H6PD Gene
protein-coding GIFtS: 56
GCID: GC01P009294
|
|
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)(Previous name: glucose dehyrogenase )
(Previous symbol: GDH)
| |
Aliases
for H6PD gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Hexose-6-Phosphate Dehydrogenase (Glucose 1-Dehydrogenase)1 2 | | GDH/6PGL Endoplasmic Bifunctional Protein2 | | GDH1 2 3 5 | | Glucose 1- Dehydrogenase2 | | Glucose Dehyrogenase1 2 | | Glucose Dehydrogenase2 | | G6PDH2 5 | | Glucose-6-Phosphate Dehydrogenase, Salivary2 | | 6-Phosphogluconolactonase1 | | EC 1.1.1.498 | | CORTRD12 | | EC 2.7.4.38 | | G6PD, H Form2 | | EC 3.1.1.318 |
Export aliases for H6PD gene to outside databasesPrevious GC identifers: GC01P008915 GC01P009105 GC01P009004 GC01P009229 GC01P008445 |
Summaries
for H6PD gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for H6PD:
There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, isautosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate,whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is notfound in red cells. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: G6PE_HUMAN, O95479Function: Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates
Gene Wiki entry for H6PD
|
Genomic Views
for H6PD gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_021937.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the H6PD gene promoter:
ER-alpha Spz1 NF-1 GCNF RORalpha2 Max GCNF-1 Ik-1 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for H6PD
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat H6PD |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36 Ensembl cytogenetic band: 1p36.22 HGNC cytogenetic band: 1p36H6PD Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P009294: view genomic region
(about GC identifiers)
Start:
|
9,294,863 bp from pter |
End:
|
9,331,396 bp from pter |
Size:
|
36,534 bases |
Orientation:
|
plus strand |
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Proteins
for H6PD gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: G6PE_HUMAN, O95479 (See
protein sequence)Recommended Name: GDH/6PGL endoplasmic bifunctional protein precursor Size: 791 amino acids; 88893 Da
Subcellular location: Endoplasmic reticulum lumen. Note=Microsomes, endoplasmic reticulum lumen
Sequence caution: Sequence=CAH18137.1; Type=Erroneous initiation;
Secondary accessions: Q4TT33 Q66I35 Q68DT3Explore the universe of human proteins at neXtProt for H6PD: NX_O95479
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O95479
3 DME Specific Peptides for H6PD (O95479)
H6PD Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004276.2
ENSEMBL proteins: ENSP00000366620
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
H6PD for ontologies About GeneDecksing
H6PD Antibody Products:
Assay Products for H6PD: |
Protein
Domains /
Families
for H6PD gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
H6PD for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry O95479ProtoNet protein and cluster: O95479 UniProtKB/Swiss-Prot: G6PE_HUMAN, O95479Similarity: In the N-terminal section; belongs to the glucose-6-phosphate dehydrogenase familySimilarity: In the C-terminal section; belongs to the glucosamine/galactosamine-6-phosphate isomerase family.6-phosphogluconolactonase subfamily |
Function
for H6PD gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: G6PE_HUMAN, O95479Function: Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphatesCatalytic activity: Beta-D-glucose + NAD(P)(+) = D-glucono-1,5-lactone + NAD(P)HCatalytic activity: D-glucose 6-phosphate + NAD(P)(+) = D-glucono-1,5-lactone 6-phosphate + NAD(P)HCatalytic activity: 6-phospho-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconateEnzyme Numbers (IUBMB): EC 2.7.4.32 EC 3.1.1.312 EC 1.1.1.492
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for H6PD (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for H6PD
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: H6PD (NM_004285) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for H6PD | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat H6PD |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for H6PD |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004345 | glucose-6-phosphate dehydrogenase activity |
IEA | -- | | GO:0017057 | 6-phosphogluconolactonase activity |
IEA | -- | | GO:0030246 | carbohydrate binding |
IEA | -- | | GO:0047936 | glucose 1-dehydrogenase [NAD(P)] activity |
IEA | -- | | GO:0050661 | NADP binding |
IEA | -- |
H6PD for ontologies About GeneDecksing
Animal Models:
Mouse knock-out H6pdtm1Pmst for H6PD
6 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for H6pd):
H6PD for phenotypes About GeneDecksing
|
Pathways & Interactions
for H6PD gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Pentose phosphate pathway | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Kegg Pathways (Kegg details for H6PD):
H6PD for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for H6PD
