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HAAO Gene

protein-coding GIFtS: 57

GC02M042847

3-hydroxyanthranilate 3,4-dioxygenase
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
3-HAO ^², ³
EC 1.13.11.6 ^³
HAD ^³
HAO ^²

Descriptions
3-hydroxyanthranilate 3,4-dioxygenase ^²
3-hydroxyanthranilate oxygenase ^², ³
3-hydroxyanthranilic acid dioxygenase ^², ³

External Ids
HGNC: 4796¹
Entrez Gene: 23498²
UniProtKB: P46952³
Ensembl: ENSG00000162882⁷

Search outside databases for aliases for HAAO gene

Previous GC identifers: GC02M042982 GC02M043162 GC02M042968 GC02M042905

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for HAAO:

3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of

intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in

peripheral organs, such as liver and kidney, and is also present in low amounts in the central

nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic

acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate

N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the

pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in

disorders associated with altered tissue levels of QUIN. [provided by RefSeq]

UniProtKB/Swiss-Prot: 3HAO_HUMAN, P46952

Function: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to

2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the HAAO gene

Entrez Gene cytogenetic band: 2p21 Ensembl cytogenetic band: 2p21 HGNC cytogenetic band: 2p

HAAO Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M042847: (about GC identifiers)

Start:	42,847,138 bp from pter
End:	42,873,245 bp from pter
Size:	26,108 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000002.10 NT_022184.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: 3HAO_HUMAN, P46952 (See protein sequence)

Recommended Name: 3-hydroxyanthranilate 3,4-dioxygenase

Size: 286 amino acids; 32542 Da

Cofactor: Fe(2+) ion

Subunit: Monomer

Subcellular location: Cytoplasm

PDB structures from and Proteopedia :

2QNK (3D)

Secondary accessions: A6NE56 B4DIN2 Q53QZ7 Q8N6N9

Alternative splicing: 2 isoforms: P46952-1 P46952-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_036337.2

ENSEMBL proteins:

ENSP00000384778 ENSP00000384314 ENSP00000384961 ENSP00000385670 ENSP00000385224 ENSP00000385459

ENSP00000294973

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (HAAO)
	Human Recombinant Proteins from Abnova (HAAO)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005625	soluble fraction	IDA	12007609
GO:0005737	cytoplasm	IEA	--
GO:0005829	cytosol	IDA	7514594

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Antibodies for HAAO:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (HAAO), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (HAAO)
	Novus Biologicals Antibody for HAAO

Assays for HAAO:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P46952

ProtoNet protein and cluster: P46952

UniProtKB/Swiss-Prot: 3HAO_HUMAN, P46952

Similarity: Belongs to the 3-HAO family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HAAO)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (HAAO)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012205

Applied Biosystems Silencer® siRNAs for HAAO

Sigma-Aldrich siRNA for HAAO

Sigma-Aldrich shRNA for HAAO

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for HAAO
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_012205
Myc/DDK tagged cDNA clone in CMV expression vector: NM_012205
untagged cDNA clone in CMV expression vector: NM_012205

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_012205

UniProtKB/Swiss-Prot: 3HAO_HUMAN, P46952

Function: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to

2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate

Catalytic activity: 3-hydroxyanthranilate + O(2) = 2-amino-3-carboxymuconate semialdehyde

Enzyme Number (IUBMB): EC 1.13.11.6

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000334	3-hydroxyanthranilate 3,4-dioxygenase activity	IDA	7514594 12007609
GO:0008198	ferrous iron binding	IDA	12007609
GO:0009055	electron carrier activity	NAS	7514594
GO:0016491	oxidoreductase activity	IEA	--
GO:0046872	metal ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for HAAO (Your Favorite Gene powered by Ingenuity)

Tryptophan Metabolism

GeneDecks HAAO for the pathways selected above

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UniProtKB/Swiss-Prot: 3HAO_HUMAN, P46952

