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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

H19 Gene

RNA gene GIFtS: 36
GCID: GC11M002016

H19, Imprinted Maternally Expressed Transcript (Non-Protein...

(Previous names: H19, imprinted maternally expressed untranslated mRNA)

76 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Subcategory (RNA class): lncRNA

Quality score for this RNA gene is 10.2

Aliases
H19, Imprinted Maternally Expressed Transcript (Non-Protein Coding)¹ ²		Long Intergenic Non-Protein Coding RNA 8¹
ASM1² ⁵		Non-Protein Coding RNA 8¹
BWS² ⁵		ASM²
D11S813E² ⁵		LINC00008²
WT2² ⁵		NCRNA00008²
H19, Imprinted Maternally Expressed Untranslated MRNA¹		PRO2605²

External Ids:	HGNC: 4713¹	Entrez Gene: 283120²	Ensembl: ENSG00000130600⁷	OMIM: 103280⁵

ORGUL members:	fRNAdb¹⁰:FR217109 FR171508 FR041821 FR143442 FR281471
	H-InvDB¹²:HIT000338440
	NCBI¹³:AF087017 M32053 AF087017 AF125183 BC106079
	NONCODE¹⁴:u4124 u745 u837 n346135 n333410 n343066 n346077	see top 5
	RNAdb¹⁵:LIT1609 EVF34532 EVF31770 LIT1610

Export aliases for H19 gene to outside databases

Previous GC identifers: GC11U990149 GC11M001980 GC11M001972 GC11M001976 GC11M001807

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for H19 Gene:

This gene expresses a non-coding RNA, and functions as a tumor suppressor. The gene is located in an imprinted region

of chromosome 11 near the insulin-like growth factor 2 (IGF2) gene. Expression of this gene and IGF2 are imprinted so

that this gene is only expressed from the maternally-inherited chromosome, and IGF2 is only expressed from the

paternally-inherited chromosome. A region of paternal-specific methylation upstream of this gene is required for the

imprinting of these genes. Mutations in this gene are associated with Beckwith-Wiedemann Syndrome and Wilms

tumorigenesis. (provided by RefSeq, Mar 2009)

GeneCards Summary for H19 Gene:

H19 (H19, imprinted maternally expressed transcript (non-protein coding)) is an RNA gene, and is affiliated with the lncRNA class. Diseases associated with H19 include chromosome 11p15.5-related russell-silver syndrome, and beckwith-wiedemann syndrome due to 11p15 microdeletion.

Gene Wiki entry for H19 Gene

fRNAdb sequence ontologies for H19 - the ORGUL cluster for this gene includes several descriptions:
mature_transcript - A transcript which has undergone the necessary modifications, if any, for its function. In eukaryotes this includes, for example, processing of introns, cleavage, base modification, and modifications to the 5' and/or the 3' ends, other than addition of bases. In bacteria functional mRNAs are usually not modified.
nc_conserved_region - Non-coding region of sequence similarity by descent from a common ancestor.
ncRNA - An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

View fRNAdb secondary structures for H19

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.2 NT_009237.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the H19 gene promoter:
NF-1 NF-1/L p53 MyoD
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for H19

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat H19

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5 Ensembl cytogenetic band: 11p15.5 HGNC cytogenetic band: 11p15.5

H19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
H19 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M002016: view genomic region (about GC identifiers)

Start:	2,016,406 bp from pter	End:	2,022,700 bp from pter
Size:	6,295 bases	Orientation:	minus strand

ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for H19

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB: --

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

LNCRNA: Long non-coding RNAs

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

Genatlas biochemistry entry for H19:

DNA segment,single copy,probe H19S1,highly expressed in endodermal and mesodermal embryonic tissues,in adult brain,only

in the pons and globus pallidus,paternally imprinted,(?same as ASMG),telomeric imprinting domain at 11p15,containing

ASCL2,IGF2 and H19,silenced and hypermethylated in most Wilms tumor and in bladder carcinomas,but hypomethylated in

benign ovarian teratoma

Phenotypes:
15/19 MGI mutant phenotypes (inferred from 29 alleles) (MGI details for H19) (see all 19):

cardiovascular system	cellular	craniofacial	digestive/alimentary	embryogenesis
endocrine/exocrine gland	growth/size	homeostasis/metabolism	limbs/digits/tail	liver/biliary system
mortality/aging	muscle	nervous system	no phenotypic analysis	normal

