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Aliases &
Descriptions
for H2BFM
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| | | Descriptions |
|---|
| H2B histone family, member M 2 |
|
| |
Search outside databases for aliases for H2BFM genePrevious GC identifer: GC0XP103098 |
Summaries
for H2BFM(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: H2BFM_HUMAN, P0C1H6Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting
DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby
play a central role in transcription regulation, DNA repair, DNA replication and chromosomal
stability. DNA accessibility is regulated via a complex set of post-translational modifications of
histones, also called histone code, and nucleosome remodeling |
Genomic Location
for H2BFM
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the H2BFM gene 
Entrez Gene cytogenetic band: Xq22.2 Ensembl cytogenetic band: Xq22.2 HGNC cytogenetic band: Xq22.2H2BFM Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP103177:
(about GC identifiers)
Start:
|
103,154,925 bp from pter |
End:
|
103,183,677 bp from pter |
Size:
|
28,753 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000023.9 NT_011651.16
| Proteins
for H2BFM
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: H2BFM_HUMAN, P0C1H6 (See
protein sequence)Recommended Name: Histone H2B type F-M Size: 257 amino acids; 28267 Da
Subunit: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4
assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps
approximately 147 bp of DNA
Subcellular location: Nucleus
Miscellaneous: In contrast to other H2B histones, it does not contain the conserved residue in
C-terminus that is the target of monoubiquitination
Secondary accessions: A6NP82
ENSEMBL proteins: ENSP00000347119 ENSP00000243297
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells
3 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for H2BFM:
Assays for H2BFM: | Protein
Domains/
Families
for H2BFM(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry P0C1H6
ProtoNet protein and cluster: P0C1H6 UniProtKB/Swiss-Prot: H2BFM_HUMAN, P0C1H6Similarity: Belongs to the histone H2B family | Gene Function
for H2BFM
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| Browse Origene for 29mer shRNA kit in GFP-retroviral vector
 Applied Biosystems Silencer® siRNAs for H2BFM
 Sigma-Aldrich siRNA for H2BFM
Sigma-Aldrich shRNA for H2BFM
Explore Sigma-Aldrich super-pooled esiRNAs
Browse Origene for untagged/tagged cDNA clones in CMV expression vector
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
Browse Origene genome-wide validated SYBR primer pairs
UniProtKB/Swiss-Prot: H2BFM_HUMAN, P0C1H6Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting
DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby
play a central role in transcription regulation, DNA repair, DNA replication and chromosomal
stability. DNA accessibility is regulated via a complex set of post-translational modifications of
histones, also called histone code, and nucleosome remodeling1 Gene Ontology (GO) molecular function term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- |
About this table | Pathways & Interactions
for H2BFM
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006334 | nucleosome assembly |
IEA | -- |
About this table
|
Drugs & Compounds
for H2BFM(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for H2BFM
|
Transcripts
for H2BFM(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene)
About This Section
| Browse Origene for 29mer shRNA kit in GFP-retroviral vector
Sigma-Aldrich siRNA for H2BFM
Sigma-Aldrich shRNA for H2BFM
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: XM_001723437
Browse Origene for untagged/tagged cDNA clones in CMV expression vector
Additional cDNA sequence: AK093522.1 XM_001723437.1 1 DOTS entry: DT.99998582 4 AceView cDNA sequences:AI018051 AK093522 AX748182 AI827900
 highest scoring ESTs for H2BFM:AK093522 AI018051 AI827900 AX748182 DB041370 DB337867 XM_210048 Unigene Cluster for H2BFM: H2B histone family, member M Hs.376474 [show with all ESTs]Unigene Representative Sequence: XM_001723437
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations: ENST00000355016
ENST00000243297
|
Expression
for H2BFM
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| H2BFM expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for H2BFM
1 / 2 5 probe-sets matching H2BFM gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: AAACAAAAGC
SOURCE GeneReport for Unigene cluster: Hs.376474
|
Orthologs
for H2BFM
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for H2BFM | Paralogs
for H2BFM(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for H2BFM gene
- H2BFWT2
|
SNPs/Variants
for H2BFM(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for H2BFM (up to first 250kb)
|
Disorders & Mutations
for H2BFM
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News
for H2BFM(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for H2BFM (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 2 PubMed articles for H2BFM gene: |
Search for H2BFM
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing H2BFM
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing H2BFM
(According to HUGE)
About This Section
| -- |
Specialized Databases showing H2BFM(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for H2BFM(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for H2BFM:
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| | |  | Search Tocris compounds for H2BFM |
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