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H2AFY2 Gene

protein-coding   GIFtS: 57
GCID: GC10P071812

H2A Histone Family, Member Y2

  Search for H2AFY2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
H2A Histone Family, Member Y21 2     Core Histone MacroH2A2.22
Histone MacroH2A22 3     macroH2A22
mH2A22 3     MACROH2A23
Core Histone Macro-H2A.22     

External Ids:    HGNC: 144531   Entrez Gene: 555062   Ensembl: ENSG000000992847   UniProtKB: Q9P0M63   

Export aliases for H2AFY2 gene to outside databases

Previous GC identifers: GC10P070623 GC10P070899 GC10P071704 GC10P071157 GC10P071482 GC10P065804


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for H2AFY2 Gene:
H2AFY2 (H2A histone family, member Y2) is a protein-coding gene. GO annotations related to this gene include protein heterodimerization activity. An important paralog of this gene is H2AFB1.

UniProtKB/Swiss-Prot: H2AW_HUMAN, Q9P0M6
Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses
transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular
machineries which require DNA as a template. Histones thereby play a central role in transcription regulation,
DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of
post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be
involved in stable X chromosome inactivation

Gene Wiki entry for H2AFY2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the H2AFY2 gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   Spz1   oct-B3   oct-B2   POU2F2   POU2F1   POU2F1a   c-Myb   POU2F2B   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidH2AFY2 promoter sequence
   Search Chromatin IP Primers for H2AFY2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat H2AFY2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.1   Ensembl cytogenetic band:  10q22.1   HGNC cytogenetic band: 10q22.1

H2AFY2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
H2AFY2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P071812:  view genomic region     (about GC identifiers)

Start:
71,812,357 bp from pter      End:
71,872,040 bp from pter
Size:
59,684 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: H2AW_HUMAN, Q9P0M6 (See protein sequence)
Recommended Name: Core histone macro-H2A.2  
Size: 372 amino acids; 40058 Da
Subunit: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one
H3-H4 heterotetramer and two H2A-H2B heterodimers
1 PDB 3D structure from and Proteopedia for H2AFY2:
2XD7 (3D)    
Secondary accessions: Q5SQT2

Explore the universe of human proteins at neXtProt for H2AFY2: NX_Q9P0M6

Explore proteomics data for H2AFY2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys116, Lys332
  • Modification sites at PhosphoSitePlus

  • See H2AFY2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_061119.1  
    ENSEMBL proteins: 
     ENSP00000362352   ENSP00000404584  

    H2AFY2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RIH: Histones / Replication-independent

    5 InterPro protein domains:
     IPR009072 Histone-fold
     IPR002589 Macro_dom
     IPR007125 Histone_core_D
     IPR002119 Histone_H2A
     IPR021171 Core_histone_macro-H2A

    Graphical View of Domain Structure for InterPro Entry Q9P0M6

    ProtoNet protein and cluster: Q9P0M6

    2 Blocks protein domains:
    IPB002119 Histone H2A
    IPB002589 Protein of unknown function Appr-1


    UniProtKB/Swiss-Prot: H2AW_HUMAN, Q9P0M6
    Similarity: Contains 1 histone H2A domain
    Similarity: Contains 1 Macro domain


    Find genes that share domains with H2AFY2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: H2AW_HUMAN, Q9P0M6
    Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses
    transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular
    machineries which require DNA as a template. Histones thereby play a central role in transcription regulation,
    DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of
    post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be
    involved in stable X chromosome inactivation

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0046982protein heterodimerization activity IEA--
         
    Find genes that share ontologies with H2AFY2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for H2AFY2:
     Increased cell number in G2M,  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for H2AFY2
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    miRNA
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    miRTarBase miRNAs that target H2AFY2:
    hsa-mir-769-5p (MIRT039151)

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    Addgene plasmids for H2AFY2 