H19 for phenotypes           About GeneDecksing

Animal Models:
     Mouse knock-outs for H19: H19^tm1Rohl H19^tm7Tilg H19^tm7Msb H19^tm3Msb H19^tm5Msb H19^tm2Wrk
                                               H19^tm1Msb H19^tm1.1Sriv H19^tm6Msb H19^tm1Lda H19^tm1.1Kpfe H19^tm1Tilg H19^tm4Msb
                                               H19^tm1.1Msb H19^tm2Tilg H19^tm1Masu

inGenious Targeting Laboratory - Custom generated mouse model solutions for H19

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for H19

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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for H19

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
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		GenScript Custom all cDNA clones Services for H19
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for H19
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat H19

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for H19
		Search LifeMap BioReagents cell lines for H19

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for H19

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for H19

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

H19 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for H19

10/18 Novoseek inferred chemical compound relationships for H19 gene (see all 18) About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
nap-2	78.3	3	9268640 (1), 9618174 (1), 10049585 (1)
apai	73.6	8	13679437 (1), 9570364 (1), 10473973 (1), 10738131 (1) (see all 7)
rsai	68.4	12	13679437 (1), 10690526 (1), 8564957 (1), 10473973 (1) (see all 8)
cytosine	47.1	3	11889182 (2), 9310237 (1)
5-aza-2'deoxycytidine	45.5	5	16707479 (1), 8842727 (1), 11889182 (1), 11726548 (1)
n-butyl-n-(4-hydroxybutyl)nitrosamine	41.8	2	9886562 (2)
hpaii	37.8	1	17020468 (1)
paraffin	13.8	6	9025899 (1), 9208812 (1), 7855987 (1), 10428315 (1) (see all 6)
ribonucleic acid	7.2	4	9177379 (2), 10843195 (1), 12534338 (1)
acth	5.62	6	7512497 (2), 7531713 (2), 9177379 (2)

Search CenterWatch for drugs/clinical trials and news about H19

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

3 fRNAdb Secondary structures:

Unigene Cluster for H19:

H19, imprinted maternally expressed transcript (non-protein coding)

Hs.533566 [show with all ESTs]

Unigene Representative Sequence: NR_002196

14 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000442037 ENST00000411861 ENST00000439725 ENST00000412788 ENST00000414790(uc021qby.1 uc001lva.4 uc021qbz.1)

ENST00000422826 ENST00000446406 ENST00000417089 ENST00000411754 ENST00000431095

ENST00000436715 ENST00000428066 ENST00000447298 ENST00000390168(uc021qca.1)

miRNA Products:
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		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate H19
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for H19
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat H19

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		GenScript Custom all cDNA clones Services for H19
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for H19
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat H19

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for H19
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat H19
		Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat H19
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat H19

Additional mRNA sequence:

AK056774.1 AK092486.1 AK123560.1 AK309887.1 AK311497.1 BC006831.1 BC007513.2 BC009853.1

BC010185.2 BC013067.1 BC015952.2 BC023213.1 BC040073.1 BC040852.1 BC053636.1 BC053637.1

BC063564.1 BC063626.1 BC069247.1 BC098439.1 BC106078.1 BC106079.1 BC110657.1 BC115700.1

NR_002196.1

24/104 DOTS entries (see all 104):

DT.95378063 DT.91915935 DT.100876775 DT.100743662 DT.95378256 DT.91731337 DT.85104197 DT.100743626

DT.85101650 DT.100743767 DT.455239 DT.92391664 DT.92470792 DT.120706266 DT.120706354 DT.95378206

DT.102841233 DT.100743769 DT.120706331 DT.91656375 DT.100743606 DT.100743632 DT.100743661 DT.100743690

24/2627 AceView cDNA sequences (see all 2627):

R79144 BC010185 R97708 AW880064 BU751954 CR607245 R96795 BU170025

F36353 CR598893 H63696 CR594207 CR615643 BF055123 AW673914 R78395

T50688 F22747 CR625840 CR599037 BG014970 R83855 T50417 H79638

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

Expression evidence for H19:RNAdb

H19 expression in normal human tissues (normalized intensities) H19 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GCCACCCCCT