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
4 Interacting proteins for H6PD (ENSP000003666204) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
H6PD for ontologies About GeneDecksing
|
Drugs & Compounds
for H6PD gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
H6PD for compounds About GeneDecksing
 Browse Tocris compounds for H6PD
10 HMDB Compounds for H6PD About this table
1 DrugBank Compound for H6PD About this table
10/93 Novoseek chemical compound relationships for H6PD gene (see all 93) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| glucose 6-phosphate |
92.9 |
193 |
7781912 (2), 9392523 (2), 17137780 (2), 19804362 (2) (see all 99) |
| 11beta-hydroxysteroid |
86.2 |
35 |
18622204 (4), 18381077 (2), 18963204 (2), 19010388 (2) (see all 22) |
| pyrroloquinoline quinone |
85.9 |
21 |
16131222 (2), 10933491 (1), 11225357 (1), 9670773 (1) (see all 11) |
| o-ethylhydroxylamine |
80.2 |
1 |
10087986 (1) |
| cortisone |
78.6 |
16 |
15956339 (1), 17062770 (1), 16091483 (1), 17240046 (1) (see all 12) |
| no-dimethylhydroxylamine |
78.4 |
2 |
9137808 (1) |
| neotetrazolium |
76.9 |
5 |
7930518 (3), 9306960 (1) |
| 6-phosphogluconate |
76.8 |
16 |
8470806 (1), 11072071 (1), 20127344 (1), 1381200 (1) (see all 13) |
| nadph |
74 |
52 |
12858176 (2), 10329961 (2), 17303087 (2), 19804362 (2) (see all 39) |
| glucose |
68.7 |
285 |
17365439 (5), 8082531 (4), 16556607 (4), 7764620 (3) (see all 99) |
Search CenterWatch for drugs/clinical trials and news about H6PD / G6PE
|
Transcripts
for H6PD gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for H6PD gene: NM_004285.3 Unigene Cluster for H6PD: Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) Hs.463511 [show with all ESTs]Unigene Representative Sequence: NM_0042852 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000377403(uc001apt.3) ENST00000495451
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for H6PD (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for H6PD
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: H6PD (NM_004285) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for H6PD | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat H6PD |
Additional cDNA sequence: AJ012590.1 AK024548.1 AK026460.1 AK091191.1 AL832271.1 AL833024.1 AY142148.1 BC007368.2 BC026099.1 BC044256.1 BC069028.1 BC081559.1 BC098450.1 CR749282.1 11 DOTS entries: DT.40133057 DT.439862 DT.92418967 DT.100783194 DT.121337152 DT.121337183 DT.86846264 DT.100786227 DT.121496200 DT.452870 DT.99974386 24/161 AceView cDNA sequences (see all 161): CB989699 BC044256 CK902392 AJ012590 AK024548 AL602889 AI867461 AI264583 AI744639 BQ706722 BU071074 CD367658 BU070635 NM_004285 BF744875 AA609834 AL707973 AI362636 CA420503 BQ675151 BQ671499 BU429746 BQ436379 BX474493
GeneLoc Exon Structure
|
Expression
for H6PD gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| H6PD expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTGGCCAGA
About this image
See H6PD Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for H6PD
SOURCE GeneReport for Unigene cluster: Hs.463511
UniProtKB/Swiss-Prot: G6PE_HUMAN, O95479Tissue specificity: Present in most tissues examined, strongest in liver
SABiosciences Expression via Pathway-Focused PCR Array including H6PD:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for H6PD
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat H6PD | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat H6PD | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat H6PD | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for H6PD |
Orthologs
for H6PD gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for H6PD gene from 5/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
H6PD1 |
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
70.61(n)
69.85(a) |
|
428188 XM_425746.3 XP_425746.3 |
lizard
(Anolis carolinensis) |
Reptilia |
H6PD6 |
-- |
61(a) |
1 ↔ 1 |
GL343701.1(142546-157483) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.301862 |
Xenopus laevis transcribed sequence with weak similarity more |
71.46(n) |
|
48022608 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC5693481 |
GDH/6PGL endoplasmic bifunctional protein-like |
56.44(n)
53.84(a) |
|
569348 XM_692728.4 XP_697820.3 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
zwf6 |
glucose-6-phosphate 1-dehydrogenase |
25(a) |
1 → many |
Chromosome(1932863-1934338) |
ENSEMBL Gene Tree for H6PD (if available)
TreeFam Gene Tree for H6PD (if available) |
Paralogs
for H6PD gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for H6PD gene
- G6PD2
H6PD for paralogs About GeneDecksing
|
Genomic Variants
for H6PD gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for H6PD (9294863 - 9331396 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for H6PD
6 CNVs: 48377 53758 71924 8317 8316 48378
Human Gene Mutation Database (HGMD): H6PD
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing H6PD |
|
Disorders
/ Diseases
for H6PD gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