Pathway: Cofactor biosynthesis; NAD(+) biosynthesis; pyridine-2,3-dicarboxylate from L-kynurenine:

step 3/3

1 Interacting protein for HAAO (P46952²) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
--	Q8IVA8²	MINT-66322

About this table
5/7 Gene Ontology (GO) biological process terms (links to tree view) (see all 7 ):
GO ID Qualified GO term Evidence PubMed IDs
GO:0010043 response to zinc ion IDA 12007609
GO:0019363 pyridine nucleotide biosynthetic process IEA --
GO:0019674 NAD metabolic process EXP 14704851
GO:0019805 quinolinate biosynthetic process NAS 7514594 12007609
GO:0046686 response to cadmium ion IDA 12007609
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for HAAO
4 Novoseek chemical compound relationships for HAAO gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
quinolinic acid	80.75	7	12007609 (2), 1825460 (2), 9685612 (1), 1831362 (1) (see all 5)
kynurenine	75.35	4	16522801 (1), 8906308 (1), 9539135 (1)
hydroxylamine	72.63	6	15697211 (1), 18761666 (1), 18973625 (1), 2338066 (1) (see all 5)
polyacrylamide	26.55	1	2338066 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (HAAO)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (HAAO)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012205

Sigma-Aldrich siRNA for HAAO

Sigma-Aldrich shRNA for HAAO

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_012205

REFSEQ mRNAs for HAAO gene:

NM_012205.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_012205

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_012205
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_012205
                                 untagged cDNA clone in CMV expression vector: NM_012205

Additional cDNA sequence:

AK295693.1 BC029510.1 CR457063.1 CR624693.1 Z29481.1

5 DOTS entries:

DT.212090 DT.102823242 DT.100751508 DT.99976662 DT.95159385

24/51 AceView cDNA sequences (see all 51 ):

CB850657 CR624693 AW615072 AI341625 BI908552 AL554133 BC029510 BQ719546

AI354294 BI602406 BI768871 BX105135 Z29481 CR457063 AI005031 BM906893

BU732656 BU859616 BF514377 NM_012205 CD675091 AU098729 AV686771 R79003

highest scoring ESTs for HAAO:

Z29481 AU098729 BC029510 BI602406 BU859616 CB994232 CR457063 AI912751 AL554133 AV657701

Unigene Cluster for HAAO:

3-hydroxyanthranilate 3,4-dioxygenase

Hs.368805 [show with all ESTs]

Unigene Representative Sequence: CR624693

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for HAAO

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4	^	5a	·	5b	^	6a	·	6b	^	7	^	8a	·	8b	^	9	^	10a	·	10b	^	11
SP1:							-								-				-
SP2:															-				-
SP3:							-								-		-		-				-		-
SP4:							-
SP5:															-

About this scheme

ECgene alternative splicing isoforms for HAAO

7 Ensembl transcripts including schematic representations:

ENST00000406007 ENST00000404451 ENST00000402698 ENST00000406924 ENST00000402268 ENST00000405814

ENST00000294973

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

HAAO expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for HAAO

¹ / ² / ³

4 probe-sets matching HAAO gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
37166_at²^{, 3}	U95-A	2	1.00	0.97	0.98	0.94	Z29481	1.00	1.00	1.00	1
48794_s_at²^{, 3}	U95-B	2	1.00	0.97	0.98	1.06	AW001298	0.60	1.00	0.82	1
205657_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_012205	0.60	1.00	0.82	1
205657_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks HAAO for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CCCCTGGGCG

SOURCE GeneReport for Unigene cluster: Hs.368805
Expression variation in blood from EXPOLDB for HAAO

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for HAAO gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	HAAO¹	--	3-hydroxyanthranilate 3,4-dioxygenase	87.39(n) 85.71(a)	611728 XM_849433.1 XP_854526.1
cow (Bos taurus)	HAAO¹	--	3-hydroxyanthranilate 3,4-dioxygenase	90.09(n) 86.71(a)	510602 NM_001075458.1 NP_001068926.1
rat (Rattus norvegicus)	Haao¹	--	3-hydroxyanthranilate 3,4-dioxygenase	86.71(n) 87.41(a)	56823 NM_020076.1 NP_064461.1
mouse (Mus musculus)	Haao^{1, 5}	17⁵	3-hydroxyanthranilate 3,4-dioxygenase^{1, 5}	85.45(n)¹ 86.27(a)¹	107766¹ NM_025325.2¹ NP_079601.1¹ AI526920⁵ AK002295⁵ (see all 10)
chicken (Gallus gallus)	HAAO¹	--	3-hydroxyanthranilate 3,4-dioxygenase	58.8(n) 59.86(a)	421396 XM_419453.2 XP_419453.2

About this table Species with no ortholog for HAAO

ENSEMBL Gene Tree for HAAO

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/243 NCBI SNPs in HAAO are shown (see all 243 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 108)

