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H19 Gene

RNA gene   GIFtS: 35
GCID: GC11M002016

H19, Imprinted Maternally Expressed Transcript (Non-Protein...

(Previous names: H19, imprinted maternally expressed untranslated mRNA)
  See H19-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Subcategory (RNA class): processed_transcript

Quality score for this RNA gene is 3

Aliases
H19, Imprinted Maternally Expressed Transcript (Non-Protein Coding)1 2     Long Intergenic Non-Protein Coding RNA 81
ASM12 5     Non-Protein Coding RNA 81
BWS2 5     ASM2
D11S813E2 5     LINC000082
WT22 5     NCRNA000082
H19, Imprinted Maternally Expressed Untranslated MRNA1     PRO26052

External Ids:    HGNC: 47131   Entrez Gene: 2831202   Ensembl: ENSG000001306007   OMIM: 1032805   

Export aliases for H19 gene to outside databases

Previous GC identifers: GC11U990149 GC11M001980 GC11M001972 GC11M001976 GC11M001807


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for H19 Gene:
This gene expresses a non-coding RNA, and functions as a tumor suppressor. The gene is located in an imprinted
region of chromosome 11 near the insulin-like growth factor 2 (IGF2) gene. Expression of this gene and IGF2 are
imprinted so that this gene is only expressed from the maternally-inherited chromosome, and IGF2 is only
expressed from the paternally-inherited chromosome. A region of paternal-specific methylation upstream of this
gene is required for the imprinting of these genes. Mutations in this gene are associated with Beckwith-Wiedemann
Syndrome and Wilms tumorigenesis. (provided by RefSeq, Mar 2009)

GeneCards Summary for H19 Gene:
H19 (H19, imprinted maternally expressed transcript (non-protein coding)) is an RNA gene, and is affiliated with the processed_transcript RNA class. Diseases associated with H19 include silver-russell syndrome due to 11p15 microduplication, and beckwith-wiedemann syndrome.

Gene Wiki entry for H19 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_009237.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the H19 gene promoter:
         NF-1   NF-1/L   p53   MyoD   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for H19

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat H19


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.5   HGNC cytogenetic band: 11p15.5

H19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
H19 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M002016:  view genomic region     (about GC identifiers)

Start:
2,016,406 bp from pter      End:
2,022,700 bp from pter
Size:
6,295 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for H19

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB: --


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
LNCRNA: Long non-coding RNAs

  --

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:
     Genatlas biochemistry entry for H19:
DNA segment,single copy,probe H19S1,highly expressed in endodermal and mesodermal embryonic tissues,in adult
brain,only in the pons and globus pallidus,paternally imprinted,(?same as ASMG),telomeric imprinting domain at
11p15,containing ASCL2,IGF2 and H19,silenced and hypermethylated in most Wilms tumor and in bladder
carcinomas,but hypomethylated in benign ovarian teratoma

Phenotypes:
     10 MGI mutant phenotypes (inferred from 10 alleles(MGI details for H19):
 cellular  digestive/alimentary  embryogenesis  growth/size/body  mortality/aging 
 nervous system  no phenotypic analysis  normal  skeleton  tumorigenesis 

Find genes that share phenotypes with H19           About GenesLikeMe

Animal Models:
     MGI mouse knock-outs for H19: H19tm7Tilg H19tm4Msb H19tm7Msb H19tm1Masu H19tm1Tilg H19tm1.1Sriv
                                                     H19tm1Lda

   genOway: Develop your customized and physiologically relevant rodent model for H19

miRNA
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Predesigned siRNA for gene silencing in human, mouse, rat H19

Gene Editing
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DNA2.0 Custom Protein Engineering Service for H19

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GenScript Custom all cDNA clones Services for H19
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for H19
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat H19

Cell Line
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for H19

Flow Cytometry
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eBioscience FlowRNA Probe Sets ( VA1-13208 VA4-10913 VB1-14257) for H19 


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for H19
Interactions:

    GeneGlobe Interaction Network for H19

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for H19

Selected Novoseek inferred chemical compound relationships for H19 gene (see all 18)    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
nap-2 78.3 3 9268640 (1), 9618174 (1), 10049585 (1)
apai 73.6 8 13679437 (1), 9570364 (1), 10473973 (1), 10738131 (1) (see all 7)
rsai 68.4 12 13679437 (1), 10690526 (1), 8564957 (1), 10473973 (1) (see all 8)
cytosine 47.1 3 11889182 (2), 9310237 (1)
5-aza-2'deoxycytidine 45.5 5 16707479 (1), 8842727 (1), 11889182 (1), 11726548 (1)
n-butyl-n-(4-hydroxybutyl)nitrosamine 41.8 2 9886562 (2)
hpaii 37.8 1 17020468 (1)
paraffin 13.8 6 9025899 (1), 9208812 (1), 7855987 (1), 10428315 (1) (see all 6)
ribonucleic acid 7.2 4 9177379 (2), 10843195 (1), 12534338 (1)
acth 5.62 6 7512497 (2), 7531713 (2), 9177379 (2)



Find genes that share compounds with H19           About GenesLikeMe



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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Unigene Cluster for H19:

H19, imprinted maternally expressed transcript (non-protein coding)
Hs.533566  [show with all ESTs]
Unigene Representative Sequence: NR_002196
14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000442037(processed_transcript) ENST00000411861(processed_transcript) ENST00000439725(processed_transcript) ENST00000412788(processed_transcript) ENST00000414790(processed_transcript)
ENST00000422826(processed_transcript) ENST00000446406(processed_transcript) ENST00000417089(processed_transcript) ENST00000411754(processed_transcript) ENST00000431095(processed_transcript)
ENST00000436715(processed_transcript) ENST00000428066(processed_transcript) ENST00000447298(processed_transcript) ENST00000390168(processed_transcript)
miRNA
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Search for qRT-PCR Assays for microRNAs that regulate H19
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
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Predesigned siRNA for gene silencing in human, mouse, rat H19
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OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for H19
DNA2.0 Custom Codon Optimized Gene Synthesis Service for H19
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat H19
Primer
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Pre-validated RT2 qPCR Primer Assay in human, mouse / rat H19
  Search QuantiTect SYBR Green Assays in human, mouse, rat H19
  QuantiFast Probe-based Assays in human, mouse, rat H19
Flow Cytometry
Products:
   

 
eBioscience FlowRNA Probe Sets ( VA1-13208 VA4-10913 VB1-14257) for H19 

Additional mRNA sequence: 

AK056774.1 AK092486.1 AK123560.1 AK309887.1 AK311497.1 BC006831.1 BC007513.2 BC009853.1 
BC010185.2 BC013067.1 BC015952.2 BC023213.1 BC040073.1 BC040852.1 BC053636.1 BC053637.1 
BC063564.1 BC063626.1 BC069247.1 BC098439.1 BC106078.1 BC106079.1 BC110657.1 BC115700.1 
NR_002196.1 

Selected DOTS entries (see all 104):

DT.95378063  DT.91915935  DT.100876775  DT.100743662  DT.95378256  DT.91731337  DT.85104197  DT.100743626 
DT.85101650  DT.100743767  DT.455239  DT.92391664  DT.92470792  DT.120706266  DT.120706354  DT.95378206 
DT.102841233  DT.100743769  DT.120706331  DT.91656375  DT.100743606  DT.100743632  DT.100743661  DT.100743690 

Selected AceView cDNA sequences (see all 2627):

R97708 AA341793 AA369043 F36353 CR598893 H63696 CR594207 CA448792 
BM838030 AI219634 H67013 CR618478 CR610115 N53685 AW675192 BE900558 
CB989602 CR602619 BC010185 AL546714 CR608274 AA478276 BI087416 F24651 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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Expression evidence for H19:none

H19 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GCCACCCCCT
H19 Expression
About this image


H19 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 25) fully expand
 
 Cartilage (Muscoskeletal System)    fully expand to see all 10 entries
         HyStem+BMP4-induced 4D20.8 cells
 
 Bone (Muscoskeletal System)    fully expand to see all 10 entries
         HyStem+BMP4-induced 4D20.8 cells
 
 Liver (Hepatobiliary System)    fully expand to see all 4 entries
         Fetal Hepatocytes Liver Lobule
 
 Adipose (Muscoskeletal System)    fully expand to see all 4 entries
         Interscapular Brown Adipose Depot
         HyStem+BMP4-induced E15 cells
 
 Pancreas (Endocrine System)    fully expand to see all 4 entries
         Endocrine Progenitor Cells Ventral Pancreatic Bud
H19 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

SOURCE GeneReport for Unigene cluster: Hs.533566
    Custom PCR Arrays for H19
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Pre-validated RT2 qPCR Primer Assay in human, mouse / rat H19
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QuantiFast Probe-based Assays in human, mouse, rat H19
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for H19

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of human and mouse.

Orthologs for H19 gene from 1 species (see representative species )    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia H195 H19 fetal liver mRNA   --   7 (87.97 cM) 142575529 


ENSEMBL Gene Tree for H19 (if available)
TreeFam Gene Tree for H19 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for H19 (see all 144)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1453309411,2
--1949981(+) CCTCCA/GCAAGC 1 -- ds50010--------
rs115647411,2
C,F--1950185(-) GGGGGG/ACATGG 1 -- ds50011Minor allele frequency- A:0.12EA 120
rs1163091181,2
F--1950255(+) GTCCTC/GGAGAC 1 -- ds50011Minor allele frequency- G:0.03WA 118
rs37412191,2
C,F,A,H--1950477(-) GCCTGT/CGCAGG 1 -- nc-transcript-variantese327Minor allele frequency- C:0.32EA NA MN NS EU 4523
rs725565501,2
F--1950515(-) RGTRCG/AAGTGT 1 -- nc-transcript-variant5Minor allele frequency- A:0.01MN 408
rs28397041,2
C,F,A--1950517(-) TCAGTA/G/TCGAGT 2 -- nc-transcript-variantese317EA NA MN CSA WA EU 1272
rs28397031,2
C,F,A--1950520(-) GTCTCA/G/TGTACG 2 -- nc-transcript-variantese317EU NA MN CSA WA EA 1605
rs725565511,2
C,F--1950525(-) CTTGAG/ATCTCR 1 -- nc-transcript-variant5Minor allele frequency- A:0.01MN 408
rs37412161,2
C,F,A,H--1950575(-) AATTTA/TATTTG 1 -- nc-transcript-variant15Minor allele frequency- T:0.09EA NA MN NS EU 2975
rs115427241,2
C--1950631(+) AGAAAA/TAAGGA 1 -- nc-transcript-variant0--------

HapMap Linkage Disequilibrium report for H19 (2016406 - 2022700 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for H19 (see all 14):    About this table    
Variant IDTypeSubtypePubMed ID
esv29980CNV Loss17803354
dgv991n71CNV Loss21882294
dgv989n71CNV Loss21882294
dgv988n71CNV Loss21882294
nsv522320CNV Loss19592680
nsv896767CNV Loss21882294
nsv896731CNV Loss21882294
dgv983n71CNV Loss21882294
dgv987n71CNV Loss21882294
nsv469926CNV Loss18288195

Human Gene Mutation Database (HGMD): H19
Site Specific Mutation Identification with PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing H19
DNA2.0 Custom Variant and Variant Library Synthesis for H19

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 103280   
OMIM disorders: 130650  180860  194071  
15 diseases for H19:    
About MalaCards
silver-russell syndrome due to 11p15 microduplication    beckwith-wiedemann syndrome    hemihypertrophy    beckwith-wiedemann syndrome due to imprinting defect of 11p15
silver-russell syndrome due to imprinting defect of 11p15    beckwith-wiedemann syndrome due to 11p15 microdeletion    wilms tumor 2    silver-russell syndrome
wilms tumor, type 1    angiomatosis    bladder carcinoma    hepatoblastoma
juvenile nasopharyngeal angiofibroma    albright's hereditary osteodystrophy    wagr syndrome


