Aliases for H2AFY2 Gene
External Ids for H2AFY2 Gene
Previous GeneCards Identifiers for H2AFY2 Gene
GeneCards Summary for H2AFY2 Gene
H2AFY2 (H2A Histone Family, Member Y2) is a Protein Coding gene. Among its related pathways are RNA Polymerase I Promoter Opening and RNA Polymerase I Promoter Opening. GO annotations related to this gene include protein heterodimerization activity. An important paralog of this gene is H2AFB2.
UniProtKB/Swiss-Prot for H2AFY2 Gene
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.