hsa-miR-519a hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidHABP4 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat HABP4

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HABP4_HUMAN, Q5JVS0: Cytoplasm. Nucleus. Note=Transported into the nuclear compartment in activated leukocytes
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol4
    extracellular4
    mitochondrion1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005634nucleus ISS--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm ISS--
    GO:0005829cytosol TAS--

    Find genes that share ontologies with HABP4           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for HABP4 About    
    See pathways by source

    SuperPathContained pathways About
    1Response to elevated platelet cytosolic Ca2+
    Response to elevated platelet cytosolic Ca2+0.94
    Platelet degranulation0.94
    2Hemostasis
    Hemostasis0.43
    Platelet activation, signaling and aggregation0.43


    Find genes that share SuperPaths with HABP4           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for HABP4
        Platelet degranulation


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HABP4
    Interactions:

        GeneGlobe Interaction Network for HABP4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for HABP4 (Q5JVS01, 2, 3 ENSP000003643984) via UniProtKB, MINT, STRING, and/or I2D (see all 52)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMN2Q166372, 3, ENSP000003701194MINT-7041217 I2D: score=1 STRING: ENSP00000370119
    C1QBPQ070212, 3, ENSP000002256984MINT-7041074 I2D: score=3 STRING: ENSP00000225698
    CIRBPQ140112, 3, ENSP000003228874MINT-8194629 I2D: score=1 STRING: ENSP00000322887
    COILP384322, 3, ENSP000002403164MINT-7041203 I2D: score=1 STRING: ENSP00000240316
    FXR1P511142, 3, ENSP000003501704MINT-8194614 I2D: score=1 STRING: ENSP00000350170
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    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002576platelet degranulation TAS--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0007596blood coagulation TAS--
    GO:0030168platelet activation TAS--

    Find genes that share ontologies with HABP4           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HABP4



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HABP4 gene: 
    NM_014282.3  

    Unigene Cluster for HABP4:

    Hyaluronan binding protein 4
    Hs.494567  [show with all ESTs]
    Unigene Representative Sequence: AK091242
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000375251(uc010msh.3) ENST00000375249(uc010msg.3) ENST00000466976

    miRNA
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    Block miRNA regulation of human, mouse, rat HABP4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate HABP4 (see all 42):
    hsa-miR-579 hsa-miR-345 hsa-let-7d hsa-miR-106a hsa-miR-134 hsa-miR-301a hsa-miR-519a hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidHABP4 3' UTR sequence
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      QuantiTect SYBR Green Assays in human, mouse, rat HABP4
      QuantiFast Probe-based Assays in human, mouse, rat HABP4

    Additional mRNA sequence: 

    AF241831.1 AK000610.1 AK025144.1 AK055161.1 AK091242.1 AK124836.1 BC018788.1 U77327.1 

    9 DOTS entries:

    DT.317227  DT.99930684  DT.95083940  DT.95356898  DT.92469976  DT.40109657  DT.95083928  DT.121174336 
    DT.91927322 

    Selected AceView cDNA sequences (see all 162):

    H43388 BM709568 BM689626 BU736928 AK000610 N34326 BU727478 CB158708 
    BU169284 AA593631 BM661599 CR613789 AI889924 AA904204 BE465800 BM719882 
    CR613476 BG760852 BC018788 BQ009655 BF475746 BF477812 BM761762 BG059636 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HABP4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGACTCTTA
    HABP4 Expression
    About this image


    HABP4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Epithelial Cells
             Fetal Matrix Cells Hair Follicle
     
     Hair (Integumentary System)
             Fetal Matrix Cells Hair Follicle
     
     Eye (Sensory Organs)
             Retina
     
     Testis (Reproductive System)
     
     Spinal Cord (Nervous System)
    HABP4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HABP4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.494567

    UniProtKB/Swiss-Prot: HABP4_HUMAN, Q5JVS0
    Tissue specificity: Highly expressed in brain, heart, and kidney, and moderately expressed in skeletal muscle.
    Also expressed in a variety of tumor cell lines and in activated but not resting leukocytes

