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HABP2 Gene

protein-coding GIFtS: 59

GC10P115302

hyaluronan binding protein 2
(Previous name: hyaluronan-binding protein 2 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EC 3.4.21.- ^³
FSAP ^¹, ², ³, ⁵
HABP ^¹, ²
HGFAL ^¹, ², ³, ⁵
OTTHUMP00000020505 ^²
PHBP ^¹, ², ³, ⁵

Descriptions
Factor VII-activating protease ^³
Factor seven-activating protease ^³
Hepatocyte growth factor activator-like protein ^², ³
Plasma hyaluronan-binding protein ^³
factor VII activating protein ^²
hyaluronan binding protein 2 ^²
hyaluronan-binding protein 2 ^¹
hyaluronic acid binding protein 2 ^²
plasma hyaluronan binding protein ^²

External Ids
HGNC: 4798¹
Entrez Gene: 3026²
UniProtKB: Q14520³
Ensembl: ENSG00000148702⁷

Search outside databases for aliases for HABP2 gene

Previous GC identifers: GC10P114208 GC10P114546 GC10P115444 GC10P114977

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for HABP2:

The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and

is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then

undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis

leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen

activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not

prothrombin, plasminogen, or the gamma chain of fibrinogen. [provided by RefSeq]

UniProtKB/Swiss-Prot: HABP2_HUMAN, Q14520

Function: Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and

'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of

the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate)

prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator

(pro-urokinase) to the active two chain form. Activates coagulation factor VII

Gene Wiki entry for HABP2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the HABP2 gene

Entrez Gene cytogenetic band: 10q25.3 Ensembl cytogenetic band: 10q25.3 HGNC cytogenetic band: 10q25.3

HABP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P115302: (about GC identifiers)

Start:	115,302,775 bp from pter
End:	115,339,348 bp from pter
Size:	36,574 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000010.9 NT_030059.12

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: HABP2_HUMAN, Q14520 (See protein sequence)

Recommended Name: Hyaluronan-binding protein 2 precursor

Size: 560 amino acids; 62672 Da

Subunit: Heterodimer; disulfide-linked. Heterodimer of a 50 kDa heavy and a 27 kDa light chain

linked by a disulfide bond (By similarity)

Subcellular location: Secreted. Note=Secreted as an inactive single-chain precursor and is then

activated to a heterodimeric form

Secondary accessions: O00663

Post-translational modifications:

Proteolytic cleavage at Gly-23 or Met-27 can give rise to the 50 kDa heavy chain and cleavage at

Arg-313 or Lys-319 can give rise to the 27 kDa light chain. The heavy chain can undergo further

proteolytic cleavage at Lys-169 or Arg-170 to give rise to 2 inactive 26 kDa fragments and the

light chain can undergo further proteolytic cleavage at Arg-480 to give rise to inactive 17 kDa

and 8 kDa fragments (By similarity)¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_004123.1

ENSEMBL proteins:

ENSP00000277903

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
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	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (HABP2)
	Human Recombinant Proteins from Abnova (HABP2)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	NAS	14718574
GO:0005615	extracellular space	TAS	8827452

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Antibodies for HABP2:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for HABP2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (HABP2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (HABP2)
	Novus Biologicals Antibodies for HABP2

Assays for HABP2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q14520

ProtoNet protein and cluster: Q14520

4 Blocks protein families:

IPB000001 Kringle

IPB001254 Serine protease

IPB001314 Chymotrypsin serine protease family (S1) signature

IPB006210 Type I EGF

UniProtKB/Swiss-Prot: HABP2_HUMAN, Q14520

Similarity: Belongs to the peptidase S1 family

Similarity: Contains 3 EGF-like domains

Similarity: Contains 1 kringle domain

Similarity: Contains 1 peptidase S1 domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HABP2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (HABP2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004132

Applied Biosystems Silencer® siRNAs for HABP2

Sigma-Aldrich siRNA and siRNA Panels for HABP2

Sigma-Aldrich shRNA Panels and shRNA for HABP2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for HABP2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004132
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004132
untagged cDNA clones in CMV expression vector (see all 2): NM_004132

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004132

UniProtKB/Swiss-Prot: HABP2_HUMAN, Q14520

Function: Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and

'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of

the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate)

prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator

(pro-urokinase) to the active two chain form. Activates coagulation factor VII

Enzyme Number (IUBMB): EC 3.4.21.-

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004252	serine-type endopeptidase activity	IEA	--
GO:0005539	glycosaminoglycan binding	TAS	8827452
GO:0008233	peptidase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for HABP2 (Your Favorite Gene powered by Ingenuity)

Lysine Degradation

GeneDecks HABP2 for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for HABP2

2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006508	proteolysis	IEA	--
GO:0007155	cell adhesion	TAS	8827452

