HAAO Gene
protein-coding GIFtS: 62
GCID: GC02M042994
|
|
3-hydroxyanthranilate 3,4-dioxygenase
| |
Aliases
for HAAO gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| 3-Hydroxyanthranilate 3,4-Dioxygenase1 2 | | HAD2 3 | | 3-HAO2 3 | | EC 1.13.11.63 8 | | 3-Hydroxyanthranilate Oxygenase2 3 | | HAO2 | | 3-Hydroxyanthranilic Acid Dioxygenase2 3 | | |
Export aliases for HAAO gene to outside databasesPrevious GC identifers: GC02M042982 GC02M043162 GC02M042968 GC02M042905 GC02M042847 GC02M042728 |
Summaries
for HAAO gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HAAO:
3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramoleculardioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney,and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid(QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activateglutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis ofneurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with alteredtissue levels of QUIN. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: 3HAO_HUMAN, P46952Function: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde,which spontaneously cyclizes to quinolinate
|
Genomic Views
for HAAO gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HAAO gene promoter:
PPAR-gamma1 HTF FOXD3 SEF-1 (1) PPAR-gamma2 Pax-4a E4BP4 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for HAAO
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HAAO |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p21 Ensembl cytogenetic band: 2p21 HGNC cytogenetic band: 2pHAAO Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M042994: view genomic region
(about GC identifiers)
Start:
|
42,994,229 bp from pter |
End:
|
43,019,751 bp from pter |
Size:
|
25,523 bases |
Orientation:
|
minus strand |
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Proteins
for HAAO gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: 3HAO_HUMAN, P46952 (See
protein sequence)Recommended Name: 3-hydroxyanthranilate 3,4-dioxygenase Size: 286 amino acids; 32556 Da
Cofactor: Fe(2+) ion
Subunit: Monomer
Subcellular location: Cytoplasm
1 PDB 3D structure from  and Proteopedia  for HAAO:2QNK (3D)
Secondary accessions: A6NE56 B4DIN2 Q53QZ7 Q8N6N9Alternative splicing: 2 isoforms: P46952-1 P46952-2 Explore the universe of human proteins at neXtProt for HAAO: NX_P46952
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P46952
3 DME Specific Peptides for HAAO (P46952)
HAAO Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_036337.2
ENSEMBL proteins: ENSP00000294973 ENSP00000412601 Reactome Protein details: P46952
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
HAAO for ontologies About GeneDecksing
HAAO Antibody Products:
Assay Products for HAAO: |
Protein
Domains /
Families
for HAAO gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HAAO for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P46952ProtoNet protein and cluster: P46952 UniProtKB/Swiss-Prot: 3HAO_HUMAN, P46952Similarity: Belongs to the 3-HAO family |
Function
for HAAO gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: 3HAO_HUMAN, P46952Function: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde,which spontaneously cyclizes to quinolinateCatalytic activity: 3-hydroxyanthranilate + O(2) = 2-amino-3-carboxymuconate semialdehydeEnzyme Number (IUBMB): EC 1.13.11.61 2
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HAAO
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for HAAO | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAAO |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAAO |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
HAAO for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for HAAO:
|
Pathways & Interactions
for HAAO gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde | | | 2 | Metabolism | | | 3 | NAD metabolism | | | 4 | Tryptophan metabolism | | | 5 | Metabolism of amino acids and derivatives | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for HAAO
1  GeneGo (Thomson Reuters) Pathway for HAAO
4  BioSystems Pathways for HAAO
3 
Reactome Pathways for HAAO
2 
Kegg Pathways (Kegg details for HAAO):
UniProtKB/Swiss-Prot: 3HAO_HUMAN, P46952Pathway: Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3
HAAO for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HAAO
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/35 Interacting proteins for HAAO (P469522, 3 ENSP000002949734) via UniProtKB, MINT, STRING, and/or I2D (see all 35)
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
HAAO for ontologies About GeneDecksing
|
Drugs & Compounds
for HAAO gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
HAAO for compounds About GeneDecksing
 Browse Tocris compounds for HAAO
4 HMDB Compounds for HAAO About this table
7 Novoseek chemical compound relationships for HAAO gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| 3-hydroxyanthranilic acid |
95 |
24 |
9539135 (4), 16522801 (3), 12007609 (2), 7514594 (2) (see all 10) |
| quinolinic acid |
80 |
7 |
12007609 (2), 1825460 (2), 9685612 (1), 1831362 (1) (see all 5) |
| kynurenine |
74.2 |
4 |
16522801 (1), 8906308 (1), 9539135 (1) |
| hydroxylamine |
71.7 |
6 |
15697211 (1), 18761666 (1), 18973625 (1), 2338066 (1) (see all 5) |
| quinine |
62.8 |
6 |
9685612 (1), 7514594 (1) |
| hydrazine |
50 |
3 |
18761666 (1), 18973625 (1) |
| polyacrylamide |
25.1 |
1 |
2338066 (1) |
Search CenterWatch for drugs/clinical trials and news about HAAO / 3HAO
|
Transcripts
for HAAO gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HAAO gene: NM_012205.2 Unigene Cluster for HAAO: 3-hydroxyanthranilate 3,4-dioxygenase Hs.368805 [show with all ESTs]Unigene Representative Sequence: NM_0122057 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000406007 ENST00000294973(uc002rst.4) ENST00000402698 ENST00000404451
ENST00000431905 ENST00000406924(uc010ynw.1) ENST00000402268