About this image

H19 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/20 selected tissues (see all 20) fully expand


Cartilage (Muscoskeletal System) fully expand to see all 13 entries
"PureStem Z11, Meso Progenitor"
HyStem+BMP4-induced 4D20.8 cells

Bone (Muscoskeletal System) fully expand to see all 11 entries
"PureStem SK11, NCr-fac & Meso-prx Progenitor"
HyStem+BMP4-induced 4D20.8 cells

Adipose (Muscoskeletal System) fully expand to see all 5 entries
Interscapular Brown Adipose Depot
"PureStem SK11, NCr-fac & Meso-prx Progenitor"
HyStem+BMP4-induced E15 cells

Liver (Hepatobiliary System) fully expand to see all 4 entries
Fetal Hepatocytes Liver Lobule

Pancreas (Endocrine System) fully expand to see all 4 entries
Endocrine Progenitor Cells Ventral Pancreatic Bud

Genevestigator expression for H19

SOURCE GeneReport for Unigene cluster: Hs.533566

SABiosciences Custom PCR Arrays for H19

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for H19
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat H19

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for H19

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and mouse.

Orthologs for H19 gene from 1 species (see representative species ) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	H19⁵	H19 fetal liver mRNA	--		7 (87.97 cM) 142575529

ENSEMBL Gene Tree for H19 (if available)
TreeFam Gene Tree for H19 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs145330941^1,2		--	1949981(+)	`CCTCCA/GCAAGC`	1	--	ds500¹		0	--	--	--	--
rs11564741^1,2	C,F	--	1950185(-)	`GGGGGG/ACATGG`	1	--	ds500¹		1		EA	120
rs116309118^1,2	F	--	1950255(+)	`GTCCTC/GGAGAC`	1	--	ds500¹		1		WA	118
rs3741219^1,2	C,F,A,H	--	1950477(-)	`GCCTGT/CGCAGG`	1	--	nc-transcript-variantese³		27		EA NA MN NS EU	4523
rs72556550^1,2	F	--	1950515(-)	`RGTRCG/AAGTGT`	1	--	nc-transcript-variant		5		MN	408
rs2839704^1,2	C,F,A	--	1950517(-)	`TCAGTA/G/TCGAGT`	2	--	nc-transcript-variantese³		17		EA NA MN CSA WA EU	1272
rs2839703^1,2	C,F,A	--	1950520(-)	`GTCTCA/G/TGTACG`	2	--	nc-transcript-variantese³		17		EU NA MN CSA WA EA	1605
rs72556551^1,2	C,F	--	1950525(-)	`CTTGAG/ATCTCR`	1	--	nc-transcript-variant		5		MN	408
rs3741216^1,2	C,F,A,H	--	1950575(-)	`AATTTA/TATTTG`	1	--	nc-transcript-variant		15		EA NA MN NS EU	2975
rs11542724^1,2	C	--	1950631(+)	`AGAAAA/TAAGGA`	1	--	nc-transcript-variant		0	--	--	--	--

HapMap Linkage Disequilibrium report for H19 (2016406 - 2022700 bp)

Structural Variations
Database of Genomic Variants (DGV) 10/14 variations for H19 (see all 14): About this table

Variant ID	Type	Subtype	PubMed ID
esv29980	CNV	Loss	17803354
dgv991n71	CNV	Loss	21882294
dgv989n71	CNV	Loss	21882294
dgv988n71	CNV	Loss	21882294
nsv522320	CNV	Loss	19592680
nsv896767	CNV	Loss	21882294
nsv896731	CNV	Loss	21882294
dgv983n71	CNV	Loss	21882294
dgv987n71	CNV	Loss	21882294
nsv469926	CNV	Loss	18288195

