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H1F0 Gene

protein-coding   GIFtS: 58
GCID: GC22P038201

H1 Histone Family, Member 0


(Previous symbol: H1FV)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
H1 Histone Family, Member 01 2     H1-01
H1FV1 2 3 5     H1.01
Histone H1'2 3     H102
Histone H1(0)2 3     H1.0, H1(0), H1-02
H1(0)1     Histone H1.02

External Ids:    HGNC: 47141   Entrez Gene: 30052   Ensembl: ENSG000001890607   OMIM: 1427085   UniProtKB: P073053   

Export aliases for H1F0 gene to outside databases

Previous GC identifers: GC22P034815 GC22P036444 GC22P036525 GC22P021168


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for H1F0 Gene:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in
eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs
of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the
interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin
structures. This gene is intronless and encodes a member of the histone H1 family. (provided by RefSeq, Jul 2008)

GeneCards Summary for H1F0 Gene:
H1F0 (H1 histone family, member 0) is a protein-coding gene. An important paralog of this gene is HIST1H1T.

UniProtKB/Swiss-Prot: H10_HUMAN, P07305
Function: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The
H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell
division




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the H1F0 gene promoter:
         Pax-5   Pax-6   Lmo2   GATA-2   CREB   PPAR-gamma1   deltaCREB   STAT3   PPAR-gamma2   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for H1F0

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat H1F0


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q13.1   HGNC cytogenetic band: 22q13.1

H1F0 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
H1F0 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P038201:  view genomic region     (about GC identifiers)

Start:
38,201,114 bp from pter      End:
38,203,443 bp from pter
Size:
2,330 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: H10_HUMAN, P07305 (See protein sequence)
Recommended Name: Histone H1.0  
Size: 194 amino acids; 20863 Da
Rna editing: Modified_positions=Not_applicable; Note=Partially edited. In approximately 3.6% of the mRNA
molecules, a new initiator methionine is created by a single uridine insertion in the 5'-UTR, causing an
N-terminal extension of 99 amino acids. The existence of the RNA edited version is supported by direct protein
sequencing by MS/MS of the following peptides specific to that version: 12-21; 22-33; 37-47; 48-67; 68-83; 84-94
and 97-113. The RNA edited version is called ET-H1.0
Secondary accessions: B2R6I0 B4DRD6 Q6FG88 Q8N6R3
Alternative splicing: 2 isoforms:  P07305-1   P07305-2   

Explore the universe of human proteins at neXtProt for H1F0: NX_P07305

Explore proteomics data for H1F0 at MOPED

Post-translational modifications: 

  • Phosphorylated on Ser-17 in RNA edited version1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See H1F0 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005309.1  
    ENSEMBL proteins: 
     ENSP00000344504  
    Reactome Protein details: P07305

    H1F0 Human Recombinant Protein Products:

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    Sino Biological Recombinant Protein for H1F0
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    Cloud-Clone Corp. Proteins for H1F0

     
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    antibodies-online proteins for H1F0 (20 products) 

     
    antibodies-online peptides for H1F0

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    antibodies-online antibodies for H1F0 (81 products) 

    H1F0 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RIH: Histones / Replication-independent

    3 InterPro protein domains:
     IPR005819 Histone_H5
     IPR011991 WHTH_DNA-bd_dom
     IPR005818 Histone_H1/H5_H15

    Graphical View of Domain Structure for InterPro Entry P07305

    ProtoNet protein and cluster: P07305

    3 Blocks protein domains:
    IPB003216 Linker histone
    IPB005818 Histone H1/H5
    IPB005819 Histone H5 signature


    UniProtKB/Swiss-Prot: H10_HUMAN, P07305
    Similarity: Belongs to the histone H1/H5 family
    Similarity: Contains 1 H15 (linker histone H1/H5 globular) domain


    Find genes that share domains with H1F0           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: H10_HUMAN, P07305
    Function: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The
    H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell
    division
    Induction: Both the unedited and the RNA edited versions are induced by butyrate (at protein level). Only RNA
    edited version is induced by DTT, vinblastine or TNF (at protein level)

         Genatlas biochemistry entry for H1F0:
    linker histone 1 family 0,replacement subtype,replication-independent,involved in basal repression of gene
    expression

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding IPI9499053
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with H1F0           About GenesLikeMe


    Phenotypes:
         4 GenomeRNAi human phenotypes for H1F0:
     Decreased Salmonella enterica   Increased G2M DNA content  Increased cell death HMECs cel  Increased cell death in breast 

         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for H1f0):
     embryogenesis  growth/size/body  hematopoietic system  immune system  mortality/aging 
     normal  reproductive system 

