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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

H1FOO Gene

protein-coding   GIFtS: 47
GCID: GC03P129262

H1 histone family, member O, oocyte-specific
 Explore 1 disease affiliated with
H1FOO via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for H1FOO    

Aliases
for H1FOO gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
H1 Histone Family, Member O, Oocyte-Specific1 2     Histone H1oo2
Oocyte-Specific Histone H12 3     H1OO3
Oocyte-Specific Linker Histone H12 3     OSH13
OsH11     

External Ids:    HGNC: 184631   Entrez Gene: 1322432   Ensembl: ENSG000001788047   UniProtKB: Q8IZA33   

Export aliases for H1FOO gene to outside databases

Previous GC identifers: GC03P130543 GC03P130582 GC03P130744 GC03P126645


Summaries
for H1FOO gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for H1FOO:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in
eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of
each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the
interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.
The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The
protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes. (provided
by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: H1FOO_HUMAN, Q8IZA3
Function: May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably
through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes.
The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The
greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the
embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling
(By similarity)

Gene Wiki entry for H1FOO


Genomic Views
for H1FOO gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the H1FOO gene promoter:
         c-Fos   PPAR-gamma1   AP-1   HFH-1   c-Jun   NF-kappaB1   NF-kappaB   YY1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: H1FOO promoter sequence
   Search SABiosciences Chromatin IP Primers for H1FOO

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat H1FOO


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q22.1   Ensembl cytogenetic band:  3q22.1   HGNC cytogenetic band: 3q21.3

H1FOO Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
H1FOO gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P129262:  view genomic region     (about GC identifiers)

Start:
 129,262,057 bp from pter      End:
 129,270,310 bp from pter
Size:
 8,254 bases      Orientation:
 plus strand

Proteins
for H1FOO gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: H1FOO_HUMAN, Q8IZA3 (See protein sequence)
Recommended Name: Histone H1oo  
Size: 346 amino acids; 35813 Da
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity). Chromosome (By similarity)
Secondary accessions: Q86WT7
Alternative splicing: 2 isoforms:  Q8IZA3-1   Q8IZA3-2   

Explore the universe of human proteins at neXtProt for H1FOO: NX_Q8IZA3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8IZA3

    • H1FOO Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_722575.1  
    ENSEMBL proteins: 
     ENSP00000319799   ENSP00000422964  

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    Novus Biologicals H1FOO Protein
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    Uscn Proteins for H1FOO

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000786nucleosome IEA--
    GO:0001674female germ cell nucleus IEA--
    GO:0005737cytoplasm IEA--


    H1FOO for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for H1FOO gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    H1FOO for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR011991 WHTH_trsnscrt_rep_DNA-bd_dom
     IPR005818 Histone_H1/H5

    Graphical View of Domain Structure for InterPro Entry Q8IZA3

    ProtoNet protein and cluster: Q8IZA3

    1 Blocks protein family: IPB005818 Histone H1/H5

    UniProtKB/Swiss-Prot: H1FOO_HUMAN, Q8IZA3
    Similarity: Belongs to the histone H1/H5 family
    Similarity: Contains 1 H15 (linker histone H1/H5 globular) domain


    Function
    for H1FOO gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: H1FOO_HUMAN, Q8IZA3
    Function: May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably
    through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes.
    The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The
    greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the
    embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling
    (By similarity)

    miRNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--


    H1FOO for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for H1FOO:
     Decreased Wnt reporter activit 

    Animal Models:
         Mouse knock-out H1footm1Eya for H1FOO
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for H1foo):
     normal 

    H1FOO for phenotypes           About GeneDecksing


    Pathways & Interactions
    for H1FOO gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell cycle_Start of DNA replication in early S phase
    		Cell cycle_Start of DNA replication in early S phase1.00
    		Cell cycle Start of DNA replication in early S phase0.98
    2Cell cycle Chromosome condensation in prometaphase
    		Cell cycle Chromosome condensation in prometaphase1.00
    		Cell cycle_Chromosome condensation in prometaphase1.00
    3Signal transduction Activin A signaling regulation
    		Histone modification0.31

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    3 EMD Millipore Pathways for H1FOO
        Histone modification
    Cell cycle Start of DNA replication in early S phase
    Cell cycle Chromosome condensation in prometaphase


    2 GeneGo (Thomson Reuters) Pathways for H1FOO
        Cell cycle Chromosome condensation in prometaphase
    Cell cycle Start of DNA replication in early S phase



    H1FOO for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for H1FOO

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly IEA--
    GO:0007126meiosis IEA--


    H1FOO for ontologies           About GeneDecksing



    Drugs & Compounds
    for H1FOO gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for H1FOO
    Search CenterWatch for drugs/clinical trials and news about H1FOO 

    Transcripts
    for H1FOO gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for H1FOO gene: 
    NM_153833.1  

    Unigene Cluster for H1FOO:

    H1 histone family, member O, oocyte-specific
    Hs.97358  [show with all ESTs]
    Unigene Representative Sequence: BM564157
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000324382(uc003emu.3) ENST00000503977(uc003emv.3)

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: H1FOO
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat H1FOO
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat H1FOO

    Additional cDNA sequence: 

    AY158091.1 BC047943.1 

    2 DOTS entries:

    DT.99997933  DT.40118992 

    6 AceView cDNA sequences:

    AY158091 NM_153833 BC047943 AA393036 BM564157 AA412165 

    GeneLoc Exon Structure


    Expression
    for H1FOO gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    H1FOO expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    H1FOO expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Secondary follicles (Primary Cell)Ovary, Reproductive System
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See H1FOO Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for H1FOO

    SOURCE GeneReport for Unigene cluster: Hs.97358

    UniProtKB/Swiss-Prot: H1FOO_HUMAN, Q8IZA3
    Tissue specificity: Oocyte-specific