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    H2AW_HUMAN, Q9P0M6: Nucleus. Chromosome. Note=Enriched in inactive X chromosome chromatin and in
    senescence-associated heterochromatin
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    mitochondrion3
    cytosol2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000786nucleosome IEA--
    GO:0001740Barr body IDA11331621
    GO:0005634nucleus IDA--

    Find genes that share ontologies with H2AFY2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for H2AFY2 About    
    See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase I Promoter Opening
    Systemic lupus erythematosus0.40
    Alcoholism0.34


    Find genes that share SuperPaths with H2AFY2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    2 Kegg Pathways  (Kegg details for H2AFY2):
        Alcoholism
    Systemic lupus erythematosus

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for H2AFY2
    Interactions:

        Search GeneGlobe Interaction Network for H2AFY2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for H2AFY2 (Q9P0M63 ENSP000003623524) via UniProtKB, MINT, STRING, and/or I2D (see all 49)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    WDR6Q9NNW53I2D: score=1 
    EZH2ENSP000003201474STRING: ENSP00000320147
    HDAC2ENSP000003813314STRING: ENSP00000381331
    SUZ12ENSP000003165784STRING: ENSP00000316578
    HDGFENSP000003571894STRING: ENSP00000357189
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly IEA--
    GO:0007549dosage compensation IDA11331621
    GO:0016568chromatin modification IEA--

    Find genes that share ontologies with H2AFY2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for H2AFY2 (H2AW)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for H2AFY2 gene: 
    NM_018649.2  

    Unigene Cluster for H2AFY2:

    H2A histone family, member Y2
    Hs.499953  [show with all ESTs]
    Unigene Representative Sequence: AL359572
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373255(uc001jqm.3) ENST00000455786
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidH2AFY2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat H2AFY2
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat H2AFY2
      QuantiTect SYBR Green Assays in human, mouse, rat H2AFY2
      QuantiFast Probe-based Assays in human, mouse, rat H2AFY2

    Additional mRNA sequence: 

    AF336304.1 AK022475.1 AK022776.1 AK131057.1 AL359572.1 BC016172.2 

    9 DOTS entries:

    DT.416777  DT.91766758  DT.100714171  DT.102829851  DT.91766762  DT.95312865  DT.100792928  DT.106028 
    DT.416778 

    Selected AceView cDNA sequences (see all 207):

    F11341 AI910812 BU623795 BC016172 BI820969 CR613322 CN481762 BE696056 
    CR601217 AA318946 BE464932 D53709 BU683296 AI569683 BX353537 BM680187 
    CR613570 BG055758 AI767655 AA678734 BU902562 BE551612 BE047110 AA283182 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    H2AFY2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTTTTCCTC
    H2AFY2 Expression
    About this image


    H2AFY2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 14) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 2 entries
             PureStem 4D20.8, NCr-fac Progenitor
     
     Lateral Plate Mesoderm (Gastrulation Derivatives)    fully expand to see all 2 entries
             PureStem E15, Meso-prx/latp Progenitor
     
     Primitive Streak (Early Embryonic Tissues)
             Primitive streak-like cells
    H2AFY2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    H2AFY2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.499953
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for H2AFY2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia H2afy21 , 5 H2A histone family, member Y21, 5 90.23(n)1
    98.39(a)1
      10 (32.27 cM)5
    4046341  NM_207000.21  NP_996883.11 
     617386655 
    chicken
    (Gallus gallus)
    Aves H2AFY21 H2A histone family, member Y2 80.11(n)
    90.32(a)
      423721  NM_001277338.2  NP_001264267.1 
    lizard
    (Anolis carolinensis)
    Reptilia H2AFY26
    H2A histone family, member Y2
    87(a)
    1 ↔ 1
    3(48801361-48832837)
    African clawed frog
    (Xenopus laevis)
    Amphibia h2afy2-prov2 H2A histone family, member Y2 76.1(n)    BC056065.1 
    zebrafish
    (Danio rerio)
    Actinopterygii h2afy21 H2A histone family, member Y2 69.49(n)
    73.77(a)
      558711  NM_001025502.1  NP_001020673.1 
    worm
    (Caenorhabditis elegans)
    Secernentea htas-16
    Protein HTAS-1 (htas-1) mRNA, complete cds
    39(a)
    1 → many
    IV(9682984-9683532) WBGene00014240