    Find genes that share phenotypes with H1F0           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out H1f0tm1Ais for H1F0

       genOway: Develop your customized and physiologically relevant rodent model for H1F0

    miRNA
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    miRTarBase miRNAs that target H1F0:
    hsa-let-7a-5p (MIRT052457), hsa-mir-423-3p (MIRT042482), hsa-mir-484 (MIRT041752), hsa-mir-181a-5p (MIRT025115), hsa-mir-615-3p (MIRT040432), hsa-mir-186-5p (MIRT045076), hsa-mir-93-5p (MIRT048807)

    Block miRNA regulation of human, mouse, rat H1F0 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate H1F0 (see all 22):
    hsa-miR-345 hsa-miR-3607-3p hsa-miR-520d-5p hsa-let-7a-2* hsa-miR-606 hsa-miR-340 hsa-miR-550a* hsa-miR-4267
    SwitchGear 3'UTR luciferase reporter plasmidH1F0 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat H1F0

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: H1F0 (NM_005318)
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for H1F0


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    H10_HUMAN, P07305: Nucleus. Chromosome. Note=The RNA edited version has been localized to nuclear speckles.
    During mitosis, it appears in the vicinity of condensed chromosomes
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    golgi apparatus4

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000786nucleosome IEA--
    GO:0000790nuclear chromatin IDA19882353
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005794Golgi apparatus IDA--

    Find genes that share ontologies with H1F0           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for H1F0 About   (see all 8)  
    See pathways by source

    SuperPathContained pathways About
    1Activation of DNA fragmentation factor
    Activation of DNA fragmentation factor0.32
    Apoptosis induced DNA fragmentation0.00
    Granzyme-A Pathway0.32
    2Packaging Of Telomere Ends
    DNA Damage/Telomere Stress Induced Senescence0.65
    Formation of Senescence-Associated Heterochromatin Foci (SAHF)0.00
    Histone modification0.31
    3Cellular Senescence
    Cellular Senescence0.81
    Cellular responses to stress0.81
    4Apoptotic cleavage of cellular proteins
    Apoptotic execution phase0.74
    5Activation of cAMP-Dependent PKA
    PKA Signaling0.56


    Find genes that share SuperPaths with H1F0           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for H1F0
        PKA Signaling
    Granzyme-A Pathway

    2 GeneGo (Thomson Reuters) Pathways for H1F0
        Cell cycle Chromosome condensation in prometaphase
    Cell cycle Start of DNA replication in early S phase


    2 Reactome Pathways for H1F0
        Activation of DNA fragmentation factor
    Formation of Senescence-Associated Heterochromatin Foci (SAHF)


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for H1F0
    Interactions:

        Search GeneGlobe Interaction Network for H1F0

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for H1F0 (P073051, 2, 3 ENSP000003445044) via UniProtKB, MINT, STRING, and/or I2D (see all 176)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAD51BO153152, 3MINT-19339 MINT-19342 I2D: score=2 
    NOA1Q8NC602, 3MINT-64923 I2D: score=4 
    YWHAQP273482, 3, ENSP000002380814MINT-7899812 MINT-7900157 I2D: score=1 STRING: ENSP00000238081
    YWHAZP631042, ENSP000003095034MINT-7899812 MINT-7900157 STRING: ENSP00000309503
    HIST1H4FP628052, ENSP000003669744MINT-7899812 MINT-7900157 STRING: ENSP00000366974
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006309apoptotic DNA fragmentation TAS--
    GO:0006334nucleosome assembly IEA--
    GO:0006915apoptotic process TAS--
    GO:0006921cellular component disassembly involved in execution phase of apoptosis TAS--

    Find genes that share ontologies with H1F0           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for H1F0 (H10)

    1 Novoseek inferred chemical compound relationship for H1F0 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    atp 14.2 2 1743293 (1), 16888724 (1)



    Find genes that share compounds with H1F0           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for H1F0 gene: 
    NM_005318.3  

    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000340857(uc003aty.3)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate H1F0 (see all 22):
    hsa-miR-345 hsa-miR-3607-3p hsa-miR-520d-5p hsa-let-7a-2* hsa-miR-606 hsa-miR-340 hsa-miR-550a* hsa-miR-4267
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat H1F0
      QuantiFast Probe-based Assays in human, mouse, rat H1F0

    Selected AceView cDNA sequences (see all 365):

    CR623479 CR617321 AI685457 CR613392 CR609515 CR606842 CR604452 CR542220 
    AA337113 CR456502 CD675060 CK429953 CR623269 AI955178 BM552111 BX460823 
    BX422426 BG035723 BP357059 CR615993 CR620114 AA573531 CR591712 AL539895 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for H1F0    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e · 2f · 2g · 2h
    SP1:                    -     -                           
    SP2:                          -     -                     
    SP3:                    -                                 


