Aliases for H2BFS Gene
External Ids for H2BFS Gene
GeneCards Summary for H2BFS Gene
H2BFS (H2B Histone Family, Member S (Pseudogene)) is a Pseudogene. Among its related pathways are Disease and Cell Cycle, Mitotic. GO annotations related to this gene include protein heterodimerization activity.
UniProtKB/Swiss-Prot for H2BFS Gene
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid