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H2AFV Gene

protein-coding   GIFtS: 53

GC07M044833
H2A histone family, member V
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: H2AV)
Services    

Aliases &
Descriptions
for H2AFV

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
FLJ26479 2
H2A.F/Z 3
H2AV 2, 3
MGC10170 1, 2
MGC10831 1, 2
MGC1947 1, 2
Descriptions
H2A histone family, member V 2
histone H2A.F/Z 2
purine-rich binding element protein B 2
External Ids
HGNC: 206641
Entrez Gene: 942392
UniProtKB: Q71UI93
Ensembl: ENSG000001059687
Search outside databases for aliases for H2AFV gene

Previous GC identifers: GC07M044610 GC07M044642

Summaries
for H2AFV

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for H2AFV:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the
chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around
a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The
chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA
between the nucleosomes to form higher order chromatin structures. This gene encodes a member of
the histone H2A family. Several transcript variants encoding different isoforms, have been
identified for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: H2AV_HUMAN, Q71UI9
Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular
machineries which require DNA as a template. Histones thereby play a central role in transcription
regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated
via a complex set of post-translational modifications of histones, also called histone code, and
nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be
required for chromosome segregation during cell division (By similarity)

Gene Wiki entry for H2AFV

Genomic Location
for H2AFV

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the H2AFV gene  

Entrez Gene cytogenetic band: 7p13   Ensembl cytogenetic band:  7p13   HGNC cytogenetic band: 7p13

H2AFV Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M044833:     (about GC identifiers)

Start:
 44,833,013 bp from pter
End:
 44,854,255 bp from pter
Size:
 21,243 bases
Orientation:
 minus strand

1 alternative location:
Chr7-,CRA_TCAG 44,905,993-44,927,227     
RefSeq DNA sequence:
NC_000007.12  NT_007819.16  NT_079592.2  

Proteins
for H2AFV

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: H2AV_HUMAN, Q71UI9 (See protein sequence)
Recommended Name: Histone H2A.V  
Size: 128 amino acids; 13509 Da
Subunit: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4
assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps
approximately 147 bp of DNA. H2A or its variant H2AFV forms an heterodimer with H2B (By
similarity)
Subcellular location: Nucleus (By similarity)
Mass spectrometry: Mass=13369.4; Method=Electrospray; Range=2-128; Note=Monoisotopic, not modified;
Source=PubMed:16457589;
Secondary accessions: Q59GV8 Q6PK98

Post-translational modifications:

  • Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression (By
    similarity)1
  • Acetylated on Lys-5, Lys-8 and Lys-12 during interphase. Acetylation disappears at mitosis (By
    similarity)1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (5 alternative transcripts): 
    NP_036544.1  NP_619541.1  NP_958844.1  NP_958924.1  NP_958925.1  


    ENSEMBL proteins: 
    ENSP00000370516 ENSP00000308405 ENSP00000342714 ENSP00000340708 ENSP00000222690 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse Abcam for Recombinant Proteins
    Human Recombinant Proteins from Abnova (H2AFV)
                   OriGene Purified Recombinant Human Proteins (see all 2): H2AFV  

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000786 nucleosome IEA--
    GO:0005634 nucleus IEA--
    GO:0005694 chromosome IEA--
    About this table

    Antibodies for H2AFV: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse Antibodies at Sigma-Aldrich
    Browse R&D Systems for Antibodies
    Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
    Monoclonal and Polyclonal Antibodies from Abnova (H2AFV)
    Novus Biologicals Antibody for H2AFV

    Assays for H2AFV: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for H2AFV

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro domains/families:
     IPR007125 Histone_core_D
     IPR002119 Histone_H2A
     IPR009072 Histone-fold


       GeneDecks  H2AFV for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q71UI9

    ProtoNet protein and cluster: Q71UI9

    1 Blocks protein family: IPB002119 Histone H2A

    UniProtKB/Swiss-Prot: H2AV_HUMAN, Q71UI9
    Similarity: Belongs to the histone H2A family

    Gene Function
    for H2AFV

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (H2AFV)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (H2AFV)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 5): NM_201436

                  Applied Biosystems Silencer® siRNAs for H2AFV

                  Sigma-Aldrich siRNA for H2AFV  
                         Sigma-Aldrich shRNA for H2AFV  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Browse Clone Ranger at Invitrogen for clones
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 5): NM_012412
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 5): NM_012412
                                     untagged cDNA clones in CMV expression vector (see all 5): NM_012412 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_012412

    UniProtKB/Swiss-Prot: H2AV_HUMAN, Q71UI9
    Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
    Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular
    machineries which require DNA as a template. Histones thereby play a central role in transcription
    regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated
    via a complex set of post-translational modifications of histones, also called histone code, and
    nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be
    required for chromosome segregation during cell division (By similarity)

    1 Gene Ontology (GO) molecular function term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677 DNA binding IEA--
    About this table

    Pathways & Interactions
    for H2AFV

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Kegg Pathway  (Kegg details for H2AFV):
     hsa05322 Systemic lupus erythematosus

       GeneDecks  H2AFV for the pathways selected above  
    About GeneDecksing

    5/10 Interacting proteins for H2AFV (ENSP000003705163) via UniProtKB, MINT, and/or STRING (see all 10 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KAT5ENSP000003403303STRING (score=.897)
    EP400ENSP000003336023STRING (score=.864)
    HIST2H2BEENSP000003364173STRING (score=.825)
    CBX5ENSP000002098753STRING (score=.732)
    HVCN1ENSP000003491813STRING (score=.728)
    About this table

    1 Gene Ontology (GO) biological process term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334 nucleosome assembly IEA--
    About this table

    Drugs & Compounds
    for H2AFV

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for H2AFV

    Transcripts
    for H2AFV

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (H2AFV)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (H2AFV)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 5): NM_201436

                  Sigma-Aldrich siRNA for H2AFV  
                         Sigma-Aldrich shRNA for H2AFV  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_012412  NM_138635  NM_201436  NM_201516  NM_201517  

    REFSEQ mRNAs for H2AFV gene (5 alternative transcripts): 

    NM_012412.4   NM_138635.3   NM_201436.2   NM_201516.2   NM_201517.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_012412  NM_138635  NM_201436  NM_201516  NM_201517  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 5): NM_012412
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 5): NM_012412
                                     untagged cDNA clones in CMV expression vector (see all 5): NM_012412 

    Additional cDNA sequence: 

    AB209001.1 AF081192.1 AK023973.1 AK025785.1 AK129989.1 AL049324.1 AL110212.1 BC000098.2 
    BC004274.1 BC014885.2 BC070169.1 CR602318.1 CR615278.1 

    21 DOTS entries:

    DT.315938  DT.92419758  DT.40276722  DT.121041856  DT.91678836  DT.100752399  DT.102834611  DT.455590 
    DT.121056042  DT.95147928  DT.40249279  DT.100787929  DT.97824733  DT.121041904  DT.121041877  DT.121041911 
    DT.95205511  DT.100752397  DT.121041857  DT.121056043  DT.91852611 

    24/642 AceView cDNA sequences (see all 642 ):

    BG110804 AI611731 BC004274 BU856693 BM715562 CN482679 BM477489 BG478206 
    AW020017 BM916370 AA279180 CR615278 AW135134 AI760346 BE794116 AW057661 
    BE551673 BM556787 BG574251 AU121195 BG168182 AI760880 BE794243 AI140183 

    highest scoring ESTs for H2AFV:

    AA203494 AA305274 AF081192 AI634570 AK023973 AK129989 AL520811 AU142364 AW007731 AW839014 

    Unigene Cluster for H2AFV:

    H2A histone family, member V
    Hs.488189  [show with all ESTs]
    Unigene Representative Sequence: AL110212


    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for H2AFV (see all 7 )

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b
    SP1:                                -                                 
    SP2:                                -     -     -     -               
    SP3:                    -           -     -     -     -               
    SP4:                          -     -                                 
    SP5:              -                 -                                 

    About this scheme

    ECgene alternative splicing isoforms for H2AFV

    5 Ensembl transcripts including schematic representations:
    ENST00000381124  ENST00000308153  ENST00000349299  ENST00000350771  ENST00000222690  

    Expression
    for H2AFV

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    H2AFV expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for H2AFV

    1 / 2 / 3

    12 probe-sets matching H2AFV gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    39092_at2, 3 U95-A 2 1.00 0.97 0.88 0.94 AW007731 0.80 1.00 0.91 1

    		44821_at2, 3 U95-B 2 1.00 0.94 0.93 1.08 AI634570 0.80 1.00 0.91 1
    77491_at2, 3 U95-E 2 0.69 0.91 0.47 0.90 H97000 0.80 1.00 0.91 1

    		39046_at2, 3 U95-A 1 0.38 1.00 0.02 1.09 AL049324 0.60 1.00 0.82 1

    		212206_s_at2, 3 U133-A 1 1.00 1.00 -- -- BF343852 0.60 1.00 0.82 1

    		227085_at2, 3 U133-B 1 1.00 1.00 -- -- AI823792 0.60 1.00 0.82 1

    		202487_s_at2, 3 U133-A 3 1.00 0.56 -- -- NM_012412 0.60 1.00 0.82 1

    		212205_at2, 3 U133-A 1 0.64 1.00 -- -- AA534860 0.60 1.00 0.82 1

    		212206_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		227085_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		202487_s_at2 U133Plus2 3 1.00 0.56 -- -- -- -- -- -- --

    		212205_at2 U133Plus2 1 0.64 1.00 -- -- -- -- -- -- --
    GeneDecks  H2AFV for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene cluster: Hs.488189

    Expression variation in blood from EXPOLDB for H2AFV

    Orthologs
    for H2AFV

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for H2AFV gene from 5/19 species (see all 19 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 LOC4755011   -- similar to H2A histone family, member V isoform 5 94.01(n)
    100(a)    		 475501  XM_532724.2  XP_532724.1 
    chimpanzee
    (Pan troglodytes)    		 LOC4642251   -- hypothetical LOC464225 78.22(n)
    91.34(a)    		 464225  XM_001163743.1  XP_001163743.1 
    cow
    (Bos taurus)    		 H2AFV1   -- H2A histone family, member V 94.27(n)
    100(a)    		 613618  NM_001038197.1  NP_001033286.1 
    rat
    (Rattus norvegicus)    		 RGD15608131   -- similar to H2A histone family, member V isoform 1 92.45(n)
    99.22(a)    		 498894  XM_574181.2  XP_574181.2 
    mouse
    (Mus musculus)    		 H2afv5 11 H2A histone family, member V   -- BC147751 
    About this table        Species with no ortholog for H2AFV

    ENSEMBL Gene Tree for H2AFV

    Paralogs
    for H2AFV

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for H2AFV gene
    H2AFY22  H2AFZ2  H2AFY2  

    SNPs/Variants
    for H2AFV

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/125 NCBI SNPs in H2AFV are shown (see all 125 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 29)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 7 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs7576931,2
    		A,C,F,H,O44854554(+) TGCAGG/ACGCTG 5 -- ng317Minor allele frequency- A:0.31MN EU EA WA NA 784
    rs28981,2
    		A,C,F,H,O44833158(+) TTGTCA/GTTTGG 1 -- ut3113Minor allele frequency- G:0.31MN NA EU EA WA 1116
    rs12978371,2
    		A,C,F,O44836062(+) AAAAGT/CGCTCT 1 -- ut31 ese34Minor allele frequency- C:0.33MN NA 326
    rs28971,2
    		A,C,F,H44833229(+) GAAAAA/GAAGTG 1 -- ut3110Minor allele frequency- G:0.47MN NA EU EA WA 942
    rs117706841,2
    		A,C,F,H44834627(+) TCATCG/ACCACT 1 -- ut314Minor allele frequency- A:0.49EU EA WA 420
    --
    rs11357601,2
    		A,C,F,H44834972(-) gaagaG/Aagcac 1 -- ut319Minor allele frequency- A:0.42MN EU EA WA 1022
    rs20179341,2
    		C,F,H44835801(+) GGAATG/AGGATG 1 -- ut31 ese38Minor allele frequency- A:0.02MN EU EA WA NA 742
    rs102609641,2
    		A,C,F44839969(+) GGCAGC/GAACAA 5 -- ut31 int13Minor allele frequency- G:0.45NA 124
    rs69703331,2
    		C,F,H44833530(+) TCCTCA/GTGAAG 1 -- ut31 ese34Minor allele frequency- G:0.01EU EA WA 418
    rs70161,2
    		C,F,H44833357(-) AAATAA/CAACTG 1 -- ut3113Minor allele frequency- C:0.25MN NA EU EA WA 1348
    About this table

    HapMap Linkage Disequilibrium images for H2AFV (up to first 250kb)

    Disorders & Mutations
    for H2AFV

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		   --

    Medical News
    for H2AFV

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for H2AFV

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/13 PubMed articles for H2AFV gene (see all 13 ):

    Search for H2AFV

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing H2AFV

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 94239 HGNC: 20664 AceView: H2AFV Ensembl:ENSG00000105968 euGenes: HUgn94239
    ECgene: H2AFV H-InvDB: H2AFV

    Other Databases showing H2AFV

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing H2AFV

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    		   --

    Licensable Technologies
    for H2AFV

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for H2AFV

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for H2AFV:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
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      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for H2AFV-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for H2AFV Browse antibodies at Sigma-Aldrich
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for H2AFV Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
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     Recombinant & Natural Proteins  

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