    ECgene alternative splicing isoforms for H1F0

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    H1F0 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTGTGTTTG
    H1F0 Expression
    About this image

    H1F0 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    H1F0 Protein Expression
        Custom PCR Arrays for H1F0
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for H1F0

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for H1F0 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia H1f01 , 5 H1 histone family, member 01, 5 91.73(n)1
    96.45(a)1
      15 (37.70 cM)5
    149581  NM_008197.31  NP_032223.21 
     790282125 
    chicken
    (Gallus gallus)
    Aves H1F06
    H1F06
    Histone H5
    Gallus gallus H1 histone family, member 0 (H1F0), ...
    67(a)
    67(a)
    1 ↔ many
    1 ↔ many
    1(50991976-50992548)
    AADN03018723.1(10155-11037)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3986622 hypothetical protein LOC398662 71.7(n)    M22835.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb23b022 wufb23b02 74.42(n)   321618  BC056596.1 


    ENSEMBL Gene Tree for H1F0 (if available)
    TreeFam Gene Tree for H1F0 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for H1F0 gene
    HIST1H1T2  HIST1H1E2  HIST1H1D2  HIST1H1B2  HIST1H1C2  HIST1H1A2  
    6 SIMAP similar genes for H1F0 using alignment to 1 protein entry:     H10_HUMAN:
    HIST1H1A    HIST1H1T    HIST1H1B    HIST1H1C    HIST1H1D    HIST1H1E

    Find genes that share paralogs with H1F0           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for H1F0 (see all 56)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs787488611,2
    F--38199162(+) CTGGGG/ACGGGG 1 -- us2k11Minor allele frequency- A:0.01WA 118
    rs60008961,2
    C,A--38199222(+) GGGAGT/GGGGGG 1 -- us2k1 tfbs3 trp312Minor allele frequency- G:0.15NA WA CSA EA 374
    rs1510855311,2
    C--38199226(+) GGGGGA/GGCTAT 1 -- us2k10--------
    rs1407980821,2
    --38199345(+) AGAAAC/TTGACA 1 -- us2k10--------
    rs60008971,2
    C,F,A,H--38199364(+) AGACGG/AACCTT 1 -- us2k120Minor allele frequency- A:0.13NS EA NA WA CSA 1204
    rs1399780291,2
    C--38199418(+) CTGTG-/CCCACG 1 -- us2k10--------
    rs1930144611,2
    --38199456(+) ACACCA/GAGTCT 1 -- us2k10--------
    rs7392671,2
    C,F--38199470(+) GCTCCC/ACCTCC 1 -- us2k1 tfbs3 trp33Minor allele frequency- A:0.16MN WA NA 422
    rs1845205901,2
    --38199802(+) AGAGGA/GGCCCA 1 -- us2k10--------
    rs1890444561,2
    --38199911(+) GAGGTA/CTCTCC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for H1F0 (38201114 - 38203443 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for H1F0:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv4966n71CNV Loss21882294
    nsv915035CNV Loss21882294
    dgv4967n71CNV Loss21882294
    dgv4965n71CNV Loss21882294
    dgv1406e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 142708    OMIM disorders: --


    Find genes that share disorders with H1F0           About GenesLikeMe

    Genetic Association Database (GAD): H1F0
    Human Genome Epidemiology (HuGE) Navigator: H1F0 (1 document)

    Export disorders for H1F0 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for H1F0 gene, integrated from 10 sources (see all 68):
    (articles sorted by number of sources associating them with H1F0)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Differential distribution of lysine and arginine residues in the closely related histones H1 and H5. Analysis of a human H1 gene. (PubMed id 3084796)1, 2, 3 Doenecke D. and Tonjes R. (J. Mol. Biol. 1986)
    2. Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility &quot;hot-spot&quot;. (PubMed id 20628624)1, 4 Johnatty S.E.... . (PLoS Genet. 2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I.... Wright H. (Nature 1999)
    7. The microheterogeneity of the mammalian H1(0) histone. Evidence for an age-dependent deamidation. (PubMed id 9582379)1, 2 Lindner H.... Helliger W. (J. Biol. Chem. 1998)
    8. Profiling of Parkin-binding partners using tandem affinity purification. (PubMed id 24244333)1 Zanon A....Pichler I. (PLoS ONE 2013)
    9. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    10. KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR). (PubMed id 22902626)1 Fei J. and Chen J. (J. Biol. Chem. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3005 HGNC: 4714 AceView: H1F0 Ensembl:ENSG00000189060 euGenes: HUgn3005
    ECgene: H1F0 H-InvDB: H1F0

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for H1F0 Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/Histone_H1

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for H1F0 gene:
    Search GeneIP for patents involving H1F0

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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