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for HABP2
4 Novoseek chemical compound relationships for HABP2 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
heparan sulfate	42.34	3	15035435 (1), 16972797 (1)
fibrinogen	27.42	3	11217080 (2), 15320789 (1)
phosphatidylethanolamine	20.80	1	15320789 (1)
calcium	0.00	3	11432747 (1), 15654766 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HABP2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (HABP2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004132

Sigma-Aldrich siRNA and siRNA Panels for HABP2

Sigma-Aldrich shRNA Panels and shRNA for HABP2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004132

REFSEQ mRNAs for HABP2 gene:

NM_004132.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004132

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004132
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004132
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_004132

Additional cDNA sequence:

AK290832.1 AK303759.1 AK303761.1 AK303948.1 BC031412.1 D49742.1 S83182.1

3 DOTS entries:

DT.418518 DT.100789919 DT.99981377

24/81 AceView cDNA sequences (see all 81 ):

AI521915 NM_004132 CB162144 AI056527 BX115262 AI373912 BI761782 CB164181

AW771531 BC031412 S83182 N58034 D49742 AW571745 H91171 AW271339

AI522105 N70728 H91225 BX325239 AI242870 BP340909 T68666 AI674836

highest scoring ESTs for HABP2:

D49742 AA484932 AA492062 AA634751 AA677015 AI056527 AI242870 AI373912 AI521915 AI522105

Unigene Cluster for HABP2:

Hyaluronan binding protein 2

Hs.422542 [show with all ESTs]

Unigene Representative Sequence: NM_004132

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000351270

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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HABP2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for HABP2

¹ / ² / ³

3 probe-sets matching HABP2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
742_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	D49742	1.00	1.00	1.00	1
206010_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_004132	0.60	1.00	0.82	1
206010_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks HABP2 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GCTCACAACA

SOURCE GeneReport for Unigene cluster: Hs.422542
Expression variation in blood from EXPOLDB for HABP2
UniProtKB/Swiss-Prot: HABP2_HUMAN, Q14520
Tissue specificity: Ubiquitously expressed

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for HABP2 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	HABP2¹	--	hyaluronan binding protein 2	85.5(n) 82.49(a)	477822 XM_535016.2 XP_535016.2
chimpanzee (Pan troglodytes)	HABP2¹	--	hyaluronan binding protein 2	99.05(n) 98.75(a)	450744 XM_508042.2 XP_508042.2
cow (Bos taurus)	HABP2¹	--	hyaluronan binding protein 2	85.24(n) 81(a)	507993 NM_001014868.1 NP_001014868.1
rat (Rattus norvegicus)	Habp2¹	--	hyaluronan binding protein 2	81.02(n) 79.01(a)	292126 NM_001001505.1 NP_001001505.1
mouse (Mus musculus)	Habp2^{1, 5}	19⁵	hyaluronic acid binding protein 2^{1, 5}	81.93(n)¹ 80.82(a)¹	226243¹ NM_146101.1¹ NP_666213.1¹ AA108229⁵ AA108230⁵ (see all 13)

About this table Species with no ortholog for HABP2

ENSEMBL Gene Tree for HABP2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for HABP2 gene

PLAU² F12² PLAT² HGFAC²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/405 NCBI SNPs in HABP2 are shown (see all 405 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 281)

AB	SNP ID	Valid	Chr 10 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs2240879^1,2	A,C,F,H,O	115302801(-)	`GGGGGA/GAAAAT`	1	--	ut5¹ trp³		22	EA NS NA EU WA	3356
	rs4387289^1,2	A,C,F,H	115301876(+)	`AGTCCG/ACGTGC`	1	--	ng5¹ tfbs³		12	NS EU EA WA	1156
	rs11575688^1,2	C,F,H	115333047(+)	`GGGTGG/CAGAAG`	1	Q/E	mis¹ ese³		10	NS EU EA WA	918
	rs3781391^1,2	A,C,F	115301664(-)	`GCCATC/AAACTC`	1	--	ng5¹		1	EA	1446
	rs7080536^1,2	C,F,H	115338036(+)	`GTGTGG/AGAAGA`	1	E/G	mis¹		9	NS EA WA EU	812
	rs4244308^1,2	C,F,H	115301726(+)	`GAAGTT/CATTTA`	1	--	ng5¹		4	EU EA WA	418
	rs11575750^1,2	C,F,H	115325690(+)	`GCCTCG/ATCCAT`	1	I/V	mis¹ ese³		10	NS EU EA WA	926
	rs2240880^1,2	C,F,H	115302596(-)	`CCTGGC/TTCCAC`	1	--	ng5¹		21	EA NS EU WA	3478
	rs3758589^1,2	C,F,H	115301037(-)	`ATTGCT/GATTTC`	1	--	ng5¹		8	EU EA WA	836
	rs11575621^1,2	F,H	115302458(+)	`TCTATT/AAACAT`	1	--	ng5¹		6	NS EU EA WA	504

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HapMap Linkage Disequilibrium images for HABP2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 603924