AB	SNP ID	Valid	Chr 2 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs2304656^1,2	A,C,F,H	42873234(+)	`CCCGCG/AGCTCC`	1	--	ut5¹ ese³		5	EA EU WA	1328
	rs4952937^1,2	A,C,F,H	42873312(+)	`GGGGGC/ATTGGG`	1	--	ng3¹		4	EU EA WA	368
	rs6724265^1,2	A,C,F,H	42873740(+)	`GCTGCC/GGCGCT`	1	--	ng3¹		2	EA WA	326
	rs3816183^1,2	A,C,F,H	42869223(+)	`TCCGAC/TGAACA`	1	I/V	mis¹ ese³		17	EA NA EU WA	1544
	rs1065643^1,2	A,C,F,H	42874697(-)	`AGCAAA/GCTTAA`	1	--	ng3¹		10	EA NA EU WA	1950
	rs2278581^1,2	A,C,F,H	42874418(+)	`CTAGTG/ACAACT`	1	--	ng3¹		12	EA NA EU WA	2400
	rs2304659^1,2	C,F,H	42847873(+)	`GTCTGC/TCAGAG`	1	--	ut3¹ ese³		8	EA NA EU WA	2044
	rs3816182^1,2	C,F,H	42869208(+)	`CCTGGT/AGTTGG`	1	S/T	mis¹ ese³		9	EU EA WA NA	902
	rs2304661^1,2	C,F,H	42847988(+)	`ACACAG/TAGAGG`	1	--	ut3¹		12	EA NA EU WA	2478
	rs17630329^1,2	C,F,H	42847975(+)	`ACACAG/TCGGCA`	1	--	ut3¹ ese³		11	NA EU EA WA	980

About this table

HapMap Linkage Disequilibrium images for HAAO (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 604521

Human Genome Epidemiology Navigator: HAAO (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/30 PubMed articles for HAAO gene (see all 30 ):

Molecular cloning and functional expression of human 3- hydroxyanthranilic-acid dioxygenase. (PubMed id 7514594)^{1, 2, 3, 4} Malherbe P.... Cesura A.M. (1994)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)^{3, 4} Hillier L.W....Wilson R.K. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+. (PubMed id 12007609)^{1, 3} Calderone V....Zanotti G. (2002)
Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)³ Trynka G....Wijmenga C. (2009)
Identification of genes related to Parkinson's disease using expressed sequence tags. (PubMed id 17213182)³ Kim J.M....Kim N.S. (2006)
Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)³ Rual J.F....Vidal M. (2005)
Enzymology of NAD+ homeostasis in man. (PubMed id 14704851)³ Magni G....Ruggieri S. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)⁴ Ota T....Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 23498	HGNC: 4796	AceView: HAAO	Ensembl:ENSG00000162882	euGenes: HUgn23498
ECgene: HAAO	H-InvDB: HAAO

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for HAAO
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for HAAO:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for HAAO-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for HAAO		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for HAAO		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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HAAO Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for HAAO

Summaries
for HAAO

Genomic Location
for HAAO

Proteins
for HAAO

Protein Domains/
Families
for HAAO

Gene Function
for HAAO

Pathways & Interactions
for HAAO

Drugs & Compounds
for HAAO

Transcripts
for HAAO

Expression
for HAAO

Orthologs
for HAAO

Paralogs
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SNPs/Variants
for HAAO

Disorders & Mutations
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Medical News
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Publications
for HAAO

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Genome Databases showing HAAO

Other Databases showing HAAO

Specialized Databases showing HAAO

Licensable Technologies
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Services
for HAAO

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

HAAO Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor HAAO

Summariesfor HAAO

Genomic Locationfor HAAO

Proteinsfor HAAO

Protein Domains/Familiesfor HAAO

Gene Functionfor HAAO

Pathways & Interactionsfor HAAO

Drugs & Compoundsfor HAAO

Transcriptsfor HAAO

Expression for HAAO

Orthologsfor HAAO

Paralogsfor HAAO

SNPs/Variantsfor HAAO

Disorders & Mutationsfor HAAO

Medical Newsfor HAAO

Publicationsfor HAAO

Search for HAAO

Genome Databases showing HAAO

Other Databases showing HAAO

Specialized Databases showing HAAO

Licensable Technologiesfor HAAO

Servicesfor HAAO

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for HAAO

Summaries
for HAAO

Genomic Location
for HAAO

Proteins
for HAAO

Protein Domains/
Families
for HAAO

Gene Function
for HAAO

Pathways & Interactions
for HAAO

Drugs & Compounds
for HAAO

Transcripts
for HAAO

Expression
for HAAO

Orthologs
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