H6PD for disorders About GeneDecksing
OMIM gene information: 138090
OMIM disorders: 604931
UniProtKB/Swiss-Prot: G6PE_HUMAN, O95479
Defects in H6PD are a cause of cortisone reductase deficiency (CRD) [MIM:604931]. In CRD, activation ofcortisone to cortisol does not occur, resulting in adrenocorticotropin-mediated androgen excess and a phenotyperesembling polycystic ovary syndrome (PCOS)
20/53  diseases for H6PD (see all 53): About MalaCardscortisone reductase deficiency protein-energy malnutrition polycystic ovary syndrome nonalcoholic steatohepatitis
non-hodgkin lymphoma type 2 diabetes mellitus diabetes mellitus amyotrophic lateral sclerosis
insulin resistance lateral sclerosis parotitis hodgkin's lymphoma
lymphosarcoma neuromuscular disease renal cell carcinoma cystic fibrosis
hyperglycemia gastric ulcer pulmonary tuberculosis down syndrome
10/31 Novoseek disease relationships for H6PD gene (see all 31) About this table
Genetic Association Database (GAD): H6PD
Human Genome Epidemiology (HuGE) Navigator: H6PD (7 documents)
Export disorders for H6PD gene to outside databases
|
Publications
for H6PD gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for H6PD gene, integrated from 9 sources (see all 348):
(articles sorted by number of sources associating them with H6PD) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) encoded at 1p36: coding sequence and expression. (PubMed id 10349511)1, 2, 3, 9 Mason P.J....Vulliamy T.J. (1999)
- Genotypes at 11beta-hydroxysteroid dehydrogenase type 11B1 and hexose-6-phosphate dehydrogenase loci are not risk factors for apparent cortisone reductase deficiency in a large population-based sample. (PubMed id 16091483)1, 4, 9 White P.C. (2005)
- Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. (PubMed id 12858176)1, 2, 9 Draper N....Stewart P.M. (2003)
- A study of the hexose-6-phosphate dehydrogenase gene R453Q and 11beta-hydroxysteroid dehydrogenase type 1 gene 83557insA polymorphisms in the polycystic ovary syndrome. (PubMed id 15827106)1, 4, 9 San Millan J.L....Escobar-Morreale H.F. (2005)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Constant expression of hexose-6-phosphate dehydrogenase during differentiation of human adipose-derived mesenchymal stem cells. (PubMed id 18586838)1, 9 Senesi S....Benedetti A. (2008)
- Exposure to chrysotile asbestos causes carbonylation of glucose 6-phosphate dehydrogenase through a reaction with lipid peroxidation products in human lung epithelial cells. (PubMed id 20211231)1, 9 Ogasawara Y. and Ishii K. (2010)
- Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis. (PubMed id 19935835)1, 9 Alcina A....Matesanz F. (2010)
- Adipose tissue 11-beta-Hydroxysteroid Dehydrogenase Type 1 and Hexose-6-Phosphate Dehydrogenase gene expressions are increased in patients with type 2 diabetes mellitus. (PubMed id 18963204)1, 9 UAskaya G....Kutlu M. (2008)
|
External Searches for H6PD gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing H6PD gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing H6PD gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing H6PD gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for H6PD | Pharmacogenomics, SNPs, Pathways | | ATLAS Chromosomes in Cancer entry for H6PD | Genetics and Cytogenetics in Oncology and Haematology | | SHMPD | http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=H6PD |
|
| | |
About This Section
| Patent Information for H6PD gene:
Search GeneIP for patents involving H6PD
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for H6PD gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for H6PD | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for H6PD | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for H6PD | | | OriGene Protein Over-expression Lysate for H6PD | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for H6PD | | OriGene 3'-UTR Clone for H6PD | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for H6PD | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for H6PD | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for H6PD | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for H6PD | | OriGene Custom Protein Services for H6PD | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat H6PD | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing H6PD | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat H6PD | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat H6PD | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat H6PD | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat H6PD |
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| | | | Search Tocris compounds for H6PD |
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 | | | H6PD Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for H6PD |
|  |  |  | | | | ThermoFisher Antibodies for H6PD |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat H6PD |
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