10 Novoseek disease relationships for HABP2 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
thromboembolism	51.48	17	16543963 (2), 15486068 (2), 18278202 (1), 16676090 (1) (see all 8)
carotid stenosis	49.91	13	12578864 (2), 18605956 (1), 14977886 (1), 15486068 (1)
pathological processes	16.06	1	15035435 (1)
nsclc	2.11	1	17016581 (1)
breast carcinoma	2.04	1	15690337 (1)
inflammation	0.00	4	1856461 (1), 17483138 (1), 18394684 (1)
tumors	0.00	3	15035435 (1), 16401353 (1)
adenocarcinoma	0.00	2	12386823 (1)
atherosclerosis	0.00	3	18278176 (1)
carcinoma squamous cell	0.00	1	12386823 (1)

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Human Gene Mutation Database: HABP2
Genetic Association Database: HABP2
Human Genome Epidemiology Navigator: HABP2 (5 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/91 PubMed articles for HABP2 gene (see all 91 ):

Purification and characterization of a novel hyaluronan-binding protein (PHBP) from human plasma: it has three EGF, a kringle and a serine protease domain, similar to hepatocyte growth factor activator. (PubMed id 8827452)^{1, 2, 3, 4} Choi-Miura N.-H....Tomita M. (1996)
Factor VII activating protease (FSAP): a novel protease in hemostasis. (PubMed id 12437095)^{1, 2, 3} Romisch J. (2002)
Marburg I polymorphism of factor VII-activating protease is associated with idiopathic venous thromboembolism. (PubMed id 15486068)^{1, 3, 6} Hoppe B....Salama A. (2005)
Marburg I polymorphism of factor VII-activating protease: a prominent risk predictor of carotid stenosis. (PubMed id 12578864)^{1, 3, 4} Willeit J....Roemisch J. (2003)
Identification of the substrates for plasma hyaluronan binding protein. (PubMed id 11217080)^{1, 3, 4} Choi-Miura N.H.... Tomita M. (2001)
The factor VII activating protease G511E (Marburg) variant and cardiovascular risk. (PubMed id 15543324)^{1, 3, 6} Ireland H....Humphries S.E. (2004)
The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)^{3, 4} Deloukas P.... Rogers J. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Factor VII-activating protease in patients with acute deep venous thrombosis. (PubMed id 18394684)^{1, 3} Sidelmann J.J....Jespersen J. (2008)
Extracellular RNA is a natural cofactor for the (auto-)activation of Factor VII-activating protease (FSAP). (PubMed id 15654766)^{1, 3} Nakazawa F....Preissner K.T. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 3026	HGNC: 4798	AceView: HABP2	Ensembl:ENSG00000148702	euGenes: HUgn3026
ECgene: HABP2	H-InvDB: HABP2

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
SeattleSNPs	http://pga.gs.washington.edu/data/habp2/

Licensable Technologies for HABP2
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for HABP2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for HABP2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for HABP2		Antibodies for HABP2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for HABP2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Search Tocris compounds for HABP2

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Antibodies for HABP2

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HABP2 Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for HABP2

Summaries
for HABP2

Genomic Location
for HABP2

Proteins
for HABP2

Protein Domains/
Families
for HABP2

Gene Function
for HABP2

Pathways & Interactions
for HABP2

Drugs & Compounds
for HABP2

Transcripts
for HABP2

Expression
for HABP2

Orthologs
for HABP2

Paralogs
for HABP2

SNPs/Variants
for HABP2

Disorders & Mutations
for HABP2

Medical News
for HABP2

Publications
for HABP2

Search for HABP2

Genome Databases showing HABP2

Other Databases showing HABP2

Specialized Databases showing HABP2

Licensable Technologies
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Services
for HABP2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

HABP2 Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor HABP2

Summariesfor HABP2

Genomic Locationfor HABP2

Proteinsfor HABP2

Protein Domains/Familiesfor HABP2

Gene Functionfor HABP2

Pathways & Interactionsfor HABP2

Drugs & Compoundsfor HABP2

Transcriptsfor HABP2

Expression for HABP2

Orthologsfor HABP2

Paralogsfor HABP2

SNPs/Variantsfor HABP2

Disorders & Mutationsfor HABP2

Medical Newsfor HABP2

Publicationsfor HABP2

Search for HABP2

Genome Databases showing HABP2

Other Databases showing HABP2

Specialized Databases showing HABP2

Licensable Technologiesfor HABP2

Servicesfor HABP2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for HABP2

Summaries
for HABP2

Genomic Location
for HABP2

Proteins
for HABP2

Protein Domains/
Families
for HABP2

Gene Function
for HABP2

Pathways & Interactions
for HABP2

Drugs & Compounds
for HABP2

Transcripts
for HABP2

Expression
for HABP2

Orthologs
for HABP2

Paralogs
for HABP2

SNPs/Variants
for HABP2

Disorders & Mutations
for HABP2

Medical News
for HABP2

Publications
for HABP2

Licensable Technologies
for HABP2

Services
for HABP2