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for HABP4 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Habp41 , 5 hyaluronic acid binding protein 41, 5 85(n)1
    85.4(a)1
      13 (33.26 cM)5
    565411  NM_019986.31  NP_064370.21 
     641618665 
    chicken
    (Gallus gallus)
    Aves HABP41 hyaluronan binding protein 4 63.56(n)
    55.08(a)
      395444  NM_204705.1  NP_990036.1 
    lizard
    (Anolis carolinensis)
    Reptilia HABP46
    hyaluronan binding protein 4
    60(a)
    1 ↔ 1
    2(39957374-39975216)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC059961.12   -- 76.22(n)    BC059961.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1034821 zgc:103482 59.97(n)
    58.76(a)
      450001  NM_001006022.1  NP_001006022.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG415036
    vig26
    (see all 3)
    vig2
    (see all 3)
    23(a)
    21(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    YHet(305269-307004)
    3R(20949095-20951341)


    ENSEMBL Gene Tree for HABP4 (if available)
    TreeFam Gene Tree for HABP4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HABP4 gene
    SERBP12  
    2 SIMAP similar genes for HABP4 using alignment to 1 protein entry:     HABP4_HUMAN:
    DKFZp686P17171    SERBP1

    Find genes that share paralogs with HABP4           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HABP4 (see all 790)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1503391611,2
    C--99210510(+) TTGTGA/CATAGT 1 -- us2k10--------
    rs1380401181,2
    --99210523(+) TGCTAC/TGAATA 1 -- us2k10--------
    rs1424257451,2
    --99210529(+) GAATAC/TTCATG 1 -- us2k10--------
    rs78701061,2
    C,F,A,H--99210584(+) AAAGCG/ATAGGC 1 -- us2k131Minor allele frequency- A:0.29NA NS EA WA CSA 2913
    rs599336991,2
    C,F--99210870(+) CTCTAA/TCTGGA 1 -- us2k12Minor allele frequency- T:0.05WA 120
    rs1446597121,2
    --99210931(+) CCTTAC/TATCAT 1 -- us2k10--------
    rs1386214081,2
    --99211099(+) AGAAGC/GGGGGG 1 -- us2k10--------
    rs1115168331,2
    C--99211100(+) GAAGGG/CGGGGA 1 -- us2k11Minor allele frequency- C:0.50WA 2
    rs1495149601,2
    C--99211220(+) AGGAA-/TTGGAA 1 -- us2k10--------
    rs745267451,2
    C,F--99211266(+) TGAGGC/ATGGAA 1 -- us2k11Minor allele frequency- A:0.08WA 118

    HapMap Linkage Disequilibrium report for HABP4 (99212414 - 99253618 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for HABP4:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2669547CNV Deletion23128226
    esv22781CNV Loss19812545
    nsv824998CNV Gain20364138
    nsv893604CNV Gain21882294
    nsv893603CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    Find genes that share disorders with HABP4           About GenesLikeMe

    Genetic Association Database (GAD): HABP4
    Human Genome Epidemiology (HuGE) Navigator: HABP4 (1 document)

    Export disorders for HABP4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HABP4 gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with HABP4)
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    1. Molecular characterization of a novel intracellular hyaluronan- binding protein. (PubMed id 10887182)1, 2, 3, 9 Huang L.... Toole B.P. (J. Biol. Chem. 2000)
    2. Characterization, mapping and partial cDNA sequence of the 57-kD intracellular Ki-1 antigen. (PubMed id 9523163)1, 2, 3 Kobarg J....Hansen H.P. (Exp. Clin. Immunogenet. 1997)
    3. Ki-1/57 interacts with RACK1 and is a substrate for the phosphorylation by phorbol 12-myristate 13-acetate-activated protein kinase C. (PubMed id 14699138)1, 2, 9 Nery F.C.... Kobarg J. (J. Biol. Chem. 2004)
    4. Confirmation of linkage to and localization of familial colon cancer risk haplotype on chromosome 9q22. (PubMed id 20551049)1, 4 Gray-McGuire C....Wiesner G.L. (Cancer Res. 2010)
    5. Evidence for the interaction of the regulatory protein Ki-1/57 with p53 and its interacting proteins. (PubMed id 16455055)1, 2 Nery F.C.... Kobarg J. (Biochem. Biophys. Res. Commun. 2006)
    6. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3. (PubMed id 12505151)1, 2 Lemos T.A.... Kobarg J. (FEBS Lett. 2003)
    9. Evidence for the association of the human regulatory protein Ki-1/57 with the translational machinery. (PubMed id 21771594)1 GonAsalves K.d.e. .A....Kobarg J. (FEBS Lett. 2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 22927 HGNC: 17062 AceView: HABP4 Ensembl:ENSG00000130956 euGenes: HUgn22927
    ECgene: HABP4 H-InvDB: HABP4

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HABP4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HABP4 gene:
    Search GeneIP for patents involving HABP4

    GeneCards and IP:
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