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HAAO (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HAAO
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HAAO (NM_012205) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HAAO | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAAO |
Additional cDNA sequence: AK295693.1 BC029510.1 CR457063.1 Z29481.1 5 DOTS entries: DT.212090 DT.102823242 DT.99976662 DT.100751508 DT.95159385 24/51 AceView cDNA sequences (see all 51): CR624693 CB850657 AW615072 BI908552 BU859616 BI602406 CR457063 AI354294 AI341625 BI768871 BU732656 BX105135 AL554133 NM_012205 BQ719546 BF514377 BC029510 BM906893 Z29481 AI005031 R78903 CB994232 AV686771 T80846
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for HAAO About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 |
|---|
|
| SP1: | | | | | | | - | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | - | | - | | - | | | | - | | - | | | | | | | | | | |
| SP4: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for HAAO
|
Expression
for HAAO gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HAAO expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCCTGGGCG
About this image
See HAAO Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HAAO
SOURCE GeneReport for Unigene cluster: Hs.368805
SABiosciences Expression via Pathway-Focused PCR Arrays including HAAO:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HAAO
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HAAO | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAAO | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAAO | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAAO |
Orthologs
for HAAO gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals and fungi.
Orthologs for HAAO gene from 7/20 species (see all 20) About this table
ENSEMBL Gene Tree for HAAO (if available)
TreeFam Gene Tree for HAAO (if available) |
Paralogs
for HAAO gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for HAAO gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HAAO (42994229 - 43019751 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for HAAO
1 CNV: 9406 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HAAO |
|
Disorders
/ Diseases
for HAAO gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HAAO for disorders About GeneDecksing
OMIM gene information: 604521
OMIM disorders: --
13  diseases for HAAO: About MalaCardscerebritis transient cerebral ischemia olivopontocerebellar atrophy pellagra
conduct disorder multiple sclerosis huntington's disease endometrial carcinoma
parkinson's disease ovarian cancer ischemia carcinoma
neuronitis
1 disease from the University of Copenhagen DISEASES database for HAAO:Pellagra Human Genome Epidemiology (HuGE) Navigator: HAAO (3 documents)
Export disorders for HAAO gene to outside databases
|
Publications
for HAAO gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HAAO gene, integrated from 9 sources (see all 35):
(articles sorted by number of sources associating them with HAAO) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and functional expression of human 3- hydroxyanthranilic-acid dioxygenase. (PubMed id 7514594)1, 2, 3, 9 Malherbe P.... Cesura A.M. (1994)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+. (PubMed id 12007609)1, 9 Calderone V....Zanotti G. (2002)
- Identification of candidate epigenetic biomarkers for ovarian cancer detection. (PubMed id 19724865)1, 9 Huang Y.W....Lin H.J. (2009)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
- Evidence for genes on chromosome 2 contributing to al cohol dependence with conduct disorder and suicide attempts. (PubMed id 20468071)1 Dick D.M....Bierut L. (2010)
- Promoter hypermethylation of CIDEA, HAAO and RXFP3 as sociated with microsatellite instability in endometrial carcinomas. (PubMed id 20211485)1 Huang Y.W....Huang T.H. (2010)
- Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1 Trynka G....Wijmenga C. (2009)
|
External Searches for HAAO gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HAAO gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HAAO gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HAAO gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HAAO | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HAAO gene:
Search GeneIP for patents involving HAAO
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HAAO gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for HAAO | | OriGene shRNA RFP for HAAO | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HAAO | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HAAO | | | OriGene Protein Over-expression Lysate for HAAO | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HAAO | | OriGene 3'-UTR Clone for HAAO | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HAAO | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HAAO | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for HAAO | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HAAO | | OriGene Custom Protein Services for HAAO | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HAAO | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HAAO | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HAAO | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HAAO | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HAAO | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HAAO |
| |
 |  |  |  | |
| | | | Search Tocris compounds for HAAO |
| |  |  |  |  | | | | | | Recombinant Protein for HAAO |
|
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 |
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 | | | HAAO Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HAAO |
|  |  |  | | | | ThermoFisher Antibodies for HAAO |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HAAO |
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