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    In Situ
    Assay Products:     
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    Orthologs
    for H1FOO gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for H1FOO gene from 6/21 species (see all 21)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia H1foo1 , 5 H1 histone family, member O, oocyte-specific1, 5 65.53(n)1
    52.05(a)1    		   6 (53.72 cM)5
    1715061  NM_138311.21  NP_612184.11 
     1159449385 
    chicken
    (Gallus gallus)    		 Aves H1FOO1 H1 histone family, member O, oocyte-specific 52.42(n)
    43.55(a)    		   771929  XM_001235136.2  XP_001235137.2 
    zebrafish
    (Danio rerio)    		 Actinopterygii h1m1 linker histone H1M 42.72(n)
    36.11(a)    		   327403  NM_183071.2  NP_898894.2 
    worm
    (Caenorhabditis elegans)    		 Secernentea his-246
    hil-66
    (see all 7)    		 Putative histone H1.6
    (see all 7)    		 21(a)
    20(a)
    (see all 7)    		 many → 1
    many → 1
    (see all 7)    		 X(14490037-14491045)
    V(2030656-2031474)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons HIS1-36
    AT2G306206
    (see all 3)    		 histone H1.2
    (see all 3)    		 17(a)
    17(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 2(7845923-7846884)
    2(13044931-13046663)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 4)    		 histone H1, putative, expressed
    (see all 4)    		 23(a)
    15(a)
    (see all 4)    		 many ↔ many
    many ↔ many
    (see all 4)    		 4(9984198-9985211)
    6(1641215-1642801)


    ENSEMBL Gene Tree for H1FOO (if available)
    TreeFam Gene Tree for H1FOO (if available) 

    Paralogs
    for H1FOO gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for H1FOO gene
    HIST1H1T2  HIST1H1D2  H1F02  HIST1H1E2  HIST1H1C2  HIST1H1B2  H1FX2  HIST1H1A2  

    H1FOO for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for H1FOO
    PGOHUM00000247863 PGOHUM00000237646


    Genomic Variants
    for H1FOO gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/223 NCBI SNPs in H1FOO are shown (see all 223)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs629669621,2
    		C,--129260068(+) ACACA-/CACACAC 1 -- us2k10--------
    rs341218041,2
    		C--129260069(+) ACACA-/ACCACAC 1 -- us2k11Minor allele frequency- AC:0.50NA 2
    rs67706911,2
    		C,--129260169(+) tactgC/Tatact 1 -- us2k14Minor allele frequency- T:0.12WA NA EA 360
    rs19054431,2
    		C,F,A,H,--129260170(+) ACTGCG/ATACTA 1 -- us2k116Minor allele frequency- A:0.40NS EA WA NA CSA 858
    rs1483575281,2
    		--129260186(+) CTGTGC/TGAATA 1 -- us2k10--------
    rs1163281671,2
    		F,--129260214(+) TCACTC/TTCCAC 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs788521871,2
    		C,F,--129260385(+) TAAGGC/TGGCTA 1 -- us2k11Minor allele frequency- T:0.03EA 120
    rs1919890511,2
    		--129260451(+) CTATTA/GATAGA 1 -- us2k10--------
    rs1838052531,2
    		--129260459(+) AGACAC/GTTACA 1 -- us2k10--------
    rs2018421821,2
    		--129260532(+) CCCCC-/TTTTTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for H1FOO (129262057 - 129270310 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for H1FOO: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing H1FOO
    DNA2.0 Custom Variant and Variant Library Synthesis for H1FOO

    Disorders / Diseases
    for H1FOO gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    H1FOO for disorders           About GeneDecksing

    1 disease for H1FOO:    About MalaCards
    premature ovarian failure

    1 disease from the University of Copenhagen DISEASES database for H1FOO:
    Premature ovarian failure

    Export disorders for H1FOO gene to outside databases

    Publications
    for H1FOO gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for H1FOO gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with H1FOO)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Structure and expression of the human oocyte-specific histone H1 gene elucidated by direct RT-nested PCR of a single oocyte. (PubMed id 12711322)1, 2, 9 Tanaka Y.... Yoshimura Y. (2003)
    2. The human and mouse replication-dependent histone genes. (PubMed id 12408966)1, 3 Marzluff W.F....Maltais L.J. (2002)
    3. Expression of human oocyte-specific linker histone pr otein and its incorporation into sperm chromatin during fertilization. (PubMed id 19147139)1 Mizusawa Y....Yoshimura Y. (2010)
    4. H1FOO is coupled to the initiation of oocytic growth. (PubMed id 15371275)1 Tanaka M....Adashi E.Y. (2005)
    5. Rapid replacement of somatic linker histones with the oocyte-specific linker histone H1foo in nuclear transfer. (PubMed id 14729479)1 Teranishi T....Yoshimura Y. (2004)
    6. Rapid H1 linker histone transitions following fertilization or somatic cell nuclear transfer: evidence for a uniform developmental program in mice. (PubMed id 14729478)1 Gao S....Latham K.E. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. A rice homeobox gene, OSH1, is expressed before organ differentiation in a specific region during early embryogenesis. (PubMed id 8755613)9 Sato Y....Matsuoka M. (1996)
    10. Initiation of shoot apical meristem in rice: characterization of four SHOOTLESS genes. (PubMed id 10409508)9 Satoh N....Nagato Y. (1999)

    External Searches for H1FOO gene

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    Genome Databases showing H1FOO gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 132243 HGNC: 18463 AceView: H1FOO Ensembl:ENSG00000178804 euGenes: HUgn132243
    ECgene: H1FOO H-InvDB: H1FOO

    Other Databases showing H1FOO gene

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    Specialized Databases showing H1FOO gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for H1FOO Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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