Human Gene Mutation Database (HGMD): H19

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing H19

DNA2.0 Custom Variant and Variant Library Synthesis for H19

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

H19 for disorders           About GeneDecksing

OMIM gene information: 103280OMIM information: 609124 194071 604499 607967 609270 609470
OMIM disorders: 130650  180860  194071
20/76 diseases for H19 (see all 76):    About MalaCards

chromosome 11p15.5-related russell-silver syndrome beckwith-wiedemann syndrome due to 11p15 microdeletion beckwith-wiedemann syndrome due to imprinting defect of 11p15 hemihypertrophy

beckwith-wiedemann syndrome silver-russell syndrome malignant mixed mullerian tumor wilms tumor 2

angiomatosis hepatoblastoma bladder carcinoma juvenile nasopharyngeal angiofibroma

wagr syndrome gigantism germ cell tumors clear cell sarcoma

albright's hereditary osteodystrophy adrenal adenoma growth disorders aniridia

10/62 Novoseek inferred disease relationships for H19 gene (see all 62) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
beckwith-wiedemann syndrome	92.4	19	9285792 (2), 8971182 (1), 10857747 (1), 15057946 (1) (see all 18)
embryonal tumor	79.8	2	8618347 (1), 11751681 (1)
wilms tumor	79.7	37	10506193 (3), 7534414 (2), 17325026 (2), 8842727 (2) (see all 24)
cancer embryonal	79	1	9484911 (1)
pediatric germ cell tumor	65.8	1	10189147 (1)
hepatoblastoma	63.1	12	10404060 (4), 10732739 (2), 9570364 (1), 19034281 (1) (see all 8)
hydatidiform mole	59.5	8	7866996 (3), 8188082 (1), 10751088 (1), 10022954 (1) (see all 5)
rhabdomyosarcoma embryonal	57.9	1	12234381 (1)
hemihypertrophy	49.8	2	16532391 (1), 7802016 (1)
bladder carcinoma	49	29	7589512 (5), 11193051 (4), 9886562 (3), 10413100 (3) (see all 9)

GeneTests: H19

Beckwith-Wiedemann Syndrome

Russell-Silver Syndrome

Genetic Association Database (GAD): H19
Human Genome Epidemiology (HuGE) Navigator: H19 (13 documents)

Export disorders for H19 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for H19 gene, integrated from 9 sources (see all 384):
(articles sorted by number of sources associating them with H19)

Utopia: connect your pdf to the dynamic
world of online information

The H19 gene imprinting in normal pregnancy and pre-eclampsia. (PubMed id 19342096)^{1, 4, 9} Yu L....Li L. (2009)
Genetic Predisposition to Idiopathic Recurrent Spontaneous Abortion: Contribution of Genetic Variations in IGF-2 and H19 Imprinted Genes. (PubMed id 18573128)^{1, 4, 9} Ostojic S....Peterlin B. (2008)
Polymorphisms in the H19 Gene and the Risk of Bladder Cancer. (PubMed id 18262338)^{1, 4, 9} Verhaegh G.W....Kiemeney L.A. (2008)
Association of breast cancer susceptibility variants with risk of pancreatic cancer. (PubMed id 19843670)^{1, 4, 9} Couch F.J....Petersen G.M. (2009)
The product of the H19 gene may function as an RNA. (PubMed id 1688465)^{1, 3, 9} Brannan C.I....Tilghman S.M. (1990)
Association of birth weight with polymorphisms in the IGF2, H19, and IGF2R genes. (PubMed id 20639793)^{1, 4} Adkins R.M....Krushkal J. (2010)
FGFR2 and other loci identified in genome-wide associ ation studies are associated with breast cancer in African-American and younger women. (PubMed id 20554749)^{1, 4} Barnholtz-Sloan J.S....Millikan R.C. (2010)
Common genetic variants associated with breast cancer and mammographic density measures that predict disease. (PubMed id 20145138)^{1, 4} Odefrey F....Southey M.C. (2010)
Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. (PubMed id 20587610)^{1, 4} Ucisik-Akkaya E....Tevfik Dorak M. (2010)
Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans. (PubMed id 15885138)^{1, 4} Petry C.J....Dunger D.B. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 283120	HGNC: 4713	AceView: H19	Ensembl:ENSG00000130600	euGenes: HUgn283120
ECgene: H19	H-InvDB: H19

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for H19	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for H19	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for H19 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for H19 gene:
Search GeneIP for patents involving H19

GeneCards and IP:
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H19 Gene

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