Find genes that share disorders with H19           About GenesLikeMe

Selected Novoseek inferred disease relationships for H19 gene (see all 62)    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
beckwith-wiedemann syndrome 92.4 19 9285792 (2), 8971182 (1), 10857747 (1), 15057946 (1) (see all 18)
embryonal tumor 79.8 2 8618347 (1), 11751681 (1)
wilms tumor 79.7 37 10506193 (3), 7534414 (2), 17325026 (2), 8842727 (2) (see all 24)
cancer embryonal 79 1 9484911 (1)
pediatric germ cell tumor 65.8 1 10189147 (1)
hepatoblastoma 63.1 12 10404060 (4), 10732739 (2), 9570364 (1), 19034281 (1) (see all 8)
hydatidiform mole 59.5 8 7866996 (3), 8188082 (1), 10751088 (1), 10022954 (1) (see all 5)
rhabdomyosarcoma embryonal 57.9 1 12234381 (1)
hemihypertrophy 49.8 2 16532391 (1), 7802016 (1)
bladder carcinoma 49 29 7589512 (5), 11193051 (4), 9886562 (3), 10413100 (3) (see all 9)

GeneTests: H19
GeneReviews: H19
Genetic Association Database (GAD): H19
Human Genome Epidemiology (HuGE) Navigator: H19 (13 documents)

Export disorders for H19 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for H19 gene, integrated from 10 sources (see all 382):
(articles sorted by number of sources associating them with H19)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The H19 gene imprinting in normal pregnancy and pre-eclampsia. (PubMed id 19342096)1, 4, 9 Yu L....Li L. (Placenta 2009)
  2. Genetic predisposition to idiopathic recurrent spontaneous abortion: contribution of genetic variations in IGF-2 and H19 imprinted genes. (PubMed id 18573128)1, 4, 9 OstojiA8 S....Peterlin B. (Am. J. Reprod. Immunol. 2008)
  3. Polymorphisms in the H19 gene and the risk of bladder cancer. (PubMed id 18262338)1, 4, 9 Verhaegh G.W....Kiemeney L.A. (Eur. Urol. 2008)
  4. Association of breast cancer susceptibility variants with risk of pancreatic cancer. (PubMed id 19843670)1, 4, 9 Couch F.J....Petersen G.M. (amp 2009)
  5. The product of the H19 gene may function as an RNA. (PubMed id 1688465)1, 3, 9 Brannan C.I....Tilghman S.M. (Mol. Cell. Biol. 1990)
  6. Association of birth weight with polymorphisms in the IGF2, H19, and IGF2R genes. (PubMed id 20639793)1, 4 Adkins R.M....Krushkal J. (Pediatr. Res. 2010)
  7. FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women. (PubMed id 20554749)1, 4 Barnholtz-Sloan J.S....Millikan R.C. (Carcinogenesis 2010)
  8. Common genetic variants associated with breast cancer and mammographic density measures that predict disease. (PubMed id 20145138)1, 4 Odefrey F....Southey M.C. (Cancer Res. 2010)
  9. Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. (PubMed id 20587610)1, 4 Ucisik-Akkaya E....Dorak M.T. (Mol. Hum. Reprod. 2010)
  10. Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans. (PubMed id 15885138)1, 4 Petry C.J....Dunger D.B. (BMC Genet. 2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 283120 HGNC: 4713 AceView: H19 Ensembl:ENSG00000130600 euGenes: HUgn283120
ECgene: H19 H-InvDB: H19

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for H19 Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for H19 Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for H19 gene:
Search GeneIP for patents involving H19

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for H19  
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 Block miRNA regulation of human, mouse, rat H19 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing H19
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 Pre-validated RT2 qPCR Primer Assay in human, mouse / rat H19  GeneGlobe Interaction Network for H19
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 GenScript Custom Purified and Recombinant Proteins Services for H19 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for H19
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 Search Tocris compounds for H19
 Browse Sino Biological Proteins
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Biologicals
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 Search for Antibodies for H19 at Abcam
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 Browse ProSpec Recombinant Proteins
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 Browse ESI BIO Cell Lines and PureStem Progenitors for H19
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 Browse SwitchGear 3'UTR luciferase reporter plasmids for H19
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 Search ThermoFisher Antibodies for H19
 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat H19
 Browse compounds at ApexBio
 Search Addgene for plasmids for H19
  Search eBioscience for proteins for H19
  Search eBioscience for elisas for H19
  eBioscience FlowRNA Probe Sets
 genOway: Develop your customized and physiologically relevant rodent model for H19
  Search antibodies-online for antibodies for H19
  Search antibodies-online for kits for H19
  Search antibodies-online for peptides for H19
  Search antibodies-online for proteins for H19
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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