    ENSEMBL Gene Tree for H2AFY2 (if available)
    TreeFam Gene Tree for H2AFY2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for H2AFY2 gene
    H2AFB12  H2AFB22  H2AFB32  H2AFY2  
    Selected SIMAP similar genes for H2AFY2 using alignment to 2 protein entries:     H2AW_HUMAN (see all proteins) (see all similar genes):
    HIST1H2AA    HIST1H2AB    HIST1H2AE    HIST2H2AB    HIST3H2A    HIST1H2AC
    HIST1H2AD    HIST2H2AC    H2AFV    H2AFJ    H2AFX    H2AFZ
    HIST1H2AG    HIST1H2AH    HIST1H2AI    HIST1H2AJ    HIST1H2AK    HIST1H2AL

    Find genes that share paralogs with H2AFY2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for H2AFY2 (see all 1181)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1451958931,2
    --71810380(+) ATGTTC/TGGTAT 1 -- us2k10--------
    rs339192251,2
    C,F--71810578(+) CTATAA/GCAAAG 1 -- us2k112Minor allele frequency- G:0.46NA WA CSA EA 374
    rs1840019191,2
    --71810700(+) CCAACA/CAGTAT 1 -- us2k10--------
    rs1885384021,2
    --71810727(+) AACCAG/TTAAAT 1 -- us2k10--------
    rs1147509791,2
    C,F--71810951(+) GAAAAC/TTCCTG 1 -- us2k11Minor allele frequency- T:0.05WA 118
    rs1423403121,2
    --71811073(+) CCCCAA/GGGGAT 1 -- us2k10--------
    rs1469150471,2
    --71811117(+) AAGAAG/TACTTT 1 -- us2k10--------
    rs1918344671,2
    --71811176(+) AGTGAA/GGTCAT 1 -- us2k10--------
    rs1393310341,2
    --71811660(+) CCTCTC/TACAGT 1 -- us2k10--------
    rs765045631,2
    F--71811671(+) CCTTTG/AACTGT 1 -- us2k11Minor allele frequency- A:0.01WA 118

    HapMap Linkage Disequilibrium report for H2AFY2 (71812357 - 71872040 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for H2AFY2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv819142CNV Gain19587683
    esv32737CNV Gain+Loss17666407

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with H2AFY2           About GenesLikeMe

    Genetic Association Database (GAD): H2AFY2
    Human Genome Epidemiology (HuGE) Navigator: H2AFY2 (2 documents)

    Export disorders for H2AFY2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for H2AFY2 gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with H2AFY2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant. (PubMed id 11331621)1, 2, 3, 9 Chadwick B.P. and Willard H.F. (Hum. Mol. Genet. 2001)
    2. MACROH2A2, a new member of the MACROH2A core histone family. (PubMed id 11262398)1, 2, 3 Costanzi C. and Pehrson J.R. (J. Biol. Chem. 2001)
    3. Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. (PubMed id 20080650)1, 4 Xu J....Isaacs W.B. (Proc. Natl. Acad. Sci. U.S.A. 2010)
    4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    5. Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. (PubMed id 15621527)1, 2 Zhang R.... Adams P.D. (Dev. Cell 2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55506 HGNC: 14453 AceView: H2AFY2 Ensembl:ENSG00000099284 euGenes: HUgn55506
    ECgene: H2AFY2 Kegg: 55506 H-InvDB: H2AFY2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for H2AFY2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for H2AFY2 gene:
    Search GeneIP for patents involving H2AFY2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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